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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro 10 stone or more to lose - Thread 10

1000 replies

TheBroonOneAndTheWhiteOne · 29/11/2025 12:34

Well, some of us are new, some of us are nearly at our goal weight and the rest are still in the trenches.

Everyone is welcome here. This is a safe and supportive space for people with a lot of weight to lose.

OP posts:
Thread gallery
34
MummyInTheNecropolis · 02/01/2026 21:10

I started C25K in May and struggled to get through the 1 minute runs, I never thought I’d ever be able to run for 30 minutes but the programme really works! I finished it in August and have carried on running 2-3 times a week: I do parkrun every Saturday, I’m not fast (only just got down to under 40 mins!) but I’ve never been last and I enjoy it so much. I’m not going tomorrow because of the ice and I’m gutted to be missing it!

RenegadeKeeblerElf · 03/01/2026 09:29

Back on track with a 1.9kg loss, so that's everything I'd put on over the previous two weeks plus another kg! Really enjoying 5mg, I've got the right amount of suppression back, although it did wear off towards the end of the week. And for the couch to 5k gang, I went out for a fab run this morning - just around the streets as all the local parkruns were cancelled but it felt amazing, I love running when it's crisp and cold but sunny!

SW 139.7kg

W1 -3.8
W2 -1.9
W3 -1.7
W4 -0.9
W5 -1.5
W6 no change
W7 -2.3
W8 -1.2
W9 -1.3
W10 -0.3
W11 -2.0
W12 -0.6
W13 +0.7
W14 -1.1
W15 -1.6
W16 -1.5
W17 -1.0
W18 -0.9
W19 -1.0
W20 -0.4
W21 -0.2
W22 -2.1
W33 +0.1
W34 +0.7 (Xmas)
W35 -1.9

CW 111.9kg, 27.8kg lost in 25 weeks

Mum2Fergus · 03/01/2026 10:22

Wk45 weigh in this morning (wk13 on 7.5mgs) … 2lbs down so back to pre Christmas break weight. Talk to me about C25K. I had the app many years ago (but didn’t do anything about it…doh!). I’m a long way off being a runner in my head…is it something I could start off on a treadmill and aim to progress from there?

SW (15 Feb 25): 19st 9lbs / BMI 44.4 (obese class 3)
CW: 14st 5lbs / BMI 32.8 obese class 1)
GW: healthy BMI (between 18.5 and 24.9 (8.3st-11st) for my height) - 3st 5lbsto go to get to top of healthy range. Targeting reaching that by my birthday in October.

I’ve lost 27% of my starting weight and averaging 1.6lbs loss per week over the 44 weeks.

Wks 1-4 (2.5mg): -17lbs
Wks 5-8 (2.5mg): -6lbs
Wks 9-12 (2.5mg): -11lbs
Wks 13-16 (5mg): -7lbs
Wks 17-20 (5mg): -4lbs
Wks 21-24 (5mg): -7lbs
Wks 25-28 (5mg): -7lbs
Wks 29-32 (5mg): -4lbs
Wks 33-36 (7.5mg): -5lbs
Wks 37-40 (7.5mg): -4lbs
Wks 41-44 (7.5mg): -0lbs
Wk45 (7.5mg): -2lbs

Total loss: 74lbs (5st 4lbs)

SilenceInside · 03/01/2026 10:29

@Mum2Fergus I did the C25K entirely on my treadmill so I’d say yes you can start there and see how you go. It starts off being a lot of very short bits of running with walking in between, which I found a good way to start. I would have found running non stop to be too much at the start. And you can repeat weeks or runs if the next step is too much.

Mum2Fergus · 03/01/2026 10:32

SilenceInside · 03/01/2026 10:29

@Mum2Fergus I did the C25K entirely on my treadmill so I’d say yes you can start there and see how you go. It starts off being a lot of very short bits of running with walking in between, which I found a good way to start. I would have found running non stop to be too much at the start. And you can repeat weeks or runs if the next step is too much.

Sounds perfect 😍 DS has a gym membership that allows him to bring a guest so it would be a way of giving it ago without any financial commitment (except trainers!).

Iwouldratherbesinging · 03/01/2026 14:49

Belated happy new year to you all, I’ve made a coffee and caught up with all the news.
unlike last year I wasn’t terrified of all the food over Christmas and at my last weigh-in on Tuesday I had maintained my weight which is a win in my books, the real test comes on my next Tuesday weigh-in as I haven’t fasted at all over the Christmas period.

I hit the sales after Boxing Day and bought 3 size 12 skirts and a size 14 jumper so I’ve dropped pretty quickly from a size 14/16 to a 12/14 and it feels so good!

I always said that I was going to swap to Wegovy after December but I’m too scared to, so I’ve ordered a 10mg pen, I’ve just started a new 15mg pen but have taken a 12.5 mg dose from it to see how I go, I’d like to titrate down very slowly but I’m also very nervous.

2025 was a good year, I’m happy, confident and not starting a new year hating my 20 stone+ body but embracing my 10 stone 10lb self instead, it’s so freeing.

congratulations on getting on the bmi chart @52soon, it feels so good! Also congratulations to @canaritini on your 30kg off! That’s such a huge difference in your photos, you look fab 🎉 and to @Onenotsosmallstep with the second c25k run! I’ve always said that I’ll start it in 2025, yet here we are in 2026 and I still haven’t started!

so sorry for your loss @Mum2Fergus, such a challenging time and a horrible shock for you all 😔

Fffreeeeezing · 03/01/2026 17:23

Week 42 and 1lb off for me today bringing me to a nice round 7 st 7lb total loss. Only 2lb off being in the 17's which will be mentally good, feels like I've been in the 18's for ages (it isn't ages, just feels like it!)

Not even slightly tempted to join all you lot in the C25K, me and running are not friends!
I have done a strength and Pilates workout today though and have just got in from a 6k+ walk with the dog, we are both now curled up under a heated blanket as I am beyond cold!

PearlTeapot · 03/01/2026 18:41

I applaud all of the C2Ks, for me with my lipo just managing to walk is a massive life changer for me so I'm happy but I would like to walk to 5k. I might make that my new years resolution.

@Iwouldratherbesinging buying those clothes must have felt so so good!

TragicMuse · 03/01/2026 19:11

I didn’t get a chance to weigh this morning but so far I have maintained over the last 2 weeks which feels really good. I’ve had everything I’ve wanted, haven’t counted calories at all and it just felt normal. Ate food, stopped when I’d had enough, didn’t overdo it but also didn’t feel all diet-y and cheated of nice things.

It’s a great place to be, mentally.

TheZingyFish · 03/01/2026 20:11

Last night at my mother’s house, will be home tomorrow, we’ve eaten rubbish. Not quite in the quantities I would usually as I’ve still jabbed, but nevertheless rubbish. I’m actually quite looking forward to eating normally again. I haven’t been near the scales since the 15th, so have no idea how much I’ve put on but I’m not actually bothered as I know I can lose anything I’ve put on as I have faith in the MJ.

I’ve seen a few people over the break and it has really opened my eyes to clothes. I’m thinking about what clothes actually suit as opposed to what I can get into for once, feels very strange but quite daunting at the same time in some ways.

I think my priority is to get fitter this early. My reasons for starting MJ were to be healthier, and that means being fitter and stronger, I needed to lose a chunk of weight before I could consider exercising. I’ve been really inspired by everyone embarking on exercise journeys and so this is how I want to follow everyone now. I can actually see a chance that I may get to where I want to be this year.

RenegadeKeeblerElf · 04/01/2026 09:15

PearlTeapot · 03/01/2026 18:41

I applaud all of the C2Ks, for me with my lipo just managing to walk is a massive life changer for me so I'm happy but I would like to walk to 5k. I might make that my new years resolution.

@Iwouldratherbesinging buying those clothes must have felt so so good!

That's a brilliant resolution. It's all about achievable goals, and doing what works for you rather than comparing yourself to others. For the longest time I had my step goal set as 10,000 as that's just the default, but I was hardly ever hitting it and so it was pointless having a target. Now my goal is 5,000 which doesn't sound a lot but is high enough to require some effort to achieve (I have a very sedentary job) but low enough to be achievable. As a result I'm probably doing more steps overall than I was when my target was 10,000 as I make the effort to walk to the swimming pool rather than drive so that I can get my steps in.

Doggymummar · 04/01/2026 11:31

RenegadeKeeblerElf · 04/01/2026 09:15

That's a brilliant resolution. It's all about achievable goals, and doing what works for you rather than comparing yourself to others. For the longest time I had my step goal set as 10,000 as that's just the default, but I was hardly ever hitting it and so it was pointless having a target. Now my goal is 5,000 which doesn't sound a lot but is high enough to require some effort to achieve (I have a very sedentary job) but low enough to be achievable. As a result I'm probably doing more steps overall than I was when my target was 10,000 as I make the effort to walk to the swimming pool rather than drive so that I can get my steps in.

Agree re achievable goals. It's demotealising to have a goal you never hit. I'll be back on the jabs tomorrow I think, still very suppressed but it's been two weeks I doubt it's going to get any less.

TragicMuse · 04/01/2026 12:07

Week 45, 7.5mg

SW 19st 4lbs (Jan 2025, pre-MJ)
SW on MJ 18st 11.5lbs (1 Mar 2025)
CW 13st 6lbs
Change this week 0
Total loss 82lbs

I’ve maintained for 2 weeks which is satisfactory!

I’ve switched to jabbing 7.5mg every 5 days and that’s working well for me. I feel suppressed but not nauseous. And I’ve changed the default days in my Shotsy.

Back to the normal now but with renewed vigour and the knowledge that I can do this.

I’m also pondering exercise. I hate exercise for its own sake but I’m ok if it’s a byproduct of, say, going to work or something. Either cycling or running will do as those are the only things in that category which I like. I hate the gym and won’t pay money for it. Swimming is ok but boring.

I have a bike and all my old running kit. So I’ll probably do that.

I won’t do my local parkrun, it’s repeated loops round the park and that’s another thing I hate! I did it once and some twat shouted what he thought was encouragement, but I perceived as him being a twat. So that and the repeated loops put me right off!

When I run I just start small and make my route bigger as I improve. That way I can’t duck out before it’s done, I still have to get home! I think there’s a single route parkrun near me, I’ll look into it. But I’m not doing 3 times round the park, that sucks!

AlicesMum2025 · 04/01/2026 12:20

Happy new year everyone. Just popping in to share that I achieved my big weight loss goal for 2025. Sort of. I wanted to lose 40.3kg by 31st December but, with the water retention caused by more salt and carbs over Xmas than usual, I missed the date, achieving it on 2nd January instead. But I'm ticking it off as achieved regardless 😁What's 2 days in the grand scheme of things.

I gained quite a bit 25th-28th December but I knew it was water not fat, so I just got back to eating my normal way and by 2nd it had all dropped off, plus a bit more to boot. Obviously very happy with that.

Total weight loss since start of May is now 40.7kg (90lbs / 6st 6lbs). November/December was a significant time for my weight loss, with several goals ticked off in short succession: 25% starting body weight lost, BMI <40 (on the chart), 50% of total target loss achieved, and <100kg. I need to sort out some more interim targets now though; I was so focused on <100kg that I didn't really think beyond that.

I've never told anyone my starting weight before but I've decided to be brave because I know you'll not judge me.

SW: 140.3kg BMI 54.1 (22st 1.5lb)
CW: 99.6kg BMI 38.4 (15st 9.5lb)
GW: 60.0kg BMI 23.1 (9st 6lb)

flipent · 04/01/2026 12:34

@AlicesMum2025 That’s done amazing numbers! Well done on all the achievements.

Lots of positives from many people over Christmas. If anyone didn’t have the same experience, that’s ok too. It is a long journey we are all on.

user593 · 04/01/2026 12:39

@AlicesMum2025 Congrarulations! It must feel nice to be under 100kg. I have a very similar SW and GW to you, I expect we’re a similar height, but I’m 7 months behind you (started end November). I hope I do as well as you have!

Iwouldratherbesinging · 04/01/2026 15:23

I’ve been on Mounjaro for 15 months and I’ve had my first experience of sulphur burps! You all have my utmost sympathy 😢

amazing numbers @AlicesMum2025!

Anotherstressedmother · 04/01/2026 16:11

I worked out my BMI today and it's 32 ..to get to 25 I need to loose another 4 stone
I started at BMI 56 .
Another 4 stone feels ok ..it feels doable
Hopefully by the summer I'm there
Although my mental health is derailing things currently
Am on day 5 of escitalopram..and I'm struggling with the side effects..
If by any chance anyone on here has experience of this medication I'd be glad to know how long it takes to work ,and when the side effects go

mamabeeboo · 04/01/2026 19:57

Hi losers! My official Christmas fat weight gain, without the water, salt etc is 2lbs!!!!! I'm so pleased and I'm absolutely taking that to the bank. 😌

Congrats to all those who are braving the bitter cold and doing C25k! I started it myself back in Sept. I'm comfortably doing 4k in 30 mins,but have been doing indoor exercise since November. Plan to go for my next run probably during Feb, estimating a big improvement as I'd be around 2 stone less than my last run.

I remember very clearly being the last person to finish the park run back in 2019 at 138kg. What made me suddenly go to park run from absolutely no exercise is beyond me, but I hated every second of it and never went back. Oh how times have changed!!!

@SilenceInside school and work starts on Tuesday and I'm desperate to get my routine back, just like you said. It's interesting how much we rely on routine to be on track.

@Iwouldratherbesinging brilliant news on the shopping and dress sizes! Can I ask what was your weight difference between your size 12s,14s and 16s? You said that the dress sizes seemed to change quickly?
Im just really looking forward to it myself. I've been a size 18-20 for about 3 stone. 🙄

Hope everyone is having a great start to the year.

PearlTeapot · 04/01/2026 21:37

@AlicesMum2025 we have similar numbers! I started a year before you though (without mj) so it's taken me a long time to go from 22.3 to ... 100.2kg WHEN WILL I SEE THAT 99! Every Sunday morning it tortures me!

Can someone help please, is there another dose in here? (well 40 clicks) with a pen needle or are we thinking not? I have my next pen waiting but it seems like such a lot to waste if not another dose in there.

Thanks

Mounjaro 10 stone or more to lose - Thread 10
Doggymummar · 04/01/2026 22:10

At least one dose yes, its usually a hefty dose left in mine

RenegadeKeeblerElf · 04/01/2026 22:50

PearlTeapot · 04/01/2026 21:37

@AlicesMum2025 we have similar numbers! I started a year before you though (without mj) so it's taken me a long time to go from 22.3 to ... 100.2kg WHEN WILL I SEE THAT 99! Every Sunday morning it tortures me!

Can someone help please, is there another dose in here? (well 40 clicks) with a pen needle or are we thinking not? I have my next pen waiting but it seems like such a lot to waste if not another dose in there.

Thanks

To me it looks like it's at the end of the 'regular' doses with only the bonus dose left. Given that you can't use syringes I'd say you might struggle to get 40 clicks out of it, although it partly depends how many clicks you've been using for priming. Can you try the 40 clicks and then move on to the new pen if it doesn't work?

RenegadeKeeblerElf · 04/01/2026 22:51

mamabeeboo · 04/01/2026 19:57

Hi losers! My official Christmas fat weight gain, without the water, salt etc is 2lbs!!!!! I'm so pleased and I'm absolutely taking that to the bank. 😌

Congrats to all those who are braving the bitter cold and doing C25k! I started it myself back in Sept. I'm comfortably doing 4k in 30 mins,but have been doing indoor exercise since November. Plan to go for my next run probably during Feb, estimating a big improvement as I'd be around 2 stone less than my last run.

I remember very clearly being the last person to finish the park run back in 2019 at 138kg. What made me suddenly go to park run from absolutely no exercise is beyond me, but I hated every second of it and never went back. Oh how times have changed!!!

@SilenceInside school and work starts on Tuesday and I'm desperate to get my routine back, just like you said. It's interesting how much we rely on routine to be on track.

@Iwouldratherbesinging brilliant news on the shopping and dress sizes! Can I ask what was your weight difference between your size 12s,14s and 16s? You said that the dress sizes seemed to change quickly?
Im just really looking forward to it myself. I've been a size 18-20 for about 3 stone. 🙄

Hope everyone is having a great start to the year.

Oh I love running in the cold! Especially on crisp, frosty mornings. I get warm quickly from the exercise and it's often nicer than running in the heat.

eibbed999 · 05/01/2026 08:35

Hi there people - finally forced myself onto the scales this morning. On Dec 18 (last weigh in) I was 237lbs. Today I am 252lbs. Over a stone. It's not unexpected, and I know (hope!!) that I'll be able to shift it relatively quickly, but I am also feeling a wee bit devastated. Not by the gain (deserved), but by the fact that the 'old me' hijacked the 'new me', and I've spent the last week joylessly stuffing my face with everything I could lay my hands on - not even really enjoying it, unlike the first few days of Christmas festivities, which were pleasant. This wasn't sociable or family time, this was sitting alone binging on pannetone and cramming multi-packs of crisps down my gob. It was waiting until everyone else was out and ordering a secret KFC and eating enough to feed four normal people. It was chowing down a whole box of After Eights and hiding the wrappers. NOT fun. I'm sure all of you know exactly what I'm talking about - the shame, the self-loathing, the desperation. None of which I've really felt since being on MJ. In the early days, there is no way I could have done this - physically and mentally, I was switched off from food in a way that was incredibly liberating. Now, despite increasing my dose, I've realised that my stupid brain is even more powerful than the drugs - I've gone and done what i thought back when I started MJ would be impossible. I've sabotaged myself, something I'm very good at. Sorry to bleat on, but this is one of the few places I can be honest.

I can feel the gain in my body and in the fit of my clothes, but more importantly I feel it in my mind. Now, I know, the mission is to get back on track - to shed all the excuses, and also to not give in to the self recrimination and self hatred, because all that does is make you feel worse and encourage you to give up on yourself. I hate being back at this point, feeling like I'm useless and a failure, and I also know if I let this type of thinking take hold, next thing is I'll be eating away my tears and my sadness, and the whole vicious circle continues. So today, my friends, I will be firm but kind with myself - onwards, downwards, and hopefully with some grace. We're all much better at being kind to others than ourselves though aren't we?

Jab day today, going up to 12.5. The other issue playing on my mind really is the cost - I always justified the MJ expense through the amount I saved in takeaways/meals out etc, but recently I've been having both - all my cakes, very much eaten! The higher doses are soooooo expensive, I'm not sure how much longer I can pay this much. I might have to change to Wegovy - not sure if anyone has had any experience of that? For the time being I have a couple of pens in the fridge.

So, hard reset today. Thanks for listening my friends, and belated Happy New Year!

RenegadeKeeblerElf · 05/01/2026 08:44

Really interesting article on BBC News today about why it's so hard to lose weight. Not sure how relevant it is to your struggles @eibbed999 but at least you know you aren't alone. And you've taken the most important first step to turning it around by acknowledging it and deciding you want to change. Hopefully the step up in dose will be the boost you need to break the cycle.

https://www.bbc.co.uk/news/articles/c2084q9079po

A treated image showing a green apple next to a cupcake

Why some people really struggle to lose weight more than others

Thousands of genes that have an influence on weight, say experts - which means weight loss isn't a level playing field

https://www.bbc.co.uk/news/articles/c2084q9079po

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