Battling severe fatigue AIBU to ask for opinions (especially medical) on these supplements & vitamins?

[TempryBlip]

I'd be very grateful for your medical/scientific opinion or personal experience of vitamins and supplements. I'm aware of the common outcome of expensive wee!

Now in my 60s, for several years I have struggled to find the energy I need for the demands of my life.

This got dramatically worse a couple of months ago and I'm only just functioning. It's possible a change of blood pressure medication or the after effects of a viral illness are contributing. I also take semaglutide (over 2 years) which has fatigue listed as a side effect. My BMI is still over 30.

My GP has arranged blood tests and an August appointment. Perhaps HRT would help or perhaps there's another fixable culprit. Meanwhile I need to declutter for a planned house move in a few weeks 🤞🏼.

Recently a Mumsnetter mentioned Lion's Mane being helpful.

I already take Magnesium and fish oil and, following blood tests last year,
Vitamin D, B12 and folic acid.

So,
Lion's Mane
Magnesium,
Fish Oil,
Vitamin D
Vitamin B13
Folic acid.

I'm trying to keep an open mind. I'd be very grateful for your opinion or experience.

Doesn't look bad.

If B12 deficiency is the problem, and in general, you should likely add an iron supplement to it. A bio available form, and take with Vitamin C to aid absorption, on an empty stomach. Avoid caffeine for at least 2 hours after taking (so may be best to take the iron last thing at night)

You also need to ensure you have B1 & B6 for B12 to work well, but any cheap vitamin B complex or multi vitamin can help you with that.

B12 + iron with all the others that they tell you to take with those (most of which you're already doing), had helped me a lot with fatigue, and I'm younger than you.

Exercise is also helpful, even though it feels impossible when you're already fatigued, but it truly does help.

Thank you that is massively helpful.

As some with ME, I sympathise. I have had some success with co enzyme q10. Supports mitochondrial function. You are best buying it in the ubiqinol form rather than ubiqone, as the body then doesn’t need to do the work to convert it to energy. Nicotinamide riboside has also made a difference. The two took me from bed bound to being able to leave the house.

Thank you @Thisweirdone. I'm sorry you have ME. I will look at those two supplements, that degree of change would be really worthwhile for me.

electrolytes, berrocca boost and mitochondrial resuscitate are supplements that might help (or might just be expensive wee)

😊

If you don’t already, drink loads. I suffer from fatigue and even slight dehydration makes it so much worse.

If you have a gas boiler when did you last get it serviced? (Thinking about carbon monoxide).

I have a carbon monoxide detector so probably fine but will look into this, thank you. (It wouldn't affect just me though would it?)

Electrolytes OP. Only cost a few quid and make a difference especially in this heat!

How is your diet?