Well, I would think a woman who claims to be a man has some issues. If she has bits of her body chopped off, that is self harm. Same with taking drugs which may damage her body. I would feel very sorry for her, of course. That she has such pain, and self loathing of her very sex.
We know that many of the girls who try to opt out of womanhood have been damaged. Whether abuse, or homophobia, and the sexualisation of female as ‘the other’. They want to escape, and think cosmetically altering their bodies will be a way out.
So, with that background, I would only have sympathy for them. I wish they could see they are fully human as the women they are. I’d be worried their loathing of themselves extends to other women as well. So, there’s that.