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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2026 starters

539 replies

Behealthy2026 · 01/03/2026 13:48

hi, I thought I would start a new group. I am waiting for my medical review before being issued with my first dose

OP posts:
Seriestwo · 18/04/2026 22:20

Do people do the golden dose? I got 0.75ml which is more than 2.5mg. I’ve been on 2.5 for 6 weeks or so and it’s working but I have 2 more 2.5 pens. I didn’t want to waste it!

MoneyJo · 18/04/2026 23:46

I did get the extra dose from my first pen so 5 weeks worth. I think I'll get it from this current pen too but I don't expect to get it from any future pens.

Asgoodas · 19/04/2026 13:48

My first month was brilliant - 15lbs down!
The second month ( I’m about to take 7th jab) has been very different. We have a good social life and for the most part I have been good, but attended a wedding weekend last weekend. I made the decision to enjoy it and drink and food was consumed. The next weigh in was a six pound gain 😳 This week has been about damage control and getting back in the game. These events will happen and I need to be able to adjust. I can’t afford to keep the jabs up- financing this is short term only.
I’ve ordered the same dose for my third month even though the repression is not what it was. My thinking is that I need to be able to cope with hunger and food noise by rethinking my diet and movement. MJ has given me the space to reevaluate my lifestyle and, even though it’s not as effective, my weight loss will only succeed if I’m committed to the changes I have made.
so this week has been hard. After a gain like 6 pounds, I was so pissed off. I have to allow for social times- I love being out with friends and having drinks and meals 😋
I got back to the food choices and made an effort with exercise and weighed myself this morning. I’m back to pre wedding weight 🎉 I lost 6lbs exactly🎉 it’s so liberating to know if I fuck up, it is possible to claw it back.
I can afford three more pens, then I’m on my own. I don’t want to up the dose, so will remain of the starter dose until I finish.
Am I being too naive?

Seriestwo · 19/04/2026 18:10

i get a gain after drinking and carbs and fun, chat tells me it’s to do with water retention. You’d have to eat a lot o actually gain 6lb. Good luck

Seriestwo · 20/04/2026 00:00

If I lose a pound a week I will be a comfortable size 14 by Christmas. This seems like an impossible dream. Less impossible than usual though.

ShebaQueen · 20/04/2026 08:02

7 weeks done now and into the last week of my second 2.5 pen. I'm down 8kg overall which I am really pleased with. Definitely finding my appetite is creeping back though, so am battling that with set meal times and distraction techniques. I have my 3rd pen in the fridge - going up to 5 next weekend and slightly nervous about the possible return of the side effects.
How is everyone else doing?

Engineeredit · 20/04/2026 08:45

Could someone explain exactly how to administer the first dose? I have watched a video several times and still find it very daunting. Don't want to do it wrong.

MoneyJo · 20/04/2026 08:50

@Engineeredit I found the leaflet in the box much easier to follow. The steps are very clear and simple.

MoneyJo · 20/04/2026 08:50

Finally down another pound today after stalling for a week. That takes me to exactly one stone down since first jab on 5th March. Not speedy but I'm fine with that.

Darkspiderplant · 20/04/2026 09:13

That’s amazing @MoneyJo, well done!

I am so depressed about my weight loss. I have had a few days of not counting calories, but still sticking to the same food I’ve been eating recently, and today, I weighed more than I did last week! I’ve only lost 1kg since I started 3.5 weeks ago 😢 I’ve got a wedding on Friday, I was hoping I would have lost half a stone by now and would be feeling better about myself. I feel like I’ve wasted my money on MJ now. This week and last week I’ve hardly felt like I’ve had any suppression and I’ve been craving chocolate a lot.

MoneyJo · 20/04/2026 09:36

It sounds to me like you need to get up to 5mg @Darkspiderplant I think a lot of people don't lose on 2.5 as it's just a dose to get you used to it.

Beehivebabe · 20/04/2026 10:02

@Darkspiderplant. I agree with @MoneyJo that for a lot of people 2.5 is just getting it in your system and you likely need a bigger dose. I am sticking to 2 meals a day plus fruit which seems to suit my weight loss and has worked for me in the past, as it’s like a form of fasting I guess. Also cutting out most bread and sticking to wraps or just salad and protein. I’ve lost 25lbs now but I started at 19st 13 so I would expect a bigger loss at this point. I’m under no illusion it will get harder!

CottageGate · 20/04/2026 10:07

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ShebaQueen · 20/04/2026 12:02

25lbs is incredible @Beehivebabe, well done!
Hang on in there @Darkspiderplant, everyone is different and I think @MoneyJo is right, you may need a higher dose.

Darkspiderplant · 20/04/2026 20:27

Yes, hopefully I’ll shift more when I move onto 5mg. I can’t decide whether to try and get the 5th dose out of my 2.5mg pen or to go straight onto the 5mg pen.

Seriestwo · 21/04/2026 10:47

I think the dose lasts a while in the fridge. Keep it for if the 5mg wears off? As a stepping stone?

Seriestwo · 21/04/2026 10:47

I had an itch, gave it a little scratch. And found a collar bone! Haven’t felt that in a while.

taratill · 21/04/2026 12:56

Just back from a week in an AI resort and I've gained a couple of pounds. To be expected I suppose! Back on it this morning with more sensible food choices.

Well done to all of those losing weight.

I have just ordered the 5mg pen. I'm not 100% sure what to do. I still have 2 doses of 2.5 on current pen and will see how that goes as I'm not bothered about fast lost as I think slow and steady is better for me health wise, so I may just do 30 clicks if I'm still on a downwards trajectory after the next 2 doses.

taratill · 21/04/2026 12:57

Seriestwo · 21/04/2026 10:47

I had an itch, gave it a little scratch. And found a collar bone! Haven’t felt that in a while.

That's brilliant! Love it.

MoneyJo · 21/04/2026 15:36

Just back from a week in an AI resort and I've gained a couple of pounds
It took me a moment to realise that you didn't go to a Co-Polit resort!

Snoringdogsfarting · 21/04/2026 16:19

Been following but my first comment on this thread . I had 5 weeks of 2.5 including the “golden dose” and lost 18lbs but that was hard work as still felt hungry ish. Anyway I decided for my 6th jab to go up but luckily not all the way to 5, I counted clicks and did 45 and feel so bloody ill 😭I have forced myself to eat 1/4 of a slice of whole meal toast but the idea of anything else 🤮 I can’t drink a whole cup of coffee and even the smell of water makes me nauseous. I won’t be doing this again, that’s for sure! 2.5 straight to 5 seemed crazy to me and I’m so glad I didn’t do it as 3.75 has made me feel so poorly 🥺 I’m not wasting all the money I’ve spent on this 5mg pen but I’ll definitely cut back clicks to 2.5

MoneyJo · 21/04/2026 18:18

Wow @Snoringdogsfarting that's awful.. it seems like 2.5 was working for you though - that's a lot of weight to lose in a short time.

@taratill sorry, I meant Copilot not Co-Polit!

I seem to have lost two pounds in two days but that just goes to show the ups and downs of it all - I hadn't lost anything for the week before.

Snoringdogsfarting · 21/04/2026 18:55

MoneyJo · 21/04/2026 18:18

Wow @Snoringdogsfarting that's awful.. it seems like 2.5 was working for you though - that's a lot of weight to lose in a short time.

@taratill sorry, I meant Copilot not Co-Polit!

I seem to have lost two pounds in two days but that just goes to show the ups and downs of it all - I hadn't lost anything for the week before.

It was hard work to lose as I was still hungry and had to be very very firm with myself which is why I went up a bit on the dose. I’ve got about another 20lbs at least I’d like to lose - I’d still be large but dont want the saggy face that happens . I’m old but do not want to look like Sharon Osbourne 😲

Teabing · 23/04/2026 15:20

Afternoon all. Having done 5 lots of 2.5mg I was hesitant to go up straight up to 5 so settled on 3.75mg last week. The past week has been ok - suppression wore off around Tuesday so I’ve gone to the full 5 today. Feels like a momentous event. Got a relatively quiet weekend so will be able to cope with unwelcome side effects should they arise.

How’s everyone getting on?

MoneyJo · 23/04/2026 15:25

I had the same experience as you @Teabing except I had one whole week on 3.75 and then my second week of it just felt different. Someone in these threads advised making it up to 5mg half way through the week so I did that and it was great. Jab day for me so just deciding whether to do another week of split or just go for 5 straight away.