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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro/Wegovy with >5 stone/30kg to lose - thread 12!

853 replies

MooBaggage · 29/01/2026 15:40

A supportive, idea-sharing thread for those with more than 5 stone/30kg to lose. We're a mixture of newbies, nearly theres, there and maintaining and we know what it's like to have what can seem like a mountain to climb - but we also know we can do it!

Nothing is off topic except referral codes 😊

OP posts:
Thread gallery
41
Towanda12 · 13/03/2026 12:19

That's really helpful Silence inside..and where I was coming around to as I've spent the morning surfing and Trustpiloting. I also want to stay as long as possible on as low as possible whilst still effective. Pharmulous and shotsy are looking like a starting lineup.
Can you all tell I'm an overthinker?!

TheSlimmingPumpkin · 13/03/2026 13:16

Yep I am also another one who basically has some crepey skin now. I moisture with Aveeno but quite frankly having been obese for so long there is zero chance of getting rid of the wobbly skin now matter how much I exercise and moisturise. That’s a hard truth losing over 6 stone later in life, if MJ had been around in my 30s or early 40s I might have got away with it.

I will not be wearing a bikini and I will not be wearing crop tops nor sleeveless vests nor daisy dukes under any circumstances. And to quote the famous philosopher Lauren from the Catherine Tate show skit with David Tennant -

‘Am I bovverred?’

quite frankly no I am not.

TheSlimmingPumpkin · 13/03/2026 13:21

Towanda12 · 13/03/2026 12:19

That's really helpful Silence inside..and where I was coming around to as I've spent the morning surfing and Trustpiloting. I also want to stay as long as possible on as low as possible whilst still effective. Pharmulous and shotsy are looking like a starting lineup.
Can you all tell I'm an overthinker?!

Pharmulous is a great choice. They don’t bother with any first purchase discounts, points or referral nonsense - just consistent fair pricing. I have never had any delivery issues with them and it has always arrived cool from them which is especially important as we go into the summer (eventually). I had a couple of warm deliveries from Oushk last summer and they said it was all fine even though the ice pack was completed melted.

Questions1234 · 14/03/2026 06:47

Thanks for everyone’s good wishes re: my pet. Thankfully the horrendous grief is easing a bit, and as I thought would happen, my weight has bounced back up again (so back at bmi 25.1) but I’m fine with that!

@Reginaphalangeeeee although I have lost at lot over 15 months, it’s not always been linear! My issue with the losing weight/getting fit in the past was setting myself unrealistic goals, then going “sod it” and giving up when I don’t meet them. So this time, I’ve tried not to focus too far ahead (my only goal to start was to stop the upwards trajectory!!) and kept any goals manageable. So things like - lose 5%, get into the next stone bracket etc. rather than thinking about the end position (which I still don’t exactly know why I’m aiming for). I also keep in mind advise from someone (can’t remember who) on here who said (roughly!) keep plodding forwards - what will you regret more in 6 months; keeping going or stopping. I also discovered I loved exercise if I decoupled it from the weight-loss element. So I choose things I enjoyed, and did them because they enriched my life, not because it meant I could have an extra couple of slices of toast! As it turns out, I’ve ended up in a position I never ever thought possible 18 month ago - both on size and fitness - but I did it by tiny steps and not looking too far ahead, or at others around me. Hope this helps a bit? For completeness I should also say that I see a therapist - mainly for other complications in my life, but obviously my relationship with food/my size comes into a lot of things. So I have had a lot of support in thinking things through as I go. I know not possible for everyone, but helps me loads!

@Towanda12 another vote for Pharmulous. I bounced around lots of providers at the beginning chasing discounts, and settled on Pharmulous for their supportive maintenance position. But their customer service is excellent, as is their option to choose delivery date, and they are well priced.

For those asking about lose skin. I’ve lost 50+kg/8+stone and while my stomach looks like crepe paper (but also to do with pregnancies I think!), and my boobs have looked worse for wear in the last stone, that’s pretty much it. I’ve been religious at moisturising with niva q10 firming cream since early on, but no idea if that’s made a difference- but it’s cheap and I like doing it, so no harm. I’ve also taken collagen powder in my coffee and eaten 1.5-2g protein per kg since the beginning. Again, don’t know if it’s helped or not, but collagen good for my joints and protein fills me up, so all good. But as others have said, it’s a side effect that is totally worth it.

Right, now need to get out of bed and go on my run!!! 🏃‍♀️ Have a good weekend everyone.

SmallTreeDeepRoots · 14/03/2026 11:34

does anyone know if there is a link between MJ and lower blood pressure? I have high BP which I keep an eye on (usually sys of 145ish) but today sys was 122 which is the lowest it’s been for 15 years. I was hoping bp would improve as I lost weight, but it took me by surprise 9 days in. Delighted, but curious and hoping it’s a positive not an bad indicator. Thanks!

MoneyJo · 14/03/2026 12:06

Thanks @Questions1234 the cream you mentioned is pretty cheap on Amazon right now compared to other places so I've just ordered some.

GiveMeWordGames · 14/03/2026 12:14

MoneyJo · 14/03/2026 12:06

Thanks @Questions1234 the cream you mentioned is pretty cheap on Amazon right now compared to other places so I've just ordered some.

The Q10 cream is very popular on this thread. 😁

@SmallTreeDeepRoots yes, MJ is known for its effect on blood pressure, even before you lose significant weight. It had a similar impact on my slightly elevated BP, almost immediately.

@Towanda12 welcome! I'm guessing you're a bit of a fan of "Fried Green Tomatoes......"😊

SmallTreeDeepRoots · 14/03/2026 12:44

@GiveMeWordGames Thanks! That’s good news - now I can celebrate!

@Questions1234 Have also just ordered the Q10 cream. Will slather away like some sort of manifestation of future weight loss.

StatisticalStitches · 14/03/2026 21:47

Amazon will be wondering why Q10 is suddenly very popular 😆 I've ordered the Q10 spf30 face cream, I'm rubbish at remembering to moisturise so hopefully I can improve on that!

alltablenochairs · 14/03/2026 23:49

@SmallTreeDeepRoots yes, MJ affects blood pressure. Amongst other things I have postural orthoststic hypotension syndrome (POTS). MJ has enhanced this. However like everything it's weighing up the positives over the negatives.

@Towanda12 hello and welcome. Of course you're welcome here- this isnt an exclusive club by any means.
In terms of provider, I went with anyone who didnt deliver by Royal Mail. While they're OK in my area for boring mundane stuff like the English Heritage magazine, they just arent reliable enough for MJ. I use Simple Online Pharmacy mainly because they are geographically close-ish to me. The couriers are also OK about leaving parcels over my garden gate as well.
In terms of coaching, I tend to get the most out of this thread. Although everyone's circumstances are slightly different we all have the commonality in that we're in it for the long haul.

Towanda12 · 15/03/2026 08:17

Loved the book and film...seems like a lot of years ago now.Girding up Towanda spirit for the road ahead

Slowrunning · 15/03/2026 09:19

Morning all.
I’ve not been on here for the past couple of weeks so just catching up with all the posts.
I am still at maintenance. Went down from 15mg to 7.5 but really struggled with food noise at 7.5 so for the last 3 weeks have gone back up to 10mg. This is not ideal as I definitely wanted to keep dropping down but I have also been full of cold so am hoping to try again in a week and hopefully will find it easier.

I have been on MJ for 14months and have lost 8 stone going from 105kg to 54kg.
I am at the lower end of my ideal weight but really panic every time my weight goes up at all. I think it’s going to take me another year to get comfortable with being this size!

To answer sone of the recent questions, I am with Pharmulous and find them very good so happy to recommend.

I have loose skin at the top of my arms, thighs, my bum and my stomach. It’s not awful and apart from my arms nobody sees it. It will not stop me wearing a short sleeveless dress when I go abroad in the summer.

What might stop me wearing a short dress though is the fact that I am still continually freezing! I went to the canaries at the end of the year and whilst my husband was happy in a T-shirt I was in a fleece. I am hoping for a nice warm summer so I can put away the ever present thermals.

SecondCircuit · 16/03/2026 15:01

Hello to all newbies! It is a wonderful group offering lots of support and best advice.

Today is my 6 months anniversary on mounjaro, and I have lost exactly 1/4 of former me.
SW 100kg BMI 36.8
CW 75kg BMI 27.5

My work here is not done yet and I need to lose another 2st or so.
The weight loss was greatest at the beginning and is going really slowly now but I really do not want to go up with the doses. I was on 2.5g for roughly 4.5 months and now on 3.75mg for 1.5. Not for financial reasons as much as for the big worry my body will get used to higher doses and I’ll find it very difficult or impossible to wean myself off Mounjaro later on.

I am happy with my 4st loss of course. Yet at the same time, I have a lot of mixed feelings and feel envious of others here.

Nothing is actually falling off me. I can and am still wearing the same clothes. I was size 20 bottoms and I would say am now 16, or 14 if I’m lucky. I can still wear my 20 size jeggings. Tops, that are mostly wool/cotton/merino turtlenecks or tshirts and cardigans combos just fit better.
I still have big boobs (they ve got smaller but travelled further south😖🤗)
Only formal trousers have become too big but I have taken them in at the back and they are still ok. Long winter coats and trench coats have just become looser but I am certainly not drowning in them.

Few people have noticed/observed I’ve lost weight.

Only two from my regular friendship group of 8-10 asked if I have lost some weight; one colleague that I haven’t seen for a year exclaimed with genuine glee „Gosh, you’ve lost some weight, haven't you? You look stunning!” (obviously exaggerated but I was pleased as a peach to hear such compliment😊) but none of my other colleagues who I don’t see every day but regularly have noticed/made any observations.

So my take is:
I have lost weight but it’s probably not that much noticeable.

I’m not sure how much more I will be able to lose. As far as I remember I was always 66kg in high school, uni years and throughout my 20. and 30. After that and dc I steadily have been aquiring new kilograms each year. Can I get to 65kg or below considering my age now? Can I maintain it?

My initial febrile excitement is long gone. I want to remain optimistic but am sceptical. So I won’t be getting rid of any clothes. A bit of a shame, but well, at the moment my mind is still playing a game of pernicious thinking.

Gosh, sorry for this long post.
This weight loss journey is a rollercoaster of emotions. One day happy and elated, next - thoroughly disappointed🤗🤗

MooBaggage · 16/03/2026 15:07

@SecondCircuit I echo the rollercoaster riding feeling! I'm not sure that it ever goes away? You are doing incredibly well - to have lost that in just 6 months - just amazing...!

I think my weight loss has only become significantly noticeable in the last couple of stones off - so at the point of losing over 5 stone I suppose more people have commented. The paper towel analogy is definitely real! Right now, I feel OK-ish, but really want to lose 1lb this week to hit my 7 stone loss. If I don't, I know I'll feel miserable, which is just ridiculous 🙄 I feel like I'm racing against time to hit my goal (about 21lbs to go), but the only clock is myself 🙄

OP posts:
SecondCircuit · 16/03/2026 15:25

I absolutely understand this feeling @MooBaggage !
I was racing to lose the last kg of this 25kg loss for my 6months on MJ. And the bloody kilogram has been bobbing up and down for aaages!

And I am still waiting for my collar bone to show up - I remember your post and photo from previous threads months ago and I’ve been on the lookout for mine ever since!😅

RobinEllacotStrike · 16/03/2026 15:52

I do have some saggy/wrinkly skin after going from BMI 41 to 24 (52 kilos) however I'm not bothered as everyone is dazzled by my glorious face framing new collarbones & shoulders.

TheSlimmingPumpkin · 16/03/2026 15:56

@SecondCircuit get yourself into the shops and try on different sizes. I was forced to by my daughter who got fed up of my ‘clown’ trousers and baggy clothes. Everyone then started commenting upon how much weight I had lost.

Don’t buy black. And don’t buy ‘tents’ IYSWIM

GiveMeWordGames · 16/03/2026 17:13

@SecondCircuit you are almost exactly where I was in late September: 6 months in, just under 4 stone down with 2 stone more to go having started at a size 20 (on the bottom, anyway - bigger on top).

As it happens, I was just now looking back over my Vinted transactions to see how much I've spent (don't ask!!!) and I didn't open my account until early October and even then I started out buying coats primarily because I needed new coats anyway. I'd only moved down one size in jeans at that point, to an 18, and was shopping my wardrobe with those. I was desperate to fit into an old Tu size 16 pair I'd kept but I wasn't there yet.

Nobody apart from my Mum (who mostly wanted to check I wasn't wasting away from some illness 😐) had commented on me losing weight. I think some deluded part of my brain had thought I'd be mostly done by Sept. And yes, from that point on, the loss slowed right down. It's taken me the same amount of time to lose the last 2 stone as it did the first 4 but the impact on my size has been far more dramatic. Yep, the paper towel roll analogy is really real!!

It is SUCH a rollercoaster and you've done amazingly to lose so much on such a low dose (I was on 7.5 by 6 months). Hang in there. You've got this.💪

SecondCircuit · 16/03/2026 18:23

Thank you ladies for your advice and encouraging words. They help a lot♥️♥️

Without this group I would’ve likely chucked the MJ pens deep into the corner in frustration long ago!😁

ShrankLastWinter · 16/03/2026 22:14

@SecondCircuit what everyone is saying here is my experience too. The difference from 27.5 to the healthy BMI bracket isn’t many kilos but it’s huge in appearance (and health) terms.

ShrankLastWinter · 16/03/2026 22:20

On the loose skin, I’ve lost 1/3 of my starting weight and I have some crepey wobbly bits - tops of inner thighs and tummy. But it’s really minimal and I think those bits were pretty stretchmarked and wobbly when I started. They’ve improved in maintenance. I think exercise is making a big difference.

RobinEllacotStrike · 17/03/2026 12:35

@SecondCircuit it does give me a chuckle when GLP1 is always spoken of as "rapid weight loss". the 2nd 25kg I lost took twice as long as the first 25kgs with many long plateaus. Average loss of approx 2.5kgs a month - its good, its steady but not what I would call rapid.

Keep an eye on your exercise & healthy diet/calorie deficit & keep going. You'll get there.

MooBaggage · 18/03/2026 07:37

Woohoo! Happy day today - I've hit my 7 stone loss 😮

13.1.25 SW 20st 3lb BMI 43.0
18.3.26 CW 13st 3lb BMI 28.0

Now did I shuffle the scales around the bathroom floor when it initially told me I was 13st 4lb 0 oz? Yes I did 😀 Then it thought again and gave me 13st 3lbs 4oz, which was much better...!

Next little target - 100lbs loss, in 2lbs' time. And then the very scary 12 stone something, which truly will be a foreign land to me as I genuinely can't remember ever being 12 stone anything - must have been as a young teenager.

21lbs to go until a healthy BMI - let's goooooooo..... 💪💪💪

OP posts:
MoneyJo · 18/03/2026 07:41

Wow @MooBaggage that's amazing! How long has this taken you?

I was a bit below your start weight a year ago, lost a stone and a half on my own and another half now on MJ. Almost 5 stone to go to get where you are but you give me hope!

Towanda12 · 18/03/2026 08:11

Congratulations @MooBaggage , that's a wonderful outcome and inspires me. Steady loss over 14 months..grit, determination and staying power on display. Here's to the next tranche. Best wishes