During the day it's fine, have no problems walking, running and have a full range of movement and yet most nights I wake up in the early hours in awful pain regardless of the position I am laid in. Pain sometimes goes the length of my leg being worse at knee and ankle. Sometimes it stays in my thigh, sometimes on the inner side and sometimes the outer. It makes no difference how active I've been during the day and there is nothing else that I can link it to either.I sometimes take Ibruprofen before I go to bed and it marginally lessens the pain but not enough to stop it from waking me.