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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2026 starters

539 replies

Behealthy2026 · 01/03/2026 13:48

hi, I thought I would start a new group. I am waiting for my medical review before being issued with my first dose

OP posts:
HolyMoly24 · 14/04/2026 09:24

Hi all haven’t checked in for a couple of weeks as nothing much to report. I’m 19.5 lbs down now since the beginning of March. So happy!

I haven’t needed to throw any trousers out yet but it has been a massive eye opener as to how much I was squeezing myself into size 16 jeans. I definitely should have been buying an 18 but was in denial.

My barrel leg jeans are now zipping up easily and fitting how they should instead of being very fitted down to the knee…

taratill · 14/04/2026 09:32

Well done @HolyMoly24 !

I decided to jab today, so back to the original day. Got everything crossed that I don’t get side effects, although theoretically I am now just back on schedule so hopefully fine.

At the moment I don’t see any need to go up to 5, as I’m losing steadily, but I might order the 5 pen and use it for longer by just clicking 2.5 next month as there is only £10 difference in price.

Beehivebabe · 14/04/2026 16:50

@HolyMoly24. Well done! I think I was also squeezing into smaller clothes haha, don’t we all!

@taratillI ordered a 5 this week as I do think suppression and food capacity has slacked a bit. One more 2.5 jab to do first. I’m sure you will be fine if you haven’t experienced too many side effects anyway.

Darkspiderplant · 15/04/2026 08:38

Well done yo everyone who has lost weight!

I’ll be honest, my progress feels pretty slow. I’ve lost 3lb so far and I’m taking my 4th injection today. It’s not a huge amount, but it’s still progress, so I’m trying to stay positive. My next pen has arrived as well. I’ve moved up to the 5mg one.

I’ve been tracking my calories closely, and I’ve noticed that if I stick to around 1300 a day, I do lose weight. I had a few days at 1600 and ended up gaining 1lb, which was frustrating. It really puts into perspective how easy it was for me to gain weight before.

Slow and steady, I guess, focusing on consistency.

I am still hungry and cravings have not gone away.

SmallTreeDeepRoots · 15/04/2026 10:40

@Darkspiderplant Sounds like you know what you’re doing! Fingers crossed the next pen makes the plan easier for you to stick to.

Darkspiderplant · 15/04/2026 11:24

I am wondering how I will ever keep the weight off. I can’t see me sticking to 1500 ish calories a day for the rest of my life. It’s so low.
A typical day for me is
Porridge for breakfast - 350 cals
Sandwich with filling for lunch - 350 cals
Veg stir fry with protein for dinner - 600 cals

This gives me about 60g of protein a day.
That’s it. No room for snacks or anything. Even on MJ, I’m still hungry eating like this.

taratill · 15/04/2026 11:44

@Beehivebabe

I can report back no symptoms (other than a small red rash at the injection site that I get each time).

I'm going to order 5 next time and see how it goes. I'm definitely still losing on 2.5 so I may just make the pen last but will have options if I find I stall.

@Darkspiderplant I know what you mean, it's tricky isn't it. My downfall is a glass of wine/ beer not snacks & unfortunately I haven't experienced going off it like a lot of people do.

SmallTreeDeepRoots · 15/04/2026 12:41

@Darkspiderplant I haven’t worked out my calories yet. A lot to lose and it’s coming I’ll steadily atm. But I too have qualms about long term. As I approach a healthy weight, my baseline calorie requirements will also reduce as I no longer use so much energy lugging my carcass around. Vague plan is to build muscle and continue exercising. Also a lot of crossed fingers. But I’m trying to worry when/if I get there! Maybe I will be on the jabs for life.

Seriestwo · 15/04/2026 12:47

@taratill also not put off alcohol and I’d say it she only thing I really have “noise” about. I have been drinking tonic and ice in a nice glass, trying to trick myself into thinking it’s like gin. Which works but my choice be wine.

I will stay in the drug for life. I have no condense that I can control my eating. If microdosing reduces my weight then what we risks about long term use are found in willing to risk them. Being this fat will kill me.

ETPhoneHome19 · 16/04/2026 07:54

Weighed in this morning and I’ve now lost 6.6kg (14.5 lbs!) since I started 6 weeks ago.
Clothes are fitting a lot better now which is good, size 16 trousers are feeling a bit big and I can get into my 14s again.
The only side effect I’m having is acid reflux when I’ve had a couple of drinks, I’m not drinking as much as I normally would but having a few socially and adding the calories into my diary

Seriestwo · 16/04/2026 09:02

That’s over a stone! Good for you

taratill · 16/04/2026 09:45

Well done @ETPhoneHome19! Amazing loss!

Acid reflux is an interesting one for me as I used to get it really badly but haven't been since I've taken the injection until the last couple of days when I've eaten richer foods because I've been eating out. Glad to keep a stash of gaviscon sachets in my handbag!

And what a lovely feeling when clothes feel loose!

Darkspiderplant · 16/04/2026 10:01

Well done @ETPhoneHome19! that’s amazing.

I took my 4th injection today. There’s still loads left in the pen. Can I get it out by forcing the barrel round? I managed that when I was on MJ before but have the pens changed to make that harder to do?

I officially weighed in today and I’ve lost 3.5lb since I started at the end of March. I was hoping for more than that. I was hoping to
lose at least half a stone from my first pen. I need my chocolate and wine cravings to disappear!

Behealthy2026 · 16/04/2026 10:05

@ETPhoneHome19 Great work!

@Darkspiderplant yes I have a little bit over in my first pen. I would love it know. I tried to move it but it didn't budge that much! Haha

back from knee surgery, and 2 weeks off. I haven't weighted mainly because I'm worried about the number and it was over Easter.

i also had the second pen in the fridge for 2 weeks and hoping that it's ok to use it. Actually I might ask the supplier.

OP posts:
taratill · 16/04/2026 10:16

@Behealthy2026 I think the Pen is good in the fridge till expiry date if unused. Unless I've misunderstood what you mean?

Rawrrawr1 · 16/04/2026 10:25

I just needed to add this somewhere as apart from DH no one else knows I'm taking MJ. Took my first dose of 5mg today after a month on 2.5 and I have lost 11lbs and some inches but will need to get my spreadsheet out to calculate that.. I am so very very chuffed.
I have a lot (approx 10stone) to lose so this is just the start for me

Teabing · 16/04/2026 10:47

@Darkspiderplant You can apply a bit more pressure to move the barrel to use the golden dose. Marigolds are helpful if more grip is required. I managed to use my last bit last week.

MoneyJo · 16/04/2026 13:04

@Darkspiderplant I made it work with a pair of pliers and twisted the pen back to zero. Then I could get a whole extra dose out.

Darkspiderplant · 16/04/2026 14:43

Thanks, hopefully I will get an extra dose out of the pen.

Has anyone told people that you’re on the jabs? I haven’t. I’m debating whether to be honest or not. My weight has yo-yo’d so much over the years, I got very thin about 10 years ago then put on weight in covid and lost it again then put it on again so most people I know have seen me at all sizes so I can say I’ve done what I did before if I decide not to tell people about the jabs.

MoneyJo · 16/04/2026 14:46

My immediate family know, and my best friend and two other friends who told me they were on the jabs. That's it. I'll wait and see how it goes.

Beehivebabe · 16/04/2026 15:48

Well done all on great losses!

@Darkspiderplant only my husband and two daughters know. They are all so supportive and I don’t know why I’m hesitating to tell anyone else! I wonder if they think I am cheating at dieting or something. It’s silly as I would never judge anyone.
@Rawrrawr1 let us know how you get on with going to 5. I have done 2 pens of 2.5 and my next pen will be 5, I was going to click to 3.75 then thought I may as well go straight to 5 and have done with it.

ShebaQueen · 16/04/2026 17:09

I've been open about being on Mounjaro. I expected some comments about it being a cheat, warnings about side effects, doom and gloom about putting it all back on again etc. but so far, everyone has been supportive. Several of my friends have been using it for a while, so that helps.

SmallTreeDeepRoots · 16/04/2026 17:27

7 jabs in and still losing about 1kg a week.

SW 5/3 115.4
CW 16/4 106.6
1st target 111.5 - BMI under 40 26/3!
2nd target 105 - weight at 40yo

BMI has just sneaked in to 37. Got measured for a new sports bra today - old one had stopped doing the job. The back size is the same but cup size has gone from HH to F. I also bought size 18 jeans! A normal shop size! (OK it was M&S so generous sizing, but still a mainstream size not a special fat shop size!)

I’ve ordered a third pen at 2.5 - decided not to increase the dose which the lower one is steadily doing the job at a healthy rate.

ShebaQueen · 16/04/2026 17:34

That is fab @SmallTreeDeepRoots! I'm sticking on 2.5 for pen 3 too

nickdrakeslovechild · 16/04/2026 19:04

Hi, can I join please! Started MJ 2.5 on 23rd March. 5ft 1 and was 13.13 which is the biggest I have ever been and really unhappy about it. I have had a binge eating disorder most of my life and this is the first time EVER that the food noise has been turned off. I actually had a cry about it as it's such a freeing feeling.

No negative SE but the first week I could only eat a mouthful of yoghurt and berries and ended up losing 9lbs. I will do my 5th dose on Saturday and sticking with 2.5 but going up to 5 when I reorder in 2 weeks as definitely hungrier this last 2 weeks. (but still able to choose healthy options which is truly amazing)

Weighed in today at 12.11 so fingers crossed I'm aiming at 12.10 on Sunday!