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Having trouble conceiving? This Infertility Support forum is a safe space where Mumsnetters can connect with others in the same position, discuss causes, treatment and IVF, and share their infertility stories of hope and success, from our caring community.


IVF cycle buddies June/July

441 replies

Hobbes39 · 30/05/2017 12:09

Hi! I'm hoping that this is 3rd time lucky for us... due to start process for my first Frozen transfer in June, with the actual transfer being in July... anyone want to join me on the journey? We have 2 unsuccessful fresh cycles behind us, and I have this one single little embryo from the last cycle sitting in the freezer waiting for me. It's a 3BB and all my hopes are pinned on it being the one!
We have unexplained secondary infertility, have a DS who will be 4 in August, and I've just turned 40, so time isn't on our side... so I'm now waiting for my period to start (due in about 10-14 days, although my cycles are mucked up since our ivf failed in April)... but once it comes i will be down regged to them do transfer early July I think! Fingers crossed we get lucky this time...!

OP posts:

geeup · 16/08/2017 08:13

Hi everyone. I wondered how those of you whose cycles failed are doing and if you have a new plan? I'm still in limbo waiting for AF so I can get going with my FET but some days I wonder if I should take the rest of the year off to lose some weight and chill out but I want to get pregnant so much. I'm just aware I've been doing back to back ivf since March and it's so stressful. I keep dreaming I'm pregnant but that I start bleeding again. Sad


Pyjamas81 · 16/08/2017 08:24

Hi geeup - I started stimming again on Saturday (on short protocol) and am currently sitting in waiting room for first scan after starting meds. They upped my gonal f dose from 300 to 450 this time. I know what you mean about wanting a break! Part of me thinks I should've had a longer break, but the other part just wants to get pregnant!

Hope the limbo ends for you soon xxx


geeup · 16/08/2017 17:51

That's exciting. How did you scan go? How are you feeling?
I was so much more relaxed on my second cycle. Are you? The first time I ate a regimented regime, didn't drink, stayed in and didn't socialise, took 2 weeks off work, worried constantly about drinking Pom juice and castor oil packing my uterus but was a bfn. The second cycle I knew what was coming and I didn't change my life - ate normally, went to work, had a drink or two and forgot to castor oil pack or put legs up the wall a single time and got a bfp (although it obviously couldn't stick around). My mental health felt way better on the second one!
I think I've come to terms with the fact that if it's going to stick, it'll stick. What we do has little impact...


Pyjamas81 · 17/08/2017 11:46

Scan went ok - 7 follicles which is 2 less than last time which is annoying as I'm on a higher dose of gonal f, but am trying not to let it get me down! I'm experiencing a few more side effects this time - moodiness, bloating etc, which I'd be fine with if I could see it was making a difference!

I'm weirdly finding this cycle more difficult than the first one - at least with the first one I had the excitement of doing something new, and now all I feel is fear of the end because I know how much it's going to hurt if it doesn't work :(


LoPl · 21/08/2017 15:21

Hey, just seen these new posts. Good luck you two. I'm taking a little break. Third BFN really hurt, and the numbers (eggs produced and fertilised don't exactly give me much hope for a further go). We're going for more tests to rule other health things out and then may give it one final bash nearer Christmas. xx


geeup · 21/08/2017 20:54

Good to hear from you LoPi and sounds like a good plan. We haven't ruled out doing a break too as we are flying long haul in November so can't fit a FET in before then without flying in first trimester. Can't work out how I'd feel if I got a bfp then miscarried after I flew. I think I'd put it down to the development of the embryo but maybe the flying would make me feel guilty...


LoPl · 21/08/2017 21:59

Yeah, I think it's really in the lap of the gods regarding if they develop or not - but it's important to recognise that you may not be able to think this clearly during the process... and have no regrets about what you do or don't do.


Hobbes39 · 28/08/2017 22:17

Hi LoPI and Gee - just seen your updates - hope you guys are doing ok? We too are going for more tests... my clinic don't offer immune testing, but have an appointment tomorrow for a consultation with GCRM who do, so going to ask them about it. The way I see it is that while we can't test for egg quality, we can test for most other things, and if they come back clear then it can only be old duff eggs... what tests are you thinking of LoPI? Good luck to you all with next steps x

OP posts:

geeup · 31/08/2017 07:06

How did your consultation go about immunes hobbes?
Hi everyone. Sorry I've been quiet. We've decided our plan for the FET now. I'll be starting downregging when I get AF at the beginning of Nov (8 weeks away ), and having the transfer at the beginning of Jan. Urgh the process takes so long. We're working it around a long haul flight in Nov. The clinic said they wouldn't want me to fly if I got a bfp so we can't transfer till after that. The things we are doing are: scratch (again), aspirin (again, but this time only from when I start oestrogen tablets), transfer 2 embryos this time and then progesterone pessaries 3 times a day instead of 2 times. In the meantime I'll focus on work and losing some weight ideally before my holiday! God I hope that combination works as now even my two friends that were fellow infertile too have got pregnant so it's only me left with no baby Sad


Hobbes39 · 31/08/2017 21:56

Hi Gee - consultation was good and bad - basically the consultant we saw said he doesn't think the immune testing is worth it - it is 'unproven despite extensive research' according to him... I asked why the hell their clinic then offer it and he said 'I personally don't think we should' Shock.
So that was disappointing. He did however say that from looking at my numbers and previous rounds that he thought it 'likely that we would get pregnant eventually' depending on how many more times we were prepared to go through the whole thing, as he thinks the same as we have been told at our current clinic - we have 'just been unlucky' so far. Sad. So we are off on holiday tomorrow and when we get back we will have our follow up appointment with our clinic and see what they say and we will probably go again with wherever can do it fastest... if we don't give it another go I will never forgive myself, but I don't know how much more we can take... hoping for a miracle natural baby in the mean time! X

OP posts:

geeup · 01/09/2017 07:49

That's really interesting. My clinic said the same - expensive and unproven (they don't offer it though). In fact my consultant said someone died after it so they would actively advise against it. Tough when my friend just got pregnant after immunes at another clinicHmm he did say however that the intralipids are basically soy flavonoids (I think that's correct) and effectively are like taking oestrogen. Something like that anyway. He spoke to us for ages - well over an hour - about every piece of research out there globally for the past 30 odd years and said as a result the only actual evidence based recommendations with randomised placebo trials should be the scratch and possibly aspirin and slightly possibly heparin (although he is still on the fence with that and didn't recommend).


Hobbes39 · 01/09/2017 08:23

Gee - very interesting - ours also said scratch could be worth trying, but that was it... and I also have a friend who had multiple failures, then had immune testing and came back with v high killer cells, was on steroids and then got her much longed for baby... I even told him this and he seemed to think that it was probably just down to the numbers that it worked finally for her... I am at least reassured that your consultant said the same thing! X

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LoPl · 01/09/2017 10:28

Hi Hobbes, hi gee-up. That's interesting reading, and definitely reassuring. We are going for a sperm DNA fragmentation test - due to the fact OH's cancer (and surgery) may have caused trauma in the area. If his sperm is fragmented, they may be able to improve it - thus increase our chances of getting good fertilisation/blasts. We will give it another go regardless. But we are having conversations about donor and adoption options now.... as I would like to move forward in some shape or form next year. Hugs to you xx


geeup · 04/09/2017 07:56

Good luck Lopi. We looked into the fragmentation too although haven't gone ahead. Hope it helps you.


Glamm · 03/11/2017 23:54

Hi all, havent been here for long and just caught up on all the posts.. hope everyone is doing well.

I am devastated and been in a right mess ever since this morning. I had the embryo transfer 14days ago.. grade A high quality blastocyst and docs had all my hopes up.. did a home test yestetday, came out negative.. BT confirmed bfn with hcg levels below 1.. i have been told to stop taking meds and wait for AF.. so gutted.. i only had 5 frozen and it just feels like if the top quality one didnt make it, what hope do I have.. i just feel like crying it out loudly and getting over it so I can prepare for round 2 but I am so drained right now. Nurse said I will have to wait 2cycles before I can start again but the waiting list is huge due to xmas break.. so i might be looking at mid next year.. i feel like the wait is going to make me go mad.. a lot of you are going through SO much and I really wonder how you do it.. i really take my hats off to u guys.. its my first IVF and I feel like I have been on the scariest maddest roller coaster for the last one year and all that for nothing at the end :( .. so disappointed


geeup · 04/11/2017 08:41

Really sorry to hear your news @Glamm it is devastating. I can certainly reassure you though. A friend got pregnant with a 3 day embryo that the doctors said wasn't worth putting back (and she'd had failed 5 day perfect blasts) and now she's about 5 months gone. Don't read too much into quality. It's a luck and numbers game.
Lick your wounds and be kind to yourself but then take however long off and get back on the horse. And I say that approaching my third cycle after two failures of perfect hatching blasts. Good luck and sorry again - I know it's so so sad.

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