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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

February 2026 starters

978 replies

Crossfitgirl · 30/01/2026 12:00

Hi all, I have my first pen on the way and as far as I can see there is no starter thread for Feb, so I hope it's ok to make one.
All welcome whether recently started or looking to start this month - I think by the time mine arrives it will probably be February!
Hoping for support, experiences, recommendations, more support and the rest!

I am nearly 40, 2 young kids and full time job, starting on wegovy, with the goal of lowering my cholesterol (and reducing my huge belly).

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12
Cookiedough123 · 24/02/2026 11:01

Morning. My final week 1 weigh in and I'm down a total of 6.4lbs so I’m really happy with that!
I have just had my 2nd jab which actually stung and bled this time.. not sure where I went wrong as I didn’t even feel the first one on my other leg. Hope everyone has a good day.

pelagra · 24/02/2026 11:21

@Cookiedough123 that's an amazing loss. If I recall, you want to drop 3 stone. You've just achieved over 15% of that.

Perserverancepayoffplease · 24/02/2026 18:20

I've just ordered my next pen. Have gone up to 5mg because I'm just not really losing much weight despite counting calories etc.

nightowlerine · 24/02/2026 19:37

Hi all can I join? I had my second dose of wegovy yesterday afternoon and feel really awful today, I am exhausted and quite nauseous with a headache that seems to come and go. Trying to drink plenty of water and hoping I feel better tomorrow. I have about 5st to lose so a way to go!

ASkarsMissus · 24/02/2026 20:04

Joining you all too. I started at the beginning of Feb on 2.5 Mounjaro. Had it in the fridge for 4 months before I plucked up the courage. Happy to say I have had no side effects at all though, apart from having bags more energy. It’s been amazing for me so far.

I’m menopausal and have insulin resistance so losing weight was not happening no matter what I did. Lost 3lb in week 1, nothing in week 2 and 3lb in week 3. Want to lose another 1.5-2 stone but playing by ear a bit as I don’t want to get too skinny. It’s arse or face at this age! 😂

Pinkchilli · 24/02/2026 20:16

nightowlerine · 24/02/2026 19:37

Hi all can I join? I had my second dose of wegovy yesterday afternoon and feel really awful today, I am exhausted and quite nauseous with a headache that seems to come and go. Trying to drink plenty of water and hoping I feel better tomorrow. I have about 5st to lose so a way to go!

Same here had my second dose Sunday 10pm and felt rotten all day. Nauseous and so tired all day to the point where it’s hard to keep eyes open 🫣

peppercornrent · 24/02/2026 20:54

I'm mounjaro rather than wegovy, but I found that I got fewer side effects taking it in the morning rather than evening, and after a reasonable breakfast.

Rainboat · 24/02/2026 21:55

Hi everyone, I just had my first mounjaro dose today. I’m a bit confused now, for the 1st dose, I set the dial to 1. So for the following weeks, is there dial 2/3/4? Or should I just set it to 1 again? Sorry, if it’s a silly question.

TwoNicePuppies · 24/02/2026 22:07

@Rainboat you just repeat the same thing each week, the 1 just refers to 1 dose. You take the same amount of medicine each of the 4 weeks that you use the pen.

Rainboat · 24/02/2026 22:11

TwoNicePuppies · 24/02/2026 22:07

@Rainboat you just repeat the same thing each week, the 1 just refers to 1 dose. You take the same amount of medicine each of the 4 weeks that you use the pen.

Thank you, so I just set to 1 again and use it for 2nd, 3rd and 4th dose, right?

Cookiedough123 · 24/02/2026 22:21

@pelagra thanks that’s a great way to look at it!

@Rainboat when you push the plunger down it goes back to 0 so each time you jab you will turn to 1 and it will then go back to 0 x

Rainboat · 24/02/2026 22:25

@Cookiedough123thank you clarifying!

nightowlerine · 25/02/2026 09:17

@Pinkchilli I didn’t expect it because I had no side effects at all last week. How are you feeling today? I woke up still with a slight headache but that has shifted now.

@peppercornrent thank you I will try this next week and see if it helps

Rosetime · 25/02/2026 11:33

Day 6 into my 1st dose. Next dose is tomorrow. I have noticed that the food noise started creeping back on Day 4.
Yesterday was the use of willpower and looks like today will be the same.

Pinkchilli · 25/02/2026 11:41

nightowlerine · 25/02/2026 09:17

@Pinkchilli I didn’t expect it because I had no side effects at all last week. How are you feeling today? I woke up still with a slight headache but that has shifted now.

@peppercornrent thank you I will try this next week and see if it helps

@nightowlerine yes I was the same and surprised as I felt ok first week! Fine today but queasy but able to function better 🤣

DanaScullysLegoHair · 25/02/2026 11:59

Hey all,

How are we all doing? I had my last 0.25 dose of Wegovy on Friday, 0.5 pen has arrived ready to take this week.

Wow, I have started my period now after days of spotting and it has absolutely WIPED me out. I have been tired since starting Wegovy which has actually been really helpful as I've had poor sleep for a long time. However, I've been waking up every morning since Sunday feeling utterly exhausted. I did wonder if it's a combo of period, WG and lower cals. I've been craving sweets and chocolate and have had some but within my calories.

I'm hoping to perk up before I take my firat dose of 0.5mg. My weight is back to 12st 7lb (10lb off in 4 weeks) and am waiting to see if it goes down a bit more when my period finishes.

Still happy to be on it, side effects have been minimal. Fingers crossed for the next dose.

Good luck everyone 🙂

Rosetime · 25/02/2026 14:49

@DanaScullysLegoHair , that's impressive weight loss. I think being on one's period with the WLI totally drains one. Hope the move to 0.5mg has minimal side effects.

DanaScullysLegoHair · 25/02/2026 17:33

Thank you @Rosetime, I don't doubt that for a second. At least I'll be prepared next month and the way it has fallen, I'll have 2 or 3 higher doses under my belt (hopefully) as peri is truly unpredictable!

I am very pleased with 10lbs off, my weight has been fluctuating by 3lbs almost daily over the last week. I know they say don't keep weighing but I'm genuinely interested in what is going on.

I do hope WG continues to be kind to me. The sunshine today has made me more determined to feel good in my skin by the time the 'proper' sunny days are here 👍

princesspeppax · 25/02/2026 19:46

Day 5 of first jab and starting to feel the hunger kicking in after having a non existent appetite for days. No side effects which i’m pleased about - is this the norm for every week for others ? I’m also slightly disappointed after seeing so many others loose in the first week to have weighed in and not lost. Depsite being incredibly strict below 1000 calories a day 😥 off on holiday in May and was hoping to have slimmed by then ! 😥

Rainboat · 25/02/2026 19:59

princesspeppax · 25/02/2026 19:46

Day 5 of first jab and starting to feel the hunger kicking in after having a non existent appetite for days. No side effects which i’m pleased about - is this the norm for every week for others ? I’m also slightly disappointed after seeing so many others loose in the first week to have weighed in and not lost. Depsite being incredibly strict below 1000 calories a day 😥 off on holiday in May and was hoping to have slimmed by then ! 😥

I took my first dose yesterday evening. When did you feel the food suppression? I was still a bit hungry today.

princesspeppax · 25/02/2026 20:18

Rainboat · 25/02/2026 19:59

I took my first dose yesterday evening. When did you feel the food suppression? I was still a bit hungry today.

Friday evening, after a big treat meal! Woke up Saturday morning and struggled to eat a thing that was the same up until today

starmoonsun · 25/02/2026 21:36

princesspeppax · 25/02/2026 19:46

Day 5 of first jab and starting to feel the hunger kicking in after having a non existent appetite for days. No side effects which i’m pleased about - is this the norm for every week for others ? I’m also slightly disappointed after seeing so many others loose in the first week to have weighed in and not lost. Depsite being incredibly strict below 1000 calories a day 😥 off on holiday in May and was hoping to have slimmed by then ! 😥

I didn't loose the first week despite hardly eating but on week 4 now and have lost about 11 pounds now so don't worry at this stage.

StatisticalStitches · 25/02/2026 21:43

First week weigh in this morning, lost 5.7lbs/2.6kg. Done 2nd jab tonight.

I was warned about my contraceptive pill not working properly but hadn't considered it would trigger a bleed, so that's an extra side effect for this week. For those on the mini pill, did it settle down after a few weeks?

soupmaker · 25/02/2026 21:56

End of week 2 for me, so third jab tomorrow.

Jumped on the scales tonight and am 15.1. So 3lbs lost this week. I’m feeling so much better. I’m eating less refined carbs and avoiding more than one glass of wine and it’s done wonders for my skin.

I’m still feeling the appetite suppression and making much better choices. I’m feeling full most of the time. Breakfast this morning was a slice of rye toast with butter and marmite - normally I’d do two slices - lunch was lentil soup and a kefir yoghurt - and I wasn’t starving at dinner time. I’m amazed. Also I just don’t feel the urge to snack after dinner. It’s weird.

Crossfitgirl · 25/02/2026 23:24

It's great to hear how everyone is doing. For those feeling nauseous / crap, has anyone tried electrolyte drinks? I've found a wegovy support group on Facebook and quite a few people seem to be taking those to help stay hydrated. I started with a bit of a headache today and I had a lucozade sport which I think has electrolytes for re-hydration, and I did feel better after.

I have completed my first month on 0.25, and have decided to stay on 0.25 for my next pen.

I haven't lost loads - about 3kg over 4 weeks (I think it's about half a stone?), but I think it's a healthy sustainable loss. I'm weighing daily, and watching patterns over the month rather than each week. I gained in week 3 and I felt shit about it, but actually overall the pattern is going downwards.

I seem to be getting good suppression through most of the week, but not so much that I can barely eat. It's just stopping me from snacking, and although I was still wanting sweet stuff last week my cravings have definitely subsided - I hope this due to having less therefore wanting less so that I can continue. Will power does seem so much easier and like I don't even have to think much about not eating the sweet things, so I'm pleased with that. It's strange!

So after nearly 4 weeks of Wegovy

SW: 66.6kg
CW: 63.2kg
GW: 57kg (ish)

Ooh and my body fat % has finally dropped to 39% from 40%! Much more pleased with this than the weight! That did not budge at all until today!!

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