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Infertility

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Secondary infertility - 4 failed euploid transfers.

2 replies

Katty123 · 06/10/2026 14:42

I know I am very fortunate to already have a daughter conceived via IVF two and half years ago. Prior to having her, we were TTC for 6 years and I had approx 4 IVF cycles before the pregnancy stuck (i had three miscarriages). We ended uo doing an immune protocol and that seems to do the trick.

Fast forward to now and we have been doing IVF again for 16months. I have had 4 euploid transfers fail and I cannot seem to get pregnant. I am pretty much on a kitchen sink approach including immune protocol, clexane, extra progesterone and PRP infusions. I even had a hysteroscopy, have done ALICE/microbiome testing and still no luck.

I have one euploid left and 2 untested day 6 embryos. I think most likely I will only use the last euploid but I just feel like it is the end of the road. I can't see anything changing on the fifth transfer and realistically given my history, it wont work.

I suppose I am writing this to help me process. But has anyone also been through similar and just had really bad luck? Was it fifth time lucky for anyone?

OP posts:
Miraclemuma03 · 06/10/2026 22:51

Im so sorry that your embryos arnt sticking. But I just wanted to come on and say that your untested embryos still will be good to transfer if it comes to the time you may need to use them, they may surprise you. I dont have any advice on what you could do going further. I hope someone else comes on and has some better advice for you with moving forward.

NiftyAmberLion · 10/10/2026 16:15

Katty123 · 06/10/2026 14:42

I know I am very fortunate to already have a daughter conceived via IVF two and half years ago. Prior to having her, we were TTC for 6 years and I had approx 4 IVF cycles before the pregnancy stuck (i had three miscarriages). We ended uo doing an immune protocol and that seems to do the trick.

Fast forward to now and we have been doing IVF again for 16months. I have had 4 euploid transfers fail and I cannot seem to get pregnant. I am pretty much on a kitchen sink approach including immune protocol, clexane, extra progesterone and PRP infusions. I even had a hysteroscopy, have done ALICE/microbiome testing and still no luck.

I have one euploid left and 2 untested day 6 embryos. I think most likely I will only use the last euploid but I just feel like it is the end of the road. I can't see anything changing on the fifth transfer and realistically given my history, it wont work.

I suppose I am writing this to help me process. But has anyone also been through similar and just had really bad luck? Was it fifth time lucky for anyone?

I am pregnant from my fourth Euploid and fifth transfer - first fail was a day 5 top grade fresh then 3 failed euploids. Just to give you hope! X

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