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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2025 starters thread 2

987 replies

TheSpoonyNavyReader · 17/03/2025 05:57

Welcome to thread 2 never thought we would be posting so much that we have to start a new thread.

I am still hovering around 12 and a half stone. I have been absolutely freezing to the point I have a duvet on the sofa.

I have had one NSV so far I can zip up my boots and they do not feel tight anymore.

OP posts:
Thread gallery
16
taylorswift1989 · 30/03/2025 09:17

Fatmumslim01 · 29/03/2025 23:27

Sounds like there's quite a few us on on wk2day2 not feeling anything after a good week last week!

Looking at reddit, this is quite a common experience, apparently. Generally, people saying take heart because you see the medication works for you. But 2.5 is meant to be a "loading" dose and not everyone is lucky enough to get the full effects at this dose, and many will have to get to 7.5, 10, or beyond.

I think for me I'm going to try to be patient with it. Stick to the schedule. Keep tracking my food and exercise. Go back to injecting in thigh next week. And hope that the 5mg dose next month will make the difference!

Choirgirl699 · 30/03/2025 09:26

28Spring · 30/03/2025 09:04

Quick Q, for the micro dosing, as I’d like to start having 1:25 per week (due to nausea side effects stopping me from eating enough calories and therefore got no energy to exercise or do anything really!) can you just put the needle cover back on and use the same needle for the second dose or do you order the Mounjaro needle tips from somewhere that fit the end of the pen? Xx

You should always use a new needle as it's no longer sterile once you've used it. Bacteria, risk of infection and sepsis. UKMedi will probably have some.

Hope it does the trick with the nausea!

Van34 · 30/03/2025 09:50

28Spring · 30/03/2025 09:04

Quick Q, for the micro dosing, as I’d like to start having 1:25 per week (due to nausea side effects stopping me from eating enough calories and therefore got no energy to exercise or do anything really!) can you just put the needle cover back on and use the same needle for the second dose or do you order the Mounjaro needle tips from somewhere that fit the end of the pen? Xx

I have these ones with my pen. https://www.thefamilychemist.co.uk/product/pen-needles/
Ordered as part of the starter kit with my 2.5 pen

Needles

Shop our Mounjaro-compatible BD Viva Pen Needles for safe and comfortable delivery. Buy our pack of 90 now for £4.99 from The Family Chemist.

https://www.thefamilychemist.co.uk/product/pen-needles/

CFCmum · 30/03/2025 09:50

I did my golden dose on Friday with a syringe and woke up yesterday with an itchy red blob and today it has grown! I draw around it in pen yesterday. Anybody else have anything like this?

March 2025 starters thread 2
taylorswift1989 · 30/03/2025 10:13

Take an antihistamine and keep an eye on it. You could contact your provider if you're worried, but I think it's probably just a minor irritated reaction to the jab. If it doesn't go away with the antihistamine then contact your provider and/or GP.

tryingtobesogood · 30/03/2025 10:32

SW: 108.4 (17st 1 lbs)
CW: 104.4 (16st 6lbs)
TW: 87kgs (13st 10kbs) first interim goal

Wk1: 106.1 (16st 10 lbs)
Wk2: 105.2 (16st 8.8 lbs)
Wk3: 104.8 (16st 7.7 lbs)
Wk4: 104.4 (16st 6 lbs)

Total loss weeks 1-4= 4kgs/9lbs

I’m so pleased with that. It felt like nothing was happening some days but bit by bit my weight is going down.

I’m moving up to 5mg tonight. Bit worried about side effects as im on a course tomorrow. Thinking of doing 2.5mg tonight and the other 2.5mg on Weds, just for this week.

TheBossOfMe · 30/03/2025 10:34

Weigh day today - bit disappointed to have shifted very little this week, but think it's a combination of busy social week where it was a bit harder to make good food choices and far too much alcohol, not enough time to exercise, and water retention ahead of period - I definitely look very puffy, which is typical for me. But overall I'm still really happy with progress:

Start of week 4
SW 10st 4.6lb BMI 25.7 (prescribed MJ because of diabetes risk)
CW 9st 11.1 BMI 24.3 - 7.5lb down. (Still overweight because of ethnicity)
GW 8st 6lb BMI 20.9 (low BMI advised as target by doctor)

If I look at loss by week:

W1 5.5lb
W2 1.3lb
w3 0.7lb

Looking at other people's paths online, that seems to be a quite typical pattern when you start with a relatively low BMI, and given 2.5 is supposed to be the starter dose just to get you used to MJ, I'm ok with small and steady. Ideally I'd like to shift closer to 2lb per week, think I need to really focus on exercise next week to make that doable.

Feeling really despondent today emotionally - my useless arse of an ex booked a holiday over Mother's Day with my DD without asking me or her, so I don't have her with me on a day that is actually quite important to me (yes I know it isn't for everyone, but it is for me). So need to resist the temptation to stuff my face comfort eating 😂

tryingtobesogood · 30/03/2025 10:38

@TheBossOfMe oh that’s not nice. What a mean thing to do.

why not do something fabulous just for you, a home spa day, go to the gym or for a long walk, cook something your daughter wouldn’t normally eat.

it’s not the same, but might distract you from the emotional eating

TheSpoonyNavyReader · 30/03/2025 10:44

Morning all

I have had a very busy week, so only updating you all now.

@TryingMJ loving the photos such good progress.

I have moved up to 5mg after last week where I had no suppression at all and could have ate a scabby Donkey if I could. I also started my period last week.

5mg is not for the faint hearted, I have had no appetite and really can’t eat, I feel full all the time, and for the first time I looked in the fridge or cupboard and was totally not interested in anything.

Anyway let’s get to the good things that have happened I have lost another 2lbs

SW 13st 4lbs
CW 12st
TW 9st 7lbs
18lbs lost in 4 weeks

OP posts:
RuthEvershedforPM · 30/03/2025 10:46

Sorry @TheBossOfMe that sucks. Hope you find somethings nice to do.

I have teenagers who have taken ages to get moving this morning and I need to work at 4 so the Sunday blues has kicked in here 😭

TheBossOfMe · 30/03/2025 11:00

tryingtobesogood · 30/03/2025 10:38

@TheBossOfMe oh that’s not nice. What a mean thing to do.

why not do something fabulous just for you, a home spa day, go to the gym or for a long walk, cook something your daughter wouldn’t normally eat.

it’s not the same, but might distract you from the emotional eating

Thank you - am going to see my Mum, who isn't too well so hopefully I can cheer her up a bit. I live near Columbia Road Flower Market, so have already been up there and bought armfuls of lovely flowers which I'm about to arrange into a bouquet for her (I did a floristry course last year just so I could learn how to make some pretty arrangements from the super cheap flowers there). I'll get on the Tube one step further out and do the same thing on the way back to get my steps in, it's a lovely day in London and I want to be in the sunshine for as much of it as possible

Happy Mother's Day to all the mums on this thread. Such a supportive place, loving it.

Illbefinejustbloodyfine · 30/03/2025 11:53

@soupforbrains really hope the split dose helps!

@TheSpoonyNavyReader thats an amazing result in 4 weeks! did you suffer any horrible SE with the increased dose? I've not had anything terrible so far on 2.5 but the fear of SE is real!

LordGaGaisasahd · 30/03/2025 12:19

Wk 3 Injection 3 (2.5 mounjaro)

SW 11st 10lbs
CW 10st 12lbs

Oh my god I feel awful today! 😱

Took 3rd Injection on Thursday and since yesterday I've had sulphur burbs and horrible diarrhoea. Along with stomach cramps and nausea. I can barely eat anything and feel awful.

Anyone else had this and come out the other side?

soupforbrains · 30/03/2025 12:32

I get this every week the day after I inject. I have found a few things that help. Firstly, eat 5 or 6 tiny meals a day so that you always only have a small amount of food in your stomach. The sulphur burps are caused by food fermenting in your stomach as there’s more food in it than the drugs allow to be processed out due to the way it slows down metabolism. Additionally eat PLENTY of fibre so that it helps keep your system moving.

lastly make really sure not to eat ‘too much’ or any big meals, fatty foods or acidic foods in the day before or of your injection.

best of luck!

Gotitok · 30/03/2025 12:35

Just wondering if anyone could help…last night I went out with friends and had 3 glasses of wine. Around 3am I woke up feeling rubbish and not long after threw up once. I felt fine afterwards and managed to go back to sleep. This morning around 10am I started with stomach ache and had one bout of diarrhea. I feel fine now, managed to have a drink and something to eat. I really don’t think it’s a bug, I’m guessing it’s to do with the jab?

I am going on holiday in 2 weeks and would like to be able to have some drinks but I don’t want a repeat of last night. Could I have a break from it leading up to and while I’m away? I’m also wondering about the fact that the pen can’t be used after 30 days

SpunkyKhakiScroller · 30/03/2025 12:41

First weighing day today. I am super happy!

SW: 106.6kg (16st 11lb)
CW: 103.4kg (16st 4lb)

Wk1 loss: 3.2kg (7lb)

I had a lot of suppression though it was wearing off slightly by the end. And very little food noise. And only very minor side effects - bit of nausea, occasional headache. Will take the second jab in a bit but hope next week is the same in terms of side effects. 102.2kg has been the lowest I have been in the past 4 years. I'd really like to get to that in the next week or two. Fingers crossed.

TheSpoonyNavyReader · 30/03/2025 12:54

Illbefinejustbloodyfine · 30/03/2025 11:53

@soupforbrains really hope the split dose helps!

@TheSpoonyNavyReader thats an amazing result in 4 weeks! did you suffer any horrible SE with the increased dose? I've not had anything terrible so far on 2.5 but the fear of SE is real!

The only side effect I had was constipation and some with slight nausea that only last a matter of hours.

I now drink Kafir yoghurt drink every morning which has helped things along. It is also full of protein.

OP posts:
soupforbrains · 30/03/2025 13:03

@Gotitokyes it’s almost certainly due to the MJ. Not everyone feels I’ll effects from alcohol but all the advice around mounjaro is to avoid spicy, fatty and acidic foods. Wine is VERY acidic so it probably just didn’t go well sat in your stomach.

don’t worry too much just try to avoid more than a single glass in a sitting for the time being.

CarouselQueen · 30/03/2025 13:56

Gotitok · 30/03/2025 12:35

Just wondering if anyone could help…last night I went out with friends and had 3 glasses of wine. Around 3am I woke up feeling rubbish and not long after threw up once. I felt fine afterwards and managed to go back to sleep. This morning around 10am I started with stomach ache and had one bout of diarrhea. I feel fine now, managed to have a drink and something to eat. I really don’t think it’s a bug, I’m guessing it’s to do with the jab?

I am going on holiday in 2 weeks and would like to be able to have some drinks but I don’t want a repeat of last night. Could I have a break from it leading up to and while I’m away? I’m also wondering about the fact that the pen can’t be used after 30 days

Doesn't sound fun! I've not had any difficulties with alcohol (yet) but I'm not really getting anything in terms of effects from the MJ to be honest. I am 3 injections in so guessing maybe nothing will happen until I go up in strength. Haven't lost any weight this week and have generally felt starving.

I'm on a "big" holiday from the end of this week and I am planning on skipping one week - seems unlikely but I don't want to fret about SE starting while away, I'd like to be able to eat some local foods while away and in terms of timescale it isn't going to make a big difference. So I'll probably do one more week of 2.5 when I get back and then move up to 5 and see what happens.

Fatmumslim01 · 30/03/2025 16:38

Well after me saying yesterday that I wasn't feeling any suppression after jabbing on Fri, today the suppression has come back to bite me on my rather large bum 🤣

Just been out for a mother's day meal, set menu 3 courses and I barely had a quarter of each course and I'm uncomfortably full now!

Bipaloss · 30/03/2025 17:23

Just did my 4th jab and some liquid came out (a few drops sort of amount) with a bit of blood. I’m worried I didn’t get the full dose as I’m moving up to 5ml next week and worried that if I didn’t get the full dose that I’m going to have less suppression this week and massive SE next week. Has this happened to anyone else or have advise 🤦‍♀️

Illbefinejustbloodyfine · 30/03/2025 17:35

Bipaloss · 30/03/2025 17:23

Just did my 4th jab and some liquid came out (a few drops sort of amount) with a bit of blood. I’m worried I didn’t get the full dose as I’m moving up to 5ml next week and worried that if I didn’t get the full dose that I’m going to have less suppression this week and massive SE next week. Has this happened to anyone else or have advise 🤦‍♀️

I've read a few people say this, and it's apparently normal. It happened to me last week but I think I injected a bit too quickly. Still had excellent effects.

Wouldratherbewatchingmafs · 30/03/2025 18:17

I'm a bit worried about next week's injection. This week is my last 2.5mg injection and I now have a batch of 5mg injections waiting for me in the fridge.
I'm experiencing quite strong suppression, to the point I'm worried about the side effects of 5mg.
Has anyone given themselves a half dose of 5mg? Kicking myself I didn't just order another round of 2.5mg injections :(

Loveab123 · 30/03/2025 18:46

Gotitok · 30/03/2025 12:35

Just wondering if anyone could help…last night I went out with friends and had 3 glasses of wine. Around 3am I woke up feeling rubbish and not long after threw up once. I felt fine afterwards and managed to go back to sleep. This morning around 10am I started with stomach ache and had one bout of diarrhea. I feel fine now, managed to have a drink and something to eat. I really don’t think it’s a bug, I’m guessing it’s to do with the jab?

I am going on holiday in 2 weeks and would like to be able to have some drinks but I don’t want a repeat of last night. Could I have a break from it leading up to and while I’m away? I’m also wondering about the fact that the pen can’t be used after 30 days

When I've had events I've delayed the jab, so it would be 5+ days since I last jabbed, and I've been absolutely fine when drinking. Due to different things I have on my pen will be longer than 30 days in the fridge. I'm not overly worried but I know it's not recommended. It's just a personal choice to do this.

taylorswift1989 · 30/03/2025 19:44

Wouldratherbewatchingmafs · 30/03/2025 18:17

I'm a bit worried about next week's injection. This week is my last 2.5mg injection and I now have a batch of 5mg injections waiting for me in the fridge.
I'm experiencing quite strong suppression, to the point I'm worried about the side effects of 5mg.
Has anyone given themselves a half dose of 5mg? Kicking myself I didn't just order another round of 2.5mg injections :(

I haven't done it (still only on week 2) but I think it would be fine to half the dose. Maybe try the 5mg split into two doses with four or five days in between, so you're building up a bit but not too drastically? But if you're getting good results on 2.5 then no reason to increase the dose.

Is it too late to order a 2.5mg pen and save the 5mg one unopened in the fridge?