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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

April 2026 Mounjaro Starters thread 2

27 replies

NorthDevonBeachLover · 18/06/2026 20:33

Looks like our first thread is almost full so thought I'd start a new one and link it.
The one where we head into the summer feeling lighter and hopefully on the right path x

OP posts:
MrsPepperpotty · 18/06/2026 20:41

Checking in on the new thread - thanks @NorthDevonBeachLover!

NeedSleepNowPls · 18/06/2026 21:16

Thanks for adding the new thread @NorthDevonBeachLover! Hope everyone's doing well this week 😊 I have my next weigh in tomorrow and after a week of awful stomach side effects I'm hoping for more than my usual pound loss. But nsv is fitting into my size 14 jeans for the first time in ages, and they're not skin tight!

TFICoffeetime · 19/06/2026 00:56

Shows all our hard work and persistence that we've filled up the last one.😂
Everyone seems to be loosing well.
🤞🥰

pomegranatepie · 19/06/2026 09:04

Thank you for the new thread, and great to see everyone doing so well.

Due my 11th jab this weekend, and still not sure whether to keep going at 3.75 or go back down to 2.5. I am definitely feeling more fatigued at this dose, and strong suppression days 2-5 ( a bit too much really, it's tricky to eat much on those days, trying to prioritise protein and fibre but it's a struggle )

Week 1 loss 8lb
Week 2 loss just under 2lbs
Week 3 loss 2.5lbs
Week 4 loss 2lbs
Week 5 loss 1.5lbs
Week 6 loss 1lbs
Week 7 loss 2lbs
Week 8 loss 3.5lbs
Week 9 loss 2lbs
Week 10 loss just under 2lb

I had a clothes try on yesterday, and I am fitting back into my size 12 clothes, and starting to feel good about my body again. I actually have a waist! There have been a few tentative positive comments from people noticing (but my weight has fluctuated so much over the last few years I think people are wary of mentioning it!) at just under 2 stone lost I can really see it now though.

I started trying to lose weight in January at 13 stone 8lbs, and was 13 stone 2lbs when I started MJ. Current weight 11 stone 3lbs.
My BMI is now 24.7 and I set my target at 23. So still another 10lbs to lose, which feels like a lot. I think I will just see how I feel over the next few weeks and reassess.

My biggest challenge will be to maintain a healthy weight, I have never managed to do that for more than 5 months in the last few decades of trying to manage my weight, it inevitably piles back on. I really really don't want this to happen this time, so I need a plan as I am getting closer. Thinking of titrating down slowly with click counting, or spacing doses out to longer than a week in between jabs maybe?

NorthDevonBeachLover · 19/06/2026 09:12

Well after a decent loss of 3lb on 3.75mg last week this week has a disappointment of only 200g loss! To be honest I'm not actually noticing much more suppression than when I was on 2.5mg so wondering if I need to bite the bullet and do 5mg...

OP posts:
22sra · 19/06/2026 09:53

Thank you for the new thread!
I’ve had a couple of slow weeks but still a loss overall. My period came earlier in the week but was 5 days late, so I put it down to that.
Weight has been fluctuating, but thankfully since yesterday I’ve lost 0.7kg. That puts me up to 8.5kg loss so far since 26th April. And I’m finally under 80kg again which has been my first marker since starting!
I was around 78kg in September last year before I had surgery. So once I’m back to that I will feel better, then the real target of getting back to pre baby weight can begin.
I ordered another 2.5mg pen which is due today. So I’m glad I stuck with that. I checked online and it said not to go up unless you have 4 weeks with no weight loss, which I haven’t had. Some slow weeks but still losing overall.
So many success stories! It’s so lovely to see! ☺️

22sra · 19/06/2026 09:57

@northdevonbeachlovertry not to worry, weight loss is not always linear. There are so many factors for women!
you will see from my readings below. Note there is no entry between 6th & 12th June or 13th & 18th June, and only 100g loss. That’s because in between those dates my weight actually went up!
As long as you have losses over a 4 week period you are still on track.

April 2026 Mounjaro Starters thread 2
pomegranatepie · 19/06/2026 15:40

I've got two and a half pens of 5mg in the fridge, and my next pen is due to come in a week so I went to cancel (with voy) as I expect to be well in target by the time I use what I have. They have offered to delay my next pen by 4 weeks, which I didn't realise was an option, so maybe a way to keep a maintenance dose going and save a little money?

DumpedByText · 19/06/2026 15:56

Hi everyone, I started in April, I'm doing 3.75mg and I've lost 23lbs.

I'm now 14st 2lbs, can I ask how many calories you're eating. I'm on 1300 but wondering if that's too many, trying prioritise protein.

pomegranatepie · 19/06/2026 16:40

DumpedByText · 19/06/2026 15:56

Hi everyone, I started in April, I'm doing 3.75mg and I've lost 23lbs.

I'm now 14st 2lbs, can I ask how many calories you're eating. I'm on 1300 but wondering if that's too many, trying prioritise protein.

I'm also on 3.75 (although think I might drop back down to 2.5) and not counting calories, I started to at the beginning, but I found it stressful and started obsessing too much. My suppression is quite strong though. I am just aiming to eat three balanced meals a day, protein and fibre focused. I try and add in a protein snack mid afternoon. A bit like mechanical eating, as on high suppression days I find it difficult to remember to eat.
This approach is working well for me so far! No idea how many calories that comes to, but I really want to break the cycle of dieting and gaining weight, and tracking just feels like another diet to me, which is what I wanted to avoid by taking the jab.
At the weekend I have a little more appetite, and I am trying to eat intuitively, which the mounjaro helps with, for example if I fancy an ice cream with my son I have some, but don't seem to want more than a small portion.

ElvisandAngel · 19/06/2026 18:12

Thank you for new thread.

I had my 9th injection today. 4 x 2.5mg and 5 x 3.75g.

I have lost 21lbs.

Apart from my husband nobody has said anything, but I do have a way to go.

I can feel and see the weight loss and my clothes feel so much better.

I do not count calories either anymore. I just eat really carefully and my job keeps me busy.

good suppression still on 3.75mg even after 4 weeks so I am going to carry on like this.

MyGardenDaisies · 19/06/2026 21:34

Hi!

I was up 0.9kg after my holiday on Monday. Today was -0.6kg since before it, so I’ve very quickly lost 1.5kg of water weight likely.

I’m eating much more this week though, and suppression doesn’t feel as strong. I think I moved the pen too much in and out of the fridge whilst on holiday and moving between accommodations, and it may have been exposed to warmer temperatures 🙄 no idea if there’s any science behind it, it might just be lack of sleep this week or moving more, but glad I only have 2 more doses of this particular pen left.

Overall I am losing weight so that’s good, just want to keep my pace as it was

custardlover · 19/06/2026 23:00

11th jab today, the second at 3.75. I lost 4lbs on 3.75 and not a bit of side effects! So pleased!

Thesehills · 20/06/2026 06:24

Hey Everyone,

Thank you for the new thread.

Week eleven jab and tenth weigh in today.

Week 1 - 7lbs
Week 2 - 2lbs
Week 3 - 2lbs
Week 4 - 2lbs
Week 5 - 1lb
Week 6 - 1lb
Week 7 - 2lb (first 3.75 dose this week)
Week 8 - 3lb
Week 9 - 2lb
Week 10 - 0lb (maintained weight)

Starting weight: 15 stone 7lbs
Todays weight: 13 stone 13lbs

Maintained my weight this week. No differences from this week to my normal weeks. My body is readjusting I guess, which is a good thing.

Lots of positives from everyone, really well done. My positive for the week is that people are starting to notice I'm looking different. 😊

Enjoy the return of the warm weather, happy weekend.

likewhatyoudo · 20/06/2026 10:26

Lots of us seeing regular weekly weight loss around 2lb (just under 1kg).

If I’m not mistaken, that means approx 1000 cal deficit per day (1kg = 7700 cal).

NettleTea · 20/06/2026 11:52

hello all. nice to see the new thread, and peoples continued losses. my weigh in is tomorrow. I had quite a rough day yesterday but I went without food too long whilst working and being in the sun, and flaked out. No headach at least so I wasnt dehydrated, I think my blood sugars crashed and that probably isnt a wise choice.

NettleTea · 21/06/2026 08:37

another 0.5 kg loss this morning, which puts me at 9.4 kg which is nearly 1 1/2 stone gone in 8 weeks.

looking at photos from the exhibition opening yesterday it isnt very visible yet, but I can feel it, and this is the lowest Ive been for a long time

Relaxd · 21/06/2026 14:21

Hi everyone,

Delighted to see many of us still going strong! Congratulations.

I have lost 2 stone and 5 pounds in ten weeks. I can’t quite believe it. I must have looked dreadful before! Current dose is 3.5mg, every 8 days which seems to help both energy and nausea. I take anti sickness tablets from day 2 to 4. From assuming I would only use WLI for a few months, I’m now planning for at least another 6 months then maintenance once healthy BMI. I fit better into my clothes and I’ve had a few positive comments. I can no longer stomach too many sweet foods. Not a bad thing! I travel a lot and have got the hand of using Frio cold pouches (which I highly recommend).

Start 94kg
Week 1 loss 4kg 90
Week 2 loss 2kg 88
Week 3 loss 2kg 86
Week 4 loss 2kg 85
Week 5 loss 1kg 84
Week 6 loss 0 kg 82
Week 7 loss 1 kg 81 changed dose from 2.5 to 3
Week 8 loss 0 kg 81 changed dose to 3.5
Week 9 loss 1kg 80 taken on day 8
Week 10 loss 1 kg 79 taken on day 8

MyGardenDaisies · 21/06/2026 19:26

Well done everyone!

my current stats are 10.2kg in 10 weeks.

I have decided to stay on 5mg for weeks 11-16. Then I have a 2.5mg pen lined up. However, I worry the suppression might be insufficient and require lots of work from myself during PMS time. Might stay on 5mg a bit more.

MyGardenDaisies · 22/06/2026 11:21

Hi!

-10.5kg in 10 weeks.Just took the 11th jab. How time flies!

starting weight 135.7kg
current weight 125.2kg
Goal weight 95kg

Last week lost 1.6kg, which is more than my average, but also included some holiday water retention.

EducatingEater · 22/06/2026 23:37

1 stone 10lb so far since April the 8th. I'm drifting a little and not keeping an eye on what I'm eatingx though still remaining under calories. Need to be more considerate of what is going in and also up the fluids. And protein. Struggling in the weather and with a lot going on but I'll get there

Well done all!

ilovemybluesharpie · 23/06/2026 09:24

4th week with no loss. Very disheartening. I have the phone call with my nurse on Weds, so going up to 7.5 and hoping that it kickstarts it.

Maybe 1400 calories a day is too much but I have been feeling hungry if I don't eat that many. According to the fitbit, the daily consumed calories is usually around 2000

I haven't put any more on though, have maintained, so it is obviously working but just not as well as it did initially.

NettleTea · 23/06/2026 09:42

Im interested in how the process works tbh, as we are always told 'calories in / calories burned' and that if you dont lose weight its "because you are eating too much", and yet this shows that there are far more complexities to that simple equation than just that. Im currently on 1200 calories of fresh ingredient only home cooked food a day - tracking and weighing just about everything, and yes, the GLP is stopping me feeling hungry but according to the 'its just what you are putting in your body' proponents, we should all be dropping weight like flies.

So many years of smug people like that who imply that you are secretly stuffing your face with big macs and cake that you conveniently 'forget' to log or you are lying, because they are lucky enough to not have levels of underlying complications that seem to really impact how your body works.

Things like stress hormones, lack of sleep, hormones in general, inflammatory conditions, thyroid or other glandular problems, auto immune stuff - fat accumulation issues like lymph or lipodema - and now even research that shows that during starvation and famine, women survive, because their bodies adapt to running on zero food - all this stuff impacts and alters that simple 'food in- calories out' trope.

What is it that makes 5mg or 7.5 mg more effective? is it just that the hunger goes away because Im on 2.5 and Im not hungry. and the calories in are not going to change, so is it doing something else too.

My focus is reducing inflammation, although obviously I want to lose weight too, as every lb off is better for my lymphodema, and as the anti inflammatory bit will be higher too in a higher dose, so Im unsure what its doing that people are suddenly going up a dose and losing weight again - is it because when the food noise returns that they ARE eating more? or is it more than that.
And if it is your body adjusting to lower calories, then, like intermittant fasting, is it worth a 'feast' to fool your body into a higher level is normal, just to then drop down again.
Im not quite sure what Im getting at here, just pondering really.

NorthDevonBeachLover · 23/06/2026 10:01

Some great pondering there! You raise some interesting points. Food for thought (pardon the pun)
Anyone else struggling with appetite in the heat?

OP posts:
MyGardenDaisies · 23/06/2026 12:26

I ate a lot yesterday, was feeling very hungry and ate even above maintenance, and today hit a new lower weight, -0.5kg off since yesterday.

I think sometimes there’s no weight loss even with deficit calories as a body fights back prolonged weight loss and holds on to fluids etc.

i would say weight loss is generally energy in/ energy out, but there’s sleep,water, hormones, inflammation, digestion, etc., that make it take longer sometimes to see it