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Feminism: Sex and gender discussions

Hormones: are doctors lying to women - or transwomen?

29 replies

HeirloomTomato · 04/06/2025 22:43

What are the real health risks of hormone therapy for transwomen? I'm asking on here because I can't get a clear answer on this from Google or any search engine so I came to the TERF reality-friendly world of mumsnet. Here's an example of what I got when I searched this up:

  • Cisgender women: HRT is used for menopausal symptom relief and is typically used for a limited duration and at a lower dose due to potential health risks, especially with long-term use and advancing age.
  • Transgender women: HRT is a life-affirming treatment to achieve a feminine hormonal profile, with an individualized approach based on benefits and risks, which are carefully monitored. There is no absolute age restriction for initiating HRT for trans women.

Is this just BS? As a woman in early menopause / perimenopause, it was hard to access HRT even on the lowest dose, and I got dire warnings about not taking HRT for too long, ideally not more than 5 years because of the risk of stroke, blood clots, breast cancer and so on, even though it is helping me a lot.

Yet transwomen seemingly can take hormones for life without any doctor raising objections. So do the risks of HRT not apply to transwomen or are doctors just being dishonest? Or are they being dishonest with biological women about the risks of HRT? Or is no-one being dishonest because the main difference is that transwomen do not have the same risk for cancer due to not having female sex organs?

TL:DR - I am confused by the strictness of HRT protocols for women in menopause compared to the willingness of doctors to prescribe hormone therapy for transwomen and disregard or minimize risks. Unless the risks are just different?

OP posts:
MelOfTheRoses · 04/06/2025 22:54

No idea - I remember an article about a 90 year old man being given 'gender affirming hormones'.

Hormone medications for women have long been considered with huge suspicion - look at the many cancer scares for contraceptive pills.

Comtesse · 04/06/2025 22:52

MIL is 81 and still taking HRT - they will have to rip it from her cold dead hands basically. I think NICE may have changed the recommendations recently about how long HRT should be taken for…..

DorothyStorm · 04/06/2025 22:52

I asked chatgpt:

Why Are Women Told HRT Can Be Dangerous Long-Term, but Trans-Identified Males Can Take It Long-Term?
This is a valid and often asked question, and it highlights how medical guidance can seem inconsistent depending on the context. The key differences lie in why HRT is used, the risk profiles, and how benefits are weighed against risks.

  1. Different Goals and Contexts of HRT
Women (typically postmenopausal)
  • HRT is prescribed primarily to relieve menopausal symptoms like hot flashes, sleep issues, mood swings, and bone loss.
  • Usually includes estrogen alone (if the woman has had a hysterectomy) or estrogen + progesterone (if she still has a uterus, to reduce cancer risk).
  • HRT is often recommended for short-term use, and doctors aim to use the lowest effective dose due to concerns about:
  • Increased risk of breast cancer
  • Blood clots
  • Stroke
  • Heart disease, particularly when started later in life
Trans-Identified Males (transgender women)
  • HRT is used as gender-affirming treatment, intended to create and maintain female secondary sex characteristics (e.g. breast development, fat redistribution, body hair reduction).
  • Typically includes estrogen, often with anti-androgens to suppress testosterone.
  • Treatment is usually lifelong, as stopping HRT would allow masculine traits to return.
  1. Risk Profiles Differ
  • Age Matters:
  • Women usually start HRT in their 50s or 60s, after menopause, when the body is naturally more prone to cardiovascular issues.
  • Trans-identified males often start HRT younger, which may reduce some age-related health risks (e.g., lower risk of blood clots or heart problems compared to older adults).
  • Organ Differences:
  • Women have a uterus and ovaries, which affects how hormones interact — for instance, estrogen alone can raise the risk of uterine cancer unless balanced with progesterone.
  • Trans-identified males do not have female reproductive organs, and may or may not have had surgery to remove testicles (orchiectomy), altering the hormonal balance and associated risks.
  • Cancer Risk:
  • The risk of breast cancer is higher in women using long-term HRT than in trans-identified males, though the latter still carry a higher risk than biological males not on HRT.
  • Prostate cancer is also a concern for trans-identified males, albeit lower due to testosterone suppression.
  1. Why Risk Is Weighed Differently
  • For women, HRT is viewed as optional symptom relief — so physicians often approach it cautiously, especially if there's a strong family or personal history of cancer or cardiovascular disease.
  • For trans-identified males, HRT is considered medically necessary for gender affirmation and mental health. The benefits are considered more fundamental to identity and well-being, and therefore, risks may be more acceptable in the context of informed consent.
  1. Medical Understanding Is Still Evolving
  • The 2002 Women’s Health Initiative study caused widespread concern about HRT risks in women, but subsequent research has found that many of those risks depend on age, health history, and timing.
  • Long-term studies on HRT in trans-identified males are still limited, but clinical protocols involve monitoring for risks like blood clots, stroke, and cancers.
Summary GroupPurpose of HRTTypical AgeCommon ConcernsDurationAttitude Toward Risk Women Menopause symptom relief 50+ Breast cancer, heart disease Usually short-term Risk-averse Trans-Identified Males Gender affirmation Often younger Blood clots, stroke, cancer Lifelong Risk accepted due to psychological/identity benefit
FinallyAMum · 04/06/2025 22:48

I have no idea but I’m interested to know the answer. Watching and hoping someone more knowledgeable comes along!