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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2025 starters thread 2

987 replies

TheSpoonyNavyReader · 17/03/2025 05:57

Welcome to thread 2 never thought we would be posting so much that we have to start a new thread.

I am still hovering around 12 and a half stone. I have been absolutely freezing to the point I have a duvet on the sofa.

I have had one NSV so far I can zip up my boots and they do not feel tight anymore.

OP posts:
Thread gallery
16
Fatmumslim01 · 29/03/2025 18:06

taylorswift1989 · 29/03/2025 17:29

I had my second 2.5 dose this morning and don't really feel it. Disappointed, because last week was so good. I did inject in a different place (stomach rather than thigh) but not feeling anything. Surely if I felt it last week, I should feel it more this week, as it builds up in my body?

Feeling a bit dejected! I've still stuck to my calories but could easily have eaten much more.

@taylorswift1989 I feel exactly the same today wk2day2 and no suppression at all, getting by on sheer willpower today! I deliberately chose a Fri for jab day so I'd eat less over the weekend as we tend to eat more on a weekend! And last week I had suppression for the first 4 days but it's been about 30 hours post jab now and I feel the same tbh

ShineyGreen · 29/03/2025 18:08

PoundsLost · 29/03/2025 16:53

I am so not suppressed. Sigh. I’m trying to stick to protein and low calorie stuff when I’m at home but we’re out quite a lot at other people’s houses and I can’t obviously choose what to eat. I HOPE that when I go up to 5mg, something will happen. It feels like such a waste of money.

Edited

I was exactly the same for a couple of weeks @PoundsLost, the odd flash of it but nothing consistent and although I lost weight this was down to willpower and the normal motivation at the start of a new diet. I would have lost weight without MJ I think.

Week 3 was revolutionary- it kicked in and I finally got what everyone else was talking about. So much so that I ordered another pen at 2.5mg. Did jab 5 last night and hoping the next 3 jabs are equally as effective. Hang in there- which week are you on?

SW- 17st 0lbs
CW- 16st 4lbs
TW- 11st 4lbs

Week 1 -3.5lbs
Week 2 -4lbs
Week 3 -1.5lbs
Week 4 -1.5lbs
Total lost - 10.5lbs

taylorswift1989 · 29/03/2025 18:27

Menopants · 29/03/2025 18:05

I just posted the exact same thing!

I wonder why that is! I'm hoping it's to do with the injection site. Will go back to the thigh next week and hope it works. Otherwise I guess it's needing to go up to 5mg and try that...

PoundsLost · 29/03/2025 19:15

Oh your post gives me hope @ShineyGreen - though I didn’t lose even a 100g during week 1.

I’m wk 2 day 3 and still nothing - I do appreciate that I have no side effects at all - but they would be evidence! I might as well be injecting water! Completely regular, feel good as usual, entirely happy having some wine.

Reading other posts, I will try my thigh next week as the injection site and see if that makes any difference.

ShineyGreen · 29/03/2025 19:39

Ooh yes thigh- weeks 1 and 2 were in either side of my stomach but weeks 3 onwards have been in l/r/l thigh. I jab just before bed and when I woke up this morning I forgot to eat (forgot!!!!) until mid afternoon and that was only because I went food shopping

taylorswift1989 · 29/03/2025 19:55

Oh man I wish I'd stuck with the thigh jab!

I might bring my next jab forward. The leaflet says to leave at least four days between jabs, so maybe I'll do it on Tuesday evening.

Loveab123 · 29/03/2025 20:12

taylorswift1989 · 29/03/2025 19:55

Oh man I wish I'd stuck with the thigh jab!

I might bring my next jab forward. The leaflet says to leave at least four days between jabs, so maybe I'll do it on Tuesday evening.

When you jab in the thigh where do you jab? I'm thinking of trying the thigh tomorrow. Thanks.

ShineyGreen · 29/03/2025 20:15

I do it front of thigh. Think I read it somewhere in the literature but could be wrong!

Yellowsubmarine55 · 29/03/2025 20:29

Everyone thinking of changing to thigh, what are you missing in stomach? Due jab 2 soon and was hoping thigh may give me less side effects....

Bubbless31 · 29/03/2025 20:30

Hi all, ive got my pen in the fridge and am ready to do my first jab tomorrow.. any advice or just jab it and hope for the best?! I’ve read 20 odd pages so far but feeling nervous…

taylorswift1989 · 29/03/2025 20:38

Loveab123 · 29/03/2025 20:12

When you jab in the thigh where do you jab? I'm thinking of trying the thigh tomorrow. Thanks.

In the fat at the top of my thigh.

taylorswift1989 · 29/03/2025 20:39

Yellowsubmarine55 · 29/03/2025 20:29

Everyone thinking of changing to thigh, what are you missing in stomach? Due jab 2 soon and was hoping thigh may give me less side effects....

I think there's a lot of individual variation tbh!

Ally638 · 29/03/2025 20:49

i haven’t 💩 since my first MJ day so Wednesday. This is day 3 no 💩 any tips? I’ve been drinking soooooo much water, like 3-4litres and trying to eat veg like broccoli with each meal and lots of protein and fibre.

also, I’m confused about the weight exercise you’re supposed to do. The issue I’m overweight is lack of time. Lack of time to prepare good snacks, lack of time to exercise, lack of time to relax so I’m always stress eating. MJ has helped stop the stress eating and snacking so I’m just eating my meals really, but I still don’t have time to exercise. I’ve read about muscle and bone damage wastage - so, if I don’t have time to exercise am I better off just staying fat, or is there something specific about MJ that makes you lose muscle and bone density which WOULDNT happen on a normal low calorie diet?? TIA xx

Illbefinejustbloodyfine · 29/03/2025 21:05

Bubbless31 · 29/03/2025 20:30

Hi all, ive got my pen in the fridge and am ready to do my first jab tomorrow.. any advice or just jab it and hope for the best?! I’ve read 20 odd pages so far but feeling nervous…

Give yourself plenty of time. Read the instructions a couple of times. When you twist the end of the pen, to get the first dose, you have to twist it a LOT (I had no idea....)

Good luck!

Bipaloss · 29/03/2025 21:49

Ally638 · 29/03/2025 20:49

i haven’t 💩 since my first MJ day so Wednesday. This is day 3 no 💩 any tips? I’ve been drinking soooooo much water, like 3-4litres and trying to eat veg like broccoli with each meal and lots of protein and fibre.

also, I’m confused about the weight exercise you’re supposed to do. The issue I’m overweight is lack of time. Lack of time to prepare good snacks, lack of time to exercise, lack of time to relax so I’m always stress eating. MJ has helped stop the stress eating and snacking so I’m just eating my meals really, but I still don’t have time to exercise. I’ve read about muscle and bone damage wastage - so, if I don’t have time to exercise am I better off just staying fat, or is there something specific about MJ that makes you lose muscle and bone density which WOULDNT happen on a normal low calorie diet?? TIA xx

Prunes is your best friend , I only got mild constipation first week and Frye prunes from Lidl made the trick. I eat 4 a with my evening meal and now go every morning (TMI but it’s very different to before not loads but appears to be heavy as difficult to flush) had a what I call a tummy rinse week 2 day 5.

I didn’t feel like exercising first two weeks as I was eating a lot less then previously and was adjusting. Tried a Zumba class on Tuesday and was struggling not because of the excessive but I was really low on energy and thought I was gonna faint. Body is getting adjusted and I think next week I will increase excesses.

i try to prioritise protein and fibres and as I go on I will aim for weights and PT as get closer to my goal weight (I still have 5st to loose so I’m in for the long term)

I think all this is trial and error and week by week .

popdepop · 29/03/2025 22:23

@menopants @taylorswift1989 I'm the same. W2D2, nothing. I'm really hoping it kicks in again.

Fatmumslim01 · 29/03/2025 23:27

Sounds like there's quite a few us on on wk2day2 not feeling anything after a good week last week!

AmateurNoun · 30/03/2025 00:25

Bubbless31 · 29/03/2025 20:30

Hi all, ive got my pen in the fridge and am ready to do my first jab tomorrow.. any advice or just jab it and hope for the best?! I’ve read 20 odd pages so far but feeling nervous…

I did my first dose on Wednesday and found this video much clearer than the instructions:
https://vm.tiktok.com/ZNd8DPkLB/

I am down over 3 pounds so far. I am aware that a lot of that will be water but my body fat is down from 38.3% to 38.1% so some of the fat must be coming off! So far it has been scary administering the medicine but worth it. I was particularly nervous about giving myself an injection and I am hoping I will get used to it over time.

soupforbrains · 30/03/2025 03:40

So today (Saturday) was my final weigh in day on my first pen.

I only lost 1lb this week. But I definitely did a lot of emotional eating. And, because I was eating rubbish instead of my usual foods, I’m a little ‘backed up’. So although it’s a smaller loss than previous weeks I’m not too disheartened.

End if week 4
SW 19st10
CW 18st8
GW 11st10

I've lost a total of 1st2lb (16lb or 7.25kg) in my first 4 weeks. So I’m definitely happy overall

I injected my first dose from pen 2 today. Due to my issues with side effects I chose to remain at the same 2.5 dose. And I also bought extra pen needle tips so that I can split my doses to see if I can avoid the post injection side effects. So today I actually injected half a dose with a view to injecting the other half in a few days. I’ll let you all know tomorrow if I’ve managed to avoid vomiting!

I'm happy not moving up to 5mg so long as the weight loss continues steadily. If the weight loss slows then I’ll go up the dose next pen, but I’ll have to do a 1/3 dose injection every couple of days I think. (If the dose splitting works for me side effects wise.)

Justformounjaro · 30/03/2025 06:43

Well, I made a mistake with my golden dose 🥴

I decided to go for it last night after coming back from our meal out. I tried breaking the pen, which seemed to work but then nothing would come out. Then I had great difficulty extracting enough of a dose without air bubbles. By the time I had, the needle on the syringe was bent to one side and it was probably too blunt to use but I didn’t know how to transfer the contents to another syringe so I definitely felt this one going in when I injected.

And then, this morning, I’ve woken up with diarrhoea 😳

I should have waited till the food and wine were out of my system; it was definitely the wine that talked me into keeping to the schedule and probably didn’t help extracting the dose.

Now I’m feeling that “clocks changed - what time is it really just now” thought process.

Justformounjaro · 30/03/2025 06:45

You’ve done so well @soupforbrains, and it was still a loss, albeit small. I hope the new injection regime works for you.

Flipper1234 · 30/03/2025 07:03

Just about to start pen 2 - 5mg

SW 191lb
Week 1 loss 6lb
Week 2 loss 2.5lb
Week 3 loss 2lb
Week 4 loss 1.5lb
CW 178lb

Loss so far 13lb

Illbefinejustbloodyfine · 30/03/2025 09:02

End of wk 2 weigh in
SW 17st 2
CW 16st 2
GW 11st 7
Total loss 1 st. Disclaimer, changed scales, these weigh 2lbs lighter but I'm sticking with them going forward. So in reality a 6 25lb loss. Scales saying 8.25.

So so pleased. Fingers crossed for a 15 next week. 3rd dose this evening.

Bipaloss · 30/03/2025 09:04

SW 115 kg/ 18.1 st

Week 1 loss 2.2 kg /4.8 lb
Week 2 loss 1.3 kg/ 2.8 lb
Week 3 loss 0.4 kg / 0.8 lb

CW 111.1 kg/ 17.49 st
total loss 3.9 kg / 8.59 lb

disapointed with the loss this week so ordered a 5 pen for my next one (dose due next week). Also it’s the time of the mont next week so could some water retention but with minimal side affects I decided it’s time to move up.

28Spring · 30/03/2025 09:04

Quick Q, for the micro dosing, as I’d like to start having 1:25 per week (due to nausea side effects stopping me from eating enough calories and therefore got no energy to exercise or do anything really!) can you just put the needle cover back on and use the same needle for the second dose or do you order the Mounjaro needle tips from somewhere that fit the end of the pen? Xx