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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

April 2025 Starts - Thread 2

1000 replies

QS90 · 11/04/2025 23:32

Following on from thread 1 - !

OP posts:
Thread gallery
21
Mels2025 · 24/04/2025 22:03

wlinewbie0425 · 24/04/2025 07:06

@BonnieClydeSW15day 1 for me too (well I injected at 10pm last night) following this thread for all the great tips but with most people being so much further on we also now have a late april/early May starts thread if you are interested.

New thread sounds good, what's it called? I can't find it!.....oops, I obviously can't type, found it now! Thanks 👍

BadSpellaSpellaSpella · 24/04/2025 22:06

Pepperwaggytail · 24/04/2025 19:05

A really big bonus is that I’m finding exercise lots easier! I’m even more flexible in Pilates. Plus actually looking a bit better in gym clothes is boosting my confidence! What’s not to love!
My only real fear now is that when I’ve lost the weight and achieved a BMI of around 22-23? I’ll then put a bit of weight on and won’t be heavy enough to get Mounjaro again! Imagine needing to reach a BMI of 30 before you can get it again, instead of being able to nip any weight gain in the bud, it almost encourages you to yo yo. Or to stockpile a few pens? I really don’t want to take a maintenance dose long term, can’t afford to!

Yes I was wondering this, that would be a nightmare

Galadali · 24/04/2025 22:27

WinterOnItsWayOut · 24/04/2025 21:58

@Galadalimy first jab kickstarted a period for me (52 and in early peri with patchy but heavy periods). It lasted 19 days in full flow and just finished. Now just had confirmed I’m anaemic so off to the Docs tomorrow for serious iron…

Am hoping it’s a one off reaction as has been horrendous!

There's still a lot that's unknown about this drug, that's for sure. I hope things settle down for you x

Incognitoburrito88 · 24/04/2025 22:39

TC4 · 24/04/2025 17:23

So who are the Friday injection people? And is anyone moving up to 5mg tomorrow?? I am planning to 🙌🏻🙌🏻

Hey - I’m a Friday injecter! Tomorrow is week 4 for me. I’m stressing about ordering my next pen. Can’t decide whether to stick with 2.5 or go up to 5. I had lost 9lb when I weighed on Monday but now that’s down to 8lb and I felt hungry this evening and had a beer after a stressful day.

SusanSometimes · 24/04/2025 22:59

Raffles134 · 24/04/2025 19:41

🙋‍♀️ I’m a Friday jabber! 😆
Taking my 4th tomorrow. Will try and get my 5th dose out of this pen, then decide the week after whether to move up to 3.75 or stay on 2.5.

Exactly the same here, jabbing my 4th dose tomorrow evening. I'm getting great suppression on 2.5 with no side effects, so if I've lost weight I might stay on that dose.

The only thing is, I'm on holiday atm and would normally weigh in Saturday morning. I'll have to wait 24 hours until Sunday when I'm home. I know it's not long, I'm just desperate to know what I've lost this week.

TC4 · 24/04/2025 23:10

SunnySpellsAhead · 24/04/2025 21:58

Thanks, it's all a learning curve 🙂

It will be for most people - just use whatever syringe you have and draw out the liquid from the red port pull
it back further than you need to so there’s a gap and then before injecting hold straight up right flick the syringe gently a few times to get any bubbles to go to the top and then push the liquid up so there is no longer a gap and the needle is full of liquid - once you have done it a couple of times it will seem so straight forward

QS90 · 24/04/2025 23:29

SunnyPop · 24/04/2025 18:49

Has anyone found their suppression hasn't been as effective as the weeks go on? I had my 4th injection of 2.5mg yesterday and I am STARVING today. The first week or two of being on MJ I could barely finish a meal but that is not the case now 😬 I lost 2lb this week, making it a total of 14lb loss so far so I'm pleased with that, but I'm worried about giving in and binging on the chocolate and ruining it all 🍫

My Auntie has been on it a few months. Was chatting to her about it on week 2ish, and said I was thinking about staying on 2.5mg, because my appetite suppression was so good. She told me that the suppression would likely be less, by the fourth dose, and I might find I needed to go up (that is, my body would become accustomed to it).

The other thing I've wondered about, is whether the medication gets weaker, as the month progresses, because most people don't keep the pen in the fridge. I might start keeping mine in the fridge all the time, to see whether it makes a difference. No point paying more for stronger doses, if this is the case.

OP posts:
QS90 · 24/04/2025 23:33

MJafterWLS · 24/04/2025 18:49

Due to take my 4th jab tomorrow. I took it a day early last week (so a week ago) and I am definitely feeling the hunger and food noise return this afternoon as it’s wearing off.. hope I can hold out with my good habits until I jab tomorrow! Down 16lb now in just under 3 weeks so super happy with that and my BMI this morning was 29.9! 28lb to go till my GW. Planning on talking the golden dose next week then moving up to 5mg - where is everyone getting their extra needles from?

What an amazing loss - go you!!

I just got my syringes from Amazon. Microfine ones, where the needle is already built in. Even had a comment in the reviews section, from someone who had used it for the golden dose.

OP posts:
QS90 · 24/04/2025 23:42

Pepperwaggytail · 24/04/2025 19:05

A really big bonus is that I’m finding exercise lots easier! I’m even more flexible in Pilates. Plus actually looking a bit better in gym clothes is boosting my confidence! What’s not to love!
My only real fear now is that when I’ve lost the weight and achieved a BMI of around 22-23? I’ll then put a bit of weight on and won’t be heavy enough to get Mounjaro again! Imagine needing to reach a BMI of 30 before you can get it again, instead of being able to nip any weight gain in the bud, it almost encourages you to yo yo. Or to stockpile a few pens? I really don’t want to take a maintenance dose long term, can’t afford to!

The patents for Wegovy and Monjourno, expire 2028 and 2032 respectively, so although it's still a way off, the cheaper versions will come!! If I feel I need a maintenance dose at the end, I keep telling myself that an expensive few years, is still better than an expensive lifetime cost...

That said, I can't imagine being a healthy weight again! I feel that if / when I get there, the process will have been so transformative (both physically and metaphorically), I might not have the urge to binge / eat badly. I don't think I can know yet, how I'll feel then, iyswim? Am also using the time on the jabs, to try and cultivate better coping strategies / a better relationship with food generally, to hopefully reduce the chance of yo-yoing!

OP posts:
CreakyandSneaky · 25/04/2025 00:08

Hi all, just catching up on everyone's progress. I'm W3D2 and just about to order next dose. I've lost 11 lbs so really pleased, but will go fo 5ml as I do feel the suppression is less than it was. Just wondered what the deal is with ordering once your weight gets lower. I'm with Asda at the moment, but my BMI has just dropped under 30 (29.3!) Anyone know whether that's likely to be a problem? Who is good for reordering as weight drops and/or maintenance doses? I have a way to go, but just thinking ahead! As some others have said, I loathe the faff and indignity of doing the photos again each time too. Which providers are best?

SausageRoll90 · 25/04/2025 07:00

Morning all! Another Friday jabber here @TC4 and will be doing mine this evening before I go to bed.

End of Week 2 (2.5mg)
SW: 16st 9.5lb
CW: 16st 4.5lb
W1: -4lb
W2: -1lb
Total loss: -5lb

I'll be honest, I'm a bit disappointed with just 1lb off this week because I've been tracking my calories and done exactly the same this week as i did last week but I know 5lb over 2 weeks is good. I just hope that week 3 brings better results 🤞🏻

Incognitoburrito88 · 25/04/2025 07:01

Morning everyone

Wk 4 D 1

SW 13st 7
CW 12st 13
Total loss 8lb

Morning everyone - I’ve had good suppression but no movement on the scales all week 😢 Did my 4th jab this morning. Currently thinking I will probably go up to 5mg next month. I’ve got syringes to do the bonus dose so I’m set for one more week but need to order my next pen over the weekend so I can collect on Friday…

I’m quite constipated so going to try and have a day of foods which usually get me moving and keep drinking plenty of water. Hopefully I’ll get a whoosh.

SausageRoll90 · 25/04/2025 07:06

Incognitoburrito88 · 25/04/2025 07:01

Morning everyone

Wk 4 D 1

SW 13st 7
CW 12st 13
Total loss 8lb

Morning everyone - I’ve had good suppression but no movement on the scales all week 😢 Did my 4th jab this morning. Currently thinking I will probably go up to 5mg next month. I’ve got syringes to do the bonus dose so I’m set for one more week but need to order my next pen over the weekend so I can collect on Friday…

I’m quite constipated so going to try and have a day of foods which usually get me moving and keep drinking plenty of water. Hopefully I’ll get a whoosh.

Similar here with the constipation. That's my mission this week is to get things moving better in the hope it helps.

I've not previously considered doing anything with the golden dose but part of my is wondering about using some of the golden dose at my 4th injection to boost it to 3.75mg before moving to 5mg in week 5 🤔 because if I still get very little weight movement in week 3 I don't really want to just do another 2.5mg knowing it's not enough for me... I'm not 100% on this idea yet as I had planned just to stick to the recommendations of dosing but I feel frustrated this morning with slow progress this week.

TC4 · 25/04/2025 07:09

SausageRoll90 · 25/04/2025 07:00

Morning all! Another Friday jabber here @TC4 and will be doing mine this evening before I go to bed.

End of Week 2 (2.5mg)
SW: 16st 9.5lb
CW: 16st 4.5lb
W1: -4lb
W2: -1lb
Total loss: -5lb

I'll be honest, I'm a bit disappointed with just 1lb off this week because I've been tracking my calories and done exactly the same this week as i did last week but I know 5lb over 2 weeks is good. I just hope that week 3 brings better results 🤞🏻

Edited

I do mine in the evening as well - let’s hope we both get it done and get a good sleep after it!! I’m worried for side effects as moving up a dose but 🤞🏻🤞🏻 hopefully will be fine- I need to go to London on Sunday to watch the London marathon so I have to be ok lol.

your weight loss is doing absolutely fine and if you have been doing this for 2 weeks and starting a 3rd you are most likely moving through your cycle so that will attribute to slower weight loss, and also the big losses in week 1 are down to water retention and then 1lb in a week is amazing

Incognitoburrito88 · 25/04/2025 07:13

SausageRoll90 · 25/04/2025 07:06

Similar here with the constipation. That's my mission this week is to get things moving better in the hope it helps.

I've not previously considered doing anything with the golden dose but part of my is wondering about using some of the golden dose at my 4th injection to boost it to 3.75mg before moving to 5mg in week 5 🤔 because if I still get very little weight movement in week 3 I don't really want to just do another 2.5mg knowing it's not enough for me... I'm not 100% on this idea yet as I had planned just to stick to the recommendations of dosing but I feel frustrated this morning with slow progress this week.

Yes I’m frustrated too. I may also try a slightly higher dose next week as a bridge to going up to 5mg.

TC4 · 25/04/2025 08:04

So I’ve just done my official weigh in for this week although I weigh daily Fridays is official weigh day and jab evening, 2.4kg off this week

28/03 Starting 99.3kg
04/04 Week 1 96.9kg -2.4kg total loss 2.4kg
11/04 Week 2 94.7kg -2.2kg total loss 4.6kg
18/04 Week 3 95.7kg +1 total loss 3.6kg
25/04 Week 4 93.3kg -2.4kg total loss 6kg

6kg loss in a month (13ish lbs)

i was planning on going up to 5mg tonight but I hadn’t quite seen the numbers written down and I don’t want to lose too rapidly (2.4kg in a week is about 4 or 5lb - is that too quick, I was hoping for 1-2lb) because of health implications and sustainability so now I don’t know what to do, unless I do one week of 5 and if it’s to fast or to much I can drop it the week after 🤷🏼‍♀️🤷🏼‍♀️ any advice??

fox919 · 25/04/2025 08:08

Jab day for me too, w3d1

SW - 13st 11.8lbs
CW - 13st 6.2lbs
Total loss - 5.5lbs
Approx 2.5lbs in w1, 3lbs w2

Woken up this morning with a nasty headache so hoping that will pass quickly. Not sure if it’s maybe because my calories yesterday actually stayed low (850). I’m planning on 2.5 today and next week then (hopefully) the bonus dose will be a bit more than 2.5 so it’s a gentler transition to move up to 5..

wordywitch · 25/04/2025 09:04

I’m W4D2 and am struggling with constipation a bit. Since I started I’ve gone from every day to every 2-3 days which was fine as it wasn’t causing me any discomfort but now it’s getting to 4 days and it’s not great. Think I’ll be going to the chemist for stool softeners this morning, any recommendations for other things to try? Coffee usually does the trick but it’s had no effect 😬

Minuethippo · 25/04/2025 09:14

Can anyone help please? How do you remove air in a syringe when trying to extract a dose from the pen?

Newmum110 · 25/04/2025 09:21

TC4 · 24/04/2025 23:10

It will be for most people - just use whatever syringe you have and draw out the liquid from the red port pull
it back further than you need to so there’s a gap and then before injecting hold straight up right flick the syringe gently a few times to get any bubbles to go to the top and then push the liquid up so there is no longer a gap and the needle is full of liquid - once you have done it a couple of times it will seem so straight forward

@minuethippo it's explained very well here.

Tocktik · 25/04/2025 09:21

Some good steady losses, well done everyone, I think it can be disheartening when it’s not a big loss but 1-2lb a week is better as you’re less likely to be losing muscle.

For those looking at needles for the golden dose I would recommend using luer lock syringes, any random needle to draw the liquid from the pen, and then an insulin needle (yellow base) to inject.
the ones on Amazon will work fine but when you pierce the pen and draw up the liquid you will be blunting the needle a bit so it’ll hurt more when you come to inject it in your skin.
With the above you use the random colour needle on the syringe to draw up the liquid, then change the needle tip to a yellow insulin one and then use that to inject into your subcut areas like stomach/arms.
someone up thread has linked the pharmacy supplies website.

MiamiMimi · 25/04/2025 09:22

I can definitely recommend prune juice in a morning for constipation, works wonders.

Tocktik · 25/04/2025 09:26

Also recommend prunes, I have 2/3 every morning, I get the big pack from Lidl, they last ages

SausageRoll90 · 25/04/2025 09:39

@TC4 You're probably right actually about my cycle. I have PCOS and my cycles are irregular so it's really hard to know exactly where I am. But I track them, so it'll be interesting to reflect back on my progress over the weeks in correlation to my cycle.

Also that's an amazing weight loss in 4 weeks!!! I think try the 5mg and see how it goes, as you said, you can always go back to 2.5mg if you prefer.

@fox919 well done on your losses over the last 2weeks... See I can see the achievement when it's someone else but struggle with myself. I need to give myself some credit lol

@Incognitoburrito88 I've made the decision to try to get some of the golden dose for next week. I've ordered some syringes from Amazon 👍🏻 oh I've just seen the post by @Tocktik about needles and ive ordered different ones from that. Oops. Oh well never mind.

Tocktik · 25/04/2025 09:53

SausageRoll90 · 25/04/2025 09:39

@TC4 You're probably right actually about my cycle. I have PCOS and my cycles are irregular so it's really hard to know exactly where I am. But I track them, so it'll be interesting to reflect back on my progress over the weeks in correlation to my cycle.

Also that's an amazing weight loss in 4 weeks!!! I think try the 5mg and see how it goes, as you said, you can always go back to 2.5mg if you prefer.

@fox919 well done on your losses over the last 2weeks... See I can see the achievement when it's someone else but struggle with myself. I need to give myself some credit lol

@Incognitoburrito88 I've made the decision to try to get some of the golden dose for next week. I've ordered some syringes from Amazon 👍🏻 oh I've just seen the post by @Tocktik about needles and ive ordered different ones from that. Oops. Oh well never mind.

Edited

You’ll be fine with the ones from Amazon, they’ll just hurt slightly more going in, advice was more aimed at those who struggle with needles x

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