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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Nov 25 starters - thread 2 - the one where we don’t eat everything in sight this Christmas!

994 replies

Springbaby2023 · 20/12/2025 23:16

Hi everyone, starting a second thread as the other one is almost full. We made it through month one, now here’s to a happy, healthy and lighter 2026!

OP posts:
Thread gallery
11
Midnightsummer · 31/12/2025 15:25

@SexyFrenchDepression Im in the exact same boat as you. I ordered 5mg on my last week of 2.5mg. I’m 2 days into the 5mg and omg the nausea is insane. I can’t even drink my protein shakes as they make me sick. I’ve managed to drink here and there and eat a little but I was just wondering if I wanted to reduce dose back to 2.5mg or the 3.75mg how do I do it on a full pen? And how has increasing to 3.75mg affected your weight loss so far?

SexyFrenchDepression · 31/12/2025 15:34

Midnightsummer · 31/12/2025 15:25

@SexyFrenchDepression Im in the exact same boat as you. I ordered 5mg on my last week of 2.5mg. I’m 2 days into the 5mg and omg the nausea is insane. I can’t even drink my protein shakes as they make me sick. I’ve managed to drink here and there and eat a little but I was just wondering if I wanted to reduce dose back to 2.5mg or the 3.75mg how do I do it on a full pen? And how has increasing to 3.75mg affected your weight loss so far?

I had to switch to clear whey rather than the milky stuff as couldnt stomach it, I love the clear whey flavours a lot more.

I do 45 clicks of the 5mg pen for 3.75mg, it would be 30 clicks for 2.5mg.

My weightloss per week is:

SW 12 stone
2.5mg
Week 1 -5.73lb
Week 2 -2.21lb
Week 3 -2.32lb
Week 4 - 3.2lb
Week 5 -2.98lb
3.75mg
Week 6 - 2.09lb
Week 7 - 1.98lb
Week 8 - 1.44lb
Total loss 22.4lb (incl to half way through week 9)
CW 10st 5.6 BMI 25.0
TW 9 st

So its been less loss per week but I imagine it is as expected after such quick loss to start with. The last week went up to the 27th Dec. I am not sure it actually is making any difference TBH however I will probably stick with it as it gives me somewhere to go downwards when I have reached goal I guess.

user593 · 31/12/2025 16:33

I went from 2.5mg to 45 clicks of a 5mg pen (3.75mg) on my last dose and I haven’t found the side effects too bad. I didn’t want to jump straight to 5mg. I’d definitely try 3.75mg @Midnightsummer!

TaffyTabby · 31/12/2025 20:09

Sigh my weight has been static for ten days. I guess to be expected with Christmas.
I didn’t eat that well today either though - too much cake lying around.
Need to sort myself out as otherwise it feels like a waste of the medication.
I’m going to take 3.75mg a day early tomorrow, then got another 3.75mg next week before I move up to 5mg.

StealthMama · 31/12/2025 20:10

Hi could anyone remind me how to get the golden dose? Ive got plenty of needle attachments but the pens won’t twist ant anll and I can’t remember how people were accessing this extra dose.

I’ve had on/off symptoms with the 5mg as well, so I might reduce to 3.75 next week as I up the exercise and see how that goes. nausea at the beginning of the week but also the tiredness I’m really struggling with.

TaffyTabby · 31/12/2025 20:23

@StealthMama i think it often won’t twist again once you’ve done the four standard doses, so people use a needle and syringe (very small needle, called “diabetic” needles) to piece the seal and pull out the dose. So it’s different to the needles you attach to the pen.

StealthMama · 31/12/2025 21:16

TaffyTabby · 31/12/2025 20:23

@StealthMama i think it often won’t twist again once you’ve done the four standard doses, so people use a needle and syringe (very small needle, called “diabetic” needles) to piece the seal and pull out the dose. So it’s different to the needles you attach to the pen.

Ah I see thankyou I’d thought I’d read something like that. Such a waste!

EducatingRosemary · 31/12/2025 22:42

Dosage question as getting paranoid I think!
My jab is due tomorrow and I’ve used up my 2.5mg pens. I now only have a 5mg pen. I don’t want to go up yet. Can I just confirm that taking half the dose from a 5mg pen gives exactly the same as a normal dose from a 2.5mg pen?

Also is it best to count clicks (is that easy to do?) or use the syringe needles I bought for the golden doses?

Thank you! Don’t want to screw this up.

SexyFrenchDepression · 01/01/2026 01:04

EducatingRosemary · 31/12/2025 22:42

Dosage question as getting paranoid I think!
My jab is due tomorrow and I’ve used up my 2.5mg pens. I now only have a 5mg pen. I don’t want to go up yet. Can I just confirm that taking half the dose from a 5mg pen gives exactly the same as a normal dose from a 2.5mg pen?

Also is it best to count clicks (is that easy to do?) or use the syringe needles I bought for the golden doses?

Thank you! Don’t want to screw this up.

Counting clicks is easy, 30 clicks for 2.5mg from 5mg oen, 3.75mg is 45 clicks. I only use the insulin needles for the golden dose.

SexyFrenchDepression · 01/01/2026 01:05

StealthMama · 31/12/2025 20:10

Hi could anyone remind me how to get the golden dose? Ive got plenty of needle attachments but the pens won’t twist ant anll and I can’t remember how people were accessing this extra dose.

I’ve had on/off symptoms with the 5mg as well, so I might reduce to 3.75 next week as I up the exercise and see how that goes. nausea at the beginning of the week but also the tiredness I’m really struggling with.

Edited

You should be able to get them from pharmacies. There are lots online with quick delivery also. I was worried when I did it the first time but it was so easy. 0.6ml for a full dose, often there is about 0.8ml left in the pen.

66babe · 01/01/2026 18:34

I’ve just done my next 3.75 , thinking of doing 5mg next week so will need to start thinking about getting my next pen , will stick to 5mg as I’ve done 2 x 3.75 and just moving up next week, how to find out where the best offers are ? It’s a minefield and most of them advertise discounts but then you have to do full consultation and find they offering a fiver off , I hate they take the money first and then I’ll have all the rigmarole of more pictures , videos and ID , puts you off shopping around but just so expensive as you move up .
Total 1 stone 4 lbs lost so far

SexyFrenchDepression · 01/01/2026 19:29

66babe · 01/01/2026 18:34

I’ve just done my next 3.75 , thinking of doing 5mg next week so will need to start thinking about getting my next pen , will stick to 5mg as I’ve done 2 x 3.75 and just moving up next week, how to find out where the best offers are ? It’s a minefield and most of them advertise discounts but then you have to do full consultation and find they offering a fiver off , I hate they take the money first and then I’ll have all the rigmarole of more pictures , videos and ID , puts you off shopping around but just so expensive as you move up .
Total 1 stone 4 lbs lost so far

https://monj.co.uk/discount-mounjaro-price-list/

This is a good site. My sons girlfriend just got her 1st 2.5mg pen from Pharmacy2u for under £100. Bolt have really good deals often also. It can be a faff with new photos but now you have already bought some it shouldn't be so tricky to buy more. I had some issues getting approved to start with but its been easy since. My BMI was juat over 25 getting my last pen and it was approved immediately. I am hoping it continues to be so easy once within healthy BMI range.

Monj - Pharmacy Info | All Discounts List

Monj - Unbiased Pharmacy Info (Discount Cost) List

https://monj.co.uk/discount-mounjaro-price-list/

butternut123 · 01/01/2026 23:05

@JustBeachthere are lots of maintenance providers. I plan to move across to Cloud next one (I think that will be my last one before teaching goal weight) and they offer a good maintenance plan where you just have to order from them within a two year period. My plan is to go cold turkey and then order pens if (when) my weight fluctuates again. Never really weighed myself before so going to keep on weekly weigh in to monitor from then on.

tobee · 02/01/2026 00:37

First time since starting mounjaro I picked a bit at leftovers. I had my normal yogurt and nuts type breakfast. Had a small portion of family dinner. But went into the kitchen later and ate a few potatoes out of the fridge. Wasn't even hungry, hadn't been thinking about food, I just did it!

I don't know probably reading too much into it. It's not like I've been eating endless crisps, nuts and chocolates like Christmas normally. I'm kind of looking forward to next Monday, starting my second month of 5mg, the first jab of the new year where I'll be able to assess better how this dose is working. Christmas is too confusing!!

diggitydoo · 02/01/2026 09:06

I’ve had two 3.75 and a 5 dose out of a 5 pen. Can anyone work out how many more 5 doses are left?

TaffyTabby · 02/01/2026 09:59

I’ve been more picky too @tobee
not sure if it means it’s not working as well or if maybe psychologically I’m getting complacent

@diggitydoo if the pen has the golden dose then total volume will be just over 25mg, and you’ve used 8.75mg so there should be 16.25mg left. So three doses of five with a little bit extra remaining.

I would do 5mg, 5mg, and then if you’re finding that okay you could do whatever is left in one dose which will probs be 6-7mg.

I had read somewhere they’re going to stop producing pens that have the extra dose in, but I’m yet to hear of it actually happening.

user593 · 02/01/2026 10:59

I’m due my sixth dose on Sunday and my weight loss has picked up a bit 🙏 after stagnating for 1-2 weeks. I seem to need to eat a lot of chickpeas to keep things moving! Now 32.5lbs down in 39 days.

Happy New Year all! 🥳

SexyFrenchDepression · 02/01/2026 11:03

diggitydoo · 02/01/2026 09:06

I’ve had two 3.75 and a 5 dose out of a 5 pen. Can anyone work out how many more 5 doses are left?

Edited

2 x 3.75 = 7.5mg plus 1 x 5mg = 12.5mg used so far? Probably about 26mg in total in the pen so you would be left with around 13.5mg in the pen. It usually works that you can have 3 x 3.75mg doses then 3 x 5mg out of 1 5mg pen in total.

tobee · 02/01/2026 16:57

Yay! I was just going to suggest you ask @SexyFrenchDepression , she can do maths!! And she's gone and done it already! @diggitydoo 😀

TaffyTabby · 02/01/2026 17:06

Doh didn’t read the question properly- classic!

SexyFrenchDepression · 02/01/2026 17:52

tobee · 02/01/2026 16:57

Yay! I was just going to suggest you ask @SexyFrenchDepression , she can do maths!! And she's gone and done it already! @diggitydoo 😀

Haha, I have a little tab on my weightloss spreadsheet where I have calculated all the possibilities for each pen 😂

SexyFrenchDepression · 02/01/2026 17:56

I have this horrible virus at the moment, I had my jab as normal yesterday as thought if I am feeling rubbish then just as well get through my worst days on the jab whilst I am laid up anyway.

Feeling so tired but I am sure its the virus as been feeling ok this last 2 jabs, also due on which makes me so ill anyway.

Other than eating more fibre my other new years resolution needs to be to see the doctor re potential peri menopause. My periods are getting worse and worse (since before mj) so definitely worth a chat! Dont want to feel like this every month.

user593 · 02/01/2026 19:38

@SexyFrenchDepression We’ve had the virus twice in our household. It’s not so bad the second time though. I hope you feel better soon! In my experience it tends to linger.

I’ve found eating chickpeas really good for fibre intake, but you have to like chickpeas 😅

SexyFrenchDepression · 02/01/2026 19:46

user593 · 02/01/2026 19:38

@SexyFrenchDepression We’ve had the virus twice in our household. It’s not so bad the second time though. I hope you feel better soon! In my experience it tends to linger.

I’ve found eating chickpeas really good for fibre intake, but you have to like chickpeas 😅

I had a similar thing in March but was so ill I had to have a month off work, I havent had a month off work in total for the 20+ years prior to that! Hoping it doesn't last too long but my dad is on week 3 so far.

I could probably eat chickpeas but no one else in my house would!

EducatingRosemary · 02/01/2026 23:35

Just done my 11th jab and successfully managed to do my first click counting to get a 2.5 dose from the new 5mg pen. Thanks to those who advised me on this 💐

Total loss 2 stone 4lbs (14.3kgs). Feeling flipin’great. Wish I’d started sooner. MJ is amazing. I have 4lbs more to lose to move out of the overweight BMI zone.

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