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Infertility
IVF cycle buddies June/July
Hobbes39 · 30/05/2017 12:09
Hi! I'm hoping that this is 3rd time lucky for us... due to start process for my first Frozen transfer in June, with the actual transfer being in July... anyone want to join me on the journey? We have 2 unsuccessful fresh cycles behind us, and I have this one single little embryo from the last cycle sitting in the freezer waiting for me. It's a 3BB and all my hopes are pinned on it being the one!
We have unexplained secondary infertility, have a DS who will be 4 in August, and I've just turned 40, so time isn't on our side... so I'm now waiting for my period to start (due in about 10-14 days, although my cycles are mucked up since our ivf failed in April)... but once it comes i will be down regged to them do transfer early July I think! Fingers crossed we get lucky this time...!
Glamm · 21/07/2017 10:13
Hey gee, i see what you mean though I still dont know how many will make to freeze. Clinic has decided to do a frozen ET since apparently, my body was hyper stimulating. So I will have to wait 2cycles and a further 7 weeks for prep before I can finally see some results. Hopefully I would know how many of my eggs made it to blastocyst on Monday. So anxious 🙈
LoPl · 21/07/2017 11:36
So I'm still at 5 follicles. Despite them boosting my menopur dose to 450 the little ones don't want to catch up at the moment. However, given what happened last time - they are stretching me out another few days... EC was anticipated for Mon, but it's now looking like Wed... it's starting to feel proper swinging down there 
Hobbes39 · 23/07/2017 22:51
Hi all, hope everyone has had a good weekend? I've been really busy with family staying so thankfully been able to take my mind off things a bit, but it's always there isn't it? I'll be 7po5dt tomorrow, which is the equivalent day I have got my period both my fresh cycles, so I'm getting increasingly nervous... I feel nothing much although started to feel a bit crampy this eve, so not sure it's looking good, but I'm still clinging on at the moment.
Glamm - good luck for tomorrow, 9 embryos is a good number, fingers crossed for you that you'll get a good handful making it to freeze x
How's everyone else doing? X
Hobbes39 · 24/07/2017 07:59
Thanks Gee - no blood this am yet, but I'm not feeling very hopeful as I am definitely crampy and have no other signs of it having been successful yet - no tender boobs, nothing. I suspect that the higher dose of progesterone this time might actually be keeping my period away, but we will see. I don't know if anyone else is on cyclogest? Apologies for tmi but I've def noticed in last few days that they are much harder to get in than they were, which I think must be because my cervix seems VERY low... which isn't a good sign either as far as I know. But it ain't over yet! X
LoPl · 24/07/2017 08:45
Oh good luck Hobbes. Everything crossed for you.
And good luck too Glamm - 9 embies is great.
About to go for what is - hopefully - my final scan. But woke up worried this morning - as I developed a very red, itchy rash on my foot on Sat, which is spreading... Reaction to some of the drugs? A little freaked out, and upset that I don't seem to be in optimum health for EC. Can you even take antibiotics while cycling?
geeup · 24/07/2017 09:34
Haven't heard of that Lopi but hopefully it's not related.
Hobbes - how many cyclogest are you on? I took them (back door so can't comment on the low cervix thing I'm afraid) - 1 pessary in morning and 1 in evening. Is that what you're on? My DH is convinced I need a higher dose to stop my period coming at 5dp transfer.
Hobbes39 · 24/07/2017 18:55
LoPI -hope you are ok? Sounds itchy! Hopefully it's just a skin reaction to something and will go away asap - not what you need!
Gee - I'm on the same cyclogest as you then - one in morning one at night... horrible leaky stuff..! I have been on near constant knickerwatch today and driving myself insane as feel like period is coming, but nothing yet. Don't want to get hopes up, as obviously I still have 2 days to go, but at least making it beyond the morning of equivalent of 12dpo is progress! I fee like if I write this, I will immediately get my period afterwards, but if it doesn't show it's face by tomorrow morning, I am considering testing, but am really torn as will be so so gutted if it's negative, kind of want to cling on to the fantasy for a bit longer.. 🙈.
Blood test is due on Wednesday morning, so not long I guess but not sure I can cope. I am peeing about 30 times a day as of today as I'm constantly checking to see if it's all over... it's ridiculous how insane this process can make you isn't it?
Glamm - hope you had good news today?
How's everyone else? X
geeup · 24/07/2017 19:09
Peeing lots sounds good!! Sorry if you've already done this but can you talk me though the process for a FET. Is it:
Day 21 start buserlin and scratch if you're having one
Day 28/1 start period (ish)
Day 3 scan/start oestrogen for about two weeks
Day 14/15ish start progesterone
Day 16/17ish put back the blast?
Hobbes39 · 24/07/2017 19:39
Hi Geeup - I think as with all things IVF it varies with each clinic and each person, for me as my periods were a bit off after the fresh cycle they gave me the down reg injection on day 2 of my period. If you are regular then I think they give it on day21.
I had a single big injection for 'slow release' drug (basically the same as buserelin but one injection at the start, instead of lots of little ones - think they do this as they don't need/want to stimulate ovaries later in an FET obvs). I was on them for 3 weeks, then scanned to see if lining was thin enough, and as it was I then started the estrogen. Then after 2 weeks of that, they scanned to see if lining was now thick enough and as it was I was then booked in for transfer the following week, and they counted back from that day to 5 days beforehand (as my embryo was a day 5) and I started cyclogest alongside the estrogen from then, then embryo popped back in again and here we are a week later... 🤞 Hope that helps? How are you getting on? X
Hobbes39 · 25/07/2017 06:54
So no bleeding yet, so I tested this am... which I wish I hadn't as it was negative. 
I'm only testing 1 day early (8dp5dt) so I'm pretty confident it's accurate. Just so fed up, why are we never the lucky ones? Fuck. Blood test is tomorrow so will be confirmed then.
LoPl · 25/07/2017 08:20
Oh Hobbes - I'm sorry about the test. I really hope its not accurate, and there is still some hope given that your period hasn't shown up 
I'm off to the GP now - my foot is an itchy balloon. I haven't slept all night. I'm clearly having some sort of allergic reaction - but the nurse yesterday didn't think it was to the drugs. I'm also now at risk of overstimulating as they have kept me on drugs that little bit longer - so I feel very crappy, but I hope it will be worth it. EC on Wed.
Glamm · 25/07/2017 10:11
Hobbes - so sorry for u to be going through this tensed time... i really hope things change by tomorrow. I know its easy said than done but try n relax and think positive. A lot can change in 24 hours. All the best for ur scan tomorrow. Keeping my fingers crossed for u x
Lopi - what did the gp say about ur itching? Hopefully its nothing major x. I can totally relate to the uncomfortable feeling before EC as my dose was put up too and EC was delayed coz follis were too small and not many either.. just around 9-10 and all less than 10mm but 3days later on a higher dose and I couldnt even sit on my bum and constant pain in my underbelly made it so painful to even sneeze. Ouch.. hang in there. It will all definitely be worth the wait.
Nigel - How are you doing lovely? Wishing a beautiful successful journey ahead x
Gee - how are you feeling lovely?
AFM, got a call from nurse yesterday morning. They were able to freeze 5.. blastocysts, 3singles and 2doubles (the bit I didnt really understand much. Anyone?). So she said 3 expanded blastocysts and all 5 are top quality i.e. 3AA, 1AB and 1 BB. I know people end up having a lot to freeze and my number is rather low but l m Very relieved to be honest. Now starts my wait till the ET which isnt for another couple of months.
Really hoping that this week is full of great news for all of u lovely ladies .
Hobbes39 · 26/07/2017 11:13
Hi all, have had blood test - calling for result at lunchtime. Am currently livid though as when I went in to the hospital for the test, I told them I'd tested yesterday as I'd got my hopes up as no period (still no period) and they casually told me then - having never mentioned it before - that 'oh it would be unusual for you to get your period on an FET due to the oestrogen & progesterone drugs you are on, so lack of period isn't a sign either way' 
I'm so flipping angry that they didn't tell me this before as at the very least I wouldn't have been on constant knickerwatch, but also could have prepared myself better. I know the blood test is going to be negative, I know it's not worked and nothing will change that, but the mental side of this whole process is THE hardest thing, and if they don't bother to tell you something as important as "your period is v unlikely to come until you stop the drugs" it makes it tougher than it needs to be. I knew from internet searching that some people don't get period until stopping drugs, but as I've been an early bleeder both fresh cycles I had assumed I could be this cycle too as no one at the hospital though to tell me otherwise....
Anyway, sorry for rant, I'm just gutted and angry and bitter and fed up / depressed that we don't appear to be the lucky ones....and it's grey and miserable weather here too, which doesn't help my mood. 😔
geeup · 26/07/2017 16:29
I'm so sorry hobbes. I totally agree they should educate us more in outcomes and options. I would be exactly like you having bleed at 5days after both my fresh transfers, I definitely have got my hopes up of a bleed hadn't come on my FET. I do really like my clinic but I definitely feel they are so keen to err on the side of caution, they don't actually tell me what's realistic and they don't share latest research/thinking.
I really am sorry. My next step after my FET in September will be immune testing privately - my NHS clinic don't recommend but I feel like I have to do something.
Glamm · 26/07/2017 17:51
Hobbes - so so sorry that you're going through this all.. i havent been a part of this thread for long so I do aplogize if u have shared this information before but have u considered going for a frozen embryo transfer? My clinic says that the success rates are much higher. My clinic has decided to do a frozen transfer for me since it has better success rate. So I had my EC 2 weeks ago and now waiting for the frozen transfer in sep/October sometime... Do forgive my ignorance on the matter as its my first time on an IVF cycle or any treatment for that matter.. I really hope you can try n stay positive. Easy said than done .. tight hugs for you xx
Hobbes39 · 26/07/2017 18:14
Thanks guys.
Glamm & Pyjamas - this was my 3rd time, I've done 2 fresh cycles prior to this, this one was a frozen transfer from the only frozen blast we got, so feeling utterly depressed at it failing again.
Geeup - I am wondering about private Immunes now too - is it something you can just send off a blood sample for or do you need lots of tests? Need to investigate more. Am actually considering looking into serum in Athens as saw that someone on the long term secondary infertility has finally had a BFP after being treated there..?
geeup · 26/07/2017 19:10
I think the immunes testing is around £2k and they take lots of blood samples and test them. Not a small outlay but I figure if I have to go for another fresh round anyway, better to spend £2k up front to not waste another £5kish for a full fresh round to fail again. It's hard though as it is theoretically unproven. It makes sense to me though as I have eczema and asthma and other allergies so seems pretty easy to imagine my body thinks it's allergic to a pregnancy too 
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