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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2025 Starters thread 4

963 replies

TheSpoonyNavyReader · 20/04/2025 19:22

New thread for all of us.

Thank you for allowing me to rant, share our ups and downs. Our group blows my mind of how we are so supportive of each other.

OP posts:
Thread gallery
25
Letsgetitdone · 06/05/2025 07:32

Good Morning, I love reading about all of the individual journeys going on.
Does anyone top up their dose around day 5?

I weigh daily and on day 4 I was showing as 2lb loss, days 5 and 6 I have been struggling with feeling hungry and having food noise and know I've eaten more than the rest of the week, although still much less than I use to.
Weighed today and it's my 2nd week of only losing 0.5lb, annoyingly I have already got another 2.5 pen in the fridge to use so I'm thinking of taking a 1mg top up on day 5 to help with the suppression and food noise.

GiveMeWordGames · 06/05/2025 08:06

@TryingMJ sorry it's hitting you hard this week. I resorted to Immodium when I was a bit like that two weeks ago.

Having thought I was all at peace on 5mg I woke up this morning and threw up. It may be the early start, as I'm working today, I don't know, but it's not ideal. I've managed some tea and water. This is the one side effect I was hoping I would dodge.😫

GameOfJones · 06/05/2025 08:16

@TryingMJ and @GiveMeWordGames I really hope you feel better soon. That sounds rough! 💐

Bipaloss · 06/05/2025 08:31

Letsgetitdone · 06/05/2025 07:32

Good Morning, I love reading about all of the individual journeys going on.
Does anyone top up their dose around day 5?

I weigh daily and on day 4 I was showing as 2lb loss, days 5 and 6 I have been struggling with feeling hungry and having food noise and know I've eaten more than the rest of the week, although still much less than I use to.
Weighed today and it's my 2nd week of only losing 0.5lb, annoyingly I have already got another 2.5 pen in the fridge to use so I'm thinking of taking a 1mg top up on day 5 to help with the suppression and food noise.

I think a few people do every 4-5 days on here as MJ looses 50% of its effect after 4 days especially on the lower doses where there is less MJ in your body. Some also split doses due to SE. Also read that originally it was advise to take jab every 5 days but they set it at 7 so people wouldn’t forget their dose

im doing my next jab after 6 days as I delayed it one day 2 weeks ago but the effect is starting to loose it affect now end of the week and also want to go back to Sunday jabbing.

Fatmumslim01 · 06/05/2025 08:44

Bipaloss · 06/05/2025 08:31

I think a few people do every 4-5 days on here as MJ looses 50% of its effect after 4 days especially on the lower doses where there is less MJ in your body. Some also split doses due to SE. Also read that originally it was advise to take jab every 5 days but they set it at 7 so people wouldn’t forget their dose

im doing my next jab after 6 days as I delayed it one day 2 weeks ago but the effect is starting to loose it affect now end of the week and also want to go back to Sunday jabbing.

@Bipaloss possibly a silly question but surely if you are doing every 5 days the pen will run out quicker so you have to buy more frequently?

I'm 48 hours post my second 3.75 jab. I usually jab on a Fri but moved it to sun this week due to being away for the weekend. Pleased to report no nausea at all on the second dose compared to the awful nausea last week. So that's a big relief I was worried I'd have to go down to 2.5 and I really didn't want to do that as I was really finding it had worn off my days 5 and 6.

I need to decide whether to stick with a Sunday dose or go back to Fridays. O started Fridays so had the weekend to get side effects out of the way but now I'm thinking maybe Sunday as in new week new jab 😂

Might go up to 5 or may stick at 3.75. I want to.go up as slow as possible as I'm very aware this is a long term thing and I don't want to rush to 15 then have no where to increase it to!

EchoNova · 06/05/2025 08:53

Morning all.

Starting 7.5mg today thank god (I've done 1 month at 2.5mg and 1 month at 5mg)- I felt the last week on 5mg a struggle, I felt no supression & food noise was back so a lot of will power was used. SE's on 5mg were fine, a little bit of nausea after jab day and tired but I was fine after 2 days.

Anyone else moved up to 7.5mg? How did you find it.

Also when did people notice you had lost weight? I'm down 20lbs and the only person that has said anything to me is my beautician and that was because I was getting a bikini wax 😂

Yellowsubmarine55 · 06/05/2025 09:11

Just finished week six with a 3lb loss so that's 17 in total which I'm chuffed about. All on 2.5 🙂

Sorry to read others are suffering, for once all my horrible effects have completely gone and I'm feeling fantastic. Hence why I'm staying on 2.5 for the foreseeable.

Injection 7 this morning.

Bipaloss · 06/05/2025 09:25

Fatmumslim01 · 06/05/2025 08:44

@Bipaloss possibly a silly question but surely if you are doing every 5 days the pen will run out quicker so you have to buy more frequently?

I'm 48 hours post my second 3.75 jab. I usually jab on a Fri but moved it to sun this week due to being away for the weekend. Pleased to report no nausea at all on the second dose compared to the awful nausea last week. So that's a big relief I was worried I'd have to go down to 2.5 and I really didn't want to do that as I was really finding it had worn off my days 5 and 6.

I need to decide whether to stick with a Sunday dose or go back to Fridays. O started Fridays so had the weekend to get side effects out of the way but now I'm thinking maybe Sunday as in new week new jab 😂

Might go up to 5 or may stick at 3.75. I want to.go up as slow as possible as I'm very aware this is a long term thing and I don't want to rush to 15 then have no where to increase it to!

Yes it would run out quicker I’m on 5mg but now on a 7.5 pen using less clicks and planing 5 doses from the pen this time (2x5mg, 2x 6.25 mg ,1x 7.5 mg) but obviously if you dose every 5 days on the full pen dose the pen would run out in 20 days instead of 28 days (if you don’t do golden dose)

I’ve lost around 19lb and people have started noticing since last week that I look slimmer but I think it will be more noticeable when I lost 30lb which half way from my goal weight

Amjam2025 · 06/05/2025 11:27

Morning Everyone!
Week 8 day 6 (4th 5mg jab last Weds pm)
SW =10 stone 10lb
CW = 9 stone 7lb
17lb loss so far in almost 9 weeks
TW = 9 stone 4lb and then go from there

So 1lb loss again this week, slow progress the last few weeks but that's good in the long run i spose.

Had sulphur burps and horrendous stomach pain and water diarrhoea yesterday which I've never had before on MJ. Not sure if its because I had a Chinese takeaway on Saturday night ( not had a chinese takeaway since the very start of mj) or if its just general late onset side effects.

Bought a 7.5mg pen which I'm due to start on Thursday (my new jab day ready for my hols) but really unsure whether to count clicks and do another 5mg or move up, suppression can very massive from day to day at the mo. Was ready to move up till this happened :(

Lolliz87 · 06/05/2025 11:37

Amjam2025 · 06/05/2025 11:27

Morning Everyone!
Week 8 day 6 (4th 5mg jab last Weds pm)
SW =10 stone 10lb
CW = 9 stone 7lb
17lb loss so far in almost 9 weeks
TW = 9 stone 4lb and then go from there

So 1lb loss again this week, slow progress the last few weeks but that's good in the long run i spose.

Had sulphur burps and horrendous stomach pain and water diarrhoea yesterday which I've never had before on MJ. Not sure if its because I had a Chinese takeaway on Saturday night ( not had a chinese takeaway since the very start of mj) or if its just general late onset side effects.

Bought a 7.5mg pen which I'm due to start on Thursday (my new jab day ready for my hols) but really unsure whether to count clicks and do another 5mg or move up, suppression can very massive from day to day at the mo. Was ready to move up till this happened :(

My stomach did not react well to a Chinese takeaway couple of weeks ago. I was being sick and had diarrhoea! Think it’s the fact that it’s fried a lot of it (or was with me anyway). So fingers crossed you’ll be ok x

Amjam2025 · 06/05/2025 11:50

@Lolliz87 thanks for replying, yes i ate chicken fried rice, chicken chow mein plus chips so hopefully thats the explanation! I'm in work today and (touch wood) so far so good.....My stomach just feels a bit tender.
Sorry you were sick too, its not pleasant at all is it!
Will definitely be avoiding Chinese food for a long while, which is a shame cos it's my favourite!

Lolliz87 · 06/05/2025 12:07

Amjam2025 · 06/05/2025 11:50

@Lolliz87 thanks for replying, yes i ate chicken fried rice, chicken chow mein plus chips so hopefully thats the explanation! I'm in work today and (touch wood) so far so good.....My stomach just feels a bit tender.
Sorry you were sick too, its not pleasant at all is it!
Will definitely be avoiding Chinese food for a long while, which is a shame cos it's my favourite!

Me too but I just think of having to be sick in the bath (I was so ill) and it puts me off the craving 😂😂😂. Chinese will just have to wait until we are at target and off the MJ lol

TheBossOfMe · 06/05/2025 12:48

I jabbed this morning, two days early this week because I've got a flight on my usual jab day (Thu) and I don't want to take my pen with me. First 7.5ml dose, and I feel absolutely disgustingly nauseous already, first time I've had this. And feeling bloated after a run this morning. I was very nearly sick just now, just about managed to hold it back, but definitely feeling the step up in dose. Bleurgh.

EchoNova · 06/05/2025 13:37

TheBossOfMe · 06/05/2025 12:48

I jabbed this morning, two days early this week because I've got a flight on my usual jab day (Thu) and I don't want to take my pen with me. First 7.5ml dose, and I feel absolutely disgustingly nauseous already, first time I've had this. And feeling bloated after a run this morning. I was very nearly sick just now, just about managed to hold it back, but definitely feeling the step up in dose. Bleurgh.

I'm exactly the same. Took my first 7.5mg jab about 9am this morning and I'm very nauseaus and have an awful headache. I'm Just drinking water and I've managed to get an aldi protein pudding into me. But can't stomach anything else. I've been very lucky to not have many SE's on previous doses ( a little bit of nausea on week one of 5mg but not as bad as I am today).

Fatmumslim01 · 06/05/2025 14:41

TheBossOfMe · 06/05/2025 12:48

I jabbed this morning, two days early this week because I've got a flight on my usual jab day (Thu) and I don't want to take my pen with me. First 7.5ml dose, and I feel absolutely disgustingly nauseous already, first time I've had this. And feeling bloated after a run this morning. I was very nearly sick just now, just about managed to hold it back, but definitely feeling the step up in dose. Bleurgh.

@TheBossOfMe that's brave of you going up a dose 2 days before a flight id be too nervous!

Hope you and @EchoNova feel better soon!

Aboutmeabouttime · 06/05/2025 14:52

Anyone else considered that jabs might be affecting them differently against their menstrual cycle? Just done jab after end of my period, no change in strength but I also feel really nauseous today… tried to eat lunch but only managed a bit of it. Not felt suppression/SE effects like this for a while but I remember after my period last month I had a good loss/felt differently.

Solidarity to all those feeling rough today… sipping water, trying to concentrate in the office 😫

TheBossOfMe · 06/05/2025 14:53

@Fatmumslim01 Brave, or incredibly dumb? I've realised it was a really stupid thing to do - gone up a dose before a flight, and increased dose when I had a shorter window from the last jab, so probably still had an amount of MJ still in my system. Idiot me - I should have counted clicks and done a smaller dose. Feeling extremely sorry for myself - hideous nausea and freezing cold. I've managed to eat some lunch, and am mainlining peppermint tea but it's a busy day at work, so I really didn't need to feel like this!

I have some super fancy peppermint teabags though - the Teapigs ones. I wouldn't normally splurge on fancy tea, but I had a voucher, which made them not quite so spendy. They make a very lovely cup of mint tea.

TheBossOfMe · 06/05/2025 15:03

@Aboutmeabouttime - ooh, that would be something interesting to track. Although I just finished an 18 day period so my cycle is all over the place!

TheSpoonyNavyReader · 06/05/2025 15:46

SA are very real on 7.5ml I have no idea how anyone goes up to 15ml. I am not sure if I will go up to 10ml

I have never been so cold, my nipples now have their own postcode.

OP posts:
Flamethrowers · 06/05/2025 15:48

Anyone else finding they are getting exhausted? I did a thirty minute personal training session and had to do a half hour sleep afterwards.

Bipaloss · 06/05/2025 15:52

TheSpoonyNavyReader · 06/05/2025 15:46

SA are very real on 7.5ml I have no idea how anyone goes up to 15ml. I am not sure if I will go up to 10ml

I have never been so cold, my nipples now have their own postcode.

This is why I’m trying to hold on 5mg as long as I can , did my 5th 5mg yesterday and since start of last week I’m so cold (used to be a couple of days in the morning only) , today is much worse then it has been to the point I had to up heater to 25 degrees and have a blanket on my lap (wfh today)

im not feeling 5mg is a strong now though so il probably do another week and then Up to 6.25

Flamethrowers · 06/05/2025 16:02

Apparently your advised to use additional birth control while on WLI if you take the pill (when you start/change dose) as the gastric side effects can also affect pill absorption.

Amjam2025 · 06/05/2025 16:08

Bipaloss · 06/05/2025 15:52

This is why I’m trying to hold on 5mg as long as I can , did my 5th 5mg yesterday and since start of last week I’m so cold (used to be a couple of days in the morning only) , today is much worse then it has been to the point I had to up heater to 25 degrees and have a blanket on my lap (wfh today)

im not feeling 5mg is a strong now though so il probably do another week and then Up to 6.25

@Bipaloss I think I'm going to do a 6.25mg dose with my new pen on Thursday and perhaps work my way up to 7.5mg.
This might be a really silly question but if I gave myself 4 x 6.25mg doses or even a couple of 6.5mg doses does that mean that there will be even more "golden dose" left at the end which i will need to do the hard twist on or extract out with a syringe?
I've not counted clicks before, I've always used the full dose then chucked the pen away at the end of the 4 doses.

Bipaloss · 06/05/2025 16:12

Amjam2025 · 06/05/2025 16:08

@Bipaloss I think I'm going to do a 6.25mg dose with my new pen on Thursday and perhaps work my way up to 7.5mg.
This might be a really silly question but if I gave myself 4 x 6.25mg doses or even a couple of 6.5mg doses does that mean that there will be even more "golden dose" left at the end which i will need to do the hard twist on or extract out with a syringe?
I've not counted clicks before, I've always used the full dose then chucked the pen away at the end of the 4 doses.

I’m counting clicks for the first time too but not been doing golden doses

on 7.5 mg pen
40 clicks = 5mg
50 clicks = 6.25 mg
60 clicks = full dose / 7.5 mg

in one pen there is 240 clicks (without golden dose) so calculate based on that

I’m planing 2x40 ,2x50, 1x 60 =240 so 5 jabs instead of 4x60 (without golden doses)

needtolose70lb · 06/05/2025 16:15

Checking back in and trying to catch up on all the messages.

SW: 17st4lb
CW: 14st10.8
GW: 12st4 (but would really like to see the 11s)

Currently means i have lost 34/5lb i think. Hooo boy!

Week 9, took 10th jab last Thursday.

Unlike a lot of people on here I have stuck to the original prescriber pattern despite any misgivings and so am now halfway through 7.5mg. I have not had any nasty side effects so it seems to be ok for me to do it this way. There is a niggle about going up fast and having nowhere to go but my prescription is up to 10mg next and then sticking on that for 4 pens before a review. I decided to go with the plan and trust the process rather than mess with it and not know if any problems came from my messing. It is kind of how my brain works!

I still get cold. I still get tired at night, more so on day 2 or 3. I still have mild constipation so go every 2-3 days instead of every day. But that's it. I get hungry at mealtimes but happy to wait to eat until then. I eat a good portion of food and make good food choices and can actually stop when I am full. A first.

The best news is that I still don't crave alcohol or bags of peanut m&ms or two bagels for breakfast or any of the other sugar-based stuff I couldn't do without before.

I did see 14st9.9lb yesterday which would be the lowest I have been for at least 5 years but it bounced up this morning. Not surprised because we ate out twice this weekend and i made good choices but still went a little over calories and had saltier/carb heavy meals. So i know it will go again in the next couple of days.

That;s abother one of the best things. I am not giving up or feeling disheartened on the days i maintain or bounce up and down within a couple of pounds .I would like it always to go down but this is my pattern and i genuinely believe i can keep going and i have never ever ever ever felt like that before.

Next mini goal - go below that 14st 10 for a few days in a row.
Then below 200lb (so 6lb+ off)
Then below 14.

I am visiting family in germany during half term and if i could be anywhere close to the 13/14 border then i will be extremely happy. They are rake thin.

Well done all!