B12 injections and acne

[Sleepingsun]

Hi, I have been recently diagnosed with B12 deficiency. I had to have six B12 injections in two weeks to start with. After the fourth one, I suddenly had an acne breakout on my face and also have spots on my back and chest. They are pretty painful too :(
Has anyone else experienced this? Just wondering whether this is temporary or a long term as will probably need regular injections going forward.

I never had that reaction. I was just really tired, sleeping 20 hrs per day I think your body resumes normal functions it skipped before. I would think it would settle down.

@Sleepingsun I experienced the same as you, my spots were situated over my chest, back and covered the top of both my arms. They were very painful and some were pus filled. I had to have antibiotic tablets to clear my skin up for several weeks. My GP looked it up in the BNF and it is a rare side effect to the B12 injections. I had to change to tablet form which I was able to tolerate as it’s a smaller dose than in injection form. Not sure if it will be the same for you.

I had painful acne full of so much puss. It calmed down eventually. I occasionally get the odd sore spot but mostly fine now

It’s a common side effect of the injections and one of the reasons I stopped them. It does settle down eventually but will take time.

6 months to calm down

I wondered if my injections had been spread out (once a month?) if the reaction would have been less.

Thankfully I didn’t need b12 injections regularly. Through trial and error I realised gluten was causing my b12 deficiency