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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro - 10 Stone or more to lose - Thread 13

990 replies

TheBroonOneAndTheWhiteOne · 22/03/2026 18:22

Let No.13 be lucky for all of us.

Good luck, losers.

All welcome!

OP posts:
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41
TheBroonOneAndTheWhiteOne · 23/03/2026 17:50

@eibbed999

I'm so sorry. I could feel the desperate sadness and despair in your post.

Are you ND? ADHD meds generally help with impulsivity and provide a dopamine hit.

If you haven't been diagnosed but think you fit the criteria, ask for a referral.

To get a GP appt sounds very difficult for you, but it must be possible somehow.

I may be barking up the wrong tree, but you describe such out-of-control behaviour that neurodiversity must be a possibility.

Yes, I know that getting a diagnosis and then treatment would take ages, but if it would ultimately help, it would be worth it.

Two more suggestions:

  1. stop the MJ for eight weeks. Yes, you'll gain a lot in that time, but you're gaining anyway at the moment.
    Then restart it at 2.5mg and try to stay on the lowest possible effective dose for as long as you can.
    You may find that your body has a reset if you do this.

  2. my other suggestion completely ignores the MJ prescribing guidelines - inject 20mg every six days. I've heard of doctors who have prescribed 20mg MJ (off-label).

If this causes diarrhoea, take loperamide.

I hope you can find a way to get that six stone off. And I'm terribly sorry that you're mentally suffering so much.

You're not on any other medication that causes weight gain, are you?

OP posts:
TheBroonOneAndTheWhiteOne · 23/03/2026 17:55

I don't know why that last post appeared twice.

OP posts:
PearlsTeapot · 23/03/2026 18:19

Broon gives good advice.

@eibbed999 I've been thinking about you today. I would go for a full break (4 weeks to get it out of your system) then starting again at 2.5. Do that now with those 2 pens you've got and just count clicks with them. Then if that doesn't get things moving again go to wegovy.

TragicMuse · 23/03/2026 18:23

Oh @eibbed999 I’m so sorry. I don’t have anything wise to say but I can hear all your pain and fear and how utterly killing it is for you.

eibbed999 · 23/03/2026 18:31

Thank you again, you sweet kind souls. This is possibly the only group of people who would understand. I may well take a month off as suggested - accept the hit, and start all over again. As you've pointed out, I'm already gaining.

No, I'm not ND at all - I think it's more addiction issues. If it wasn't this it'd probably be something else. I have friends who are autistic and/or ADHD and I'm genuinely not. Certainly with ADHD, I've seen the difference that the meds have made to them. I'm not on any other medications, and I'm gaining because I'm eating like a twat - there's no mystery about it. Sadly controlling my inner twat seems to be impossible at the moment. It always has been, apart from those first few months on MJ, where the world felt made of sunshine and rainbows!

I jabbed today. Will see how I do this week. But you know that feeling, when you're going to start a diet - like, I don't know, after Christmas or whatever? Where you know you are going to start dieting so you basically try and eat your own body weight in crap in the days running up to it? I kind of have that sensation all the time!

Missingducks · 23/03/2026 18:41

@eibbed999 my inner twat sees and recognises your inner twat ... Mine knows there is a packet of mini eggs in the cupboard left over from prizes at an event yesterday. I could ask my husband to eat them (which he would do with delight) but my inner twat won't let them be eaten without sharing. Even though we are not eating chocolate. And it's not yet Easter. But those sodding eggs are calling and my inner twat says 'well if we eat them we won't be able to hear them anymore'.

RenegadeKeeblerElf · 23/03/2026 18:52

Missingducks · 23/03/2026 18:41

@eibbed999 my inner twat sees and recognises your inner twat ... Mine knows there is a packet of mini eggs in the cupboard left over from prizes at an event yesterday. I could ask my husband to eat them (which he would do with delight) but my inner twat won't let them be eaten without sharing. Even though we are not eating chocolate. And it's not yet Easter. But those sodding eggs are calling and my inner twat says 'well if we eat them we won't be able to hear them anymore'.

Give them to the foodbank? I know for me that's the only way I'd be able to stop that little voice

TheBroonOneAndTheWhiteOne · 23/03/2026 18:54

RenegadeKeeblerElf · 23/03/2026 18:52

Give them to the foodbank? I know for me that's the only way I'd be able to stop that little voice

I'd eat them on the way to the food bank.
🤣

OP posts:
Doggymummar · 23/03/2026 19:25

@eibbed999 so sorry to hear your struggles, it must be so difficult to feel so out of control.

I just checked back and today is my three year anniversary on weight loss drugs!

I must have spent about £8k but would do it all again in a heartbeat. Started at 254 lb and have lost 96.2lb so far. I did lose 48lb on my own before starting meds so 302 was the actual start weight.

By Christmas 2023 I was 195.6 but so ill from throwing up daily I had to give up, this was Ryselbus.

I tried to lose on my own, but actually gained half a stone and started MJ in September 24 at 202lb.

By Christmas 2024 I was 192lb, the MJ didn't work until I got to 10mg so that was hard

Been on 15mg since Jan 25, by Christmas 25 I was 156lb and today 157.8lb.

I have the golden dose of my last pen for next week then switching to 2.4 Wegovy. I genuinely know I will have to take something for life and some of you might think I have wasted my money. I hope not tho.

I am 56, unemployed and I am actually proud of myself for not giving up.

There are so many of us nearing 7 stone on mj. I'm proud of all of you, for digging in and getting on with it.

PearlsTeapot · 23/03/2026 19:33

96lb is life changing, nobody here will think you’ve wasted money @Doggymummar you’ve changed your life and your health. Have you jabbed today?

Iwouldratherbesinging · 23/03/2026 19:43

Oh @eibbed999 sending you hugs 🫂
You’ve shown why this space matters so much and you’ve put into words something that a lot of people probably recognise, you certainly haven’t failed, you have lost four stone! You did that, you worked at it and your body responded. That’s a huge achievement and none of that disappears because things feel so hard right now.

Your post is heartbreaking to read because you’re right, it’s like being shown a completely different way of life and then having it taken away and you’re grieving that, that’s not a weakness, that’s a human reaction. No one here will judge you, you’ve been so brave by saying it all out loud.

It suggests to me that something has shifted physically especially as it worked so strongly before, but not that no one can help you. Can you speak to your prescriber just to look at whether something has changed? I can see why the idea of a break sounds terrifying but that feels like something you shouldn’t have to figure out alone and in all honesty this doesn't sound like a will power issue at all. A suggestion that was made to me a long time ago around binge eating was to try and delay it by 20 minutes just to try and take some ‘power’ back.

But… You’ve done so well, even if it doesn’t feel like it right now. Your must keep posting on here, just being so honest is a really big step
sending you a massive hug ❤️

TheZingyFish · 23/03/2026 19:58

@eibbed999 Try to stay strong and just go the advice given here. I’d come off it completely and just accept and be at peace that you will gain some and start up again when you feel strong enough. You’ve done so amazingly well to come this far, just try to accept that we all have blips, even slim people who don’t struggle with weight will put some weight on at times, but this needs to be a mindset change.

At the moment you’re struggling with eating and so are putting weight on which you can’t control, but you can control how you react. I think if you stop being so hard on yourself you’ll find it easier to get out of your rut. If you’re eating things which you’d previously been avoiding when losing perhaps enjoy them a little and don’t feel so guilty, that will take the shame and guilt away so you won’t feel bad. If you’re feeling more positive you’ll be more likely to make a different choice next time with what you choose or how much you choose.

So many of us have poor relationships with food from our histories but try not to let this blip impact yours. We’re all here with you, every step of the way.

Doggymummar · 23/03/2026 20:02

PearlsTeapot · 23/03/2026 19:33

96lb is life changing, nobody here will think you’ve wasted money @Doggymummar you’ve changed your life and your health. Have you jabbed today?

I did ! Thank you

Theringcycle · 23/03/2026 22:24

I have eaten what feels like comparatively a lot today (compared to usually) without feeling full at any point. I think my period is due in a couple of days. Does anyone find that this affects the suppression of their medication? This would be my 2nd cycle since starting but the first one was only a week or so in.

Motnight · 23/03/2026 22:37

@TheBroonOneAndTheWhiteOne thank you for starting this thread. I was quite quiet on the last one, lots of work stress currently so just concentrating on getting through it really

@eibbed999 really sorry to read your posts. I get it. I hope that your reset works.

Haven't lost more than a lb over the last month. Mostly because at heart I am a greedy food addict still. Not sure that will ever go. But want to lose another stone by the end of July. Have lost about 115 lbs.

MCR24 · 23/03/2026 23:00

My inner twat bought an Easter egg today. I don't really need it but I'll enjoy it when I eat it.

SilenceInside · 23/03/2026 23:28

Thanks for the new thread.

I am not really losing any weight at the moment, I am just bouncing around the 70kg mark, and don’t seem to have the will to drop securely into the 60kg bracket. I think I’m suffering from a bit of mental fatigue about the whole process. I am contemplating a lot about how to get back on it, and how to summon up the mental energy to focus on it all again. Started off this week ok, so my current plan is to sustain that for the rest of the week and see if I can get a loss even if it’s small.

Doggymummar · 24/03/2026 06:56

SilenceInside · 23/03/2026 23:28

Thanks for the new thread.

I am not really losing any weight at the moment, I am just bouncing around the 70kg mark, and don’t seem to have the will to drop securely into the 60kg bracket. I think I’m suffering from a bit of mental fatigue about the whole process. I am contemplating a lot about how to get back on it, and how to summon up the mental energy to focus on it all again. Started off this week ok, so my current plan is to sustain that for the rest of the week and see if I can get a loss even if it’s small.

Seems a lot of us are at the same stage, it's mentally and emotionally tiring to have stuck at this for so long. And expensive. I just have to think of it one meal at a time now.

MellowShirly · 24/03/2026 07:33

Hi, I could do with some help. At the begnning of Feb, I was 23 stone, 3 pounds. I'’m now 20 stone, 9 pounds. I've done it through low carb and 16:8 timed eating. But I'm having a hard time. I'm 47, menopaused. Should I get some injections? Food noise there all day. I don't do any exercice.

Motnight · 24/03/2026 07:40

Wow @MellowShirly you have lost a lot of weight in a very short time. Even with WLI, it's blooming hard for most of us. Honestly if I were you I'd carry on doing what you are doing (though I am not sure that losing so much weight so quickly is either sustainable or healthy) as it's working for you. Is there any reason why you don't exercise?

Motnight · 24/03/2026 07:45

@eibbed999 I think that @TheZingyFish has written a really useful post about mindset. I remember someone writing that a normal sized person might put on half a stone at Xmas time. But they don't see it as the beginning of a downward spiral, just as a fact that they need to address. It's very hard. My moods can be dictated by whether the scales show a loss or gain. Completely unhealthy, I know that.

Tereseta · 24/03/2026 07:56

I've started in February this year and am week 2 into 7.5mg. So far I have lost about 1 stone but it is slow going. What is everyone eating?

eibbed999 · 24/03/2026 07:59

Thanks yet again, all of you - so many really lovely responses to my meltdown. Lots of food for thought, suggestions and fresh perspectives. Mainly just bucket loads of kindness and support, which has made me feel so much better - I don't know why I stayed away for so long struggling on my own, all part of the mindset I suppose - like not weighing when you know the news is going to be bad, and ignoring the bad patterns that are building.

I wish those of you also struggling the best of luck, I wish those of you getting there my total admiration and congratulations. And I wish those of us wrestling with our inner twats huge amounts of strength!

SilenceInside · 24/03/2026 08:12

@MellowShirly You have done amazingly, that's a huge loss in a short space of time.

The injections are brilliant at helping you stick to a calorie deficit, whatever way you manage that, over a long period of time which is what those of us who start at high weights need. It helps to stop the "diet fatigue" and the risk of going off programme and then having a rebound regain. If they work well for you, they are likely to reduce or remove the food noise.

But, they are expensive and you would be committing to taking them long term, and possibly indefinitely/very long term. Plus the risk of side effects, but I think for those of us who are in the 10st or more to lose category, the risk/benefit analysis is quite straightforward as the risks of remaining morbidly obese are much higher than the risks of side effects from WLI.

MrTiddlesTheCat · 24/03/2026 09:11

@MotnightI'm the same. It's scary how much power the number on the scales has over my mood. I want to break free from that.