I've swapped from an old Dell desktop to a new MacBook! It is fantastic, would never go back! Yes it is pretty, but it is SO easy to use. It's not that different from a pc, really does all the same things pretty much. I got the middle of the range MacBook (£899) with 1 GB of RAM, my brother, who knows about these things said that would be plenty for what I do, but you may wish to get more. I realise for the same money I could have got a very whizzy desktop pc, but this laptop has loads more power than my old desktop, and isn't likely to age as quickly.
You don't need antivirus software with a mac, as the chances of getting a virus are tiny, so that doesn't eat up your RAM. Wireless connection is a doddle. I can use it on my lap, but using a desk is more comfortable. The only thing that took a bit of getting used to was the screen size (but that would be an issue with any laptop, really), and the slightly different layout of the keyboard.
I use MS office at work, and sometimes need to work at home, so have downloaded Neoffice which is a free Office compatible programme- no problems at all with it so far.
Can you tell I'm a convert?