DD1 (aged 2) has a really bad infection and we ended up at out-of-hours docs on Sunday with gunk coming out of her left ear, high temp, generally unhappy etc. Dr said her infection was bad and had also spread quite a lot and caused general swelling along her ear / nose / throat area. She was prescribed amoxiciilin 3times a day, along with piriton twice a day to reduce the swelling and nose drops 4 times a day. We've been giving this alongside calpol several times a day for pain etc. She seemed a bit brighter yesterday so we sent her to nursery as normal today (which she normally loves) but they phoned just now to say she's really distressed again, and if she doesn't pick up after calpol asked if I would be willing to pick her (which obviously I said was fine). My question is how long do I give the antibiotics to work? She's now on her 4th day of amoxicillin so I was hoping she would be getting better by now.