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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Starting May 26 Group (MJ)

988 replies

madeinthe80z · 25/04/2026 22:11

My first jabs arrived today. Thinking of starting Wednesday which is technically end of April but wanted to start a new group for anyone starting soon!

Nervous but kind of excited for good results. Watched a YouTube video instruction for the pen before, I might get my husband to do it for me!!

Anyone want to join me and share / support each other??

OP posts:
Thread gallery
9
Boreded · 19/06/2026 13:05

I’m going to be making my 5s last 8 weeks, I’ll let you know if I notice any change in whether it works, but I’m going to bet it absolutely does still work, even if it doesn’t it’ll give me a placebo effect so 🤷‍♀️

In other news, I’d promised my son a Chinese when he finished his last exam, and I had been umming and ahhing about whether I would have any. I bit the bullet and had: 108g chicken fried rice, 65g chicken from his chicken satay dish, and 5 spoons of sauce. Fortunately our local Chinese does a very runny satay and clearly not using peanut butter, plus it isn’t sweet at all. Best estimate on calories from chat gpt and online had me at 450ish

BUT…last night I suffered. I had indigestion to the point I was almost sick, burping more than 10 times a minute and in absolute agony. So now my favourite food is completely off the table, so that’s a bonus. Now my only vice is Coca Cola, but I only have 1 can a day (maximum) and I have no intention of cutting it out because it’s my favourite thing.

mollio · 19/06/2026 16:13

PuppyKeep · 19/06/2026 12:40

How does the 30 day max thing work when we're encouraged to order our next pen only two weeks into the current one?

I will end up with a little stockpile I reckon as my supplier does exactly that , asks me to order two weeks before it’s due …. I’m not sure yet what I will do long term as I have a 5mg pen but am taking 3.75. I may end up going to 5mg eventually ( or soon even )

PuppyKeep · 19/06/2026 16:16

mollio · 19/06/2026 16:13

I will end up with a little stockpile I reckon as my supplier does exactly that , asks me to order two weeks before it’s due …. I’m not sure yet what I will do long term as I have a 5mg pen but am taking 3.75. I may end up going to 5mg eventually ( or soon even )

How do you do the 3.5? can you provide instruction please.

How are you finding that dosage re: suppression and weight loss?

mollio · 19/06/2026 18:34

On a 5 mg pen I click to 45 clicks instead of 60 which is a full dose and would bring the pen around to nr 1 . I find the suppression high , lasts linger than the 2.5 , hard to eat on day 2/3 but then still suppresses but able to eat the rest of the week , I will do one more of 3.75 tomorrow and should be able to tell then properly . I have been in Italy the past week so I don’t know about weight loss this week !! Tell you tomorrow !

NettleTea · 19/06/2026 18:58

my 5mg has arrived but Im sticking with the 2.5 for it, so will also be stretch dosing and keeping in the fridge. I was thinking about a mini fridge for the bedroom for the stockpile but fell down a medical grade portable fridge rabbit hole with prices which would wipe out any savings! crazy where you can end up late night browsing.
Im wiped out today, but I have been doing some mentally challenging days getting my first exhibition ready for tomorrows private view, and then working in the heat. Im not sleeping well. Im waking up alot and for once I dont think its the CPAP, so am wondering if its the medication.
So just checking for those who are doing lower doses - does the pen still only allow 4 doses and lock up? so are you drawing off, or are you cracking it to carry on and does that mean the clicks are harder to hear when you do the crack?

PuppyKeep · 19/06/2026 19:23

mollio · 19/06/2026 18:34

On a 5 mg pen I click to 45 clicks instead of 60 which is a full dose and would bring the pen around to nr 1 . I find the suppression high , lasts linger than the 2.5 , hard to eat on day 2/3 but then still suppresses but able to eat the rest of the week , I will do one more of 3.75 tomorrow and should be able to tell then properly . I have been in Italy the past week so I don’t know about weight loss this week !! Tell you tomorrow !

thanks so much!

KittensAndCupcakes · 19/06/2026 20:47

PuppyKeep · 19/06/2026 11:36

How has your loss on the scales been?

And how often do you lift weights?

I try to lift at least every other day.

Well done on lifting on alternate days. I do twice a week and a third time if I manage it. I’m doing it at the gym. Considered buying some dumbbells for home, but it would just be more stuff in the house.

KittensAndCupcakes · 19/06/2026 20:55

NettleTea · 19/06/2026 18:58

my 5mg has arrived but Im sticking with the 2.5 for it, so will also be stretch dosing and keeping in the fridge. I was thinking about a mini fridge for the bedroom for the stockpile but fell down a medical grade portable fridge rabbit hole with prices which would wipe out any savings! crazy where you can end up late night browsing.
Im wiped out today, but I have been doing some mentally challenging days getting my first exhibition ready for tomorrows private view, and then working in the heat. Im not sleeping well. Im waking up alot and for once I dont think its the CPAP, so am wondering if its the medication.
So just checking for those who are doing lower doses - does the pen still only allow 4 doses and lock up? so are you drawing off, or are you cracking it to carry on and does that mean the clicks are harder to hear when you do the crack?

@NettleTea You could get a fridge thermometer? Good luck with the art show and hope you get some decent sleep.

Golden dosers- like @NettleTea I’d also be glad to know how to click further than the fourth dose. Is it just brute force??

ShakySwan · 19/06/2026 21:04

Hi everyone. I’m on week 6 of 2.5 and it’s not having a lot of impact right now (which is great because I’m not longer feeling sick all the time but also pretty hungry). I plan to move to 5 for the next pen but can I just inject 2x 2.5 now? And get my next one earlier? Anyone done that?

madeinthe80z · 19/06/2026 21:33

KittensAndCupcakes · 19/06/2026 20:55

@NettleTea You could get a fridge thermometer? Good luck with the art show and hope you get some decent sleep.

Golden dosers- like @NettleTea I’d also be glad to know how to click further than the fourth dose. Is it just brute force??

Yep just brute force. It really wasn’t difficult at all!

OP posts:
madeinthe80z · 19/06/2026 21:34

ShakySwan · 19/06/2026 21:04

Hi everyone. I’m on week 6 of 2.5 and it’s not having a lot of impact right now (which is great because I’m not longer feeling sick all the time but also pretty hungry). I plan to move to 5 for the next pen but can I just inject 2x 2.5 now? And get my next one earlier? Anyone done that?

I’ve also wondered this. I haven’t looked into it though. I don’t think anyone in this thread will have but you could ask in one of the threads that has been going for a good few months maybe?

OP posts:
7238SM · 19/06/2026 21:51

PuppyKeep · 19/06/2026 16:16

How do you do the 3.5? can you provide instruction please.

How are you finding that dosage re: suppression and weight loss?

I used this calculator just today. I've bought a 5mg pen, but didn't want to even go to 3.75mg after horrendous side effects last week using the golden dose on my 1st pen, which was approx 3.8mg. So today, I dialled in 3mg and so far, have felt absolutely fine,

monj.co.uk/mounjaro-click-calculator/

minnymoobear · 19/06/2026 22:07

mollio · 19/06/2026 18:34

On a 5 mg pen I click to 45 clicks instead of 60 which is a full dose and would bring the pen around to nr 1 . I find the suppression high , lasts linger than the 2.5 , hard to eat on day 2/3 but then still suppresses but able to eat the rest of the week , I will do one more of 3.75 tomorrow and should be able to tell then properly . I have been in Italy the past week so I don’t know about weight loss this week !! Tell you tomorrow !

Can I just ask about this as I’ve read somewhere that it doesn’t count as a 3.75mg dosage as what you’re actually injecting as a higher strength so the strength is still 5mg but you’re just taking less of it, which makes sense - I think!

anyone know or is that something else?!

UntilTheVeryEnd · 19/06/2026 22:21

ShakySwan · 19/06/2026 21:04

Hi everyone. I’m on week 6 of 2.5 and it’s not having a lot of impact right now (which is great because I’m not longer feeling sick all the time but also pretty hungry). I plan to move to 5 for the next pen but can I just inject 2x 2.5 now? And get my next one earlier? Anyone done that?

Probably completely against advice but my husband did this with his 4th and golden dose on his first 2.5mg. He was able to order the next pen after like 3 weeks so the 5mg was waiting after his 4th (2x2.5mg) he did it because he was getting zero suppression and was impatient to feel some effects. He just cranked the dose, delivered it, then cranked it again and delivered the second injection. He lived to tell the tale and having much more success with the 5mg

Boreded · 19/06/2026 23:42

ShakySwan · 19/06/2026 21:04

Hi everyone. I’m on week 6 of 2.5 and it’s not having a lot of impact right now (which is great because I’m not longer feeling sick all the time but also pretty hungry). I plan to move to 5 for the next pen but can I just inject 2x 2.5 now? And get my next one earlier? Anyone done that?

Yeah you can double dose to get to the 5.

And my husband just forced the golden dose for me too, just took a bit of force to get it round.

Boreded · 19/06/2026 23:45

minnymoobear · 19/06/2026 22:07

Can I just ask about this as I’ve read somewhere that it doesn’t count as a 3.75mg dosage as what you’re actually injecting as a higher strength so the strength is still 5mg but you’re just taking less of it, which makes sense - I think!

anyone know or is that something else?!

5mg is the total amount of the medication you would get if you took a full dose. If you take 3/4 of a dose you’ll get 3.75mg.

it doesn’t matter what strength the formula is, the percentage of the dose you take is the same as the percentage of the medication. So 3/4 of a 10mg pen is 7.5mg for example.

the dose is stronger as you go up the pen, but all that means is that the medication is more concentrated. If you take a set percentage of it, then you get that percentage of the total medication.

minnymoobear · 20/06/2026 00:32

Boreded · 19/06/2026 23:45

5mg is the total amount of the medication you would get if you took a full dose. If you take 3/4 of a dose you’ll get 3.75mg.

it doesn’t matter what strength the formula is, the percentage of the dose you take is the same as the percentage of the medication. So 3/4 of a 10mg pen is 7.5mg for example.

the dose is stronger as you go up the pen, but all that means is that the medication is more concentrated. If you take a set percentage of it, then you get that percentage of the total medication.

Thanks @Boreded appreciate your explanation but that has kind of confused me even more 🤪🥴

Surely, the strength of the dosage does matter…? You start at a low dosage and then you work your way up. It’s not just about the amount of the liquid but how strong it is, right?

So the 10mg will be stronger/more potent than the 2.5mg - so aren’t you just taking a smaller dose at a stronger/higher intensity?

i know what I’m trying to say but can’t explain 🥴

Boreded · 20/06/2026 00:42

minnymoobear · 20/06/2026 00:32

Thanks @Boreded appreciate your explanation but that has kind of confused me even more 🤪🥴

Surely, the strength of the dosage does matter…? You start at a low dosage and then you work your way up. It’s not just about the amount of the liquid but how strong it is, right?

So the 10mg will be stronger/more potent than the 2.5mg - so aren’t you just taking a smaller dose at a stronger/higher intensity?

i know what I’m trying to say but can’t explain 🥴

Let’s say a dose is 10mls (it isn’t but it makes the numbers easier)

every pen will have the same 10ml doses but the strength is different.

so if you take 3/4 of a 2.5 dose or a 5 dose, you still get 7.5mls, but one is stronger than the other…that means 7.5mls of 2.5 is a total of 1.875mg, but if you took 7.5mls of the 5 dose it is 3.75mg.

The mg of the pen is the amount of medication in one dose, the dose size is always the same, it is just stronger in the higher pens. To get a 2.5mg dose when you use the 5mg pen you only need to use half of the dose size because it is stronger. It is the same as if you got a double strength paracetamol tablet, you would need two regular paracetamol to have the same dose, even though each pill is the same size.

OP posts:
MrsO2b · 20/06/2026 07:09

minnymoobear · 20/06/2026 00:32

Thanks @Boreded appreciate your explanation but that has kind of confused me even more 🤪🥴

Surely, the strength of the dosage does matter…? You start at a low dosage and then you work your way up. It’s not just about the amount of the liquid but how strong it is, right?

So the 10mg will be stronger/more potent than the 2.5mg - so aren’t you just taking a smaller dose at a stronger/higher intensity?

i know what I’m trying to say but can’t explain 🥴

I think the medication is the same strength in every pen, you're just taking more of it if you go up a pen/dose

Boreded · 20/06/2026 08:35

MrsO2b · 20/06/2026 07:09

I think the medication is the same strength in every pen, you're just taking more of it if you go up a pen/dose

That’s not true, the pen would have 6 times the amount of liquid in the 15mg if that were the case, and that is not what happens.

The higher the mg on the pen, the more concentrated the medication is.

mollio · 20/06/2026 10:00

minnymoobear · 19/06/2026 22:07

Can I just ask about this as I’ve read somewhere that it doesn’t count as a 3.75mg dosage as what you’re actually injecting as a higher strength so the strength is still 5mg but you’re just taking less of it, which makes sense - I think!

anyone know or is that something else?!

I see that the poster Bordeded answered your post already and explained it very well . The clicks are the same for whatever percentage of the pen dose you want to use. So for example I use 45 clicks of a 5mg pen which is 3.75. But if I took 45 clicks ( 45/60 ) of a 10 mg pen it would be a dose of 7.5.
the total dose is always 60 clicks no matter what dose it is ( it’s the same amount of liquid in each pen , just the strength of the liquid can be higher or lower )
I hope that explains it a bit ?
I got back from holidays last night and happy that I only put in 2 lbs as I drank every day and ate whatever I wanted pretty much ( but was pretty sensible within that !)
I took 3.75 this morning . 🤞🤞will continue with good suppression

Boreded · 20/06/2026 12:05

mollio · 20/06/2026 10:00

I see that the poster Bordeded answered your post already and explained it very well . The clicks are the same for whatever percentage of the pen dose you want to use. So for example I use 45 clicks of a 5mg pen which is 3.75. But if I took 45 clicks ( 45/60 ) of a 10 mg pen it would be a dose of 7.5.
the total dose is always 60 clicks no matter what dose it is ( it’s the same amount of liquid in each pen , just the strength of the liquid can be higher or lower )
I hope that explains it a bit ?
I got back from holidays last night and happy that I only put in 2 lbs as I drank every day and ate whatever I wanted pretty much ( but was pretty sensible within that !)
I took 3.75 this morning . 🤞🤞will continue with good suppression

Edited

great job @mollio small gain when having proper holiday food rather than focussing on the diet. This is what I’m hoping for when I go, I know I’ll be drinking a small amount and also more likely to eat more food, so a small gain is ok, it’s just a fluctuation really in the scheme of things isn’t it.

hope you had a good time

Popstarrrrr · 21/06/2026 12:16

5th jab today. I tried to force the pen, couldn't do it so used an insulin needle I'd bought to extract the very last dose. Weight loss has been rubbish this week which is my fault. Have barely moved and been eating loads of sweets.

SW 77kg
PW 74.4kg
CW 74.7kg
GW 65kg

I have 5mg pen in the fridge but didn't want to use it this week in case of side effects, I've loads of in person work events over the next week.

I'm hoping I can keep myself on track to at least reach 70kg by the end of July.

JojoButBetter · 25/06/2026 09:50

So I have just taken my first 7.5mg dose. I was doing O.K on 5mg but was finding by day 5 I wanted to eat everything!

Depending on how I get on, I may continue on 7.5mg, or go back to 5mg but inject every 5 days.

I'm not sure if anyone on this board has decided to go up to 7.5mg yet, so I will keep on posting side effects if any!