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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Brand new January 2026 starters

1000 replies

BG2015 · 26/12/2025 11:58

Hi, my first WG pen is in the fridge ready to start on 1st January.

Im 56 (57 in Feb) post menopausal and cancer survivor in remission 5 years nearly. still taking cancer prevention medication that I believe that is hindering my weight loss. I just can't seem to lose it no matter how much I try. It took me 5 months to lose 10lb earlier on in the year.

Im 5' 8" so carry my extra weight well.
CW 13stone
TW 11 stone

Whose joining me on this weight loss journey?

OP posts:
Thread gallery
11
MrTiddlesTheCat · 16/01/2026 20:32

YouBelongWithMe · 16/01/2026 18:33

Day 1 here for me after injection last night. Feel like it must all be in my head because it can't have kicked in so well already.

Today I got up and made my coffee to take to work. Forgot to drink it until midmorning. Didn't drink it all.

Had a v small portion of chia+greek yoghurt with a pink lady apple at 12.30pm

Got an M&S individual meal in the oven which I'm looking forward to but not STARVING for.

Ate no sweets. No grazing in the car on the weekend treats I bought the kids.

😱

I was the same, it kicked in very fast. I only ate part of my breakfast just half an hour after my first injection.

CatNoBag · 16/01/2026 20:42

KeepPloddingOn4Ever · 16/01/2026 20:15

okay, thanks- sorry you were suffering too! I will pick some up tomorrow if nothing happens before then!

My system can be very sensitive to change too. Post operative prescription of Senokot has been a silver lining. Take at bedtime and drink plenty of water!

CatNoBag · 16/01/2026 20:49

My love of foods extends to learning all the ins and outs of nutrition, have been following this lady for a while and she’s just posted something that might be of interest to M&S shoppers!
www.instagram.com/p/DTk7wuQgiAL/?img_index=14&igsh=YWFtcjUzYTRsMHdj

bookwormcrazy · 16/01/2026 20:52

blackandwhitefluffycat · 16/01/2026 18:37

I googled last week as I’d been considering staying on 2.5 and it said that 2.5 wasn’t even classed as a therapeutic dose and is just to get your body used to it. I think MJ acts on more than just appetite (insulin resistance?), and as I’m battling the effects of HRT on me (weight gain!) I feel I need all the extra help I can get, especially after this week’s 0 loss even with the low number of calories that I ate each day. I’m also worried if I got another 2.5 it would lose effectiveness and I’d be stuck with it for weeks.

My husband went up to 5 despite losing lots on 2.5 and he has been dropping multiple lbs weekly consistently for a couple of months on 5 - he’s not going to go up any further than that.

I literally could have written this post myself - minus the husband on jabs as I really wanted to try and stay in 2.5 as long as possible.

however - after weighing myself halfway during week 2, I had gone up a lb. I’m going to try and hold off weighing again until jab du on Monday but the more I think about it, it’s a risk staying on 2.5 as I’m battling all sorts before starting. Peri meno (lots is weight gain), PCOS, endo. I don’t want to go up too high too quickly and would rather stay low and lose over a longer period but is it a risk ordering another 2.5 pen if I am going to stay the same for a month.

What’s the latest you can make a decision and order your new pen?

FrothyCothy · 16/01/2026 21:48

Not a very exemplary eating day today but I couldn’t finish the meal I picked up at an event tonight and still feel (almost uncomfortably) full 3 hours later. I definitely need to work on eating slower and paying attention to the “you’re full!” cues. Usually I’d have had a meal, and a big bag of maltesers or something so am relatively happy with my
restraint. Also did the cinema this week with no treats. Need to muster energy for the gym tomorrow to make it 3 sessions for the week - my body is reminding me that it was unwise to take a 4 month break from
exercise!

Whatstfpoint · 16/01/2026 22:09

I'm hoping to learn the difference between not needing to eat anymore and being full. I don't think being full is the goal. What a revelation. My friend said earlier that she's able to stop eating and push away the plate. Would never occur to me. It's my food and my portion so im going to finish it. How this has never occurred to me I don't know.

blackandwhitefluffycat · 16/01/2026 22:18

bookwormcrazy · 16/01/2026 20:52

I literally could have written this post myself - minus the husband on jabs as I really wanted to try and stay in 2.5 as long as possible.

however - after weighing myself halfway during week 2, I had gone up a lb. I’m going to try and hold off weighing again until jab du on Monday but the more I think about it, it’s a risk staying on 2.5 as I’m battling all sorts before starting. Peri meno (lots is weight gain), PCOS, endo. I don’t want to go up too high too quickly and would rather stay low and lose over a longer period but is it a risk ordering another 2.5 pen if I am going to stay the same for a month.

What’s the latest you can make a decision and order your new pen?

I think it can vary. My husband has had no issue ordering new pens, but when I placed my order I had an email saying there was a delay and it could take a few extra days. When I looked at reviews there were some people saying they had waited weeks! Luckily mine did turn up a couple of days later, but I wouldn’t want to leave it too late! I’ve checked my account and I can order now.

FrothyCothy · 16/01/2026 23:47

Whatstfpoint · 16/01/2026 22:09

I'm hoping to learn the difference between not needing to eat anymore and being full. I don't think being full is the goal. What a revelation. My friend said earlier that she's able to stop eating and push away the plate. Would never occur to me. It's my food and my portion so im going to finish it. How this has never occurred to me I don't know.

I felt weirdly proud of myself throwing a handful of chips in the bin this evening instead of forcing them down just to clear my plate!

Whatstfpoint · 16/01/2026 23:51

FrothyCothy · 16/01/2026 23:47

I felt weirdly proud of myself throwing a handful of chips in the bin this evening instead of forcing them down just to clear my plate!

That's fantastic!!

FrothyCothy · 16/01/2026 23:57

Whatstfpoint · 16/01/2026 23:51

That's fantastic!!

Well I probably should have done it a few chips earlier 😆

Whatstfpoint · 17/01/2026 00:20

FrothyCothy · 16/01/2026 23:57

Well I probably should have done it a few chips earlier 😆

It's the start of breaking a habit!!

Howmuchhowlong · 17/01/2026 08:31

Jab 2 this morning, I had help last week with the first one, so (silly as it sounds ) I am so pleased I did it myself. Weighed in and a 3lb loss which I'm delighted with. I definitely felt hungry last night and it took a lot to keep on track, which showed me how effective the suppression had been through the week.

mendandmakedo · 17/01/2026 09:00

6 pounds off today, end of first week.
10lb off since I started "diet" ecstatic with that. Second injection later today.

BooptotheFloof · 17/01/2026 09:08

End of week 2 - I have lost another 3lb - so that’s a stone in two weeks - 3 stone to go but for the first time ever that feels achievable.

I think that is my main realisation with taking MJ - that I can do this - I can finally get down to the weight I want to be and I’m no longer seeing it as an impossible goal

I’ve stood on the scales every day this week and everyday they have said a little bit less - if if it’s just a few ounces it’s less than the day before and it’s keeping me really motivated

I had a biscuit yesterday and the for the first time in years I didn’t feel guilty!

YouBelongWithMe · 17/01/2026 09:25

Well done everyone on their losses!!

I feel the same about portions - it's there and on my plate and will finish. Hoping this process helps to rewire what my portin should actually be, i e. Not the same size as my 6ft5 husband.

Etherealcelestialbeing · 17/01/2026 09:27

First jab finally done. I didn’t expect it to be delivered so quickly so was planning to start next week. But I’m glad to have begun the journey. I am worried about side effects as I tend to have a sensitive digestive system. Will see how it plays out this week.

Posting stats to keep myself accountable
Starting weight 13lb 6
Height 5 ft 2
BMI 34
Goal weight??? Due to my height, my healthy BMI would mean weighing under 8 stone! So I am going to try to lose and then assess where I feel is comfortable and realistic given I’m peri-menopausal and love food!

SucculentWindowLedge · 17/01/2026 09:29

Yesterday I started on 1.25 Mounjaro (30 clicks of 2.5 pen). I kept putting off taking 2.5 because I am so busy with work and family - I was terrified of losing time to symptoms, so compromised with myself.

I hope to lose a pound a week and will calorie count to make sure I get protein
and fiber.

I am not hungry and having to eat VERY slow today. Yesterday I ate 1200 calories (struggle to stay under 1700 on a normal diet). It could be placebo, but I’ll take it.

I’ll go up to the 2.5 next week if it doesn’t work for long this week, but I had to start. I am optimistic. I wish to lose 25 pounds.

glutenisthedevil · 17/01/2026 10:04

Weigh day for me today and I lost 2lb (8lb in 2 weeks) Third injection later tonight and I have the Pepto Bismol at the ready for day 2 this time!

Well done to everyone else on their losses.

intentionals · 17/01/2026 10:08

Etherealcelestialbeing · 17/01/2026 09:27

First jab finally done. I didn’t expect it to be delivered so quickly so was planning to start next week. But I’m glad to have begun the journey. I am worried about side effects as I tend to have a sensitive digestive system. Will see how it plays out this week.

Posting stats to keep myself accountable
Starting weight 13lb 6
Height 5 ft 2
BMI 34
Goal weight??? Due to my height, my healthy BMI would mean weighing under 8 stone! So I am going to try to lose and then assess where I feel is comfortable and realistic given I’m peri-menopausal and love food!

I am the same height! Also not sure if my goal weight - I feel like 8 stone was 18 year old me. I don’t know if the closer I get to it the more I will realise I had just lost sight of what healthy actually means for me?

Alltheyellowbirds · 17/01/2026 10:23

End of week one! Have lost 10 pounds 🥳

Weighed daily. First few days it gradually crept downwards. Then two days ago jumped up a couple of pounds, yesterday up a couple more, and I was starting to worry! But then it whooshed down six pounds overnight to lower than before. Good reminder not to panic when the scale jumps up for no reason and remember that’s it’s just water levels fluctuating.

Important thing is that the overall trend is DOWN.

Interested to see what happens this week. Imagine it will probably slow down a bit after the initial water weight is all off.

Alltheyellowbirds · 17/01/2026 10:29

SucculentWindowLedge · 17/01/2026 09:29

Yesterday I started on 1.25 Mounjaro (30 clicks of 2.5 pen). I kept putting off taking 2.5 because I am so busy with work and family - I was terrified of losing time to symptoms, so compromised with myself.

I hope to lose a pound a week and will calorie count to make sure I get protein
and fiber.

I am not hungry and having to eat VERY slow today. Yesterday I ate 1200 calories (struggle to stay under 1700 on a normal diet). It could be placebo, but I’ll take it.

I’ll go up to the 2.5 next week if it doesn’t work for long this week, but I had to start. I am optimistic. I wish to lose 25 pounds.

Edited

Good luck! If it helps I was also really worried about symptoms but didnt have any in my first week except indigestion once. Second jab yesterday and still feeling ok - long may that last 🤞

Etherealcelestialbeing · 17/01/2026 10:45

intentionals · 17/01/2026 10:08

I am the same height! Also not sure if my goal weight - I feel like 8 stone was 18 year old me. I don’t know if the closer I get to it the more I will realise I had just lost sight of what healthy actually means for me?

Yes I don’t think I’ve been a healthy weight since I went off to uni at 18 to be honest. I’ve felt too big for a long time. I have leaned into ‘acceptance’ and justified emotional eating as ‘being kind to myself’. I think tipping into size 18 clothes in the autumn has pushed me to take action.

Glad to be on the journey with you!

Concernedcatmum · 17/01/2026 11:38

Well done all on your losses!
I’ve been hibernating this week and full of cold so haven’t been doing any exercise (also think this is why exercise felt so grim last week if anyone saw that post!)
Realised I haven’t posted my stats.
A bit embarrassed to post my starting weight of 121.7 kg. Had some medical issues after having my first child and went on some meds that caused me to pile on weight. Then busy life and kids…just haven’t found time to prioritise myself. But 2026 is the year!
Jab 3 today and CW is 115.3 so down 6.4kg in 2 weeks.
Goal weight…for my height upper limit of a healthy BMI is 74kg so would love to aim for that, but it’s a long way to go.
Going away for a spa weekend with school friends in June and would love to feel healthier in myself and not embarrassed to be in a swimsuit.

YellowStockings · 17/01/2026 12:04

@Concernedcatmum that's a massive loss already, congratulations!

I started at 111 a few weeks ago and have a similar long term goal. That feels really far off though, so my first goal is I'd like to get to 100kg by mid-March (when I've got a 40th birthday party to go to), and then maybe 90-93kg by mid-May (when I've got a 60th to attend).

Whatstfpoint · 17/01/2026 12:20

FrothyCothy · 16/01/2026 23:57

Well I probably should have done it a few chips earlier 😆

Im following your example. I eat out Saturday at noon when running errands and my usual meal looked huge to me. I didn't manage it all and it's weirdly OK.

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