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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Starting May 26 Group (MJ)

988 replies

madeinthe80z · 25/04/2026 22:11

My first jabs arrived today. Thinking of starting Wednesday which is technically end of April but wanted to start a new group for anyone starting soon!

Nervous but kind of excited for good results. Watched a YouTube video instruction for the pen before, I might get my husband to do it for me!!

Anyone want to join me and share / support each other??

OP posts:
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TeamsThemeTune · 14/06/2026 21:23

madeinthe80z · 14/06/2026 20:40

What calories does everyone aim for? I aim not to go over 1600 per day and I take an average across the week but reading many posts on here, a lot of people seem to be aiming much lower. At my current 2.5mg dose I’d say 1500-1600 per day averaged across the week is all I can achieve at this dose. I feel like I’ll need to go up a dose to be able to reduce my calories further, which is what I’m thinking of doing with my next pen…

I'm working on a 500 cal deficit from my TDEE, so I'm aiming for 1,100.

I'm pretty sedentary though - desk job, get a couple of 20-30 minute walks in per day, but that's it. I do go over calories occasionally, but my weekly average is under 1,200 per day.

I'm annoyed with myself though - pre-COVID I was lifting heavy weights with a PT, running and doing pilates. But I had the time as I was made redundant and decided to spend on my health. Had to go back to work so I'm out of the house 12+ hours a day, had my ovaries out so instant menopause, and have very little mojo left as I'm permanently knackered. Excuses, excuses...

Popstarrrrr · 14/06/2026 21:30

I'm not counting calories. Trying to make good food choices with higher protein and less volume. I'm hoping by the time I come off WLI. I've completely overhauled my diet. Time will tell whether this strategy works.

Tulipwood · 15/06/2026 06:58

TeamsThemeTune · 14/06/2026 21:23

I'm working on a 500 cal deficit from my TDEE, so I'm aiming for 1,100.

I'm pretty sedentary though - desk job, get a couple of 20-30 minute walks in per day, but that's it. I do go over calories occasionally, but my weekly average is under 1,200 per day.

I'm annoyed with myself though - pre-COVID I was lifting heavy weights with a PT, running and doing pilates. But I had the time as I was made redundant and decided to spend on my health. Had to go back to work so I'm out of the house 12+ hours a day, had my ovaries out so instant menopause, and have very little mojo left as I'm permanently knackered. Excuses, excuses...

They don’t sound like excuses at all! Be kind to yourself

PuppyKeep · 15/06/2026 09:32

CherryViper · 13/06/2026 17:55

@TeamsThemeTune I'm sure it will be fine.

I'm aiming for around 1000 calories a day and am losing 1lb a week. I went up to 5mg last time. I'm not feeling any bloating, fullness or nausea.

Are you very short in height?

PuppyKeep · 15/06/2026 09:35

VanillaLatteGirl · 13/06/2026 18:25

Is anyone else finding that they are starving the day after their injection day? Did my 6th injection yesterday, still on 2.5 and lost just over a stone. Only side effects have been reflux, which I get anyway. Totally happy with the suppression 2.5 is giving me - went away last week and still lost 1.5lbs and the suppression was still great when I injected last night. However today and the previous 2 Saturdays (inject on a Friday evening) I have had a sicky gnawing tummy that's made me eat more than I normally would and actually ate a fair bit of chocolate, which is something I've had no interest in up until today. I had rotten reflux last night and had to get up for quite a while to get it settled and I'm wondering if that's the cause of it. Anyone else had this?

I'm starving by day 5 for sure, but not day 2.

Time to go up a dose?

NettleTea · 15/06/2026 09:36

I am using the Nutricheck at the moment and logging everything. I am using a target of 1200 a day, with a higher protein. Im trying to get into a routione where I learn what I can have. I think I need to admit that I was previously eating badly - not eating much but snacking on unhealthy choices.

PuppyKeep · 15/06/2026 09:40

Hillsmakeyoustrong · 14/06/2026 10:50

Hi all, no weigh in update as that happens on a Wednesday, but my period was delayed by about a week. I think its defo due to mounjaro. Will be interested to see if its heavier or lighter than usual...

mine is heavier.... oh boy

3oldladiesstuckinalavatory · 15/06/2026 11:03

Weigh day for me and it’s shifting! 4kg down in 3 weeks.

4th jab last night and feeling a bit more positive.

Only 25kg left to go… 👀🤣💪

3oldladiesstuckinalavatory · 15/06/2026 11:05

Now the numbers are changing I need to work on building muscle. Anyone got any simple home workouts to share?

I have a kettlebell and some hand weights (all. 6kg) - I just need some inspiration of what to do with them!

madeinthe80z · 15/06/2026 14:08

3oldladiesstuckinalavatory · 15/06/2026 11:05

Now the numbers are changing I need to work on building muscle. Anyone got any simple home workouts to share?

I have a kettlebell and some hand weights (all. 6kg) - I just need some inspiration of what to do with them!

Same! I have had a chat with ChatGPT and got some really really simple exercises I can do pretty much anywhere throughout the day to try and address my flattening bum! Maybe give that a try or go to you tube and maybe chose 5 beginners workouts and treat it like a little interview process to see who’s you like best, might add a bit more motivation doing it that way too!

OP posts:
Boreded · 15/06/2026 14:14

madeinthe80z · 14/06/2026 20:40

What calories does everyone aim for? I aim not to go over 1600 per day and I take an average across the week but reading many posts on here, a lot of people seem to be aiming much lower. At my current 2.5mg dose I’d say 1500-1600 per day averaged across the week is all I can achieve at this dose. I feel like I’ll need to go up a dose to be able to reduce my calories further, which is what I’m thinking of doing with my next pen…

I’m significantly lower than that but very conscious it is not healthy long term. Im counting right down to weighing my mayo on a spoon on the kitchen scales so that I get it right, and I’m at around 850 on average (down to 750 as a minimum).

Im on the lowest dose and with the exception of a couple of days on my period, I have not experienced hunger at all. BUT…I have OCD so it may well be that this is actually helping.

I have an incredibly sedentary lifestyle, working from home and rarely go out so not using energy like a normal person though. I’m conscious that this needs to change, and that when I am actively trying to do more I will need to eat more.

I think the jabs could be very dangerous to someone with anorexia. Because I have no desire to starve myself, but I don’t think I would notice if I didn’t eat for 24 hours at a time, imagine that for someone who does want to starve themselves…DANGEROUS.

This is the first time I’ve been able to significantly calorie restrict and not feel unwell or hangry. And it’s allowing me to force out the bad routines that I had built up very easily, I’m just hoping that these become new lifestyle changes so that when I’m off the jabs next year I can just eat a sensible diet and exercise without slipping back.

Anyway, what I was trying to say is that I’m doing 12 weeks of significant calorie restriction, before upping my exercise and going into the 1200 region, hopefully with much healthier attitudes to food. I just needed a full reset which can be difficult when you have OCD and need (for me anyway) repetition and routine.

TeamsThemeTune · 15/06/2026 15:02

Parcel finally arrived - it wasn't cool, but it wasn't warm, so I've jabbed. Next time I'm going to pick up at the post office - it's too difficult to keep this secret.

My daughter's at home today and keeps popping up and down the stairs - I had to open the parcel, dispose of the outer bag with a big red "refrigerate on receipt" sticker on it, unwrap everything, get rid of the outer box, bin the wool and the gel packs, hide the pen box to be disposed of somewhere in a galaxy far, faraway, leg it into the downstairs bog and jab, then hide the pen, the needles, the swabs and the MAHOOSIVE sharps box at the back of my wardrobe. The stress!

Cece92 · 15/06/2026 16:09

I done my third jab last night and surprisingly feel good today last 2 jabs I never lol! Took myself off for a swim today. Going to try for swimming Wednesday too xx

MrsBuntyS · 15/06/2026 18:09

Had a nightmare day today! Woke up to a very heavy period. After 90 days of nothing. I’ve only had about 5 periods in the last two years. I’m 49 and not on HRT and had 5 jabs so far. Then got an absolute monster migraine, haven’t had one that bad before, couldn’t see or read. Had a numb arm and face, it really freaked me out but I’m ok now. Had to eat because I think the low calories, around 1,000 a day didn’t help. Hopefully this won’t happen again. I won’t deterred though!!!

7238SM · 15/06/2026 18:47

@MrsBuntyS That sounds awful. Do you often get migraines like that? Had you drunk much water? I'm glad it resolved.

I read that being overweight/obese can delay menopause. I'm 48 and still having very regular periods, albeit closer together, so my 32 day cycle is now 27day cycle. I wonder a the change in weight/hormones if what caused your bleed?

MrsBuntyS · 15/06/2026 19:04

God knows. I don’t usually get migraines, only a couple a year. Pretty sure it’s the GLP 1’s messing with my hormones or correcting them! Horrendous.

Cece92 · 15/06/2026 19:57

MrsBuntyS · 15/06/2026 18:09

Had a nightmare day today! Woke up to a very heavy period. After 90 days of nothing. I’ve only had about 5 periods in the last two years. I’m 49 and not on HRT and had 5 jabs so far. Then got an absolute monster migraine, haven’t had one that bad before, couldn’t see or read. Had a numb arm and face, it really freaked me out but I’m ok now. Had to eat because I think the low calories, around 1,000 a day didn’t help. Hopefully this won’t happen again. I won’t deterred though!!!

I have PCOS and suffer from hormonal migraines. I got my period a week after my first jab and then a migraine a few days later I had to ring the GP for some sumatriptan. I’d say keep drinking and eat small snacks if you can. I have really stuck to my 2-3L since that migraine and have had 0 side effects this jab. I thought it was weird I had a period after my first jab and I take birth control xx

NettleTea · 16/06/2026 08:06

I had headaches last week. I think it was a combination of not drinking enough water and leaving too long between breakfast and lunch - this drug takes no prisoners if you do my usual of forgetting to eat for 8 hours. Also remember that you are losing weight so burning up and releasing all kind of crap tied up in those fat cells - hormones metabolites, etc. they are going into your blood stream and affecting how you feel.

Boreded · 16/06/2026 11:53

MrsBuntyS · 15/06/2026 19:04

God knows. I don’t usually get migraines, only a couple a year. Pretty sure it’s the GLP 1’s messing with my hormones or correcting them! Horrendous.

I got my first one in probably 18 months last week…I feel your pain.

Are you extra hungry this time? I felt ravenous for the first couple of days, no suppression at all, had to white knuckle it through the week.

Once I was done though the weight loss started to come back and the suppression works again

madeinthe80z · 16/06/2026 13:05

Just ordered my first 5mg pen (hopefully I will be approved as I have changed supplier AND requested a higher dose) so I will have done 10 x 2.5mg doses and then will move up to 3.75mg week after next by counting the clicks and see how I feel there before moving up to the full 5!

I have lost 13lb in 8 weeks but half of that was in the first 3 weeks and it’s been a bit of a slog the last 3 weeks! Hoping this will give me another boost.

OP posts:
KittensAndCupcakes · 16/06/2026 13:56

I’m the same @Popstarrrrr Not counting calories. Just eating normal food, slightly less portion size and minimal snacking. I am
counting protein and generally manage in the region of 100g.

On the headache front, the first couple of weeks were quite full on, but now just back to normal with headaches if dehydrated (which is occasional) or tired (which is often).

ByNiftyPombear · 16/06/2026 17:10

Have also been struggling with headaches, the last 24 hours have been bad, pretty sure was a migraine (never had one before) but had light sensitivity, dizziness and nausea. Drinking plenty, could be hormonal but not something I’ve experienced before. Have such extreme suppression I’m really struggling to eat, even preparing food for the family is proving too much. Was due to jab last night but postponed as was hoping I’d feel better today. Haven’t felt quite right since the weekend - had a Chinese take away (chose highest protein, lowest cal options and ate a small portion) but it made me feel sick, had bad reflux and caused constipation (not being helped by now struggling to eat anything). And just so, so tired. Do I hold off injecting until I’m feeling better or bite the bullet? Any thoughts? For context, this would be injection 8 I think, and have been on 2.5 throughout.

Hillsmakeyoustrong · 16/06/2026 18:11

@ByNiftyPombear I think you should delay personally and that is what I would do but I am very cautious when my body protests. For instance, my three jabs to date have been 1.25mg as I didn't want to go straight on to 2.5mg. Im due tonjab again tomorrow and will go up to 2.5mg now I feel my body is used to it but Im nervous. I personally think if you're feeling that level of suppression and experiencing those SE, thats enough for now.

Hillsmakeyoustrong · 16/06/2026 18:13

Has anyone felt they have been more anxious on Mounjaro? I have low level anxiety anyway but its been through the roof the last 3 weeks since I started.

KittensAndCupcakes · 16/06/2026 18:24

ByNiftyPombear · 16/06/2026 17:10

Have also been struggling with headaches, the last 24 hours have been bad, pretty sure was a migraine (never had one before) but had light sensitivity, dizziness and nausea. Drinking plenty, could be hormonal but not something I’ve experienced before. Have such extreme suppression I’m really struggling to eat, even preparing food for the family is proving too much. Was due to jab last night but postponed as was hoping I’d feel better today. Haven’t felt quite right since the weekend - had a Chinese take away (chose highest protein, lowest cal options and ate a small portion) but it made me feel sick, had bad reflux and caused constipation (not being helped by now struggling to eat anything). And just so, so tired. Do I hold off injecting until I’m feeling better or bite the bullet? Any thoughts? For context, this would be injection 8 I think, and have been on 2.5 throughout.

So sorry to hear you are feeling so dreadful. It might not be caused by the jabs (dodgy Chinese?), but if it were me, I would hold off putting any further stress on my system and wait until I felt more normal. Really hope this passes soon for you.