My brother's uni friend did. No-one knows how much she won, but she dropped out of uni, bought a huge house and land, horses etc and has never worked and is now happily married with children.
I also had a friend whose parents won a substantial sum and gave each of the children £2m.
My parents won over £100k on the pools about 20 years ago. My father was a bit miffed because the following week his numbers/choices would have been £1m, but it was a nice win nonetheless!