If you read the info on Utrogestan, it says ' taking with food increases the bio availability'- that means more is absorbed.
Here www.medicines.org.uk/emc/medicine/19895
Under 'Precautions' it says :
. Concomitant food ingestion increases the bioavailability of Utrogestan 100mg Capsules.
This means you will absorb more, not less, which is not necessarily a bad thing when its role is to act on the endometrium.
My consultant says it's fine to take it either way and makes little difference.
A slightly higher dose of oestrogen won't raise your breast cancer risk- it's synthetic progestogens that are linked to breast cancer, not oestrogen. And at 49 your risk doesn't 'start' with HRT until you reach the age of the average meno- 52.
The 'occasional' drink is ok but it depends on what you mean by that! Ie one glass of wine a week would be fine but one glass or more a day is going to increase your risk, regardless of HRT or not.
If you are travelling then isn't it best to keep to UK time and use when you'd normally use it?
But if you can't do that, just miss one dose or apply one extra that day and apply it later or earlier- whichever works.