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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

April 2025 Mounjaro Starters - Thread 6!

313 replies

Uninvitedleaf · 12/11/2025 15:34

New thread for when number 5 is full and so I can link to it in good time!

OP posts:
Thread gallery
14
lbnblbnb · 01/02/2026 18:52

After losing my way a bit over Christmas, I am now just above the healthy range - 1.2lb to go. So should get into the healthy range this week. Very exciting.

i think I will aim to get .5 stone into the healthy range, then reassess. I am on 15mg currently, wondering about starting to taper after the next pen that I already have (I get the fifth dose out of every pen, so that would be in six weeks time).

Also wondering about doing something to celebrate my year anniversary. Only one close friend knows I am using MJ so can’t be something too obvious.

SW April 25: 14 7.9
CW: 11 2.4
Lost: 3 5.5
Target W: maybe 10 7 ? Or possibly 10?

Good luck everyone.

Uninvitedleaf · 01/02/2026 22:14

@lbnblbnb that’s brilliant news.

Is there anything you feel like you put off or were too self conscious to do when you were heavier that you could try out or treat yourself to now? I’m partly thinking of the spa afternoon that I mentioned I did last week. The afternoon was lovely but it was a huge boost for me not to be self-conscious about being given a too-small robe which is such a trivial thing but would have really put me off doing it in the past. I’m sure no one else would even have noticed but I enjoyed myself so much more because I felt just average sized for once. Just thinking if there's anything you wouldn’t have considered previously, however small, you could go for it now to mark the new you!

OP posts:
Pepperwaggytail · 01/02/2026 22:20

QS90 · 30/01/2026 09:57

@pepperwaggytail It's interesting you say "I feel like MJ has fixed whatever is broken in my body". Michael Mosley (RIP), when he was purposely putting on weight for his research on the Fast 800, also found that his body was initially resistant to gaining weight / cholesterol going up etc. I recently listened to a Zoe podcast, that might explain it. Basically, when a person's blood sugar is shot, it makes the body feel hungry all the time, because the body can't accurately sense how much fat it is carrying. As it thinks it's starving, even as it's overweight, it puts measures in place to stop you from starving, so weight goes on a lot more easily. Once a person's blood sugar is improved, and consequently leptin(?) and the other hormones affected, are also stabilised, the body can "see" that it isn't starving. Quite plausibly, that was what was broken and is now fixed!

Goodness what a long and nerdy post!!

How interesting! I need to find that podcast and have a listen! I feel my weight is very stable at the moment on 2.5mg a week. That’s even with that nasty cold/lurgy that’s doing the rounds - I’ve been very off colour for a week and eating has been all over the place.

QS90 · 01/02/2026 22:26

Sorry to hear you're feeling under the weather @Pepperwaggytail The podcast is the one in the image attached, if you are interested in a bit of light bedtime listening.

Youngest has chickenpox in our house - apparently that's doing the rounds too. He's been up at night, and the tiredness has been making me feel a bit snackier than usual. Still, I'm at work tomorrow, so partner on toddler duty tonight!

April 2025 Mounjaro Starters - Thread 6!
lbnblbnb · 01/02/2026 23:14

Uninvitedleaf · 01/02/2026 22:14

@lbnblbnb that’s brilliant news.

Is there anything you feel like you put off or were too self conscious to do when you were heavier that you could try out or treat yourself to now? I’m partly thinking of the spa afternoon that I mentioned I did last week. The afternoon was lovely but it was a huge boost for me not to be self-conscious about being given a too-small robe which is such a trivial thing but would have really put me off doing it in the past. I’m sure no one else would even have noticed but I enjoyed myself so much more because I felt just average sized for once. Just thinking if there's anything you wouldn’t have considered previously, however small, you could go for it now to mark the new you!

Edited

That is a good idea @Uninvitedleaf - I’ll have a think. I did wear bikinis for the first time since I was about 20 last October. What else have I been putting off?

Mumof2studentnurse · 03/02/2026 17:12

Hi, I hope you are all doing great :) I've just had a little read over some updates and it looks like everyone is still doing so well :)

Things with me have been really, really good. I'm not really sure where I left things off. Things were quite awful in my life....my ex husband has not been in touch with our children since October. He didn't give them a Christmas card or a Christmas gift. It was our daughters birthday last week, and again, he didn't so much as send her a birthday card or make any attempt to contact her. She's only 8 years old. But the weird thing is...I am happier than ever.

I had such a great Christmas with my kids. We live our lives, just the three of us, and we are all very, very happy. So this isn't a tragic story.

As far as weight goes, I'm still on Mounjaro, im thinking of coming off it or reducing the dose because the price is killing me now, and i can't keep it up much longer.

On April 9th 2025 I was 21st 9lbs. Today I am 10st 11lbs. So I am 2lbs away from an 11 stone loss.

I feel great. Today i'm wearing size 12 jeans! I'm a size 10 on top. My jammies (stretchy) are size 8-10. I look in the mirror and don't recognise myself, in the best possible way. I make a massive effort with my appearance now. I style my hair every day, I wear make-up again, i re-apply my lipstick throughout the day, i enjoy buying clothes. I take photos of myself with my kids, I take selfies and post them on Facebook, I have a social life now, and I don't say no to doing things because of my weight.

I can't believe how much my entire life has changed since April. I could cry from happiness. Don't get me wrong, my body needs a whole load of toning up and maybe even surgery to fix it properly...but i've probably increased my life expectancy by several years, and I have so much fun with my kids now. Being able to chase after them and keep up with them is something that I would never have imagined being able to do.

I'm so grateful that mounjaro exists, because i would be living a very unhappy and unhealthy life today without it! x

Pepperwaggytail · 03/02/2026 21:22

Mumof2studentnurse · 03/02/2026 17:12

Hi, I hope you are all doing great :) I've just had a little read over some updates and it looks like everyone is still doing so well :)

Things with me have been really, really good. I'm not really sure where I left things off. Things were quite awful in my life....my ex husband has not been in touch with our children since October. He didn't give them a Christmas card or a Christmas gift. It was our daughters birthday last week, and again, he didn't so much as send her a birthday card or make any attempt to contact her. She's only 8 years old. But the weird thing is...I am happier than ever.

I had such a great Christmas with my kids. We live our lives, just the three of us, and we are all very, very happy. So this isn't a tragic story.

As far as weight goes, I'm still on Mounjaro, im thinking of coming off it or reducing the dose because the price is killing me now, and i can't keep it up much longer.

On April 9th 2025 I was 21st 9lbs. Today I am 10st 11lbs. So I am 2lbs away from an 11 stone loss.

I feel great. Today i'm wearing size 12 jeans! I'm a size 10 on top. My jammies (stretchy) are size 8-10. I look in the mirror and don't recognise myself, in the best possible way. I make a massive effort with my appearance now. I style my hair every day, I wear make-up again, i re-apply my lipstick throughout the day, i enjoy buying clothes. I take photos of myself with my kids, I take selfies and post them on Facebook, I have a social life now, and I don't say no to doing things because of my weight.

I can't believe how much my entire life has changed since April. I could cry from happiness. Don't get me wrong, my body needs a whole load of toning up and maybe even surgery to fix it properly...but i've probably increased my life expectancy by several years, and I have so much fun with my kids now. Being able to chase after them and keep up with them is something that I would never have imagined being able to do.

I'm so grateful that mounjaro exists, because i would be living a very unhappy and unhealthy life today without it! x

Just WOW!!!
You go girl!!
It’s very good to hear from you! We were all a bit worried how you were getting on. You’ve shed a very toxic person from your life and you seem to be thriving!
Please stay in touch with us if you have time.
Big hug from me 😘

lbnblbnb · 07/02/2026 17:10

Still hovering just inside the healthy BMI range. Which is still amazing to me.

I have decided what I want to do to celebrate - dancing. I have no confidence and feel incredibly self conscious about dancing, so am going to find ways to loosen up and get more comfortable. Nothing spectacular, not Simply Come Dancing or anything. I would just like to be at a party and dance and not feel awkward. So going to think about how to work on that.

Pepperwaggytail · 07/02/2026 21:54

lbnblbnb · 07/02/2026 17:10

Still hovering just inside the healthy BMI range. Which is still amazing to me.

I have decided what I want to do to celebrate - dancing. I have no confidence and feel incredibly self conscious about dancing, so am going to find ways to loosen up and get more comfortable. Nothing spectacular, not Simply Come Dancing or anything. I would just like to be at a party and dance and not feel awkward. So going to think about how to work on that.

Fantastic that you have the confidence now to do this! Enjoy! ☺️

QS90 · 07/02/2026 22:29

lbnblbnb · 07/02/2026 17:10

Still hovering just inside the healthy BMI range. Which is still amazing to me.

I have decided what I want to do to celebrate - dancing. I have no confidence and feel incredibly self conscious about dancing, so am going to find ways to loosen up and get more comfortable. Nothing spectacular, not Simply Come Dancing or anything. I would just like to be at a party and dance and not feel awkward. So going to think about how to work on that.

Ooooh, maybe even a dance class?? Even just jazz-ercise or something at the gym, rather than anything too serious. I have always thought that sounded like such a lot of fun. Thinking about it, I might even see if my gym has something similar 🤔

SaddlebagSal · 15/02/2026 19:39

Hello everyone, it’s been a while. I’m still plodding away, and since I last posted I’ve enjoyed both a holiday abroad and Christmas by plateauing weight and not putting any on. Unheard of for me.

Heaviest: 14 st 10 lb
SW: 14 st 1.5lb (BMI 33)
CW: 11st 7 lb (BMI 26.5)
TW: 10 st 7 lb.

I was delighted to get to overweight instead of obese, and “normal” is in sight. I think I’ve suddenly lost some fat from round my face as I’ve recently got quite a few comments. It does feel like my body shape has started to adjust and my bosom is not quite so matronly. Still got plenty to lose around my bum and thighs though.

NSV that put a great big smile on my face this weekend: I dug out a posh dress I last wore for an Event in 1996 and it fits! In fact it looks better than it did 30 years ago but that’s again because my proportions are different now. So I know exactly when I was last this weight. I also tried on a dress I got for my 21st birthday a few years previous - I could do up the zip but it was a bit tight. At a push I could wear it now with some strong shapewear underneath but if I get to goal I should be able to wear it and breathe at the same time!

I’m on 15mg pens but only taking 12.5 at the moment. Currently losing about 0.5lb a week, that is eating 1000 calories a day. Hopefully with the days getting longer and the weather getting better I’ll feel more able to go out and get some exercise which will help.

Pepperwaggytail · 16/02/2026 08:10

Hello everyone- I’m plodding away too. I’ve still not lost that 2lb I put on over Xmas 😡 though to be fair I’ve not tried much, and not really that bothered! BUT I’ve gone from 9st 7lb pre Xmas to 9st 9.9lb on Friday and I’m feeling like it’s going in the wrong direction. So I’ve upped my dose to 3.15ml yesterday and been a bit more careful. I’ve just weighed at 9st 8.8lb so phew! I know realistically I’ve probably just lost water but my head is now in a better place. I hate how much the numbers on the scale mess with my head!! 50 years of training!! 🥺
I also did a body composition weigh in yesterday (last one was in October when I weighed 9st 12lb) and I have decreased subcutaneous and visceral fat since that. Everything else has stayed the same same really.

Anyway, hope you are all doing well, do a little update when you can. 😘

WinterOnItsWayOut · 16/02/2026 08:27

Well done everyone for KOKO…

SW:12.12 (BMI 30.3)
TW: 10.5 (-2.5 stone - BMI 24.2)
CW: 10.4 (BMI 24.1)
Lowest: 10.1

Body fat has decreased from 45% 🙈 to 33.7% 🙌. I don’t think my scales are particularly accurate in this regard but the direction and quantum of travel is very pleasing. I’ve been doing the 30 Day Shred which has definitely helped and swapping muscle for fat is probably contributing to not losing more weight. I am also just back from a few days away so hopefully a couple of pounds will come off as I go back to pre holiday eating…. 🤞

I have come down to 1.25mg (was on 2.5 all the way through until the start of Jan) and have 2 jabs left and then it’s me on my own 😬. I didn’t envisage taking it for so long and recognise it’s become a bit of a crutch so will see what happens in the next couple of months….

Would be great to hear how everyone else is getting on 10 months in 😊

SusanSometimes · 16/02/2026 09:18

Still here, also still plodding along! Weight loss as always is slow and steady, only about half a pound a week, but that's OK, I'll get there. I'm grateful for MJ as I wouldn't have got this far without it, that's for sure.

RhaenysRocks · 16/02/2026 10:18

Also still here and only half way to goal .. have really plateaued since Xmas but I'm not going higher than 7.5. It's v v slowly inching off though and thats OK, it took decades to reach my sw of 14.7 so if it takes two years to get to 9.7 thats OK. Fantastic news from some here, especially @Mumof2studentnurse . I hope your ex chokes on his dinner..what a waste of space these men are. I.hope your kids are OK with his absence x

RhaenysRocks · 16/02/2026 11:42

Also still here and only half way to goal .. have really plateaued since Xmas but I'm not going higher than 7.5. It's v v slowly inching off though and thats OK, it took decades to reach my sw of 14.7 so if it takes two years to get to 9.7 thats OK. Fantastic news from some here, especially @Mumof2studentnurse . I hope your ex chokes on his dinner..what a waste of space these men are. I.hope your kids are OK with his absence x

SusanSometimes · 16/02/2026 12:54

@RhaenysRocks I'm also still on 7.5mg and not planning to go higher. I'd say I'm about two fifths away from goal at this stage, and if it takes me until Christmas to lose the last couple of stone I don't mind.

Uninvitedleaf · 16/02/2026 14:17

Much the same from me - still here, I've only gone up to 6.25mg (intended 7.5 but used this as an interim step and it seems to be working so I am sticking with it). Slow losses but it's all going in the right direction and I'm actually pretty happy at on or just under 1lb/week coming off. I've lost just over 3st overall (🤯). My BMI is still well above where it should be (around 28) and I probably have about a stone and a half to go so I'm around 70% of the way there and 30% to go. The rest might well take me another 6 months to a year but that would be OK.

In other news I am just about to accept a voluntary severance offer from work (they don't know I am going to accept - still pretending I am thinking about it to see if I can get a bit more out of them) and that would mean starting early retirement around the end of May. It will be a good opportunity to up my exercise a bit more, I am doing better with that but still plenty of room for improvement! I've dropped a good bit of body fat too but not as good as yours @WinterOnItsWayOut - think mine has gone from 44% to about 39% which is still way too high. Waist measurement has come down to about 32" though so at least I know that's approaching the healthier range.

OP posts:
QS90 · 16/02/2026 17:34

Hello all, glad to hear all of your updates!

@SaddlebagSal you are doing so well. Just thinking out loud though, 1,000 really isn't very many calories at all! If you were to maintain weight for a bit, do you think weightloss would be quicker over all? As your metabolism might increase a bit? Make sure you're getting all your protein too, so your muscle is conserved. Sorry to be preachy, you probably have thought about all of this already!

I've weaned down from 15mg Monjaro to 1.7mg Wegovy (the middle one). Still very slowly losing weight, since going into maintenance and since moving on to Wegovy 6 weeks ago both (graphs attached, if anyone is interested). Used the fancy scales at the gym and was pleased with what it showed re muscle etc too.

Bad news is that I've been quite under the weather with some horrid virus, currently on Day 12 ☹️ Actually took the day off work today and have been asleep most of the day. Twice over the last couple of weeks I've felt a bit better, then had a normal day at the gym and taking the kiddies out, only to be back very unwell the day after. Can't smell or taste anything, so it could be Covid (then "Rebound Covid", which is also apparently a thing). Can't help but wonder if the weight loss has negatively impacted my ability to fight of viruses? Have skipped a dose of Wegovy as appetite has been low anyway.

April 2025 Mounjaro Starters - Thread 6!
April 2025 Mounjaro Starters - Thread 6!
April 2025 Mounjaro Starters - Thread 6!
Pepperwaggytail · 16/02/2026 19:09

QS90
i think that horrible virus has floored most people including my super fit husband, so I wouldn’t worry too much. If anything you are more likely to be healthier and have less inflammation.
It sounds like you are doing well on wegovy, I’m tempted to try it just for the price when I’ve used up all my MJ stash. Please do keep us updated 😊
Ive had a couple of days feeling queasy after a tiny dose increase, after a drop for a few months, so im assuming that the MJ is still working after 10 months 😎

SaddlebagSal · 17/02/2026 08:26

@QS90 no worries! Yes 1000 calories isn’t much. I’ve never eaten breakfast as an adult, I just can’t face food in the morning, so it’s not too bad spreading 1000 calories over two meals. However, many days it’s more like 1200 calories which is why I’m only losing 0.5lb a week.

I’m very sedentary at the moment for various reasons, so I’m hoping that if I can move about a bit more it will help. I’m not worried - as I’ve not been my current weight for 30 years I think I’ve also reached a set point where my body is fighting going any lower. I’ll keep plugging away, getting in that old dress was such a motivator!

SquishyGloopyBum · 17/02/2026 09:56

Still here also.

im currently my lowest weight at 10st 3 - which is 3stone loss overall. I’m in maintenance but not ready to give up the mounjaro yet. Yes it’s a crutch but it’s so freeing. I’m hoping to stay on and switch to tablets eventually.

keep going everyone!! This time last year I was so miserable and unhappy with myself. It took me a couple of months to take the plunge and I’m so glad I did.

PhantomErik · 17/02/2026 15:32

Also still here & feeling better overall than last month (& much better than last year!) Using my fitness pal has made me really look at my diet & showed where I need to improve which is basically more protein & sometimes more calories. But I think it’s having a positive effect as I’ve lost another 2lbs & finally broken the 13 stone barrier so now weighing in at 12.12 after starting at 16.6 this feels amazing.

Played badminton with teen DS’s & surprised myself & them at how well I played. It was funny as it was like my body moved quicker than I was expecting & I wasn’t really out of breath for more than a few seconds. Quite eye opening!

I’m micro-dosing as I found 12.5 too much in 1 go but after a week found 10mg a bit low so I’m doing 9mg on Sunday & 4mg on Thursday. So far it feels about right.

I wish I was someone who could manage on a very low dose & I’m slightly worried about relying on it. However, right from the start I’ve thought I’d get the weight off first & worry about maintaining at that point.

SunnySpellsAhead · 23/02/2026 09:18

Hi, Team April. Hope everyone's doing well and recovering from the winter bugs and blues. I'm starting to unhibernate now but so pleased that life on MJ has been pretty smooth and that the new way of eating is really embedded now. Still have the odd hiccup when the sweet tooth reappears, usually in stressy times, but can then just start again the next day - still unbelievable!

It's now taking around 12 weeks to lose a stone compared to 8 or 9 at the beginning. Latest stats:
CW 11st 5.2lb, BMI 29.3.
Loss 5st 3lb.

My body fat is still a terrible 39.7% from a previous 46.4% according to my lying scales, so a way to go yet, even though I'm fairly happy with how I look and would be overjoyed if this was it for the rest of my life.

I listened to the Oushk recording for the first time, with the infamous Hira, where she said that the new follow on MJ pills from Eli Lilly will be more suitable for those on lower doses of MJ, possibly available at the end of the year. The new triple GLP-1 also sounds brilliant for those starting their journey but high prices expected again when it's available. Fingers crossed the pills will be a bit more affordable.

Pepperwaggytail · 23/02/2026 22:21

Good to hear from everyone ☺️ this is a long slow road to health and fitness so stay positive! You are all doing so well.
I did a 10k fun run at the weekend and amazed myself by actually enjoying it! I’ve also just realised that I’ve not had any gaviscon tablets (for GERD) for ages! I used to stockpile them nor they are going soft in my handbags!
Small wins!
😘

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