Please or to access all these features

Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Ivf anyone starting stimms next week?

523 replies

naty1 · 29/01/2014 21:35

Im starting stimns next week for icsi(dependent on blood test)?
Anyone at the same time want to join.

OP posts:
naty1 · 26/06/2014 20:41

That must be annoying, have you got a timeline in mind like if no donor found by x time you will try another of your eggs?
Everything with treatment seems to take at least twice what you think it will

OP posts:
Shellster52 · 29/06/2014 20:39

I think I should start at the same time as you Nat. Period due 12th July if I have textbook 28 day cycle, but it is usually shorter. Will be so nice to have a cycle buddy - with someone who understands the pain of failure. How are you coping with your sisters pregnancy now? Guess I am just wanting advice for myself if it got easier over time as I just found out my bum brother in law and partner got pregnant with their first while I was going through IVF and just found out yesterday are pregnant with second. Frustrates me they don't work and yet can have children which I have to pay tax to raise. Meanwhile I am trying to save to fund for my own family but have to give away pay in tax to raise their children. Can understand some people have reasons why they can't work, but he is just a bum. Okay, needed to vent about that.

I was wondering how you were getting on Suzy as I clicked on this thread so I am glad you posted. Must be frustrating waiting, although I guess donor egg takes the pressure off the time frame. Did you get any idea as to the average wait time?

suzylee73 · 29/06/2014 22:26

It's been on hold until they get my medical records, but they arrived here on Friday so I just need to sort the relevant bits and email them. Then hopefully it's just a matter of weeks until a donor match Smile
I'm strangely not that bothered about doing it this time, maybe because I have already failed once and in my mind I don't see why this will be different. I have 2 pregnant friends and one couple has a 2 week old and as you both know it's bitter sweet seeing them.
A little voice in my head keeps reminding me that adoption would give me a 100% success rate! I really admire your strength Shellster, 7th time a charm eh Grin

Shellster52 · 02/07/2014 20:33

Not sure about it being strength Suzy. Sometimes I wish I didn't want this so bad so I could stop being IVF obsessed and get my life back. Hopefully its all over with after this one - that sounds to good to be true even typing it.

Yep, totally get the bitter-sweet feeling. Just visited someone with a 3 week old and found out my bum brother in law has impregnated his partner. I'll be raising that child for him from my wages that I will give away in tax. That one really is all bitter no sweet!

Glad you are not so bothered and feeling quite calm. So it could all happen quite quickly once you sort through and email the records. Maybe once it gets going the nerves will start to ramp up. Today is day 20 and I start estrogen tablets today in prep for IVF next cycle and I too am not feeling bothered. I think because after 6 failures, I won't be excited until I make it to egg retrieval without being cancelled for poor response and they then tell me the embryos are great quality.

naty1 · 11/07/2014 19:55

So just 18 days till i start the pill then down regging.
Just have to get call for delivery of the meds.
They asked if i wanted gonal f or menopur.
I explained i have been pushed towards staying on the menopur. The nurse said that dr does prefer it.
But said nhs wont fund gonal f (interesting, dont know why if theyre the same price)
My DSis only has about 12 weeks left. Its taken 5 months to have this go. I expect ill find out the result just when shes due which will be fun :(
Im not feeling very positive

OP posts:
Shellster52 · 13/07/2014 04:27

So you are staying on the Menopur than Nat - despite it giving you less faith in IVF success?
Don't understand your NHS system but I know others on here have a funded IVF cycle and are on Gonal?
Your sis's preg has gone so fast!

My Dsis is pregnant too.

This will be my 7th IVF attempt and I am starting to feel like I have to make a decision to call it quits if it keeps going pear shaped.
Can't imagine dealing with her baby if I am at that point when hers is due.
We just have to forget about it now and focus on ourselves for this cycle.
Okay, my period started today. Start injections tomorrow. Here I go again...

naty1 · 13/07/2014 17:08

Guess it depends on the area of the country.
Yes the months have gone quickly, i would have been halfway though pg if it had worked.
Hoping your follicles grow really well
I dont have much faith either way as i dont know what caused the low number of mature eggs

OP posts:
suzylee73 · 13/07/2014 17:49

I think previous failure takes away your hope, I know I'm not optimistic like I was the first time. I was so excited to get started but this time I just seem to be putting it off.
I don't know where you find the strength Shellster!
Lets hope at least one of us is successful this time :D

Shellster52 · 15/07/2014 04:40

Ew, hello lovely suzy. Every time I see you have posted, I am keen to read and see updates on your IVF. But you sound like no new news yet - or is it you putting it off rather than waiting for a suitable donor?

Yep, you're right. Previous failure takes away our hope. And I have had 6 of the suckers so all I know is failure. I went for a day 3 scan today. 19 antral follicles. Really shows that my research and changes have helped since last year when I started IVF, I would start with 5 to 8 on day 3 and now last cycle I started with 14 and this cycle 19.

But I know lots of women start with this many follicles including yourself suzy and it doesn't guarantee success. So I won't be excited until I see a positive pregnancy test. (That sounds like a fairytale even just writing it). But still, starting with 19 is a good start.

naty1 · 17/07/2014 15:47

Finally got my meds delivered (2hrs late)
Opened up to get the hcg pen ... Found i have gonal f not menopur.
Called clinic they said the error is not with the delivery company and i can get the menopur sent out without extra cost (we shall see)
I did that though i still wonder if should have gone with gonal f because of the pcos and would have done if conultant hadnt said stick with what i had.
I think i probably confused the nurse when i agreed the meds as i was unsure and we discussed it but i know i did say menopur (wondering if she secretly thought the gonal f is better and as i wasnt sure but she didnt like to go against what the consultant advised.

Shell how are the follicles going?

OP posts:
Shellster52 · 17/07/2014 22:43

I hope this whole Menopur instead of Gonal F thing isn't going to leave you wondering 'If only I had of swapped...' if this IVF doesn't work.
My IVF Dr has allowed me to do everything exactly as I want this cycle so that I can at least have peace that I gave it my all. My previous IVF's were at a cheaper clinic and every time something went wrong (couldn't fit me in on appropriate EC date, nervous trainee doing transfer, protocol I wasn't happy with). So this time I have everything I want so I can at least have peace... but of course I am hoping for better than peace. I want a positive test. But so far my method seems to be correct because what I did last cycle has set me up for my record of 19 starting follicles. Getting ready for day 6 scan now to see how many are growing.

naty1 · 18/07/2014 09:10

Good luck

OP posts:
naty1 · 18/07/2014 12:02

Im starting to feel

OP posts:
naty1 · 18/07/2014 12:16

Oops.. Its all going a bit wrong as im stressed, my dad is having an op in august and ive just worked out its when my egg collection will be :( as my mum is driving him and staying overnight so would not be able to babysit DD, so hopefully Pil will help but... Last time mil bought a Lot of cakes etc so im worried ill pig out again and ruin my chances of it working (but also that FIL will need to come too as MIL may also be having op meaning she cant lift DD and he is awful with cakes and sweets etc which will be really stressful.) They even left a load of huge muffins. I just dont think they realise it does not help with the ivf nor i expect DH undiagnosed issue causing low sperm count, which i suspect may be diet related. Though luckily by that stage his part will be done with.
Im not sure how my parents manage it, just my luck . Its a bit annoying as i dont really want anyone here at all at that time but first choice would be my mum, then mil.

OP posts:
Shellster52 · 22/07/2014 08:25

I read your post a few days ago but my son was wanting my attention and I couldn't reply. I planned to come back and write that you have to have a positive attitude about it and not get yourself stressed out by these things that are out of your control. But now it is day 10 and I just had a scan that showed only 4 or 5 of my initial 19 follicles were large enough to bother measuring, and I am feeling very stressed myself about something that is out of my control. So all my advice goes out the window as I can't even apply it to myself. Next scan is Friday which I just want to hurry up and come so it can hopefully provide me with some relief that a few of the smaller ones have caught up and I will get more than a measly 4 to 5 eggs, but I am doubtful. Probably DH's sperm won't fertilise them all, so I will be left with even less, then you know that a few die along the way to blast stage which means I will have nothing left!

I'm coming to your house to pig out on all those cakes to save your from them and so I can stuff down my sorrows after this fails. Will be bring lots of Wine too!

naty1 · 22/07/2014 10:05

Oh no!
Hopefully more will have joined in on the next scan

OP posts:
Shellster52 · 22/07/2014 23:46

Mmm... just realised next scan is Friday - day 13. That means I won't be getting instructions on when to take trigger until Friday PM which will be too late for EC on Saturday - day 14. Clinic closed on Sunday so I will have to wait til Monday - day 16. I have previous EC on day 16 last year, and estrogen dropped and progesterone rose on day 15 - both of which research shows are bad for IVF outcome. Not wanting to repeat that. Now, not only don't I have many, but they are delaying egg collection and the few that I do have are going to be overmature/poor quality. I really wonder if they just don't have many Dr's on Saturday and are delaying my EC for their convenience rather than based on what is optimal for my situation. Have left a message with nurse and am anxiously waiting for a call back to see if she will bring next scan forward to Thursday for possible trigger Thursday night and EC Sat, but she is so difficult to get along with so I am not hopeful. I also faxed a letter direct to my Dr who is more compassionate and hoping she is able to tell nurse to change things for me, but just worried the clinic is really booked on Saturday with only a few procedures being performed and nothing will be done. Sorry for the rant. Emotions are high right now. Wish they would hurry up and return my call.

naty1 · 23/07/2014 11:16

Mine seem to scan me alternate days.
I worry about the same thing... Dont think mine do ops at all on weekend. I will also be very close to aug bank holiday :(
I wonder how much it affects individuals outcomes (even if overall there is less affect.)
Its not like we choose the day period starts.

Have you looked at ivm?
It seems like its used for pcos .
It would stop the influence of when you have op etc.
The success rates are lower, but then less drugs cost

OP posts:
Shellster52 · 26/07/2014 08:39

Does IVM stand for in vitro maturation?
I am planning to ask the clinic before egg collection Monday if they have egg maturation media for eggs that are still slightly immature.
Why is it beneficial for PCOS in particular?

Well my nurse phoned back and was happier to book my scan for a day earlier (Thu) in case my follicles had grown and would be ready for EC on Sat instead of Mon. So that made me feel a lot better that they were not avoiding Sat for their benefit but rather, waiting til Mon as they thought it was best for my circumstance. And after the scan I too agree that Mon EC is best as a few are just on the small side and MIGHT catch up. From past experience, they probably won't and I only expect 3 mature eggs. But spoke to my nurse who thinks even my 10, 11 and 2 x 13mm on day 12 scan could provide a mature egg on Monday. Not sure I agree but at least it gives me a glimmer of hope to keep me sane through the weekend. Do you have any records from your previous IVF's what the smallest size follicles were that produced a mature egg?

So your clinic isn't open Sat or Sun? Here's hoping once you get your day one, it will work out that EC will be mid week so you don't have that playing on your mind. Any idea when your next IVF will be.

naty1 · 26/07/2014 14:11

Well i think i dont respond to the trigger very well (so i asked if i can have 2 so larger dose but no). They said the size my follicles some should have been mature that werent , i may have seen down to 15mm mature somewhere.
I think ivm for pcos is because there would be more eggs to collect naturally (but then you are now getting lots on baseline so i wonder if that would work)
It would be great if ivm worked i like the sound of no drugs just the operation

I start monday with pill then spray on wed. Hope my meds dont all melt in this heat

Its a difficult balance between getting lots and getting best quality

OP posts:
Shellster52 · 27/07/2014 22:26

I'm a bit lost with this IVM treatment.
I thought IVM stood for In Vitro Maturation
So I thought you took the drugs and stimmed as usual.
The lab just has the special medium to culture any immature eggs that are at Meiosis Stage 1 to see if they will mature to stage 2.
But you say there is no drugs.
What exactly is it?

Wow, so it's all happening for you Monday.
I hope I get a BFP and you are not too far behind.
Off to egg collection now
I too read that 15mm was minimum follicle size for mature egg.
Nurse thought that my 10 and 11mm follie at day 12 scan would be mature by today / day 16 egg collection.
They collected 5 eggs and 1 was immature which I assume came from 5th largest follicle at day 12 which was 13mm
So it seems logical to assume that only follies over 13mm at day 12 scan this time will contain a mature egg too... which is a measly 3
And I read that anything over 22mm is over mature.
One of the 3 follies at day 12 was already 22 then so it will be over mature now and that leaves a measly 2.
Not looking good but I am somehow desperately hoping the nurse was right and I am wrong even though history says I am right.
Leaving in 1/2 hour for egg collection
Will report back...

naty1 · 28/07/2014 09:17

Hope all went well.
As i understand it with ivm they let you do a normal natural cycle and collect the mature egg and all the immature ones and mature the others in the lab. But i could be wrong as not a lot of info around about it.

OP posts:
Shellster52 · 28/07/2014 11:33

Five eggs again today.
Feeling a bit negative about it all.
Perhaps because I had 5 in the past and failure, so this feels like the same path again.
Lady opposite me got 21 eggs which made my 5 seem pathetic effort and very infertile.
I am sure not all five will be mature as la couple of follies were on the small side at last scan.
Doing two new things this time that my last cheaper clinic didn't offer:
1 HA sperm selection to select least DNA damaged sperm
2 Calcium injection into the egg along with the sperm, to increase fertilisation rate of the few eggs I do get.
Just thought I'd mention these two things since I know you have sperm issues as well.
My nurse will phone me with fertilisation rate tomorrow.

naty1 · 28/07/2014 12:09

5 is good. Hoping they are all mature and fertilise.

I dont think mine offer the selection of best sperm - i would have liked that (esp as i had an abnormally fertilised one last time)
But it sounds like your new clinic is up on the newest technology.

Do you have to keep all meds in the fridge (its unusually hot here and most of mine say under 25•c)?
Good luck for tomorrow

OP posts:
Shellster52 · 29/07/2014 04:12

Have Crinone pessary that I just keep at room temp.
Don't know that I have to worry about it anyway as I got bad news.
Nurse just phoned and says "All 5 were mature..." (big smile) ...but only one fertilised" (my heart sinks)
So I've got one lone embryo and it seems the odds are stacked against me.
Clinic usually does day 5 transfer, but suggests day 3 with only one embryo. I have read good and bad for both and don't know what to do
Was really hoping for a day 5, but will kick myself if my embryo doesn't survive that long.
Do you have any thoughts/research as to which I should choose?
Nurse will call tomorrow (day 2) and I have to give my decision.
Or at least I hope I have to make a decision if my solo embryo hasn't already given up.