Last year, my ankle randomly became swollen, painful and bruised. I went to gp who thought it might be reactive arthritis. Tests done and all negative. Forgot about it. 2 weeks ago, was bitten by 3 mosquitos on the same ankle. Same big reaction but worse this time. Ankle is swollen, pitting edema, a little red, even my toes are swollen now. Reaction only appeared 12 days after I was bitten which is odd. Anyone else react like this? Antihistamines are doing sod all! Currently just elevating. It's been 2 days of swelling and pain now. Wonder if initial swelling a year ago was mozzie bites!