Bowel issues maybe tmi

I had similar to you for a while but luckily my (private) doctor took me seriously and after tests to rule out cancer she referred me on to an allergy and intolerance specialist. They very quickly identified three foods I was intolerant to which I hadn’t even realised I’d been eating. After a couple of months of avoiding them I was right as rain again.

Definitely worth looking into.

If you’re really concerned you could also try improving your diet first. You mention a high fat diet. That’s unlikely to be helpful in avoiding loose stools.

If you've had all the investigations then yes, it is likely it is IBS being this bad. If you had crohns or colitis, one of the colonosopies would have picked it up. It is possible the blood tests didn't pick up a more minor level intollerance of dairy or gluten, they aren't the most sensitive and you can get false negatives when you do actually react to dairy or gluten. Have you tried all the elimination diets? You could cut all lactose and switch to lactose free or non dairy versions of things like milk, yogurt and cheese for 6 weeks and see if you have any improvement, likewise you could eliminate gluten for a 6 week trial priod and see how that goes. Have you tried taking a good quality pro biotic on a regular basis? Reduced the ammount of fat and sugar in your diet and increased fibre and protein? High fat diets in particular can cause loose greasy stools. Do you take any medication/supplement like peppermint oil capsules or buscopan that help with spasms in the gut and ease bloating, gas etc?

I sympathise, i have IBS (due to OCD about germs and toilets can't do the stool sample or cope with the cleansing out phase for a colonoscopy so crohns/colitis not ruled out) and i am often sore and have blood from the skin being so dry and splitting from how much wiping is necessary from the frequent loose/soft stools. It is also alarming to be fine one minute then get the churning and sudden need to go NOW with no warning.

If you have tried all the above, then i'm not sure what else a doctor could realistically do, other than possibly another round of blood tests and a potential re referral, but with 2 negative colonoscopies already i think it unlikely they would offer a third.

Is there any food that gives you any kind of allergy type symptoms at all, like numbness, tingling, burning or itching of the lips, in the mouth or throat? Any kind of facial itch or rash or flushing? Could you try an antihistamine incase its actually a food you're having a mild allergic reaction to and your body is trying to clear it out?

You have got to remove diary and gluten for a time period to see if that helps improve things.

You could even follow an elimination diet where you carefully add in foods back in every few days to see how your body reacts. I followed The Plan by Lyn-Genet Recitas.

You do need to see the doctor but you also need to do the things you can for yourself.

As someone with IBS, yes, it can definitely be terrible and change your daily life. However, if your gut is telling you something is wrong, trust it. Tell your doctor to work with you to figure out a cause (and keep making a stink until they do).

It definitely sounds like it needs more investigation and not just a pot of cream.