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Infertility

Our Infertility Support forum is a space to connect with others in the same position, discuss causes, treatment and IVF, and share infertility stories of hope and success.

Ivf anyone starting stimms next week?

523 replies

naty1 · 29/01/2014 21:35

Im starting stimns next week for icsi(dependent on blood test)?
Anyone at the same time want to join.

OP posts:
naty1 · 17/04/2014 13:38

Only a week till my appt now. Such a wait.
I have doubled my throxine but not sure this is enough
How are you both getting on?

OP posts:
Shellster52 · 18/04/2014 03:18

I had dr appt yest and discovered I actually ovulated this cycle which means I can start estrogen tomorrow in prep for IVF next cycle. That sounds exciting but I don't feel excited. Being a poor responder, I have less chance of success. IVF still might not go ahead if my day 2 scan doesn't show many follicles.

I got busy with studying for my nursing entrance exam and found that was at the front of my mind instead of IVF when my cycle returned to normal and I ovulated. So just going to TRY to forget it and continue studying.

So what will happen at your appointment? Will they schedule you in for another IVF? I don't know about thyroid issues but can imagine you are over paranoid about it. That seems to be your hurdle while mine is a lack of eggs.

suzylee73 · 22/04/2014 12:21

Naty, if your appt is this week does that mean your ready to go again after?
Shellster, whens your scan?

I'm looking forward to following your next IVF's :) I am hoping to go for my first consultation in Poland at the end of May so I'm a while off starting my treatment so I need live vicariously through yours haha

My consultation is 200 euros and that includes all the tests and scans! How cheap is that!

naty1 · 22/04/2014 13:03

No i dont think so as it will clash with my holiday :(
My last cycle has only been 25 days so shorter than usual (but hard to know as irregular)
Hope to get some answers though. And maybe a plan.
I think it will be a couple of months yet.
200€ is good isnt it.
Though i imagine the flight costs will add up.

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suzylee73 · 22/04/2014 14:12

Yeah the flights are about £88 each and a night in a hotel on top so it does add up not to mention the inconvenience. But I will save in the long run and I'm going for the donor egg which is still anonymous over there. I could use my own eggs but the success rate is too good to pass up, its around 65-70% with a good chance of frosties. If I were younger I would use my own but time is against me unfortunately.
I'm glad your having a holiday :) its just what you need before you start again

naty1 · 22/04/2014 18:53

I dont understand the success for donors when the stats fir my clinic say it is all the same under 35 with a 40% or so success, i guess it must be because the donors could be early twenties with nothing wrong.
It was hard enough arranging with work doing ivf in the same city.

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Shellster52 · 25/04/2014 06:59

Wow Suzy, last time I heard you were still a bit undecided. So its all happening for you now! So will you just go to Poland the once and time your arrival to coincide with your cycle so that the embryo can be transferred at the right time? I did read of one lady who did ovarian stimulation and had her own eggs fertilised as well as donor egg at the same time within the one cycle. Is that an option for you? Sorry for silly questions, I am ignorant on the whole donor egg thing as I am still desperately hoping that mine are not past their use by date. Suzy, I am currently at day 6 of my cycle and will be having a scan at day 2 of my next cycle to see if I have enough follicles to go ahead with IVF. So about a three week wait.

Nice that you are taking a holiday Nat. Just the thing you need before the IVF drama again. I wish I could afford one.

naty1 · 25/04/2014 15:17

Appt was ok.
But they didnt really want to change anything which is frustrating - as it has worked before.
I wanted to consider
Gonal f rather than menopur (pcos)
Stronger trigger shot (immature eggs)
Intra muscular progesterone (due to tummy and spotting from 12 days post collection)
Different dose

So i feel it will go badly again

We did sort my metformin , i can stay on it till next time on slow release that should stop stomach issues. Also they said it takes 3 months for eggs to grow so that should help.
My thyroxine may need further increase i need to retest in 2 weeks or so.
The only change is to let eggs grow to 20-22mm the largest , but this wont help the immature ones as this was caused by trigger
She said it was down to chance most likely so no pt changing and it wouldnt be implantation issues as i have been pg before.
I can understand but i would like some frosties so yiu want to know, if i change x i wont have all these immature ones.
They still dont want me to put back 2 really but as i understand i can insist.
On my stats 1 baby out of 4 embies does not lead me to think i would have twins
Well at least i was ahead with doing the thyroid testing ir it would have been a really long wait just on that.
I should be able to start end of june

OP posts:
Shellster52 · 26/04/2014 11:01

Must be frustrating that they didn't address your concerns - especially when you are paying big bucks for this. I know how much relief it brought me when my doctor agreed to everything I want for my next IVF.

What trigger shot did you use last time naty1 that they want to use again? Is Gonal F supposed to work better for PCOS sufferers? All my research has been based on improving response for poor responders, so I don't know much about what works for PCOS.

I did read one study that the largest follicles often contain the best eggs and that these should not be allowed to 'overgrow' to allow smaller ones to catch up. This makes perfect sense seeing as each natural cycle, your body naturally grows several eggs and chooses the best one to continue growing and ovulate.

So you have a couple of months wait now. In the meantime, there is lots you can do diet wise which research shows improves embryo quality. And a nice holiday will help pass the time!

naty1 · 26/04/2014 17:56

Yes ive been taking extra vit d and coenzyme q 10.
Gonal f doesnt have the lh hormone in which pcos makes too much of. So i would think that would be good but the consultant said as my own hormones are off it shouldnt matter.
I used ovitrelle but may have like to change to pregnyl to try to get more mature ones as it may be more effective

OP posts:
Shellster52 · 27/04/2014 00:31

I have been taking Vit D and 600mg CoQ10 daily for a while too... along with a host of others. But the main thing I am trying before next IVF is a high protein / low carb diet (when I don't cave into chocolate and chips!).
Okay, so PCOS causes you to make excess LH - makes perfect sense then to not want to use Menopur.
I agree with you on the Pregnyl too. I wanted to change to that for my IVF at my last clinic. I read that it can:
a) help mature eggs in smaller follicles and

b) stop eggs being sticky as it is natural, so less chance of not being able to collect an egg which is good for poor responders like me who don't get many to begin with
The doctor disagreed and I used Ovidrelle. But now I am waiting to do first IVF with my new clinic and I love the new doctor. She is up with latest research. And all she uses is Pregnyl!
Is there any way you can be more insistent on these matters? After all, it's your money so you should have the choice.

Barcelona123 · 04/05/2014 01:57

HELP! Does anyone have some Menopur I can buy off them today/ tomorrow? I am in Canterbury I can drive anywhere in England with cash if we can agree a price. I am undergoing fertility treatment from a clinic in Spain. They sent me a prescription which Asda got for me but today the clinic has emailed asking me to increase the dose even though I have explained you can't just pop to the chemist & buy it off the shelf especially when it's a bank holiday week-end!! Pretty desperate as have spent a fortune & will miss my window if I do not increase dosage. Please contact me if you can help a woman take her last shot at getting pregnant xx

naty1 · 04/05/2014 08:29

Shell i hope the pregnyl does the trick.
Interesting its all they use.
Where are you in treatment now?
We have decided to delay a little bit after holiday as we know we will be eating out a lot (too many chips etc) and dont want the senario we had last time of me blaming it on it being too close to xmas
But i guess it will depend on when my period falls.

OP posts:
Shellster52 · 05/05/2014 04:40

Good idea. You don't want to be faced with another failed IVF cycle and be left wondering 'was it because we didn't eat well'.

I am desparate to get IVF started but my body won't co-operate.

Normally, you ovulate day 14, then if no pregnancy, body starts preparing follicles for next cycle. So for my IVF protocol, I take estrogen from day 20 of cycle before IVF, to keep all follicles the same size and help poor responders like me get more follicles growing at same rate during IVF cycle. But my last cycle was only 19 days long. Today is day 16 and it feels like period is on it's way.

Don't know what's going on. Why are cycles going haywire.
I could swich protocol where it doesn't matter of the length of cycle prior to IVF, but I truly believe (and research shows) estrogen priming is best for my condition. Period will show up tomorrow and then I am going to track and see if my body returns to normal and I ovulate around day 14. If not, I may speak to my doctor about another protocol. I don't want to, but I can't afford to keep waiting unti while my ovaries continue to age.

naty1 · 05/05/2014 09:22

My last cycle was only 24 days which is shorter than usual.
Only a 10 day lp.
But if you have a 17 day cycle that is really short. Is that because you arent ovulating?

Im quite stressed.

I found out my sister lied to me. She is pg but they didmt do treatment at the same time like they told me all through treatment. They were already pg they are about 5 wks further along than they were saying.
Im really angry about the lying. As she is abroad they didnt need to say anything about treatment at all. Instead her DH was saying that they were 2 days behind us so they ended up doing the pg test around the same time (but werent really as they were then 3wk pg maybe)
So i 'found out they were pg' at the worst time when i found i wasnt... but that wasnt real. Also as theirs was more successful all through my treatment i heard a few days later how successful theirs was being.
And then things like telling me the numbers HCG on the blood tests werent doubling ... but really that was weeks before and they knew they hadnt lost the baby. (I could have been really worried)
But i think the worst is that when mine failed i kept believing theirs would be born on what would have been my due date which was making me more upset. (Which i said to my DM at the time). A constant reminder of something you want to forget.
They also told me in a way that made it sound like all the lying didnt matter. I mean yes if they had told me 2 weeks later maybe but this was from when i found out mine didnt work in early mar so months. Also my parents knew.
What was the pt keep lying?
I feel it is all very selfish and exactly like my DSis.
I sent them an angry message back, they tried to apologise but i dont feel like accepting it as i cant see they are sorry about it.
Its not their fault mine didnt work. But they dont have a right to be involved in my treatment while lying about their own... ie making sure they are not stressed out but not caring if they stress me out.
It is really just unfortunate we ended up doing ivf so close together.
Also they invited themselves on holiday with us so now i have to see them when im still going to be angry.
I did for a few minutes think... why am i trying so hard to give DD a sibling if is is how they treat them?
On the positive side now they are not due around that time

OP posts:
Shellster52 · 06/05/2014 07:04

I can understand if they didn't want to upset you with their pregnancy, so they thought they would wait until your cycle was finished.
But if they were trying to protect you, then they shouldn't be giving you 3 week late updates of how much more successful their cycle is, how their HCG isn't doubling etc.

Why did they lie? I don't get it.
Was it them sincerely trying to protect you?
Sounds horrible that this is now going to ruin your holiday.
I hope you can find a way to heal, so that you don't have this negativity and stress affecting your next IVF.

naty1 · 06/05/2014 09:31

I dont get it either. I think maybe her DH just was too excited about the pg and cycle he wanted to talk about it.
I think too they cant appreciate how upsetting it has been as they havent had a failed cycle (nor a sister pg supposedly due on what would be your due date).
The failing is i think a lot more upsetting than you expect beforehand. And i think that is because it is apparently chance so they were lucky and i wasnt) i think if it was directly related to say DH sperm count or my pcos that might be easier but although that is having an effect we are still getting embryos so have the chance of pg
Yep think it is not helping my jealous, why not me state of mind.
I really hope in the next few years they can perfect ivf some more. Such a high failure rate is very annoying.
We are back to trying naturally now although pointless due to sperm count, but you never know (it would be like winning the lottery) as i am still on metformin so could be ovulating. With not ovulating too before there was just no point putting the effort into timing things etc.
I have not seen anyone say they got pg with such a low count. I mean the fact we need icsi (ie never even talked about ivf and they needed to freeze some, but it only takes one.

OP posts:
Shellster52 · 09/05/2014 08:50

Sounds like a logical answer that they just didn't see things from your point of view. I get that they would be excited and tried to keep quiet until you were undergoing your IVF so that you would get pregnancies at the same time. So they were TRYING to be considerate. I think the first time you do IVF you just think it is the answer to your problems and just EXPECT it to work and they were just expecting you to both be pregnant. What are the odds that two sisters are both suffering infertility and needing IVF and doing it at exactly the same time. Does she have PCOS too?

Well I am at my wits end here. My IVF protocol runs over two cycles. The first cycle I ovulate normally, then start estrogen day 20 when the follicles are starting to grow for the next cycle. The estrogen keeps the follicles at the same size and stops the stronger ones growing so that they grow at the same rate during the next cycle - the IVF cycle.

But my day 19 blood test showed I didn't yet ovulate and that my FSH and LH were surging as though I was just about to ovulate, even though my saliva kit showed my estrogen peaked on day 13 and was not peaking day 19 in line with when my blood test says I was going to ovulate. I had cramping and bleeding mid cycle day 14. So now I am not sure when to take the estrogen as I am not sure when my body will start making follicles for the next cycle. I have just read research that confirms the daily Aspirin I am taking causes my whacky cycles.

Logically, I should wait until a normal cycle so I can take the estrogen day 20 and know I am taking it at the right stage of my cycle to give my IVF the best chance. But I can't start estrogen day 20 of next cycle as I will then need to do IVF in July when we are going on holidays! But I don't want to wait til after the holiday - it's so long away and I am not getting any younger. So I don't know what to do!

suzylee73 · 09/05/2014 10:17

Hi, just thought I would check in :)

Naty, your sister did a really stupid thing I hope you can forgive her. Maybe clear the air before your holiday.

How frustrating Shellster, you are so strong to keep doing this your amazing. I am keeping my fingers crossed that you get to start soon.

I have my appointment in Poland on the 27th May. I have to admit, using donor eggs has really taken the pressure off. I don't have to worry about egg quality and may even get frosties :) I have even looked into epigenetics and found that I would influence the genes in the womb. And I would be the biologic mother as it would be my flesh and blood, makes taking a donor egg feels more like mine in my eyes :)

A weird thing happened. DH has been really withdrawn and refusing to talk about IVF and I was really worried that he was resentful of me. Its turns out that while I was coming out of sedation after EC the doctor came and told us that his sperm has 0% chance of fertility without ICSI. I have no recollection of this doctors visit so didn't know so didn't support him afterwards at all! I felt so bad but we are ok now.

Shellster52 · 10/05/2014 23:08

So nice to hear from you suzylee. You sound like you are well adjusted to your new plan now and it must be a nice feeling to have some pressure taken off. I hadn't heard of the term epigenetics but what you say makes sense. And yes, it would be your flesh and blood. 27th May - not long now! Hope you and your hubby are getting along better - my man felt a bit de-masculated when he first got his sperm diagnosis so I imagine he would feel bad for being told he is the cause of you not having fallen pregnant naturally and having to go through all this.

naty1 · 10/05/2014 23:20

Yes interesting about the epigenetics i hadnt heard of that.
But makes a lot of sense as smoking and drinking in pg have an effect, maybe on the genes. So you can alao influence in a good way.
Silly of them to tell you/him something important right then. All i was interested in was how many eggs.

I thought you had just ivf last time and had at least 4/5 fertilise.

OP posts:
suzylee73 · 11/05/2014 09:28

We had ICSI so he must have some viable sperm and I think 8 fertilised but 5 made it over night. I haven't asked him for details so I don't know if it's morphology that's his big problem. I would never say this to him but I feel less guilty now

Shellster52 · 12/05/2014 01:27

We have known for a while that sperm is our issue (alone with my low AMH to top it off) but I can imagine how guilty (wrongly) I would feel if we weren't diagnosed with that and I felt it was my husband stuck with an infertile woman. So while I don't wish poor sperm issues upon your hubby, I am glad to hear you feeling a bit of relief in feeling less guilty.

Keep us posted with how your treatment goes! I am about to head off to my nursing appointment in prep for my next IVF.

naty1 · 13/05/2014 12:25

My tsh is now down to 1.8 which is great (needed under 2.5)
Just hope it stays there until ivf.

My sister has placenta previa so she is worried about that.
They wont confirm for a few weeks yet.
I have seen this is more common after ivf. But she has a few of the risk factors: older, more children, previous CS, etc, multiple birth - it is singleton but possibly the other implanted but stopped growing.
It sounds worrying but its possible the placenta will move.

OP posts:
Shellster52 · 13/05/2014 14:50

I had a low lying placenta at 12 weeks.
They said the gestational sac is designed to grow from the bottom
The placenta naturally moves up out of the way as the bottom of the gestational sac creates new cells and grows.
My 18 week scan revealed all was fine.
It's early days for her so hopefully she will be the same.
But you are obviously more clued in than me as I didn't realize there were risk factors for it.
So she has previous children? I was wondering about that. Must make the success of her IVF a bit more of a sting.
My sister is currently pregnant too!
But it is her first. I think if it was her second and she was able to complete her family while I can't, it would be a lot harder to deal with.

So my blood tests showed I ovulated day 19, meaning I could start the estrogen in preparation for IVF next cycle.
I am feeling the nerves in my stomach even as I type about it.
This is my 6th and all I know is failure.
I am a poor responder so I am nervously awaiting my day two scan to reveal how many little antral follicles to get a guide as to how many eggs.

So you got a follow up TSH blood test.
So happy for you that you are pleased with the result.
Must really take some of the fear out of your next IVF not working.
Can you readdress your other concerns (eg. not using Menopur) or are you just going along with what they say?
When is your next appointment?