Not personally but I have a friend who has it in her family. Both her parents were found to carry the faulty gene, really bad luck. Angie is the eldset of six, she doesnt have it but 3 out of the 6 do. In fact I saw her sister in Dover last week, she has been in a wheel chair for 7 years now. She and her brothers didnt start to develop any symptems until they were in their late 20`s.