Mounjaro -10 stone or more to lose - Thread 11

[TheBroonOneAndTheWhiteOne]

Thread 11?

How did we get to this point?

Ah well. We're doing so well. Do join us.

I wondered if anyone else has seen this recent bit of research into real-world weight regain after stopping GLP1s?

https://nference.com/publications/aWZ1vBEAAB8AP7-A/What-happens-to-weight-after-we-stop-prescribing-GLP-1-therapies

article about the research:

https://www.reuters.com/business/healthcare-pharmaceuticals/many-patients-may-keep-off-lost-pounds-after-stopping-glp-1-us-data-suggests-2026-01-22/

The headline is that the majority of people either kept the weight off or lost a bit more, about two thirds altogether. The remaining third gained some weight back. The research found that people who had been given some "exercise counselling", which I think means being told that exercise is a good idea and to do some, were more likely to keep the weight off. Those given diet counselling were no more or less likely to keep the weight off. So the implication is that exercise might be key to keeping the weight off.

There are plenty of weaknesses to this, it was an AI analysis of US patient records and there's lots of things that aren't considered in the data. But I thought it was interestingly hopefully compared to all the doom there is around weight regain after stopping taking GLP1s.

It definitely makes sense to me that exercise is the key thing - not only does the actual exercise burn calories but regular exercise and good muscle mass improves your metabolism and ensures you are burning more calories between exercises as well. It doesn't help as much for weight loss, but for maintenance I can absolutely see the importance. That's why I'm trying to get into a good routine with exercise now, so that it is ingrained as a habit by the time I want to move from loss to maintenance

Yes, I am very glad that I started C25K and managed to complete it, as now I know I can run on the treadmill and exercise every day if I want or need to. Even after a couple of weeks of not managing to exercise, I can still run non-stop for 30 mins plus, which is amazing to me. I know that I need to keep that level of activity up in order to help with maintaining.

Fell off the thread for a while as I wasn’t paying attention and didn’t realise we were on Thread 11 😅

I’m now 8.5 weeks in and 2st 12lbs down. The weight loss has slowed down a lot but despite that I feel like I can feel/ see the weight loss more. I bought some jeans at the beginning of the month and I think I already need to buy a size down 🥳

I’m still on 3.25mg but I think I’m going to move up to 5mg on my next pen. Psyllium husk capsules has really helped the last few days and hoping for a whoosh soon.

Advice needed
CLICKS
my friend tells me I can half my current bill for my 2.5mg for MJ by buying 5mg pen (found one priced at the same price as the £210 I’m paying for my 2.5mg pen) and he said “just counting clicks” for 2.5 and storing in fridge for 8 weeks as it will last 8 weeks
has anyone done this ?

Love that

looking forward to it

Yes @SilenceInside, I read it out loud to dh yesterday and we both said this is so much more encouraging than all the recent doom and gloom which is getting us all down/frustrated.

Yes, I do get the highest dose pen I can and dose myself by counting the clicks.
There is a chart available that gives you the number of clicks you need. I am sure someone here will be able to post the link.
If you are taking 2.5mg from. 5mg pen you would do 30 clicks. It should last for 10 weeks too, if you use the extra in the pen. You would need to buy some sterile needles (not from Amazon) to administer the dose as you won't be provided with enough needles.
It's certainly way more cost effective.

Do remember though that you will need to re-order within 6 weeks each time. Even if the pen lasts longer so that the companies are happy to prescribe it.

my pharmacy sold me 2 years worth of needles big box with 100 in the box

found an excellent video on YouTube 👍👍

I have done similar. It's been fine. Of course I am speaking from my experience, not from medical expertise.

I use a 7.5mg pen for 3mg jabs. It's your own assessment to make on whether you're happy going over the expiry date, for me for cost reasons I am.

@recruitretain

Just about everyone gets a higher dose pen and uses it for longer.

I always use a needle and syringe to extract the dose I want. I've never counted clicks, but I think a lot of people do.

When MJ went seriously up in price, even those who had said they'd never use a pen for longer than 30 days changed their minds.

I think I've said this before (probably on this thread 🤣) but my cynical side thinks it suits Eli Lilly just FINE to tell everyone not to use an MJ pen for longer than 30 days, and not to use the bonus dose.

They've got so pissed off with everyone using the bonus dose that they've revamped the design of the pen, so it's going to be like a Wegovy pen, with no bonus dose whatsoever.

Bastards.

Others have already answered about counting clicks, but I would add that £210 is incredibly expensive for 2.5mg. Check out monj.co.uk and save yourself at least £50 per pen, probably more.

There are pharmacies on the Monj discount price list who are doing 2.5mg for just over £100 with a new customer discount. 5mg is around £125 with the same discount.

Yes, you're paying far more than you need to @recruitretain

Constantly amazed by how many people I know on the jabs, my auntie and cousin told me they were on ozempic (they live in Canada) tonight. My brother also admitted he's been on them for a few months- initially he said to help him shift his belly, but he's been amazed by how much they've helped him to cut down on his drinking. Which has shrunk his belly fast! However he is now off them so we'll see if he can maintain it, he only did 3 months.

My BMI is under 40!!!!! 🥳

I am so happy to achieve this, it's been a while since I could say that! 5mg is working so well for me, hopefully the effects will last a while longer, it just feels like magic. I've had a lot more comments this week about my loss too, it seems like it's become noticeable all of a sudden. I know some people don't like the comments but I love them! I've worked bloody hard to lose this weight and I want that to be recognised and celebrated!

SW 139.7kg
W1 -3.8
W2 -1.9
W3 -1.7
W4 -0.9
W5 -1.5
W6 no change
W7 -2.3
W8 -1.2
W9 -1.3
W10 -0.3
W11 -2.0
W12 -0.6
W13 +0.7
W14 -1.1
W15 -1.6
W16 -1.5
W17 -1.0
W18 -0.9
W19 -1.0
W20 -0.4
W21 -0.2
W22 -2.1
W23 +0.1
W24 +0.7 (Xmas)
W25 -1.9
W26 -0.7
W27 -1.8
W28 -1.3

CW 108.1kg, 31.6kg lost in 28 weeks

WARNING: I have come to whinge!!

I've been struck down with the bastard that is plantar fasciitis, a pretty bad episode that has also spread up the back of heel/Achilles area. I can barely walk. I have a trip to Chester planned with my daughter tomorrow and honestly don't think I'm going to be able to manage.

I've suffered with it on and off for maybe 30 years, so I know the drill - stretching, ice, various support socks, gel pads, insoles, Vionics, I am fully loaded. But it really, really pisses me off when it happens, because I can't walk - and walking is basically my sanity saver, especially after spending so long recovering from ankle surgery in 2024. I've not started driving again since the surgery (I am a giant wuss, plus we have a different car and I'm scared of it!) but not that bothered, I live in an area where I have everything I need, and I LOVE walking. But now, being stuck in the house, dependent on others, I feel so depressed - I know it will clear up, been here before, but I think I'm getting some kind of flashback PTSD type vibe to when I was in a wheelchair and having to use a commode! Obviously it's not that bad, but it's really upsetting me.

Every time you read about PF it says being overweight is one of the factors - like it seems to be for bloody everything, from cancer to heart disease to global warming - and I'd hoped that shedding 20% of my body weight would help. Aaaagh, I hate this!

Right. Whinge over. I am being a giant baby, I know, but needed to blow off some steam! As you were...

Official weigh in day for me. I’ve been hovering within 250g all week so not much changed since last weekend but I’ll proudly record this as a win and a milestone: I’m 30kg lighter than I was at the end of August! Next goal is to lose 2 more kg to reach 90kg.

Whinge away, PF sucks! Mine is mostly better now but still niggling so I feel for you with a flare up just when you have a nice day planned 😥

My sympathies @eibbed999! I’m permanently stuck in FitFlops now or else I get terrible PF.

Congrats @SnowWhiteisMyFavourite , that’s an amazing loss!

Thanks @user593 and @RenegadeKeeblerElf - it always sucks, but the timing is rotten. Tomorrow was a Christmas present, and involves a train journey, a bus journey, a show, and an overnight stay on the 2nd floor of a hotel in Chester! I've been so looking forward to it, a nice night with my daughter, but as at the moment I can't make it into the kitchen without crying it's not looking good! I might try with my crutches for a bit of a stability, and these really bad flare ups do sometimes clear within a few days - I guess I'll see how I feel in the morning. There just seems to be no rhyme or reason to it, you know - I've done nothing different, not changed shoes or walking routes, stuck to my 10k steps all week. I know its silly, but I also hate that it ruins the stats on my step tracking app!

eibbed999, i had plantar fasciitis so bad I ended up on crutches a few years ago.

Have you done any single leg gym machine exercises? It may help you isolate the specific muscle causing it, so you know where to focus building strength. It's usually not the affected foot/ankle.

I was a daily long distance runner. When PF stopped me running I changed to the gym and discovered via single leg presses that my left foot PF was caused by an exceptionally weak right calf muscle. I then spoke to the resident PT at the gym, who watched my on the treadmill and suggested I also had a tight left hip (can't remember the muscle name). Essentially he suggested what happened was:

• I damaged the left hip muscle
• This caused a change in running gait to compensate for the slight hip pain/niggle
• This changed gait put increases pressure on my right calf, due to an uneven running gait
• This resulted in another change in my running gait to compensate for this niggle
• All of which ended up outwardly showing as PF

Essentially, if I'd have properly rested and allowed my hip or calf niggles to heal, so that my running gait remained even, then I'd have not had PF.

I may be projecting, but you mentioned ankle surgery and lots of walking. It's possible that your walking gait is uneven due to your body compensating for weaker muscles following surgery, and this is the cause of repeated PF.

Or maybe you're not me and I should stop projecting!