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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Is there a re-starters thread?

126 replies

Roadtripp · 27/03/2026 10:22

I have been off since Nov due to health issue - put on 10kg in 4 months - eating drinking like a maniac and not moving - need to restart. Do I need to work up the doses each month again or can I short circuit? Eg 2.5 for 2 weeks? If there is already a thread where all this info already please let me know

OP posts:
TimetoReStart · 07/05/2026 08:26

HappyKatieA · 06/05/2026 21:05

I’m just about to Jab my 2nd 5ml, I’ve lost about 8lbs, which I’m really pleased with. I haven’t been counting cals, just focussing on protein and fruit / veg.
much less food noise but it’s still there, I can live with that though.

That’s really good, well done. Have you increased again from 2.5 or did you go straight to 5. I’ve been doing 3.3 for a couple of weeks so might increase to 5 soon as although it really reduces the food noise, and I’ve really reduced what I’m eating, I still want to snack of an evening so maybe need to up it a bit

Clair45 · 07/05/2026 18:50

TimetoReStart · 05/05/2026 19:39

Hopefully you are feeling better now.
i think it helps me be more accountable if I share my weight and weekly weigh in

Feeling much better thanks.
Weighed in at start of this week I had a good clear out of my wardrobe over weekend and I'm between sizes so wanted to get a weight after the weekend and I'm 5lbs down (3 weeks in) so really pleased with that.

I'm getting a good level of suppression on 2.5. last time I just went up the doses. I might try this 3.?? Dose people mention rather than go straight to 5mg how do people work out the clicks etc?

HappyKatieA · 07/05/2026 19:43

@TimetoReStartI’ve worked my way up from 2.5, so have been back on it for a few weeks now. I feel so much better as I’ve taken control again.

TimetoReStart · 07/05/2026 21:31

Clair45 · 07/05/2026 18:50

Feeling much better thanks.
Weighed in at start of this week I had a good clear out of my wardrobe over weekend and I'm between sizes so wanted to get a weight after the weekend and I'm 5lbs down (3 weeks in) so really pleased with that.

I'm getting a good level of suppression on 2.5. last time I just went up the doses. I might try this 3.?? Dose people mention rather than go straight to 5mg how do people work out the clicks etc?

60 clicks is a full dose so if you have a 5 pen it would be 30 clicks for 2.5, 40 clicks for 3.33

TimetoReStart · 07/05/2026 21:33

HappyKatieA · 07/05/2026 19:43

@TimetoReStartI’ve worked my way up from 2.5, so have been back on it for a few weeks now. I feel so much better as I’ve taken control again.

Well done, I know what you mean, it does feel good to be back in control

JBJ · 07/05/2026 22:07

I restarted 2 weeks ago, after being off since January due to health issues. Did a year on MJ and lost 8st, with another couple to go. Gained 12lb since stopping! 2.5mg isn’t currently giving me much suppression at all, so I’ll be happy to finish this pen and move up
to 5mg.

TimetoReStart · 08/05/2026 01:29

JBJ · 07/05/2026 22:07

I restarted 2 weeks ago, after being off since January due to health issues. Did a year on MJ and lost 8st, with another couple to go. Gained 12lb since stopping! 2.5mg isn’t currently giving me much suppression at all, so I’ll be happy to finish this pen and move up
to 5mg.

8st is amazing well done
Its doesn't feel as strong this tome around but certainly helps curb my appetite. I'll be happy losing 1-2 lbs a week to get rid of this last stone

CherryViper · 12/05/2026 14:24

Restarting MJ tonight.

Taken my measurements and weighed myself ready.

HappyKatieA · 12/05/2026 20:16

Good luck @CherryViper

TimetoReStart · 12/05/2026 22:23

CherryViper · 12/05/2026 14:24

Restarting MJ tonight.

Taken my measurements and weighed myself ready.

Good luck

CherryViper · 14/05/2026 13:12

So far, so good.

As per last time, I don't feel full up or unable to eat. Food noise is reduced.

I am feeling cold. Weather has turned

justsaxy · 18/05/2026 19:44

So I am struggling, the suppression doesn’t seem to be as strong as I remembered it.

weighed in at 96k today. GW of 70.

Clair45 · 18/05/2026 19:51

What dose you at currently?
I'm on week 4 ,of 2.5 and definitely need to move up as I'm not getting longer than about 3 days. Ive got my 5mg pen but I'm going to do 45 clicks and give myself I think it's 3.35mg rather than moving straight up to 5.
I'm 6 lbs down this month but I've also really ramped up my exercise too. Something I didnt do last time round.

CherryViper · 18/05/2026 21:25

I'm on 2.5mg. My suppression has never been the overwhelming fullness and inability to eat that other people report.

I never had a big weekly loss. My inflammation is much improved.

I am interested in halfway dosing by clicks. I'll check in to see how you get on. X

Clair45 · 19/05/2026 18:27

Fingers crossed the suppression improves for you, or you might see an improvement when you go up next.
You could try like I am and don't go for a full 5mg and see if you get suppression on fewer clicks if not then give yourself the full dose the week after.

CherryViper · 19/05/2026 22:39

I have been tracking calories and will have my first weigh in tomorrow.

I have seen about doing clicks and taking 3.75 mg rather than 5mg. Thanks for the suggestion.

Like you I know I need to exercise way more. My joints are still painful.

TimetoReStart · 20/05/2026 09:06

Well that was an interesting weigh in, after being away for a few days last week, I was really pleased to be in the 9s, weighed at 9.11.2 first thing, woohoo, went downstairs had a cup of coffee, double checked the scales, 9.12.2, I’m giving up coffee 😂😂

CherryViper · 20/05/2026 21:26

First week weight in, lost 1.8lbs. bit disappointed in that. I was expecting to lose more from the first week.

Second injection tonight. I usually go for stomach, might try thigh.

TimetoReStart · 24/05/2026 13:44

CherryViper · 20/05/2026 21:26

First week weight in, lost 1.8lbs. bit disappointed in that. I was expecting to lose more from the first week.

Second injection tonight. I usually go for stomach, might try thigh.

Keep going, I didn't get the big loss this time around but it is still working

HerFifthDecade · 24/05/2026 16:25

👋🏻 May I join? I’m starting MJ again tomorrow.Managed to loose 3 stone last year but had to stop with price rises which was a shame as only had 8lb to go for goal!
I’m currently 12.11 and want to reach 11st ( got to 11.8 Xmas week) .onwards and upwards 👍🏻

Zazu44 · 25/05/2026 04:47

May I join too. Restarted MJ Friday on 2.5 after losing lots last year.
I stopped MJ before as I got a huge reaction on the injection site - itchy angry red welt ( any tips for this greatly received). Tried Wegovy for a bit no reaction but not as good, stopped and have put 8lbs back on in a short time.
Food noises were definitely back massively so I bit the bullet and bought some. Haven’t noticed any difference yet and have had usual red welt 😫.
Hope 2nd dose will be better. 🤞🏻🤞🏻

Vivienne1000 · 25/05/2026 04:55

Roadtripp · 27/03/2026 10:22

I have been off since Nov due to health issue - put on 10kg in 4 months - eating drinking like a maniac and not moving - need to restart. Do I need to work up the doses each month again or can I short circuit? Eg 2.5 for 2 weeks? If there is already a thread where all this info already please let me know

If you have been off work for over 6 months and are not well, make sure you are OK to take mounjaro. Maybe seeK medical advice.

SerenitySeeker4 · 25/05/2026 05:20

Honestly I’d ease back in properly rather than trying to shortcut it — especially after a few months off. Most people restart from the lower dose again to avoid the nasty side effects, even if they tolerated higher doses before. You could probably do 2.5 for a couple of weeks then move up if you’re feeling okay, but I’d definitely check the guidance for your specific medication or ask your prescriber/pharmacist. And don’t beat yourself up over the 10kg, months off sick can completely throw everything out of sync. The important bit is you’re ready to restart now.

TimetoReStart · 25/05/2026 09:43

Zazu44 · 25/05/2026 04:47

May I join too. Restarted MJ Friday on 2.5 after losing lots last year.
I stopped MJ before as I got a huge reaction on the injection site - itchy angry red welt ( any tips for this greatly received). Tried Wegovy for a bit no reaction but not as good, stopped and have put 8lbs back on in a short time.
Food noises were definitely back massively so I bit the bullet and bought some. Haven’t noticed any difference yet and have had usual red welt 😫.
Hope 2nd dose will be better. 🤞🏻🤞🏻

Welcome Zazu44 can’t really help with injection site reaction, where about are you injecting? It took me a few increases to reach proper suppression again, currently on 25clicks from a 10mg pen, so I think that’s about 4ish mg which is working well although weightloss is slower I think it is nearer the rate it was before I stopped last time, which makes sense really,

Clair45 · 25/05/2026 10:21

Welcome newbies
Week 6 and I'm 6lbs down much slower than last time but it's coming off.
I've used 42 clicks of 5mg pen this time round rather than going straight up to try and help save money. Wow I had worse headache all weekend. Could be the sun as I've not drank enough and I get migraines with sun. So need to watch my water.

How's everyone else getting on?

Zazu - Injection site problems try giving somewhere else, or take out the fridge before hand. I saw someone else mentioned this on a other thread.