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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Starting May 26 Group (MJ)

988 replies

madeinthe80z · 25/04/2026 22:11

My first jabs arrived today. Thinking of starting Wednesday which is technically end of April but wanted to start a new group for anyone starting soon!

Nervous but kind of excited for good results. Watched a YouTube video instruction for the pen before, I might get my husband to do it for me!!

Anyone want to join me and share / support each other??

OP posts:
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MrsO2b · 13/06/2026 18:22

TeamsThemeTune · 13/06/2026 16:16

Thanks @Boreded - I had a right panic there, I'm sure your'e right and it will be fine. It not like it's going to turn toxic overnight - worst case scenario is that it might not be as effective.

Just got to get through the weekend without eating all the bread and crisps!

I'm going to investigate suppliers who don't use RM for the next pen as they insist on a signature, and won't leave it in a safe place, which is mad really - I'm generally at home for basically 4 days a week, and I still missed it!

All the companies seem to use carriers who either want a signature or want a photo of it in your open doorway. It's understandable really, as it's medication. It's a bugger that you can't choose a delivery day though

VanillaLatteGirl · 13/06/2026 18:25

Is anyone else finding that they are starving the day after their injection day? Did my 6th injection yesterday, still on 2.5 and lost just over a stone. Only side effects have been reflux, which I get anyway. Totally happy with the suppression 2.5 is giving me - went away last week and still lost 1.5lbs and the suppression was still great when I injected last night. However today and the previous 2 Saturdays (inject on a Friday evening) I have had a sicky gnawing tummy that's made me eat more than I normally would and actually ate a fair bit of chocolate, which is something I've had no interest in up until today. I had rotten reflux last night and had to get up for quite a while to get it settled and I'm wondering if that's the cause of it. Anyone else had this?

madeinthe80z · 13/06/2026 19:11

VanillaLatteGirl · 13/06/2026 18:25

Is anyone else finding that they are starving the day after their injection day? Did my 6th injection yesterday, still on 2.5 and lost just over a stone. Only side effects have been reflux, which I get anyway. Totally happy with the suppression 2.5 is giving me - went away last week and still lost 1.5lbs and the suppression was still great when I injected last night. However today and the previous 2 Saturdays (inject on a Friday evening) I have had a sicky gnawing tummy that's made me eat more than I normally would and actually ate a fair bit of chocolate, which is something I've had no interest in up until today. I had rotten reflux last night and had to get up for quite a while to get it settled and I'm wondering if that's the cause of it. Anyone else had this?

Yep I’ve had this. Week 5 I think! My hunger fluctuates so much I’m struggling to find a pattern to be honest. I might start documenting it!

OP posts:
VanillaLatteGirl · 13/06/2026 19:27

I've not been bothered with anything else to be honest, so it's caught me a bit off guard. And I've certainly not felt hungry at all through the week. I injected about 6.30, and right up until then didnt feel hungry at all. Just had a sandwich for tea last night as I wasn't hungry, but I remember now that when i went to bed i felt a bit sickly. I feel like I could honestly eat a horse right now, but will be settling for egg on toast as I don't want a repeat of last night's reflux. Will make sure I take omeprazole from Thursday next week and see if that helps at all.

KittensAndCupcakes · 13/06/2026 21:04

VanillaLatteGirl · 13/06/2026 18:25

Is anyone else finding that they are starving the day after their injection day? Did my 6th injection yesterday, still on 2.5 and lost just over a stone. Only side effects have been reflux, which I get anyway. Totally happy with the suppression 2.5 is giving me - went away last week and still lost 1.5lbs and the suppression was still great when I injected last night. However today and the previous 2 Saturdays (inject on a Friday evening) I have had a sicky gnawing tummy that's made me eat more than I normally would and actually ate a fair bit of chocolate, which is something I've had no interest in up until today. I had rotten reflux last night and had to get up for quite a while to get it settled and I'm wondering if that's the cause of it. Anyone else had this?

This happened to me last week after jab 5. I woke up and was pretty hungry all day. That did pass though and my appetite wasn’t so big in the week.

I have also sometimes had nausea because I am hungry. Eating a bit has made it go away.

Hope your reflux and nausea settle.

3oldladiesstuckinalavatory · 13/06/2026 22:25

KittensAndCupcakes · 13/06/2026 21:04

This happened to me last week after jab 5. I woke up and was pretty hungry all day. That did pass though and my appetite wasn’t so big in the week.

I have also sometimes had nausea because I am hungry. Eating a bit has made it go away.

Hope your reflux and nausea settle.

Yes, me! This exact thing happened with jab 3 (the last one I did). Starving hungry the next day, then a lot of reflux / eggy burps. Really nasty. I’ve had no problems for the rest of the week, feeling really full and not up for eating much. All a bit the wrong way round?

3oldladiesstuckinalavatory · 13/06/2026 22:29

MrsO2b · 13/06/2026 18:22

All the companies seem to use carriers who either want a signature or want a photo of it in your open doorway. It's understandable really, as it's medication. It's a bugger that you can't choose a delivery day though

I’ve had mine delivered by two different pharmacies that both use Royal Mail. Twice they’ve just left it outside, no signature needed. We have a lovely postman though and he normally leaves stuff no problem.

MrsO2b · 13/06/2026 23:50

3oldladiesstuckinalavatory · 13/06/2026 22:29

I’ve had mine delivered by two different pharmacies that both use Royal Mail. Twice they’ve just left it outside, no signature needed. We have a lovely postman though and he normally leaves stuff no problem.

Mine comes by royal mail but they won't leave it without a signature

Rockgrin · 14/06/2026 07:35

Well, I wussed out!

Had the 5 mg pen ready, but started getting some side effects this week (week 4), so ordered another 2.5 mg pen. Took my first 2.5 out of the second pen this morning.

I hope it's the right decision, but I could barely eat this week so I think it is.

Weight this morning is 17 stone 4.5 pounds, so that's 16.5 pounds down after 4 weeks (was surprised I lost even 1 pound this week, it's that time of the month).

ByNiftyPombear · 14/06/2026 07:40

Hey been trying to scroll back to find the counting clicks info. Have downloaded a couple of charts but just want to confirm it tallies with what others have done/read. Says 30 clicks for 2.5 from a 5 pen? Just been approved for a 5 but still getting good suppression from 2.5, but went up to save money. Also does anyone know if you pull the pen out to the full dose then count clicks as you inject, and leave the other half “loaded” for next time, or count the clicks as you’re loading it then inject? But then guess the pen will lock after 4 injections? Thanks

madeinthe80z · 14/06/2026 08:04

ByNiftyPombear · 14/06/2026 07:40

Hey been trying to scroll back to find the counting clicks info. Have downloaded a couple of charts but just want to confirm it tallies with what others have done/read. Says 30 clicks for 2.5 from a 5 pen? Just been approved for a 5 but still getting good suppression from 2.5, but went up to save money. Also does anyone know if you pull the pen out to the full dose then count clicks as you inject, and leave the other half “loaded” for next time, or count the clicks as you’re loading it then inject? But then guess the pen will lock after 4 injections? Thanks

60 clicks is a full dose on each pen I think so 30 clicks would be half a dose yes. You only pull out what you need then inject as you will need to prime too. Did you get the 5mg pen without the golden dose? I’ve been reading they are pretty much all that’s available now!

we have forced 3 pens already with very very little difficulty so don’t worry about that. Or watch YouTube videos for extracting with an insulin needle and do that instead.

OP posts:
ByNiftyPombear · 14/06/2026 09:12

madeinthe80z · 14/06/2026 08:04

60 clicks is a full dose on each pen I think so 30 clicks would be half a dose yes. You only pull out what you need then inject as you will need to prime too. Did you get the 5mg pen without the golden dose? I’ve been reading they are pretty much all that’s available now!

we have forced 3 pens already with very very little difficulty so don’t worry about that. Or watch YouTube videos for extracting with an insulin needle and do that instead.

Thank you for this. It’s due to arrive today so I’ll have to see if it’s for the golden dose when it arrives. I did have an email saying the pens were changing so am expecting it! I’ll give it a go at forcing it or if not, do have needles as have done one golden dose and another to go of my current 2.5.

Izzydogmum · 14/06/2026 09:22

Morning all! Happy Sunday.

I went up to 5mg last weekend, felt the effects a little with loose bowels shall we say! Other than that no effects. (No golden dose pen doh!)
been stressed at work last 2 weeks so weight loss has slowed. -0.9lb last week and -0.6lb this week, but a loss is a loss!
doing swimming twice a week, Zumba and aqua aerobics too.
i know everyone’s reactions are different to going up a pen but I hope this helps some people’s worries about it.
off on hols this week but only Butlins! So let’s hope I still make good choices.

starting: 287lb
today: 270.9lb
jab 7 today.

hope you all have a good week!

suneetime · 14/06/2026 09:38

Weigh in day today and 3lb off this week. Delighted with that as only been 1lb last couple of weeks plus a previous 1lb gain so overall that brings me to 1 stone loss in 6 weeks. Only 3 stone to go!! Although I think I might be happy with 2. I’ll see when I get that far.

I have a desk job so really need to start exercising now. Any recommendations for easyish YouTubers to take a look at that I can do at home?

Boreded · 14/06/2026 09:48

suneetime · 14/06/2026 09:38

Weigh in day today and 3lb off this week. Delighted with that as only been 1lb last couple of weeks plus a previous 1lb gain so overall that brings me to 1 stone loss in 6 weeks. Only 3 stone to go!! Although I think I might be happy with 2. I’ll see when I get that far.

I have a desk job so really need to start exercising now. Any recommendations for easyish YouTubers to take a look at that I can do at home?

Really great job. You’ll be done by Christmas at this rate

Boreded · 14/06/2026 09:54

Izzydogmum · 14/06/2026 09:22

Morning all! Happy Sunday.

I went up to 5mg last weekend, felt the effects a little with loose bowels shall we say! Other than that no effects. (No golden dose pen doh!)
been stressed at work last 2 weeks so weight loss has slowed. -0.9lb last week and -0.6lb this week, but a loss is a loss!
doing swimming twice a week, Zumba and aqua aerobics too.
i know everyone’s reactions are different to going up a pen but I hope this helps some people’s worries about it.
off on hols this week but only Butlins! So let’s hope I still make good choices.

starting: 287lb
today: 270.9lb
jab 7 today.

hope you all have a good week!

I think I’m about to have one of those slower weeks too, I’m halfway through and down just .2, but I was throwing up last week so my usual 3-3.4 loss ended up being a 4.8 so it’s likely just rebounding because I’ve got more in my digestive system.

youve done a great job so far, we started not too far away from each other, keep sticking with it and this time next year we will both be celebrating hitting our targets (and maintaining them for a little while too hopefully)

TeamsThemeTune · 14/06/2026 10:46

Despite currently being 2 days late for my 5th jab, I woke up at 2am with tummy pain and a desperate need for a poo. Down 0.6kg this morning!!!

@Izzydogmum great losses!

Hillsmakeyoustrong · 14/06/2026 10:50

Hi all, no weigh in update as that happens on a Wednesday, but my period was delayed by about a week. I think its defo due to mounjaro. Will be interested to see if its heavier or lighter than usual...

Hillsmakeyoustrong · 14/06/2026 10:52

Everyone is doing great. I had a really good first loss week one and then it slowed in week two. Probably won't lose any this week as I retain so much water on a period. It's the long game!

NettleTea · 14/06/2026 11:12

Weigh in today and a loss of 1.2 kg / 2.6 lbs
still on 2.5 and 'officially' the end of my 2.5 pen, but due to golden dose I still have 2 more doses. My 5mg pen is coming this week and I plan to keep on 2.5 as its working for me. I have a referral code to use from someone, and I will suspend my prescription on Bolt and use that for the next pen, and see if Bolt will offer me anything to come back- I know some of them do, so Im keeping fingers crossed. Im still well over the BMI needed to access other clinics easily and have time in hand to look around, so will be looking at the monj site to see how the land lies

KittensAndCupcakes · 14/06/2026 19:20

So those of you who are on 5mg pen and just using 2.5 (with 30 clicks) or 3.75 (with 45 clicks), are you keeping your pens in the fridge? If that the way to stop it going off for over 30
days from opening? I’m sitting here thinking it’s a financial no brainer to take the 5mg pen next even if I stick with 2.5mg doses and it would then last two months. I mean that’s a hell of a saving!

Cece92 · 14/06/2026 19:21

I’m doing my 3rd jab in a bit. I’ve noticed even towards the end of the 7 days I’m not snacking think it’s a subconscious thing plus I try keep it low on jab day so I’m no in the loo. I’ve lost 7lbs in total over 2 weeks. Tomorrow if I’m not feeling too bad I might go for a swim in the morning and start doing this couple times a week xx

Popstarrrrr · 14/06/2026 20:26

4th 2.5 jab and weekly weigh in today.
SW 77kg
CW 74.4kg
GW 65kg

An increase of 0.2kg from last week. I think due to a couple of things. Have been moving less, not drinking enough water and also consuming more sugar. I'm hoping next Sunday I will have lost at least 0.6kg which would mean a total of half a stone in 4 weeks.

I've ordered the 5 pen but not sure I'm going to start it next Sunday as I have a lot of external work events that week and don't fancy doing them with a bad tummy. I've also ordered some insulin needles to extract my golden dose from the 2.5 pen.

madeinthe80z · 14/06/2026 20:40

What calories does everyone aim for? I aim not to go over 1600 per day and I take an average across the week but reading many posts on here, a lot of people seem to be aiming much lower. At my current 2.5mg dose I’d say 1500-1600 per day averaged across the week is all I can achieve at this dose. I feel like I’ll need to go up a dose to be able to reduce my calories further, which is what I’m thinking of doing with my next pen…

OP posts:
Hillsmakeyoustrong · 14/06/2026 20:55

Honestly @madeinthe80z I would say keeping the 1500 calories is a more healthy way to lose weight. Im hitting between 1400 and 1700 depending on how suppressed my appetite is and im making sure I don't fall lower than 1400.