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Autoimmune disease

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Removed gluten from my diet - psoriasis is dramatically worse

17 replies

hippospot · 16/04/2026 10:46

I'm only on day 10 so I wonder if perversely my immune system is on overdrive. Has anyone else had this experience and how long / did it settle down?

I've also stopped Enstilar as I felt it was no longer working. I was using Enstilar about three times a week.

I'm 52 and I have guttate psoriasis that appeared only 6 years ago after a hysterectomy.

OP posts:
Ohthatsabitshit · 16/04/2026 10:49

Could you be replacing your old diet with one that has spiked inflammation? I had the exact opposite reaction.

RestingGrumpFace · 16/04/2026 11:02

There's no evidence that cutting gluten helps psoriasis.

Is it possible that the Enstillar was doing more than you realised and what you're experiencing is steroid kickback? If you don't taper steroids slowly this often happens.

NewLeafAgain · 16/04/2026 11:15

Are you replacing it with gluten free breads etc? Or whole foods? If the former id try cutting those or making your own a while and see what happens.

VikingLady · 16/04/2026 11:31

It may be that you’re reacting to what you’ve replaced it with. I don’t do well with gluten, but all of the replacements are horrific for me! I’ve never found anything as effective for making me ill as supermarket gluten free bread.

LuckyCharmz · 16/04/2026 11:43

A healing crisis? Gets worse before it gets better.

hippospot · 16/04/2026 12:13

I haven't introduced any new foods to replace eg bread. I have a really good whole food diet (I think). I'll give it some more time I guess. Thanks for your replies

OP posts:
Clothesmoths · 13/06/2026 08:11

You’d need to stop just one thing at a time for a while then another thing, to really know, surely. But as with any worse symptoms flaring up, I’d be going to speak to your care team. Sorry you’re having to deal with this.

AlgaeDreams · 13/06/2026 08:14

You haven't started beta blockers recently have you? I was put on them and almost immediately my entire body covered with plaque psoriasis.
There's a proven link but nobody bothers telling you 🙄

Girlintheframe · 13/06/2026 08:35

That’s really interesting. I did really strict keto (20g carbs a day) for around a year and my psoriasis complete cleared up. Even today years later I only have one or two patches now. I hadn’t thought gluten may be the reason

Walkacrossthesand · 13/06/2026 10:33

One change at a time, as @Clothesmothssays, or you don’t know what’s caused the change. I imagine your psoriasis wasn’t controlled hence wanting to try gluten free - I’d go back to gluten and enstilar, things should improve, then withdraw gluten as suggested above, having sourced replacements, and see. Good luck.

SanSeb · 14/06/2026 18:31

I did a strict elimination diet for a skin condition, one of the safe foods was my problem. And Eliminating almost everything in my diet meant I ate more of it and my skin condition got worse.

joyava · 14/06/2026 19:08

I’ve had psoriasis for 30 years. I gave up gluten in February of this year, with the intention of keeping it up for 3 months. It took almost 3 months to see any improvement. But since then I’ve noticed small patches of normal skin have appeared within my psoriasis patches. Also the constant itch is gone.
I’m going to keep going with it to see if the improvements continue.
Initially I did use gluten free supermarket bread, but found the taste quite chemical. As someone who usually had pasta twice a week & drank beer (especially with a curry) it has been quite a challenge at times.

AlgaeDreams · 16/06/2026 02:53

joyava · 14/06/2026 19:08

I’ve had psoriasis for 30 years. I gave up gluten in February of this year, with the intention of keeping it up for 3 months. It took almost 3 months to see any improvement. But since then I’ve noticed small patches of normal skin have appeared within my psoriasis patches. Also the constant itch is gone.
I’m going to keep going with it to see if the improvements continue.
Initially I did use gluten free supermarket bread, but found the taste quite chemical. As someone who usually had pasta twice a week & drank beer (especially with a curry) it has been quite a challenge at times.

Have you been to a specialist dermatologist?
My sons was all over his body and face and the gp found the neatest and quuckest appointment in the country he could because apparently it had got life threatening (son was in 20s). I think it was methotrexate he was put on. Something usually used for cancer patients. Psoriasis is an auto immune condition, this drug worked by lowering the immune system and thus slowing down the skin growth.

That's why for some reason beta blockers can cause it.

Unless your diet is lowering your immune system, I really can't see what difference it will make.

It cleared up really quickly and he'd never looked healthier (even though was probably more susceptible to illness).

He stopped taking it during the first covid lock down as he, like all ofvus were for acwhile, was more frightened of getting covid.

He still suffers occasionally , but nothing like he did. He looked like an all over burns victim.

joyava · 16/06/2026 04:33

AlgaeDreams · 16/06/2026 02:53

Have you been to a specialist dermatologist?
My sons was all over his body and face and the gp found the neatest and quuckest appointment in the country he could because apparently it had got life threatening (son was in 20s). I think it was methotrexate he was put on. Something usually used for cancer patients. Psoriasis is an auto immune condition, this drug worked by lowering the immune system and thus slowing down the skin growth.

That's why for some reason beta blockers can cause it.

Unless your diet is lowering your immune system, I really can't see what difference it will make.

It cleared up really quickly and he'd never looked healthier (even though was probably more susceptible to illness).

He stopped taking it during the first covid lock down as he, like all ofvus were for acwhile, was more frightened of getting covid.

He still suffers occasionally , but nothing like he did. He looked like an all over burns victim.

I have been refused methotrexate due to family history. I can’t explain how or why, nor had I any real expectation that removing gluten would have caused my psoriasis to calm down, but it has & continues to reduce slowly. It has been difficult at times & if I were not seeing results now, then I’d give up and return to eating normally.

AlgaeDreams · 16/06/2026 04:45

joyava · 16/06/2026 04:33

I have been refused methotrexate due to family history. I can’t explain how or why, nor had I any real expectation that removing gluten would have caused my psoriasis to calm down, but it has & continues to reduce slowly. It has been difficult at times & if I were not seeing results now, then I’d give up and return to eating normally.

I truly hope it works out for you.

My gp just prescribed enstillar, which is so good it's removed my life long freckles 🤔 then sneered at me that I could always give up my heart medication (resting pulse 120) plus BP meds.
Oh yes, because there's a choice 🙄 I don't like her!

sonia122 · 16/06/2026 05:02

I’m so sorry you're dealing with this. It is highly likely that stopping Enstilar suddenly is causing a classic "steroid rebound" flare, rather than the gluten-free diet itself. When you stop a strong topical treatment cold turkey, your skin can go into overdrive and flare up severely. Please check in with your doctor or dermatologist as soon as possible so they can help you calm this flare down safely....

NotSure222 · 21/06/2026 10:31

research into histamine - I would consider a low histamine diet

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