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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

September 2026 new starters thread?

273 replies

Tree2026 · 01/09/2026 13:05

Hi all, I cannot find a new starters thread for September 2026 (did my first mounjaro jab today) Is there one ?

OP posts:
Shedmistress · 21/09/2026 13:18

Frenchlady14 · 21/09/2026 08:40

Shedmistress Bonjour! Can I assume you are in France like me? My doctor sent me to an endocrinologist to try and bring my Cholesterol and tryglicerides down - also high blood pressure - plus pre-diabetes. It is called Metabolic sydrome and I need to bring my levels down. BMI 28 but with other problems she decided to prescribe MJ. Still v v expensive as there is no refund but I'm ok with that for the moment. Lots of diabetes in my family so I hope to be able to ward that off.

Had my first jab (nervously) yesterday afternoon and bam! Huge suppression after a couple of hours and am trying to sip tea this morning as am feeling a bit nauseous. Maybe try to eat some yoghurt in a bit but the thought is making me feel yuk :(

Oui I am!

I had to have a full panel of bloods done and send her the results last week before my doctor said 'yes' but she's had the pack on her desk the last 3 times I've been there so I knew she was on board with it as an option. she did not suggest it, I did.

Feeling much better today, hopefully learning not to eat large meals before a jab is the way to manage any sickness but yes, I have had virtually no hunger since starting.

Frenchlady14 · 21/09/2026 20:56

Shedmistress - Hi from the Dorodgne :)

I am so pleased to have found cottage cheese in Grand Frais - they don't sell it in the usual supermarkets - as you prob know - but there doesn't seem to be a great equivalent in France and it is so useful and high protein.

Managed some turkey breast and veg for lunch and a little bit more for tea with half a small pita bread which I actually didn't really want but thought I should as I do have a bit of a headache I think from not eating enough. Taking a psyllium husk capsule before bed with a large glass of water. Really pleased about the supression and I took mine on Sunday so hopefully will be able to have un verre de vin on Saturday without too much trouble - have to say though, I really wouldn't fancy one at the moment!

Slipperslopey · 22/09/2026 07:07

Weighing in one day early this week as I’m away tomorrow and won’t have scales.

1.7kg loss 🥳 really happy with that, I’ve found suppression much higher this week (week 3) so think it’s building in my system and I’m going to order another 2.5mg pen I think.

im preparing myself for a much smaller loss this week as I’m going away but happy so far.

total loss = 4.8kg
week 3

Shedmistress · 22/09/2026 07:31

@Frenchlady14 The Dordogne border is just south of where I am, it still feels weird when we 'pop to the Dordogne' to go to the market on the odd Wednesday morning that my French class doesn't run.

@PaolaGLP1Guide for me, my main issue was that someone had said 'make sure you have a decent meal before taking the first dose' and it was the worst thing possible. Preparation is key to being able to do this to minimise the side effects, is what I have gathered so far.

Frenchlady14 · 22/09/2026 08:15

@PaolaGLP1Guide

It was a bit the same for me as @Shedmistress said - I was very scared before my first jab as there is so much information around, it is difficult to sift through it - I really didn't want to overload my stomach with a big meal so I had a very small salad before my first jab and wasn't expecting the supression to be so strong straightaway - that meant I barely ate anything on Sunday at all - but I didn't have any side effects apart from that. I felt a bit sick on Monday morning and slightly queasy this morning. I don't think I am eating enough as I just don't want to :( My diet wasn't that bad before as I am taking it mostly for medical reasons, (and a bit of menopausal weight) but I am aware I need to up my calories a bit or it won't work properly.

Good luck with your guide but it is so subjective as people seem to react so differently.

After winding myself up for my first jab - it was surprisingly drama-free and easy so I won't worry about the next one.

InevitableDownwardSpiral · 22/09/2026 08:48

Just weighed and taken my fourth jab. A disappointing 0.6lb increase for me this week, though I'm trying to focus on the 6lb total loss instead.

I have to say I've been a little less on it this week, I've not been getting my steps in or drinking enough water. I do think the first two weeks I was definitely in 'diet mode', really focused, and also a little worried about eating something that would give me nasty side effects and this week I've probably relaxed a little.

I have to order my next pen this week and I think I'm going to stay on 2.5mg for now. I feel really good on it, and the urge to snack has completely gone which is great. I have been tracking my calories for the last three weeks and I know if I stick to my usual meals I average around 1500 a day. I think I'm going to stop tracking now though. I know that I can become a little obsessive about the numbers but I always crash and burn after a few weeks. It hasn't helped me in the past or I wouldn't be the weight I am now, so I'm going to try and relax and let the mounjaro do its thing.

Hello to all the new joiners and here's hoping we all keep moving in the right direction, however fast or slow we are moving 😊

Starting weight 194.4 lbs
Current weight 188.4 lbs
Week 1 -4lb
Week 2 -2.6lb
Week 3 +0.6lb
Total loss -6.0 lbs

InevitableDownwardSpiral · 22/09/2026 09:48

Also, does anyone’s pen look like this after jab 4?

September 2026 new starters thread?
Shedmistress · 22/09/2026 10:19

I believe that alot of the older pens had 5 doses in them so there are ways of getting that out, see the 'Golden Dose' thread.

Berengariaoftheverylowcountries · 22/09/2026 11:30

@InevitableDownwardSpiralyes mine does!

Iloveitalianfoodyum · 22/09/2026 11:46

Hi everyone thanks for posts to reply to me and I’m hearing that the preparation is key to reducing the side effects.

I have been reading up on what I can eat and it’s not a massive list - to me anyway. Most of my standard dinners I should avoid and other meals need to be very different. I eat with my children and cook a family meal usually pasta or home made pizza or a grilled quorn wrap (we are vegetarian) and I don’t know if that will work any more.

to be honest if I eat what I can comfortably tolerate while on the jabs I would lose weight anyway I’m pretty sure of that so honestly wondering whether just to try dieting again by calorie counting and not risking the jabs….

AdventuresOfSnufkin · 22/09/2026 11:50

InevitableDownwardSpiral · 22/09/2026 08:48

Just weighed and taken my fourth jab. A disappointing 0.6lb increase for me this week, though I'm trying to focus on the 6lb total loss instead.

I have to say I've been a little less on it this week, I've not been getting my steps in or drinking enough water. I do think the first two weeks I was definitely in 'diet mode', really focused, and also a little worried about eating something that would give me nasty side effects and this week I've probably relaxed a little.

I have to order my next pen this week and I think I'm going to stay on 2.5mg for now. I feel really good on it, and the urge to snack has completely gone which is great. I have been tracking my calories for the last three weeks and I know if I stick to my usual meals I average around 1500 a day. I think I'm going to stop tracking now though. I know that I can become a little obsessive about the numbers but I always crash and burn after a few weeks. It hasn't helped me in the past or I wouldn't be the weight I am now, so I'm going to try and relax and let the mounjaro do its thing.

Hello to all the new joiners and here's hoping we all keep moving in the right direction, however fast or slow we are moving 😊

Starting weight 194.4 lbs
Current weight 188.4 lbs
Week 1 -4lb
Week 2 -2.6lb
Week 3 +0.6lb
Total loss -6.0 lbs

Well done @InevitableDownwardSpiral and @Slipperslopey! I've just completed two weeks and am 6lbs down, starting weight 228lb. I'm also thinking of remaining on 2.5mg as I'm similar with no desire to snack and eating about 1400-1500 cals a day, 90g protein. I'm just about to start taking a collagen supplement to support my skin.

I'm really appreciating how it helps me to know when I've had enough- even when dinner is really good I'm not tempted by seconds. Now convinced naturally slim people are just operating with better levels of GLP1. I've been reading that they're studying people who respond well to 2.5mg to understand what's going on, one paper said that these people possible have lower baseline levels of GLP1 in their bodies so respond to even small new doses.

AxisofEvelKnievel · 22/09/2026 16:54

Shedmistress · 22/09/2026 10:19

I believe that alot of the older pens had 5 doses in them so there are ways of getting that out, see the 'Golden Dose' thread.

Have you got a link to the golden dose thread? I’m having trouble finding it.

MrsALambert · 22/09/2026 21:53

Second weigh in today and another 2.5lb off which I’m pleased about. Less noticeable suppression this week but as a PP said, I’m feeling really energetic.
week 1 -4.5lb
week 2 -2.5lb

I’m also in the ‘lot to loose’ camp with seven stone to go

Frenchlady14 · 23/09/2026 09:40

Ikg down today since Sunday evening - I am actually amazed !! It might well be water weight but it's nice to see. I find the suppression (with a little bit of nausea) highest in the mornings and by dinner time it is a bit easier.

I didn't sleep well though last night with some stomach cramps - but then I'm not sure if it's the medication as I've got a very sensitive stomach anyway - I have to be careful not to attribute my normal problems to the new way of eating.

Onwards and downwards I hope - going swimming today so I'll be able to see if I can do my usual amount of exercise as I can't eat anything this morning - hopefully will ease by lunchtime. I'm amazed to respond so strongly to 2.5 - it would be great if it continues and I don't need to go up :)

FMLpassthegin · 23/09/2026 12:13

Hi all,
Please may I join? I started on Sept 6th. I started with Wegovy and have one more jab left and then for my next batch I'm switching to Mounjaro.
I'm injecting every Monday so I've just used my third WG 0.25 and weighing in 'officially' on wednesdays.

SW Day Sept 6: 76.6kg (168.9 lbs)
Week 1 (Weds) Weigh in Sept 9: 75.9kg (167.3lbs)
Week 2 (Weds) Weigh in Sept 16th: 74.6kg (164.4lbs)
Week 3 (Weds) Weigh in Sept 34rd: 72.9kg (160.4 lbs)
GW 58-60kg (@130lbs).

Side effects / Experience so far:
Have been minimal. I've found weds/thurs is when I feel a bit 'blah' kind of hungover headache ish, or super mild nausea. I am not finding that I feel any different from food choices - i've been able to drink, eat sugary things or fatty things without feeling sick which I've heard is mean to happen but I've noticed the feeling fuller on smaller portions and definitely less cravings or 'food noise' around wanting to reach for sweet treats or to have an alcoholic drink. I've definitely cut down my drinking and snacking on quick fix cookies/sweets as a result which is was one of my main motivations for doing this.

My why.
Over the summer I noticed with the crazy heat I was exercising far less and tending to drink much more regularly - a glass of rose was becoming a kind of daily 'end of the day' marker and I didn't like that! I find summer school holidays (despite having grown up kids) really hard for maintaining routines and I'm relieved to be back to 'term time' and re establishing workout routines and healthier habits.

I'm AuDHD so I find I'm quite all or nothing with food. I can forget to eat and then suddenly be starving at the end of the day. The impulsive side and dopamine ADHD side of me can be prone to binge eating sugar and carbs and the Autististic part of me can then become quite over disciplined so I'm hoping this might help me establish a better balance with the dopamine rewards from sugar and alcohol etc being taken down by the GLP1.

I take stimulant meds but they haven't really had any impact on my appetite or cravings which I know can be a bonus side effect for some people - that being said I think I metabolise them really fast... I'm 5.6ft and have put on quite a bit of weight for me and I hate it so keen to get back into the 130's where my clothes feel better and I feel like I can sit comfortably a few pounds either side of around 130-135lbs. I can't see any difference yet from this first 8lbs but I feel better for better food habits and re establishing some exercise - i have had knee injury so am still only really walking the dog and doing some pilates/yoga and low level resistance work but looking forward to starting to run with the dog again soon. Exercise has a really positive effect on my mood.

I have noticed that I am a lot more thirsty so I'm drinking a lot more water which is a good thing and as my metabolism has slowed down and I'm going to the bathroom (for a nr 2 sorry TMI) less than I normally do and so this is making me drink the extra water which I'm usually terrible with. I am making efforts to increase my fiber which is also helping and also means drinking more water. - I am making sure I have fruit and seeds to help. Its easy to end up being all focussed on Protein and scared of any fat and carbs so I'm trying to keep a balance. I'm inheritantly lazy about food and don't enjoy preparing it and am rather disorganised about food shopping.

What are peoples good go to meals? So far I'm eating
Face fat free yoghurt with Chia and fruit and seeds or eggs any which way for breakfast sometimes with bacon medallions.
I've made batch portions of meatballs in tomato sauce with kidney beans and veg (Kind of like a chilli) .
Chicken with sweet potato roasted dry in the air fryer with green salads or any green veg.
And some easy chicken broth and veg soups.
Dr Kargs high protein ementaal and seeds crackers with hummus and tomatoes is one of my favourite lunches/snacks.
Ramen with noodles and veg and chicken/protein of some kind.
Feeling completely uninspired food wise really. The only thing I seem to want to eat a lot of is fruit which is high in sugar. I'm trying to eat some raw carrots and cucumber or celery to snack on with hummus or tsasiki.
I've cut down on my bread/gluten intake as I suspect it's not that good for me - If I have it I stick to sourdough or gluten free. I am v susceptible to inflammation based conditions and bread and yeast don't leave me feeling great. Also once I get in the habit of eating bread it ends up being all I eat. Toast toast and more toast....
Oops this was long!

Shedmistress · 23/09/2026 12:26

AxisofEvelKnievel · 22/09/2026 16:54

Have you got a link to the golden dose thread? I’m having trouble finding it.

there are a couple on the first page of this board.

mousey100 · 23/09/2026 13:17

Anyone else not seeing any weight loss after 4.5 weeks? Is that not long enough? What am I doing wrong? Is it my ADHD brain just thinking about food all the time? I was hoping for some sort of food noise switch off. Maybe I'm just eating out of habit? Moving up to 0.5 next week. Also, read something that suggested you don't lose fat, you lose muscle. Am I being naive to have thought the fat would go first? Doubting if this is actually a good idea. It's all quite confusing!

crumpetwithcheese · 23/09/2026 14:00

Hoping I can join you all, collecting my first jab today and really nervous to start!
Any side effects to be wary of and how to overcome these?
Thanks! X

SashaRose · 23/09/2026 17:15

FMLpassthegin · 23/09/2026 12:13

Hi all,
Please may I join? I started on Sept 6th. I started with Wegovy and have one more jab left and then for my next batch I'm switching to Mounjaro.
I'm injecting every Monday so I've just used my third WG 0.25 and weighing in 'officially' on wednesdays.

SW Day Sept 6: 76.6kg (168.9 lbs)
Week 1 (Weds) Weigh in Sept 9: 75.9kg (167.3lbs)
Week 2 (Weds) Weigh in Sept 16th: 74.6kg (164.4lbs)
Week 3 (Weds) Weigh in Sept 34rd: 72.9kg (160.4 lbs)
GW 58-60kg (@130lbs).

Side effects / Experience so far:
Have been minimal. I've found weds/thurs is when I feel a bit 'blah' kind of hungover headache ish, or super mild nausea. I am not finding that I feel any different from food choices - i've been able to drink, eat sugary things or fatty things without feeling sick which I've heard is mean to happen but I've noticed the feeling fuller on smaller portions and definitely less cravings or 'food noise' around wanting to reach for sweet treats or to have an alcoholic drink. I've definitely cut down my drinking and snacking on quick fix cookies/sweets as a result which is was one of my main motivations for doing this.

My why.
Over the summer I noticed with the crazy heat I was exercising far less and tending to drink much more regularly - a glass of rose was becoming a kind of daily 'end of the day' marker and I didn't like that! I find summer school holidays (despite having grown up kids) really hard for maintaining routines and I'm relieved to be back to 'term time' and re establishing workout routines and healthier habits.

I'm AuDHD so I find I'm quite all or nothing with food. I can forget to eat and then suddenly be starving at the end of the day. The impulsive side and dopamine ADHD side of me can be prone to binge eating sugar and carbs and the Autististic part of me can then become quite over disciplined so I'm hoping this might help me establish a better balance with the dopamine rewards from sugar and alcohol etc being taken down by the GLP1.

I take stimulant meds but they haven't really had any impact on my appetite or cravings which I know can be a bonus side effect for some people - that being said I think I metabolise them really fast... I'm 5.6ft and have put on quite a bit of weight for me and I hate it so keen to get back into the 130's where my clothes feel better and I feel like I can sit comfortably a few pounds either side of around 130-135lbs. I can't see any difference yet from this first 8lbs but I feel better for better food habits and re establishing some exercise - i have had knee injury so am still only really walking the dog and doing some pilates/yoga and low level resistance work but looking forward to starting to run with the dog again soon. Exercise has a really positive effect on my mood.

I have noticed that I am a lot more thirsty so I'm drinking a lot more water which is a good thing and as my metabolism has slowed down and I'm going to the bathroom (for a nr 2 sorry TMI) less than I normally do and so this is making me drink the extra water which I'm usually terrible with. I am making efforts to increase my fiber which is also helping and also means drinking more water. - I am making sure I have fruit and seeds to help. Its easy to end up being all focussed on Protein and scared of any fat and carbs so I'm trying to keep a balance. I'm inheritantly lazy about food and don't enjoy preparing it and am rather disorganised about food shopping.

What are peoples good go to meals? So far I'm eating
Face fat free yoghurt with Chia and fruit and seeds or eggs any which way for breakfast sometimes with bacon medallions.
I've made batch portions of meatballs in tomato sauce with kidney beans and veg (Kind of like a chilli) .
Chicken with sweet potato roasted dry in the air fryer with green salads or any green veg.
And some easy chicken broth and veg soups.
Dr Kargs high protein ementaal and seeds crackers with hummus and tomatoes is one of my favourite lunches/snacks.
Ramen with noodles and veg and chicken/protein of some kind.
Feeling completely uninspired food wise really. The only thing I seem to want to eat a lot of is fruit which is high in sugar. I'm trying to eat some raw carrots and cucumber or celery to snack on with hummus or tsasiki.
I've cut down on my bread/gluten intake as I suspect it's not that good for me - If I have it I stick to sourdough or gluten free. I am v susceptible to inflammation based conditions and bread and yeast don't leave me feeling great. Also once I get in the habit of eating bread it ends up being all I eat. Toast toast and more toast....
Oops this was long!

Thanks for your post, great to read and we are starting from a similar point. Out of interest what made you want to switch to Mounjaro?

FMLpassthegin · 23/09/2026 17:23

SashaRose · 23/09/2026 17:15

Thanks for your post, great to read and we are starting from a similar point. Out of interest what made you want to switch to Mounjaro?

It is meant to have faster weight loss results essentially.

NNYYCC · 23/09/2026 17:42

user626 · 19/09/2026 11:30

@imanastronauthow do you manage the constipation? I’m really struggling with it. I’m eating lots of vegetables and fruit and I’m taking a fibre supplement every day but still struggling.

Dried apricots and peppermint tea was recommended to me by my surgeon after anesthetic - elegant tasty and does the job.

NNYYCC · 23/09/2026 17:51

mousey100 · 23/09/2026 13:17

Anyone else not seeing any weight loss after 4.5 weeks? Is that not long enough? What am I doing wrong? Is it my ADHD brain just thinking about food all the time? I was hoping for some sort of food noise switch off. Maybe I'm just eating out of habit? Moving up to 0.5 next week. Also, read something that suggested you don't lose fat, you lose muscle. Am I being naive to have thought the fat would go first? Doubting if this is actually a good idea. It's all quite confusing!

I lost 4kg in first couple of weeks on 2.5 MJ - since then nothing….took the golden 5th dose of 2.5 last week and now upped to 5 taken today. Need a turbo boost.

Eyelashesoffire · 23/09/2026 20:03

Great to hear so many people are getting on so well. I had my first dose on Sunday and apart from some mild nausea in the mornings I've had no side effects. Apart from feeling more energetic, less achey and not hungry at all. I could easily forget to eat, I'm only eating by routine really. I don't want to lose weight too fast and lose hair or end up with lots of loose skin.

It's an absolute revelation to feel like this and all I can think is some people must be like this naturally, I know my sister is. On Sunday I had one biscuit and enjoyed it so much I had 3 more. On Monday after my first jab, I had half a biscuit and thought I could take it or leave it. The motivation, reward was totally gone.

I went to a weights class today as I don't want to just lose muscle.

I really really hope I can get by on 2.5mg. Is anyone here staying on 2.5mg and finding it still works?

Obeseandashamed · 24/09/2026 12:03

Hello, hope you don’t mind me joining. I’m a serial dieter who’s really struggled with my weight for my entire adult life hence my username! I took my first jab at the weekend and I’m down 2lbs already though I know it’s likely water weight. I’m not the best at keeping up with fast moving threads so hope you don’t mind me dipping in and out of this one. I’ve had no side effects this week other than awful burps. Have bought some peptobismol and also started drinking more peppermint tea in the hope that it helps 🤞🏽

AxisofEvelKnievel · 24/09/2026 13:59

@Eyelashesoffire Yes I've opted to stay on 2.5 mg for my second month as I lost 4.5 kg in the first month with only mild side-effects (audible but non-sulphurous burps). I'm sure the weight loss will slow down in month two but I only had a bit under two stone to lose (now one and a bit).