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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

February 2026 starters

978 replies

Crossfitgirl · 30/01/2026 12:00

Hi all, I have my first pen on the way and as far as I can see there is no starter thread for Feb, so I hope it's ok to make one.
All welcome whether recently started or looking to start this month - I think by the time mine arrives it will probably be February!
Hoping for support, experiences, recommendations, more support and the rest!

I am nearly 40, 2 young kids and full time job, starting on wegovy, with the goal of lowering my cholesterol (and reducing my huge belly).

OP posts:
Thread gallery
12
StatisticalStitches · 21/02/2026 21:33

Thanks for sharing that graph @Crossfitgirl It's helped me understand why I feel so rubbish today. Thursday and Friday I felt fine, a small dip in appetite yesterday. I injected Wednesday evening and feel like I've been hit by a bus today. Nauseous, absolutely no appetite and wiped out so much so I've been in bed all afternoon. I made myself eat a few grapes this afternoon and two small Ritz crackers. I've managed to keep sipping water which is at least something. Hoping tomorrow is a better day 🤞

Rosetime · 21/02/2026 22:44

Thanks @Crossfitgirl .

Welcome to the group, Newcomers.

I took my first dose on Thursday. My tummy feels bubbly. Also feel a bit headchy, a bit nauseous and a bit impatient. I started my period on Thursday and I am a few days post-op. So not sure whether the way i feel is due to MJ or due to something else.

I will weigh-in on Thursday.

RIRO25 · 22/02/2026 08:52

Hello everyone I’m one my second week of 2.5mg MJ. Wow I have had a very bad upset tummy all week I’ve been totally wiped out. Provider (Voy) has told me to have a weeks break before taking third injection which is due today. Really annoyed. I hope the side effects do not happen again. 3kg so far which I’m happy about so I’m scared weight my go back up on my week break

princesspeppax · 22/02/2026 09:48

First dose 2.5mg on Friday evening, fully prepped myself with multiple of supplies in event of bad side effects. So far had nothing, but not hungry at all. Really struggling to eat anything, only managed one slice of brown toast all day yesterday which I know is not sustainable and will make me not well, is anyone finding the same?

Wambamaloomaawambamboo · 22/02/2026 11:03

I've taken my 3rd dose of 2.5mg mj a few days ago and feel absolutely nothing, no sides, no appetite suppression, nothing, huge contrast from week 1 & 2

Notellinganyone · 22/02/2026 11:43

Wambamaloomaawambamboo · 22/02/2026 11:03

I've taken my 3rd dose of 2.5mg mj a few days ago and feel absolutely nothing, no sides, no appetite suppression, nothing, huge contrast from week 1 & 2

That’s interesting. I’m three days into dose two, strong appetite suppression and lost 6lbs ( I only have 3stone to lose so a fair chunk). I’ll be interested to see what next week is like as I want to do another month on 2.5.

Theringcycle · 22/02/2026 19:42

Evening all. I’m 3 days into jab 3 and have been really tired today. My friends who are a few months in say they had a tired day each week at the start - hoping it goes away with time. Struggled to eat this evening - I think I’ll have a bit of a decision about whether to titrate up straightaway. I’m NHS-prescribed (diabetes) so will see what the Dr recommends as it may be that the increased dosages are better for glycaemic control. Is anyone else also using this to manage diabetes (as well as weight loss)?

smallsilvercloud · 22/02/2026 20:46

Just started today on wegovy at almost 15stone, I’ve put on a stone a year for the last 5 years! I didn’t want to turn to wli but with perimenopause my weight is just getting out of hand and cannot seem to lose it on my own, I want to get down to 10/11 stone, I’m 5ft 7. with spring fast approaching I’m getting nervous about less clothing to hide under so hoping by summer I’d shift 2 stone hopefully that’s doable. I swear already I’m not thinking about snacking!

Pinkchilli · 23/02/2026 09:35

2nd Wegovy jab last night. Bit disappointed as I’ve lost just under 3lbs the first week. I’ve been tracking calories approx 1400 per day ( which is 1000-700 deficit according to my Apple watch) and upping protein. I had cut my intake before wegovy so maybe that’s why I’ve not had a big loss. My side affects last week were ok bit of constipation. I do feel the suppression and have cut down snacking majorly. Will refocus for this week and see what that brings!!

wlinewbie26 · 23/02/2026 09:47

Morning all, I had just done my 3rd jab and I have lost 4.35kg so it’s gone well so far.

i had a short plateau but trusted the calorie counting process. I have a max calorie intake set at 1700 but tend to average 1500 with good protein intake.

I think MJ is def helping as I am not thinking about food.

Just a note - I thought I had done something wrong with my pen this morning as I seemed to have too much liquid left in my pen. I believe It is normal to have liquid to the last line of your pen making it look like another dose.

Wambamaloomaawambamboo · 23/02/2026 11:11

wlinewbie26 · 23/02/2026 09:47

Morning all, I had just done my 3rd jab and I have lost 4.35kg so it’s gone well so far.

i had a short plateau but trusted the calorie counting process. I have a max calorie intake set at 1700 but tend to average 1500 with good protein intake.

I think MJ is def helping as I am not thinking about food.

Just a note - I thought I had done something wrong with my pen this morning as I seemed to have too much liquid left in my pen. I believe It is normal to have liquid to the last line of your pen making it look like another dose.

Yes people call thaf the golden dose, shouldn't be used but people do use it as a 5th dose

pelagra · 23/02/2026 13:13

Wambamaloomaawambamboo · 22/02/2026 11:03

I've taken my 3rd dose of 2.5mg mj a few days ago and feel absolutely nothing, no sides, no appetite suppression, nothing, huge contrast from week 1 & 2

We seem to be having similar experiences.

I think I might be getting a bit of suppression, as I'm less inclined to snack in the evenings, but I also have a cold with a horrible sore throat, so it may be that.

5 pounds down anyway, but that is mainly due to meal planning and willpower.

I'm normally quite sensitive to medications, so I'd expected to feel some impact on the lowest dose, and hoped not to have to go up very high. I bought a package deal of 0.25 and 0.5 pens, and had been wondering if I'd made a mistake and might want to stay on the lowest dose for two months. Now I think the sooner I can increase the better.

Wambamaloomaawambamboo · 23/02/2026 13:18

pelagra · 23/02/2026 13:13

We seem to be having similar experiences.

I think I might be getting a bit of suppression, as I'm less inclined to snack in the evenings, but I also have a cold with a horrible sore throat, so it may be that.

5 pounds down anyway, but that is mainly due to meal planning and willpower.

I'm normally quite sensitive to medications, so I'd expected to feel some impact on the lowest dose, and hoped not to have to go up very high. I bought a package deal of 0.25 and 0.5 pens, and had been wondering if I'd made a mistake and might want to stay on the lowest dose for two months. Now I think the sooner I can increase the better.

Yeah I'm using willpower just now! I do take quite well to medication ie Tramadol does absolutely nothing for me 😂 so i should have expected this. I have ordered 5mg for my next pen

peppercornrent · 23/02/2026 13:56

Wambamaloomaawambamboo · 23/02/2026 11:11

Yes people call thaf the golden dose, shouldn't be used but people do use it as a 5th dose

What makes you think that it 'shouldn't be used'? Genuine question, but however I word it sounds snippy!

JenMum03 · 23/02/2026 14:00

Hi all... im wanting to start again, is there still a thread for discount codes?

Wambamaloomaawambamboo · 23/02/2026 14:03

peppercornrent · 23/02/2026 13:56

What makes you think that it 'shouldn't be used'? Genuine question, but however I word it sounds snippy!

Haha!
Well the pen is prescribed for 4 doses not 5. And you don't know how much of the medication your getting.

Why the '5th Dose' is unsafe
The Mounjaro “5th dose” is unsafe because it’s not designed to be given as a dose. As some liquid is lost every time you prime the KwikPen device, there is not always the same amount of liquid left after you’ve given yourself the standard 4 Mounjaro doses.

This means you do not know how much liquid you’re administering with the “golden dose”, which also means you do not know how much Mounjaro you’re getting.

If you’re using the “5th dose” to replace a standard Mounjaro dose, this may mean you’re getting a much smaller dose than you should be. This can interfere with your dosing schedule and may worsen side effects if you take the “5th dose” before stepping up to the next Mounjaro dose.

You may also take too much Mounjaro if you take the “golden dose” on top of your standard dose, which can also worsen side effects like feeling sick (nausea), being sick (vomiting), constipation, or diarrhoea.

Mounjaro should always be taken as described by the manufacturer in the patient information leaflet and user manual.

Mounjaro KwikPen 2.5mg solution for injection in pre-filled pen - User Manual - (emc) | 15481

Mounjaro KwikPen 2.5mg solution for injection in pre-filled pen - User Manual by Eli Lilly and Company Limited

https://www.medicines.org.uk/emc/product/15481/usermanual

Diddlydoowap · 23/02/2026 16:00

So I'm on day 4 and I'm not sure if I'm noticing an effect or trying really hard to find one! Still no tummy issues (hurray!) but I am finding it easier to not reach for a biscuit or chocolate. I have such a sweet tooth normally, so to get to 4pm with zero treats is unheard of! My appetite is not diminished though and I can still eat normal portion sizes, but given my weakness is sweet treats there's definitely a positive change!

Diddlydoowap · 23/02/2026 16:02

And call me reckless but I don't think I'd hesitate to use the 'golden dose' for week 5 given how expensive this stuff is!

Tovetov · 23/02/2026 17:25

@Wambamaloomaawambamboo we do know how much mounjaro 'golden dose' we are injecting. The syringes we use to extract the liquid have markings, obviously!

peppercornrent · 23/02/2026 17:26

But I do know how much I am taking - I draw 0.6ml with a syringe and dose on the appropriate day. Just randomly injecting the remainder of the pen would be madness! Initially it was possible to 'click' the correct dose, but can't seem to do that now.

Using the 5th dose significantly lowers costs.

Wambamaloomaawambamboo · 23/02/2026 17:40

Tovetov · 23/02/2026 17:25

@Wambamaloomaawambamboo we do know how much mounjaro 'golden dose' we are injecting. The syringes we use to extract the liquid have markings, obviously!

Okay calm down! I'm just going with what it says online, obviously

Cookiedough123 · 23/02/2026 20:22

Hello! My 2nd jab is due tomorrow! Week one has been great. No major side effects and a 5.5lb loss as of this morning. I’m kind of calorie counting by making sure I don’t eat too much and weighing stuff when I’m not sure but I’ve mainly cut out snacking between meals so haven’t had chocolate, crisps, cakes etc. Luckily it’s felt easy to cut it out! I’m also only eating 2 meals a day. I’ve been looking into golden dosing but have also heard some pens don’t have it in anymore.

starmoonsun · 23/02/2026 21:11

princesspeppax · 22/02/2026 09:48

First dose 2.5mg on Friday evening, fully prepped myself with multiple of supplies in event of bad side effects. So far had nothing, but not hungry at all. Really struggling to eat anything, only managed one slice of brown toast all day yesterday which I know is not sustainable and will make me not well, is anyone finding the same?

It took me a while to work out what to eat. As I wasn't hungry and couldn't be bothered to make anything proper, but knew I needed to eat something so ate lots of toast which wasn't good. Things like boiled eggs, scrambled eggs, crackers and ham/ cheese with cucumber, greek yogurt and fruit I found good as quick and easy to make but easy to make a smaller portion.
Week 4 now and I'm getting used to it but that might be because suppression no where near as strong as it was at the beginning. Hoping it returns when I increase to 5mg next week as had a few biscuits and chocolats this week which I wasn't interested in at all at first. Even though I've eaten better this week that any other week since I started.

fedupandtired1 · 23/02/2026 21:23

I’m really wanting to try wegovy I noticed voy had a good plan. I’m really worried about long term side effect down the line , reality is though I need to lose 3-4 stone and my osteoarthritis in my knees no thanks to my current weight . I’m a nurse and a busy mum and I can hardly walk

Notellinganyone · 23/02/2026 22:10

It’s really weird. I’m in day ten after first jab and felt hungry and normal for the first time today. It’s as though someone flicked a switch. Currently v peckish but holding off. Due to take jab 3 of 2.5 mg on Thursday. Was hoping to stay on 2.5 for another month but not sure now…

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