@Happierthanhippos Yes, the risk of developing one of the serious side effects are very, very low - one in thousands, I believe. Whereas the risks of remaining obese are substantial.
I asked Google about the relative risk of obesity compared to healthy weight across a range of conditions. Here’s the answer
Heart attack 28%-50% higher
Stroke 1.5-2 times more likely
Type 2 diabetes 6-7 times more likely
Knee replacement twice as likely
Cancer - varies by type, 13 cancers have obesity as a risk factor, ranging between 1.1 to 1.8 times more likely in obese people
PMOS - couldn’t find a multiplier, but it is made a lot worse by obesity.
Overall, an obese person would be extremely lucky to swerve all of those, and many of us will get several of them in our time. Versus the potential for unpleasant mild side effects while taking them, which many of us won’t get anyway, and a tiny risk of something very serious.
Thats what any individual has to weigh up. Mind you, risks are very theoretical and all in the future. For many, including myself, the immediate impacts of severe obesity in terms of physical discomfort, impaired mobility, social barriers, limits on what you can do etc, make the small risk of serious side effects a no brainer.
Not so for people who only want to lose 10lb, which is why the licensing conditions are as they are. These are serious drugs, not intended for a bit of cosmetic improvement.