April 2025 Starts - Thread 2

[QS90]

Following on from thread 1 - !

I drew it up and injected with the same needle no problem @StrikeForever

I have a dilemma.

Injected bonus dose today. Rejected by ZAVA on Wednesday due to bmi under 30 (originally was over when I got first pen). I then ordered via pharmacy2u but still no response, just showing as consultation received.

Do I hold out or order from original provider tomorrow so I get in time for next Friday?

What if I end up with 2?

I think suppression is really starting to kick in for me now 🥳 All I’ve eaten today is a protein smoothie for lunch (was higher calorie as had banana and peanut butter in), it’s now a couple of hours past my dinner time and I’m still not hungry in the slightest. I also went shopping this evening and I did buy some unhealthy stuff (biscuits and some ice cream) but I felt no temptation whatsoever from any of the treats I would normally buy/want to buy, and only got the things I did buy for dp and the kids. It’s just so freeing ❤️

I would say you have roughly 260 clicks until the mechanism locks. So that allows you to inject 4x 60 clicks (2.5mg) plus few spare for priming . However when you have done that and you look in the barrel there is still a lot of drug left. People have said, using separate needles/ syringes they can extract a further 0.9 mil which equates to a 3.75mg dose

Thank you @SurreyGirl69 . So it's the number of clicks the pen allows!

Yes! I did it today. It was totally fine. I even had to pierce the membrane twice because I didn’t draw up quite enough the first time. It was not as pain free as the pen but it was a tiny sting - no problem at all. I’ve got ten of the syringes and I’m quite happy using them going forward.

Well, I did it!!

I can’t take the full credit because I just mentally couldn't make myself do it so asked my sister - who’s a midwife - to do it for me 😆 I did jump a little but it was really ok. I think I’ll be ok doing the second jab myself.

Now, I can be one of those people who say confidently “It really doesn’t hurt!’

I do find suppression has weakened - I’m now week 4, day 3. I do keep my own in the fridge

Well, my small bout of constipation has resolved itself… took my 4th dose of 2.5 this evening and about 2 hours later was sat on the loo with diarrhoea (sorry TMI)! First time I’ve experienced that side effect so not sure what that’s about. Now drinking loads of water to compensate!

WK4 D1

Took my 4th dose this morning & weighed.

Wk1. -10 lbs
Wk2 -4 lbs
Wk3 -2 lbs

SW 15 st 10lbs
CW 14 st 8 lbs
GW 12 st

Very happy and will be more than happy with a small loss each week going forward as was worried about muscle loss & hair loss!

I am still getting good suppression & no food noise. I have however been able to eat a bit more in the evenings this week. A smaller portion of our usual family meal.
All good healthy food still!

Id be really happy with this level of suppression going forward. Planning to do my 5th dose next week. Have some Luer lock syringes ready!

Also have my 5mg pen ready and will see how I feel. Hoping to stay on 2.5.

I’m about to take my 3rd dose, I’ve moved it from Saturday to try and ensure the worst of the side effects have passed by Monday even though I’d rather have the suppression during the week.

I’ve lost nothing this week in fact a 1/2 lb gain but I did lose nearly a stone in the first week after the horrific diarrhoea so I wasn’t expecting (or wanting) to keep losing at that rate.

At the moment I feel like I can’t start thinking about calorie / protein tracking as I am just trying to find foods that don’t exacerbate the side effects.

This week has been a lot better than the first one with only a couple of episodes of rushing for the loo but there is still ongoing mild discomfort and I never feel quite like I’ve fully completed a bm.

Maybe ring Pharmacy2U in the morning

It doesn’t twist to load the drug after the 4th

Guys, I’m a bit confused by talk of golden doses and 3.75. So here is my first Mounjaro pen (2.5). I’ve had my 4 doses. Is this now an empty pen or is there a final dose I can take (I can’t tell if there’s liquid inside)? If so, I’ve bought syringes/needles to hopefully extract this. But my question is this, if there’s an extra dose in my pen, can I use it on top of my 2.5mg dosage this week (taken on Thursday night)? It would be good to have the extra suppression until I start on my new 5mg pen, as it’s definitely waning. Thanks!

Oh, and the pen has been kept in the fridge the entire time.

Yes there is still liquid inside - from what I’ve read people seem to get enough from the end of the pen to inject 3.75mg. So if you draw up 0.6 ml that would give you another 2.5 mg dose. Or if you want to top up this weeks dose you could take 0.3 ml which would be 1.25 meaning you had taken 3.75 in total this week. I don’t see why you couldn’t take a full 2.5 mg again which would give you 5 in total for this week but people do seem to get a lot of side effects moving from 2.5 - 5….

hope that makes sense!

So my plan for the 4th week was to try out 3.75mg with the 2.5 pen. So I did my dose like normal and then extracted 0.3ml to give me the extra 1.25mg of the medicine. If you’ve done your 4th medication and you’re now talking about your 5th week on 2.5mg, you need to inject 0.6ml from the liquid remaining

I think the guidance is to have at least 4 days between doses (though possibly less of an issue if you’re only taking a partial dose rather than a full one?). I’ve heard a few times that the golden dose in a 2.5 is more like 3.75.

If it was me (assuming you don’t want to wait a full week for next dose) then I’d take the full remaining amount on Monday (4 days from your last dose) and then start the 5mg pen a week later.

Good morning everyone, I've had a catch up on the thread after two days and its great to hear everyone seems to be getting on well.

Interestingly, the colorectal consultant I saw this week told me in no uncertain terms that water consumption has absolutely no affect on constipation at all, and he should know! He told me it is all about fibre.

I am on W2D2 today and am chuffed to bits that I lost 3KG / 6.5lbs last week with virtually no effort at all, there was one evening where I was getting cravings, but otherwise it has been easier than I thought.

Day 20 for me, so week 3 day 5. One stone gone. I’m delighted and now into the last stone but ideally a stone and a half. My main symptoms are I’m freezing most of the time. And I can’t get heat into me. Funny taste in my mouth but it’s probably lack of carbs. Otherwise I feel fine. Due my fourth dose on Monday and then I’ll order the 5mg but I plan to take the bonus dose and hopefully it’s 3.75 to ease me into 5mg. I’m still doing OMAD and fast to dinner apart from tea and coffee and 3-4 litres of water. My meal has no carbs apart from veg. OMAD works for me and always has but I used to find it a struggle and overeat on my meal. I don’t know. Delighted with the results so far. I know the rest will come off slower but I will continue with what I’m doing and hopefully it won’t be too slow.
Happy Saturday x

I'm on week 4 and I'm starving, I feel like I'm getting no suppression so will be holding out on willpower until I do my bonus dose on Wednesday I didn't keep my first pen in the fridge but I will definitely be keeping my 5mg in the fridge to see if that makes any difference!

About to take my 4th dose. I haven’t lost anything this week. Stupidly I didn’t weigh until 2.5 weeks in and I lost 3lbs. I feel like I lost some the first couple of weeks but this week is a big fat disappointment as I have been careful with my intake. I lost a few stone on the fast 800 5 years ago and literally dropped a lb every few days for 3 months. Peri now though and heavier than ever and it is so so slow.

W3 D1

starting weight - 12st 9
current weight 12st

loss in W1 - 6lb
loss in W2 - 3 lb
GW - 10.4-10.7 or so

Almost no side effects, occasional minor constipation /indigestion only.

Am calorie counting to aim for min 1000 Cals per day. Very strong suppression for first 4 days post jab, does wane a little but manageable.

Very pleased with how things are going. Good luck to everyone.

Hi everyone. Another loss of 3lbs for me this week which I’m very happy about.

For some reason I had massive cravings yesterday and had to have ice cream and chocolate. I’m pretty sure it’s hormonal - felt very hungry too. But who cares - it’s all part of the journey, right? Treats are what make life… life.

I have injected my first 5mg dose this week. I’ve felt a bit burpy and heartburne-y but that’s about it.

We talked about bonus doses earlier. In my 2.5mg pen there was a bonus dose of 0.7ml left, so just over another dose of 2.5mg. I withdrew it from the pen and then the rest from the 5mg pen to make it 5mg. Nice and easy.

Weekly losses so far:

1. 4lbs
2. 2lbs
3. 2lbs
4. 3lbs

11lbs off in a month. :) BMI has gone from 31.8 to 30.2. So close to being overweight, woo! 😂

Week 3 Day 2. Weighed again this morning. Currently 11lbs down. Think I’m gonna stick to lbs as keep confusing myself.

so
SW around 260lbs
CW 249lbs
First TW 220lbs
Final TW 165lbs.

I have ordered my 5mg pen. One 2.5mg dose left to take on Thursday, then I plan to take the golden dose the week after.

I think I slightly stalled this week as I really wasn’t eating enough to fuel my body as I wasn’t feeling particularly hungry for most of the week. Tried to up my intake to more regular intervals. Which eventually shifted another 2lbs.
Still virtually impossible to drink enough fluid when I’m at work, but actively upping that at home.