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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Brand new January 2026 starters

1000 replies

BG2015 · 26/12/2025 11:58

Hi, my first WG pen is in the fridge ready to start on 1st January.

Im 56 (57 in Feb) post menopausal and cancer survivor in remission 5 years nearly. still taking cancer prevention medication that I believe that is hindering my weight loss. I just can't seem to lose it no matter how much I try. It took me 5 months to lose 10lb earlier on in the year.

Im 5' 8" so carry my extra weight well.
CW 13stone
TW 11 stone

Whose joining me on this weight loss journey?

OP posts:
Thread gallery
11
Alltheyellowbirds · 14/01/2026 20:29

BG2015 · 14/01/2026 20:12

@goldylockthis is how I feel. I don't like the unpredictability of how I feel each day. I'm going to stick with it for another dose which will be 0.5 and see how I feel. I've got it at a discount so at least I'm not paying full price.

I think you need to give it some time so your brain can get used to that. I think we’re all going to have to make some uncomfortable mental shifts if we want to see a permanent change in our eating habits and our weight. Please don’t give up just yet x

sunnysunshinebear · 14/01/2026 21:44

Third injection for me today! Agree with others who are hungry on their jab day!! It’s been working well until today. Yesterday I started to feel a bit more hungry and today I can eat a lot more! Hoping the third kicks in soon!

Ralphiesaurus · 15/01/2026 06:14

Did my second jab yesterday. All good. Was beginning to wear off by the day betore. I weighed during the week and seemed to have lost a bit, but then when I weighed yesterday it looked like I had STS. My body can be weird when I lose weight though… seemingly nothing for ages and then chunks!! Will post stats once I have a couple of consistent readings.

notcomfortable · 15/01/2026 06:19

Another cheeky weigh in this morning and I've lost another kg!! 🥳

bec81 · 15/01/2026 07:02

Second jab last night. Was feeling like I was going to puke in the gym this morning. First time I felt that, quite uncomfortable

recruitretain · 15/01/2026 07:03

So here I am:

About to book to see my pharmacist today to start my Monjaro journey, in 50, just under 6 foot and sadly 330 pounds, I feel depressed and sick I have let this happen, it has stopped me enjoying life
I have avoided parties, trips, family time because I’m so so embarrassed by my weight, I have felt suicidal at times, and once was so embarrassed about needing a seat belt extension on a flight home I missed the flight and spend 3 days traveling by bus and rail, that’s messed up.

But I have had enough and I want to enjoy my kids and I want to stop my life being destroyed by being Fat

Please tell me I’m making the right steps

And please help me with tips on how to succeed

mendandmakedo · 15/01/2026 07:20

notcomfortable · 15/01/2026 06:19

Another cheeky weigh in this morning and I've lost another kg!! 🥳

Well done! That's great.

FrostyFlo · 15/01/2026 07:20

recruitretain · 15/01/2026 07:03

So here I am:

About to book to see my pharmacist today to start my Monjaro journey, in 50, just under 6 foot and sadly 330 pounds, I feel depressed and sick I have let this happen, it has stopped me enjoying life
I have avoided parties, trips, family time because I’m so so embarrassed by my weight, I have felt suicidal at times, and once was so embarrassed about needing a seat belt extension on a flight home I missed the flight and spend 3 days traveling by bus and rail, that’s messed up.

But I have had enough and I want to enjoy my kids and I want to stop my life being destroyed by being Fat

Please tell me I’m making the right steps

And please help me with tips on how to succeed

I'm with you . I filled in my form on 2/1 and got on the scales after about two years of ignoring them to see 247lbs . That in itself was a big shock so from that date I really cut down . My pen arrived in Friday and I did my first jab within 30 minutes of arrival .
It switches everything off and I eat just because you need to .
Got on the scales a couple of days ago , so about day 4 of the jab , but a week before that in cutting down to find I'm 16lbs down . I'm amazed . We can do this !

mendandmakedo · 15/01/2026 07:23

recruitretain · 15/01/2026 07:03

So here I am:

About to book to see my pharmacist today to start my Monjaro journey, in 50, just under 6 foot and sadly 330 pounds, I feel depressed and sick I have let this happen, it has stopped me enjoying life
I have avoided parties, trips, family time because I’m so so embarrassed by my weight, I have felt suicidal at times, and once was so embarrassed about needing a seat belt extension on a flight home I missed the flight and spend 3 days traveling by bus and rail, that’s messed up.

But I have had enough and I want to enjoy my kids and I want to stop my life being destroyed by being Fat

Please tell me I’m making the right steps

And please help me with tips on how to succeed

I am only towards the end of my first week. It has been life changing so far for me. I have not regretted it.

That sounds really tough about the travelling. With all the successes everyone had had on this medication there's no reason why that cannot also happen for you as well.

recruitretain · 15/01/2026 07:24

FrostyFlo · 15/01/2026 07:20

I'm with you . I filled in my form on 2/1 and got on the scales after about two years of ignoring them to see 247lbs . That in itself was a big shock so from that date I really cut down . My pen arrived in Friday and I did my first jab within 30 minutes of arrival .
It switches everything off and I eat just because you need to .
Got on the scales a couple of days ago , so about day 4 of the jab , but a week before that in cutting down to find I'm 16lbs down . I'm amazed . We can do this !

Wow that’s amazing story thank you for the support

Dewberrywotsit · 15/01/2026 07:27

So, on 2nd jab day 5. I am considering putting the next jab off for a few days at least if not a week because I have a horrible bladder feeling as though I have cycstitis (which I have had loads of times in the past) BUT it is not cystitis. It isn;t escalating like my cystitis does. I am drinking gallons of water and have done consistently and I am up weeing all night getting exhausted. It actually started in my first week but got better after the first few days following jab and I hoped for same again...but this time it has got worse and it is very uncomfortable. I have no other typical symptoms. No burning and no temperature/shivers. I know it is the MJ. If it doesn't ware off today I will pop into the chemist who perscribed my MJ for me as she said I can come in any time. I googled it and there are a LOT of people experiencing this on MJ. I am hoping a break will sort it out and I can continue... ALSO woke up with severe tummy pain...but it was solved with an omeprazole - could that have been because I ate tuna pasta mayo? Maybe a bit too fatty?

notcomfortable · 15/01/2026 07:29

recruitretain · 15/01/2026 07:03

So here I am:

About to book to see my pharmacist today to start my Monjaro journey, in 50, just under 6 foot and sadly 330 pounds, I feel depressed and sick I have let this happen, it has stopped me enjoying life
I have avoided parties, trips, family time because I’m so so embarrassed by my weight, I have felt suicidal at times, and once was so embarrassed about needing a seat belt extension on a flight home I missed the flight and spend 3 days traveling by bus and rail, that’s messed up.

But I have had enough and I want to enjoy my kids and I want to stop my life being destroyed by being Fat

Please tell me I’m making the right steps

And please help me with tips on how to succeed

Welcome
The first step is terrifying. I was first on mj last March, I wasn't sure I was making the right choice but managed to lose 30kg. It really is a life changing medication.
Stick with it, even if you get side effects to begin with as they should definitely wear off. Stick with it even if you still feel hungry

notcomfortable · 15/01/2026 07:31

Dewberrywotsit · 15/01/2026 07:27

So, on 2nd jab day 5. I am considering putting the next jab off for a few days at least if not a week because I have a horrible bladder feeling as though I have cycstitis (which I have had loads of times in the past) BUT it is not cystitis. It isn;t escalating like my cystitis does. I am drinking gallons of water and have done consistently and I am up weeing all night getting exhausted. It actually started in my first week but got better after the first few days following jab and I hoped for same again...but this time it has got worse and it is very uncomfortable. I have no other typical symptoms. No burning and no temperature/shivers. I know it is the MJ. If it doesn't ware off today I will pop into the chemist who perscribed my MJ for me as she said I can come in any time. I googled it and there are a LOT of people experiencing this on MJ. I am hoping a break will sort it out and I can continue... ALSO woke up with severe tummy pain...but it was solved with an omeprazole - could that have been because I ate tuna pasta mayo? Maybe a bit too fatty?

Very stupid question as I have no experience of cystitis, could it be because you are drinking more?
I'm definitely peeing more

recruitretain · 15/01/2026 07:37

notcomfortable · 15/01/2026 07:29

Welcome
The first step is terrifying. I was first on mj last March, I wasn't sure I was making the right choice but managed to lose 30kg. It really is a life changing medication.
Stick with it, even if you get side effects to begin with as they should definitely wear off. Stick with it even if you still feel hungry

Thank you

Dewberrywotsit · 15/01/2026 07:57

notcomfortable · 15/01/2026 07:31

Very stupid question as I have no experience of cystitis, could it be because you are drinking more?
I'm definitely peeing more

Not stupid and I would assume it was that if it was just increased frequency, but it is also increased feeling of pressure/tightness/uncomfortable sensation in bladder and sometimes despite having drunk a LOT and having clear emissions (!) will go and almost nothing emerges...so I think there's something else going on. I wonder if it will be added as a side effect at some point as there are quite a lot of other people on the interweb mentioning it :) hence I am not really worried....but also don't enjoy it much and I am knackered whereas I was sleeping well to begin :/shame as otherwise it is great. I went to the gym yesterday and had. the most energy I have had for ages (until I conked out shortly after on sofa!)

Whatstfpoint · 15/01/2026 08:19

@recruitretain im a bit shorter but similar weight. Even on this thread I feel like a special case. It also brings home what a long journey it's going to be. I will probably need two years.

recruitretain · 15/01/2026 08:27

Whatstfpoint · 15/01/2026 08:19

@recruitretain im a bit shorter but similar weight. Even on this thread I feel like a special case. It also brings home what a long journey it's going to be. I will probably need two years.

I’m not in a rush just want to be successful

time hopefully will help me re-evaluate my food relationships and life goals

I’m just tired of being obese

feel free to send me a DM be good to discuss and keep tabs

ChilledProsecco · 15/01/2026 08:29

1st injection last night, weight 73kg this morning - here goes!!!

I’m not feeling any different so far, but that might be a good thing in terms of side effects!

Going to run after work. Have meals planned out.

So hoping this is the start of something positive……

YellowStockings · 15/01/2026 08:35

Morning! On day 5 of WG jab two here. Still figuring out how I feel about it - the first week I had a few days of feeling sick and struggling to eat properly (and lost over 2kg, yay), but this week I’ve felt basically normal. Which in many ways is better than the awful nausea, but it also means I’m hungrier! So far this week I’ve lost 0.2kg - quite a slow down!

Trying to just stick to smaller portions of healthy food, but it’s feeling a bit more like a regular diet this week if that makes sense? Though I am definitely getting fuller faster, and finding it much easier to resist unhealthy food (could just be placebo but I’ll take it).

Think I’ll jab on Saturday rather than Sunday this week, I think I probably just need to go up to the next dose in a couple of weeks?

The other thing I’ve wondered is I’m premenstrual this week, so often feel hungrier and more bloated anyway.

YellowStockings · 15/01/2026 08:37

Whatstfpoint · 15/01/2026 08:19

@recruitretain im a bit shorter but similar weight. Even on this thread I feel like a special case. It also brings home what a long journey it's going to be. I will probably need two years.

I hear you. By the sounds of it I’m not quite as heavy as you are, but I need to lose 30kg / around 5st. My goal weight is higher than some people’s start weights!

intentionals · 15/01/2026 08:46

Day five post second jab…definitely felt hungrier this week. Although it’s more like I recognise the feeling of hunger in my stomach and I have to think about it to determine if I am hungry.

went out for dinner for the first time last night - had a chicken salad which filled me up. My friend had a chocolate mousse dessert and it looked lovely but I was full from the salad (never been a thing for me before!) and didn’t want any.

weightless I think will be about one pound this week (weigh in tomorrow) - broadly because I haven’t been dashing to the loo all week!

Whatstfpoint · 15/01/2026 09:40

YellowStockings · 15/01/2026 08:37

I hear you. By the sounds of it I’m not quite as heavy as you are, but I need to lose 30kg / around 5st. My goal weight is higher than some people’s start weights!

Yeah. When I see a SW of 85kg I think 'what's the problem' but I remember that I felt fat too when I weighed 'just that' and was already well into yoyo-ing.

Whatstfpoint · 15/01/2026 09:44

recruitretain · 15/01/2026 08:27

I’m not in a rush just want to be successful

time hopefully will help me re-evaluate my food relationships and life goals

I’m just tired of being obese

feel free to send me a DM be good to discuss and keep tabs

Yes, at least there will be a lot of time to make changes. It's week 3 and im still figuring out my meal composition, timing and portion size. That alone will take me months.

CatNoBag · 15/01/2026 10:27

recruitretain · 15/01/2026 07:03

So here I am:

About to book to see my pharmacist today to start my Monjaro journey, in 50, just under 6 foot and sadly 330 pounds, I feel depressed and sick I have let this happen, it has stopped me enjoying life
I have avoided parties, trips, family time because I’m so so embarrassed by my weight, I have felt suicidal at times, and once was so embarrassed about needing a seat belt extension on a flight home I missed the flight and spend 3 days traveling by bus and rail, that’s messed up.

But I have had enough and I want to enjoy my kids and I want to stop my life being destroyed by being Fat

Please tell me I’m making the right steps

And please help me with tips on how to succeed

Good luck with your appointment today - if it works for you, I bet that even a few weeks in you'll start feeling so much better xx

Aimingdown · 15/01/2026 12:47

Hi all,
Another poster dropping by from the Jan 25 start group to wish you well.
MJ is a miracle drug as far as I’m concerned, there are wobbles, doubts, moments and plateaus but overall I (along with I think pretty much everybody on that thread) feel and look so much better than we did a year ago. Some of us are on to maintenance, some of us are still on the losing journey, it’s not a race and we all have different stories.
The support and info on the starters group is great, you will also learn many random facts about each other along the way and it really feels like being part of a group of friends.

A little bit of advice, take a full length photo or two now even if you hate it, hide it away and bring it out later for comparison. Many of us are finding that we don’t have a ‘good’ before photo to compare as we’ve been so camera shy in the past. Also eat protein and fibre!

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