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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

February 2026 starters

969 replies

Crossfitgirl · 30/01/2026 12:00

Hi all, I have my first pen on the way and as far as I can see there is no starter thread for Feb, so I hope it's ok to make one.
All welcome whether recently started or looking to start this month - I think by the time mine arrives it will probably be February!
Hoping for support, experiences, recommendations, more support and the rest!

I am nearly 40, 2 young kids and full time job, starting on wegovy, with the goal of lowering my cholesterol (and reducing my huge belly).

OP posts:
Thread gallery
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Beekman · 12/02/2026 16:15

Day 5 on the Wegovy tablets and I still cannot believe I am having to remind myself to eat. Long may it continue! (But not the sluggish bowels, my only side effect so far)

wlinewbie26 · 12/02/2026 20:11

It’s so good to hear all the positive experiences from you all. I was so worried about using MJ and only did so at the suggestion of a dr I saw.

Hopefully it really will be a life reset!

I’m so hopeful, I even asked AI to mix up a photo of me at my goal weight! 😂😂

Theringcycle · 12/02/2026 21:20

Hi all. On week 2 now - did my second injection today. Weighed myself this morning and I’ve gone from 130kg to 126.7. I know there are lots of variables, it’s water and glycogen, it’ll be back up when my period is due etc but I’ve never managed weight loss so effortlessly. Excited to see how this journey unfolds for us all.

Perserverancepayoffplease · 12/02/2026 22:24

wlinewbie26 · 12/02/2026 20:11

It’s so good to hear all the positive experiences from you all. I was so worried about using MJ and only did so at the suggestion of a dr I saw.

Hopefully it really will be a life reset!

I’m so hopeful, I even asked AI to mix up a photo of me at my goal weight! 😂😂

Inspired by this, I've just done the same. It's really weird. Not sure how to feel about it. It's inspiring but also a bit sad making.

RedApplePie · 12/02/2026 22:54

Notellinganyone · 12/02/2026 16:10

It is, Are you generally ok by Monday?

Yes,the last two Sundays I’ve spent utterly miserable swearing I will never take it again, wake up on Monday morning and decide it’s a miracle after all.

Perserverancepayoffplease · 12/02/2026 23:41

Meant to say- I'm perimenopausal and have had far fewer hot flushes since starting the jabs. Interested to know if anyone else has had this.

Notellinganyone · 13/02/2026 09:36

Waaah! I’ve done it. Got myself into a ridiculous state but jab was easy to do. Just worried now that I’m going to start imagining side effects.

Crossfitgirl · 13/02/2026 09:42

InstantRegret · 12/02/2026 14:24

Hi and welcome to any newbies 👋🏻

Jab 3 for me today and a total loss of 6lb so far 😃
Week 1 = -2.5lb
Week 2 = -3.5lb

Happy with that 👍🏻

Getting to the point now where I have to decide whether I’m going to stay on 2.5mg or move up to 5mg. Anyone else pondering on that yet?

I also need to decide whether I’m going to be brave enough to extract the golden dose. Seen so many mixed opinions about it.

Edited

I'm also pondering whether I'll stay on 2.5 or go up to 5. Due to fear of the unknown, I am leaning towards staying on 2.5. I think suppression still feels quite good for me, I'm not really snacking.
I'm due my 3rd jab tomorrow, I don't think we need to decide until after we've done jab 4 though do we - as the next pen will be delivered a week after that? It feels like longer but it's only been 2 full weeks so far so I think I'll see how I feel this next week.
What are you thinking you will do?

I won't be trying to extract any extra doses. Too much faff and worry.

OP posts:
Crossfitgirl · 13/02/2026 09:44

Also, do we know if we can drop back down to 2.5 using the 5mg pen, if we don't get on with the first higher dose? So for example one jab at 5, then 2nd jab can you halve the dose?

OP posts:
RedApplePie · 13/02/2026 10:07

One reason I’m glad I’m just going to a local pharmacy is that she said I could decide about dose increases at the very last minute as they keep all strengths in stock. So I made my review appt for the day that jab 5 is due. At the moment though, just having done 3, I can’t imagine a higher dose but a lot of that is about being scared.

I don’t think there would be a problem with click-counting a lower dose, although you may end up wasting some I guess as it’s meant to be used within 30 days of opening. I may be slightly more relaxed about that if I was storing in fridge but given I’m not I’d be more cautious. Otoh, there isn’t a massive price difference in the lower does so I might suck that up just to see.

MissionToSize10 · 13/02/2026 10:25

InstantRegret · 12/02/2026 14:24

Hi and welcome to any newbies 👋🏻

Jab 3 for me today and a total loss of 6lb so far 😃
Week 1 = -2.5lb
Week 2 = -3.5lb

Happy with that 👍🏻

Getting to the point now where I have to decide whether I’m going to stay on 2.5mg or move up to 5mg. Anyone else pondering on that yet?

I also need to decide whether I’m going to be brave enough to extract the golden dose. Seen so many mixed opinions about it.

Edited

If youre getting good suppression still, maybe stay on 2.5

MissionToSize10 · 13/02/2026 10:31

one thing im making sure i do this time is eating properly. Sounds crazy doesnt it but seriously as the suppression hits, some days i was literally eating two pieces of fruit as i couldnt manage more/wasnt interested. Its not enough. Please make sure youre logging your calories and eating more. I noticed hair loss last time which i think was down to not eating properly. It has come back, i now take Nutrition Geeks Biotin tablets. They’ve made a difference. Now is the time for you to be getting into good habits so when u come off, you're set.

Mediumred · 13/02/2026 10:56

Great hearing everyone’s experiences and tips. About to take my third jab of WG, have lost 2ib this week after not losing at all the first week but am pretty pleased as I don’t have loads to lose, 20Ib would be plenty, haven’t really had any side effects. Did have a little tummy upset this morning but had been out last night and had drunk quite a bit. Wine is a big issue for me and I do think the jabs help a bit.

InstantRegret · 13/02/2026 11:46

@Crossfitgirl my next pen is due the end of next week (I delayed starting it for a week from receiving as I was scared 😆) and you have to decide 3 days before order day with Voy, so I’d have to decide by early next week. Anyway, just looked on the app and I can easily change the date of next delivery so I’m going to do that as it’ll give me an extra few days to decide.

@MissionToSize10 my suppression was non existent in week 1 but really good in week 2. Just a day into week 3 and feeling very hungry so I’ll see if suppression builds over the coming days.
I’m tracking my calorie intake which is set at 1250 but I always go over by at least 100-200 😆 so it’s definitely going to be a slow journey for me!

TheEgg2 · 13/02/2026 11:51

@Wambamaloomaawambamboo please rest assured that I’ve read many, many threads of loads of people saying they were terrified when they did their first jab. It’s completely normal to be really anxious. I’m anxious doing my second one and probably will be each time I do it. There’s also so much riding on this working for us all that we worry about it a lot. Hang in there, you’re with people who totally get how you feel. X

Wambamaloomaawambamboo · 13/02/2026 12:48

TheEgg2 · 13/02/2026 11:51

@Wambamaloomaawambamboo please rest assured that I’ve read many, many threads of loads of people saying they were terrified when they did their first jab. It’s completely normal to be really anxious. I’m anxious doing my second one and probably will be each time I do it. There’s also so much riding on this working for us all that we worry about it a lot. Hang in there, you’re with people who totally get how you feel. X

Thank you for your message, its good to know im not alone. My brain has just taken over this week and i have been thinking all sorts

TwoNicePuppies · 13/02/2026 17:46

After reading other threads from people who’ve been on for a while, we’re going to order a 5mg for hubby, it’s not much more £ (switching pharmacies to get discount) but he can then take 2.5mg, increase to 3.75mg or go straight up to 5mg depending on how he feels/how much he’s lost after dose 4. If we order a 2.5mg he’s stuck at that for another month.

FcukBreastCancer · 14/02/2026 07:56

TwoNicePuppies · 13/02/2026 17:46

After reading other threads from people who’ve been on for a while, we’re going to order a 5mg for hubby, it’s not much more £ (switching pharmacies to get discount) but he can then take 2.5mg, increase to 3.75mg or go straight up to 5mg depending on how he feels/how much he’s lost after dose 4. If we order a 2.5mg he’s stuck at that for another month.

I didnt know you could do that. So you just give more or fewer clicks of pen?

TwoNicePuppies · 14/02/2026 08:02

@FcukBreastCancer yes, we’ve not done it yet as he’s only on 2.5mg, but apparently a full dose is 60 clicks. The plan is to stay on the lowest dose possible for as long as possible as once he gets up to 15mg there’s nowhere left to go and he has a lot to loose!

Helene2019 · 14/02/2026 08:52

Weigh in day. I haven't had any side effects since starting.

Week 1: -3lbs (58.5lbs to go 🤞)

Long journey ahead this year...

groundhogday2day · 14/02/2026 09:28

Well done Helene2019. It's my first weigh day today too. Lost 4lb so very pleased.
I am still going to slimming world as lost 3 st with them a couple of years ago and just can't loose anymore so hoping with this it will help and then not put on when I have got to where I need to be.
The pharmacist did my first jab last Saturday so today will be my first time doing it.

wk 1. Height 5ft. Starting weight 11st 3lb. Now 10st 11 3/4.

WhoInvitedHer · 14/02/2026 10:09

Did my first jab yesterday. Felt nothing with the needle going in and no side effects so far but no suppression either. Early days I know. My question is how much water should I be aiming to drink? I struggle to manage half a litre normally. Does it depend on your height and weight? If I exercise I drink a bit more but can’t imagine drinking more than a litre a day

Wambamaloomaawambamboo · 14/02/2026 12:18

WhoInvitedHer · 14/02/2026 10:09

Did my first jab yesterday. Felt nothing with the needle going in and no side effects so far but no suppression either. Early days I know. My question is how much water should I be aiming to drink? I struggle to manage half a litre normally. Does it depend on your height and weight? If I exercise I drink a bit more but can’t imagine drinking more than a litre a day

You need to drink about 2/3litres of water a day and please do it, I ended up dehydrated and was really ill

RedApplePie · 14/02/2026 13:52

WhoInvitedHer · 14/02/2026 10:09

Did my first jab yesterday. Felt nothing with the needle going in and no side effects so far but no suppression either. Early days I know. My question is how much water should I be aiming to drink? I struggle to manage half a litre normally. Does it depend on your height and weight? If I exercise I drink a bit more but can’t imagine drinking more than a litre a day

Do you drink other things though? It just needs to be (non-alcoholic!) liquid. Pharmacist told me I could count tea/coffee/squash/diet drink/soup and aim for 2.5 litres total liquid in a day. I probably drink 1 to 1.5 as actual water, the rest is made up of other drinks.

StatisticalStitches · 14/02/2026 22:07

Thanks @InstantRegret

I've got some clear whey powder for protein boosts if needed, but hoping not to use it that often.

I've just added some paracetamol to tomorrow's grocery delivery.

Made myself a water tracker to tick off how many times I've refilled my water bottle each day. I am worried about hitting the daily liquid. Especially as I'm super overweight (morbidly obese) so I think I'm meant to be drinking closer to 3L not 2L 😕