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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro July 2025 Starters

1000 replies

daisydreamies · 27/06/2025 14:17

Please let me know if there's already a thread for this! I did have a look and couldn't find anything.

I've just been approved for Mounjaro from Asda. I've been trying to lose weight for seven years. I've tried calorie counting, intermittent fasting, Slimfast, Weight Watchers (it didn't work for me, I was so hungry all the time and ended up overeating so I never lost), and Slimming World (I enjoyed it, but the weight loss for me was too slow so I ended up stopping as it's so expensive). The most successful diet I've been on was when I was breastfeeding my son, but the weight came back on when I stopped. I'm still lighter than I was pre-pregnancy, but this weight is not shifting or if it does it's so slow and I lose the motivation. I tried most for about 4-6 months (except WW, I gave that up after 2).

I can't exercise as I have a chronic illness, so I'm often in pain from just existing and exercise just cripples me. I think I have PCOS too, which might be why I'm struggling so much to shift the weight with diet alone.

My goal is to lose weight with Mounjaro hopefully, and then follow a Slimming World style diet after (which I still kind of follow now, just not as strict). I've managed to maintain my current weight for a year so I'm pretty confident I can maintain. I've also never tried to lose weight with other people, so I'm hoping this also helps.

OP posts:
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EnglishGirlApproximately · 05/07/2025 12:39

Hello @Rallentandai just posted above as I'm at the same stage as you, so we might be starting together! I'm 51 and despite my best efforts I just can't lose weight. I have exercised, dieted, calorie counted and I'm stuck at the same weight give it take a pound.

Rallentanda · 05/07/2025 12:48

EnglishGirlApproximately · 05/07/2025 12:39

Hello @Rallentandai just posted above as I'm at the same stage as you, so we might be starting together! I'm 51 and despite my best efforts I just can't lose weight. I have exercised, dieted, calorie counted and I'm stuck at the same weight give it take a pound.

It is so bloody depressing not to be able to shift it! I actually do exercise and eat well most of the time, and so at least I'm not progressively getting heavier, but that is no consolation when I have lost a bit and bam, there it is again!
But we will win!! 💪

Elvish · 05/07/2025 12:50

Mounjamtastick · 05/07/2025 10:44

Can I just rant for a moment?

So I will have my first injection on Monday. I decided to tell my mum and MIL I’m starting Mounjaro (we eat with them regularly). Both know I’ve struggled with my weight my whole life.

Mums reaction: ‘that’s cheating you just need to eat less, what about low carb again you did well on that?’ - yes mum, then came off and regained 4 stone in a year. Also how can it be cheating? I wasn’t aware I was in a competition with anyone.

MIL (who also struggles with her weight and has been on slimming world for 18 years gaining and losing the same 3 stone): come to slimming world with me it really works and you never feel hungry. My friend has done weight loss jabs and she’s lost too much she looks awful now.’ - I’ve done slimming world, found it fine but didn’t lose anything significant (PCOS so it’s possibly too carby for me), and what a lovely problem for her friend to have.

I just feel so deflated. Finally someone has come to me with a possible cure for obesity that’s plagued my entire life and I’m told I’m cheating and that I shouldn’t do it. Why is my weight a morality problem to everyone and not a simple medical one??

This is exactly why I'm not telling my mum.

She means well, she loves me and will worry about side effects, I know anything she says is coming from a good place.

But I don't want to hear it just now! I need to get this weight off my body. I'm 48 and have gone through the menopause, I drink too much and don't exercise. Could I do it without the injections? Maybe, but I've been overweight most of my life so clearly it wouldn't be easy!

I'm seeing the injections as healthcare. I have high blood pressure, I'm pre-diabetic, my cholesterol isn't good. I don't think taking medication to be healthy is "cheating", so I'm thinking of monjaro as just the same as amlodipine I take each day to reduce my BP.

Thischarmlessgirl · 05/07/2025 12:52

@JimmyGrimble thank you, I hope you are right though trying to console myself with a loss is a loss
@Mounjamtastick I’m sorry that your family aren’t being supportive, unfortunately there’s lots of judgement and sometimes competitiveness. I haven’t told anyone because I can’t be arsed with other peoples opinions, I also have teenage daughters so conscious of body talk around them. Try and focus on what’s right for you, essentially it’s nobody else’s business
Well done to everyone else taking the plunge and those seeing some pounds shift

AirborneElephant · 05/07/2025 12:59

First full week today. SW 88.9. CW 85.3. So 3.6kg less 🍾

I have not been counting but have been eating much more healthy and cut out snacks and alcohol. Ensuring at least 60g protein a day, plus average 1100 active calories per day.

EnglishGirlApproximately · 05/07/2025 13:24

Rallentanda · 05/07/2025 12:48

It is so bloody depressing not to be able to shift it! I actually do exercise and eat well most of the time, and so at least I'm not progressively getting heavier, but that is no consolation when I have lost a bit and bam, there it is again!
But we will win!! 💪

Same, my diet is ok - not amazing but not terrible and I'm.fairly active which in the past has been enough!

Artymummy10 · 05/07/2025 13:37

I had my first injection on Wednesday and am finding this amazing so far. I normally get shakes throughout the day as my blood sugar is so unstable but I’ve had none at all. It’s so freeing and I realise how much worrying about getting shaky has been affecting my life!

Bunnie22 · 05/07/2025 15:24

Mounjamtastick · 05/07/2025 10:44

Can I just rant for a moment?

So I will have my first injection on Monday. I decided to tell my mum and MIL I’m starting Mounjaro (we eat with them regularly). Both know I’ve struggled with my weight my whole life.

Mums reaction: ‘that’s cheating you just need to eat less, what about low carb again you did well on that?’ - yes mum, then came off and regained 4 stone in a year. Also how can it be cheating? I wasn’t aware I was in a competition with anyone.

MIL (who also struggles with her weight and has been on slimming world for 18 years gaining and losing the same 3 stone): come to slimming world with me it really works and you never feel hungry. My friend has done weight loss jabs and she’s lost too much she looks awful now.’ - I’ve done slimming world, found it fine but didn’t lose anything significant (PCOS so it’s possibly too carby for me), and what a lovely problem for her friend to have.

I just feel so deflated. Finally someone has come to me with a possible cure for obesity that’s plagued my entire life and I’m told I’m cheating and that I shouldn’t do it. Why is my weight a morality problem to everyone and not a simple medical one??

This is why I havnt told anyone ......except you guys

heroofalexandria · 05/07/2025 15:30

Just done my first dose. Very nervous of side effects but decided I needed to go for it. As pp said ‘I just need to get this weight off my body’

1023nina · 05/07/2025 15:35

just done my first 💉, will be keeping a close eye on sugar levels closely via my sensor reading and apps.

good luck everyone x

AbitSceptical · 05/07/2025 16:05

Mounjamtastick · 05/07/2025 10:44

Can I just rant for a moment?

So I will have my first injection on Monday. I decided to tell my mum and MIL I’m starting Mounjaro (we eat with them regularly). Both know I’ve struggled with my weight my whole life.

Mums reaction: ‘that’s cheating you just need to eat less, what about low carb again you did well on that?’ - yes mum, then came off and regained 4 stone in a year. Also how can it be cheating? I wasn’t aware I was in a competition with anyone.

MIL (who also struggles with her weight and has been on slimming world for 18 years gaining and losing the same 3 stone): come to slimming world with me it really works and you never feel hungry. My friend has done weight loss jabs and she’s lost too much she looks awful now.’ - I’ve done slimming world, found it fine but didn’t lose anything significant (PCOS so it’s possibly too carby for me), and what a lovely problem for her friend to have.

I just feel so deflated. Finally someone has come to me with a possible cure for obesity that’s plagued my entire life and I’m told I’m cheating and that I shouldn’t do it. Why is my weight a morality problem to everyone and not a simple medical one??

My planned response to the ‘it’s cheating’ complaint is to ask, “is it cheating if a person
Takes paracetamol for a headache
bottle feeds a baby when they could breast feed
takes blood pressure medication when they still drink alcohol
flies to Spain when they could walk
sends an email rather than writing a letter and sending it in a horsedrawn stagecoach”

Of course someone might say yes all these things are also cheating, but that person is probably a sanctimonious twat.

Humans develop technologies and use them. That’s it.

Wiggles33 · 05/07/2025 17:08

So I’m due my second dose tomorrow and I have definitely felt it wearing off as the week has gone on! Has great suppression and just general non-interest in food earlier in the week but today have fallen back into old habits of picking at something everytime I go past the kitchen etc. Has opened my eyes to how important it will be to kick those habits once I come off of it. Did anyone else notice a decline toward the end of their week? Hoping my picky bits haven’t ruined any weight loss result tomorrow.

ByLemonFish · 05/07/2025 17:18

Yes, I was due to take my 2nd dose tomorrow, started noticing a difference yesterday, feeling peckish all day. Had 2 squares of dark chocolate
Anyway I took 2nd dose this morning, so Thursday and Friday will be my "hungry days" instead of the weekend, if that makes sense

VordLoldemort · 05/07/2025 17:33

Im due my second dose on Monday, have noticed the food noise coming back a bit last night, I managed to satisfy that with a bowl of strawberries, light squirty cream and 2 crushed mini meringues which left me feeling very full. I’d normally reach for the snacks, so it is working as is intended and I have to remember that hunger is normal and I struggled to get many calories in the first 3 days so my body definitely needed it.

have also downloaded the Shotsy app to track progress!

Em85kk · 05/07/2025 18:01

Mounjamtastick · 05/07/2025 10:44

Can I just rant for a moment?

So I will have my first injection on Monday. I decided to tell my mum and MIL I’m starting Mounjaro (we eat with them regularly). Both know I’ve struggled with my weight my whole life.

Mums reaction: ‘that’s cheating you just need to eat less, what about low carb again you did well on that?’ - yes mum, then came off and regained 4 stone in a year. Also how can it be cheating? I wasn’t aware I was in a competition with anyone.

MIL (who also struggles with her weight and has been on slimming world for 18 years gaining and losing the same 3 stone): come to slimming world with me it really works and you never feel hungry. My friend has done weight loss jabs and she’s lost too much she looks awful now.’ - I’ve done slimming world, found it fine but didn’t lose anything significant (PCOS so it’s possibly too carby for me), and what a lovely problem for her friend to have.

I just feel so deflated. Finally someone has come to me with a possible cure for obesity that’s plagued my entire life and I’m told I’m cheating and that I shouldn’t do it. Why is my weight a morality problem to everyone and not a simple medical one??

And this is why I won’t tell my Mum! She doesn’t believe in taking lots of medication, for anything, let alone this. I genuinely think she’d be horrified. But I’ve made up my mind and I’m doing it, I don’t need that judgement or negativity.

Hobbiestwriter · 05/07/2025 18:54

I'm day 3 (jabbed Thursday) and it's been different to how I thought it would be.
a bit of nausea on the first day 2 hours in, and less interested in food. But i still want food, wnjy my meals and have had some chocolate (due my period this week), I've not been completely turned off food like some people say.

i just find it easier to talk myself out if snacking or bingeing, I think 'I don't want to do that as I won't loose weight' and then I just choose not to, whereas before I wouldn't be able to stop myself. But if I chose to I could still eat loads, if that makes sense.

I'm 5'9 though so maybe need a bigger dose to get the effects rather than 2.5mg

KeyboardplayerXXX · 05/07/2025 20:04

@hobbiestwriterthat’s exactly my experience! Im on day 2, first jabbed on Friday am

Wiggles33 · 05/07/2025 20:06

Hobbiestwriter · 05/07/2025 18:54

I'm day 3 (jabbed Thursday) and it's been different to how I thought it would be.
a bit of nausea on the first day 2 hours in, and less interested in food. But i still want food, wnjy my meals and have had some chocolate (due my period this week), I've not been completely turned off food like some people say.

i just find it easier to talk myself out if snacking or bingeing, I think 'I don't want to do that as I won't loose weight' and then I just choose not to, whereas before I wouldn't be able to stop myself. But if I chose to I could still eat loads, if that makes sense.

I'm 5'9 though so maybe need a bigger dose to get the effects rather than 2.5mg

Exactly the same my experience! The thoughts still run through my mind but I can avoid the actual act, whereas before I just couldn’t talk myself out of it. However, on W1 D6 now, due my second dose tomorrow, and those effects have definitely worn off and snacking has been much more difficult to manage today. Interesting!

KeyboardplayerXXX · 05/07/2025 20:14

I also have 0 interest in alcohol and would enjoy a glass or two over the weekend previously!

BriceNobeslovesMurielHeslop · 05/07/2025 20:20

Can I hop on this thread too? I had my first injection on Monday, felt pretty queasy until Thursday-ish, and a bit more peckish Friday and today. However I’m definitely more motivated (£130 a month will do that) and less inclined to snack. I’ve been trying to get in about 70gr of protein a day and stop eating by 6pm. I weighed myself for my photos and don’t think I’ll weigh myself again until the end of the 4 weeks- I can get a bit obsessed with it when I’m trying to lose weight.

MeridaBrave · 05/07/2025 20:45

Hobbiestwriter · 05/07/2025 18:54

I'm day 3 (jabbed Thursday) and it's been different to how I thought it would be.
a bit of nausea on the first day 2 hours in, and less interested in food. But i still want food, wnjy my meals and have had some chocolate (due my period this week), I've not been completely turned off food like some people say.

i just find it easier to talk myself out if snacking or bingeing, I think 'I don't want to do that as I won't loose weight' and then I just choose not to, whereas before I wouldn't be able to stop myself. But if I chose to I could still eat loads, if that makes sense.

I'm 5'9 though so maybe need a bigger dose to get the effects rather than 2.5mg

i’m having a similar experience. I’ve got my parents staying and we are sitting down for each meal. I’ve found I’m not particularly hungry - and last night I found it easy not to eat any bread / dessert but I skipped breakfast as wasn’t hungry and wasn’t eating that one with others. But I still ate lunch and dinner (don’t want anyone to know - other than DH). I could eat but feeling fuller quicker and not tempted to snack.

Tomorrow will be more of a test as my parents are leaving and I won’t be sitting down witn family (my DC are older teens, so own thing on Sundays).

MeridaBrave · 05/07/2025 20:52

Mounjamtastick · 05/07/2025 10:44

Can I just rant for a moment?

So I will have my first injection on Monday. I decided to tell my mum and MIL I’m starting Mounjaro (we eat with them regularly). Both know I’ve struggled with my weight my whole life.

Mums reaction: ‘that’s cheating you just need to eat less, what about low carb again you did well on that?’ - yes mum, then came off and regained 4 stone in a year. Also how can it be cheating? I wasn’t aware I was in a competition with anyone.

MIL (who also struggles with her weight and has been on slimming world for 18 years gaining and losing the same 3 stone): come to slimming world with me it really works and you never feel hungry. My friend has done weight loss jabs and she’s lost too much she looks awful now.’ - I’ve done slimming world, found it fine but didn’t lose anything significant (PCOS so it’s possibly too carby for me), and what a lovely problem for her friend to have.

I just feel so deflated. Finally someone has come to me with a possible cure for obesity that’s plagued my entire life and I’m told I’m cheating and that I shouldn’t do it. Why is my weight a morality problem to everyone and not a simple medical one??

So as someone who’s basically been dieting on and off my whole life I see there is an element of “cheating” as losing weight this way doesn’t require nearly as much focus or willpower. So yes it’s easier. But so what? Why does it matter how you get there. it’s not a competition. I mean loads of people take statins to reduce cholesterol and that can be done via careful food choices. Is that cheating also? Or people use dishwashers instead of washing up. There are sometimes just more effficient ways of doing things.

But I would never tell my sisters / mother / MIL / DC (aged 22,19 and 15). As would all be too judgy.

BriceNobeslovesMurielHeslop · 05/07/2025 21:31

I honestly couldn’t care less who knows and who judges me. Apparently 1.5 million people are using it in the UK, including about 8 of my colleagues (nurses). I’ve struggled with my weight since I was a child, my mother has always struggled with her weight, my granny did too and died of a heart attack at 69 after struggling with T2 diabetes. As far as I’m concerned it’s a medication that’s helping me control my blood glucose and a side effect of that is that I don’t think about food all the time.

crazycadetmum · 05/07/2025 21:36

Im nearing the end of my first week..I find myself about to snack at the times I usually would..like when I come home from work.. not because I feel hungry but I think because it's habit..im trying and succeeding to distract myself and keep to 3 meals a?day. Injection has helped..

Mariecat1970 · 05/07/2025 21:43

I did my first jab last night so today was my 1st (full) day- so far feeling great.

Didn’t fancy breakfast, then had egg mayo sandwiches for lunch and made myself eat a very small portion of carbonara for dinner, but I could easily have not eaten anything more after lunch as I felt full.

I know this is early days, but I’m over the moon. This is possibly the first day in my adult life that I haven’t eaten any snacks!

I have a lot to lose, in fact I cried when I actually weighed myself for the consultation as couldn’t believe what the scales said. But taking it one day a time and feeling positive.

SW 17st 6lb
GW 10st 6lb

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