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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

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25
LnicMJ · 24/09/2025 16:04

@justjuggling well done! Can I ask how many weeks you're at etc as I find it helpful when im having a slump to see others with the woosh after 🤣🤦‍♀️

LaGioiosanotLeviosa · 24/09/2025 17:40

I’ve got weigh in tomorrow, hoping to get my 1lb for a stone loss.
weirdly I feel fatter than usual. I’m doing all the right things and it’s not time of the month. I’m quite constipated I guess but it’s so odd to be feeling bigger than I usually do.
anyone else felt like this?

Haribosweets · 24/09/2025 18:24

Hi, been a week since I last posted so much to catch up on! Hope the poster who is in hospital is ok now? Really hope its not the MJ.
So after me wondering whether to go upto 5 last week I had such high suppression since so ordered my 3rd 2.5.

Ive just done week 6 and 1st 2ib down. Feeling happy with that and hope it continues. Its my birthday in October so worried about a pre planned event with alcohol and going away at end of month.

When I have gained in the past it takes ages to lose again so worried this will happen again if I do gain. Typically the event and holiday are a week apart!

justjuggling · 25/09/2025 01:47

LnicMJ · 24/09/2025 16:04

@justjuggling well done! Can I ask how many weeks you're at etc as I find it helpful when im having a slump to see others with the woosh after 🤣🤦‍♀️

Hi @LnicMJ Ive just started week 100 so had a whoosh on week 9 following disappointing weeks 7 & 8. Not sure what caused the whoosh! 🤷‍♀️

LaGioiosanotLeviosa · 25/09/2025 07:41

So despite feeling like I’ve lost nothing, I’ve lost another 2lbs this week!
So thats just over 1 stone in 6 weeks. I’m a third of the way there but no drop in dress size yet so hoping to get through this next stone quickly to see some changes!

AsteriaBuffy · 25/09/2025 09:15

Weigh in day yesterday, a whole pound down but took me to just under 14 stone so definitely a breakthrough! Averaged a pound a week for 8 weeks.

Also took 5mg for the first time - a palaver splitting it over 2 pens - golden dose from a 2.5mg pen, and 30 clicks from a 5mg pen. Used an insulin syringe for the first time to get golden dose which didn't go well as after extracting, the needle was too blunt - must have bent it a bit somewhere. So had to decant into a fresh syringe (being careful to get rid of air) which thankfully did work.

Anyone else having clothes crisis? Going into autumn clothes has brought it back to me how rubbish my 'fat hibernating' wardrobe was. I was looking forward to stuff looking better on me but if anything it looks worse - droopy, overly voluminous and faded!! I was also hoping jeans would be more comfortable but not really, they just don't fit properly (or are STILL too tight, grr). Time for some shopping!

Texanchilli · 25/09/2025 11:17

Weigh in day for me this morning. After a disappointing 2 weeks, I lost 2lb this week. That brings me to 8.5lb from my first pen, including the extra dose. I would have rather a bigger loss but I’m reasonably happy with that.

I need to take my next dose today and I cannot decide what dose to take. I have a 5mg pen. I’m wary of taking 5mg because of the side effects. I’ve felt pretty sick most days since I started MJ. I’ve had a lot of headaches too. I think I’ll go with 3.75mg this week.

saywhaaaaaat · 25/09/2025 12:29

I think I mentioned but yesterday I changed my injection site and definitely feeling the suppression more... could be because I'm more aware. Dunno, might stick with 2.5mg next and see how that goes. Also weighed this morning and back down to 85.7kg, which was my lowest so hopefully a little woosh is coming.

Pumpernickelbrakes · 25/09/2025 17:23

I had a headache yesterday, and strong suppression yesterday and today. I took my first 3.75mg on Monday. Really cannot be bothered to eat at all. Have soup and salad and oatmeal with yogurt and frozen berries as options and meh about all of them. Currently battling an ant infestation and filthy from crawling about in cupboards looking for the little bastards.

still no movement on scales. Been at 180.something- 181.5lb up and down for two weeks.

No time to exercise today. Maybe all the exercise is what’s stopping the weight loss. Who knows?

Somethingsnapped · 25/09/2025 17:27

Texanchilli · 25/09/2025 11:17

Weigh in day for me this morning. After a disappointing 2 weeks, I lost 2lb this week. That brings me to 8.5lb from my first pen, including the extra dose. I would have rather a bigger loss but I’m reasonably happy with that.

I need to take my next dose today and I cannot decide what dose to take. I have a 5mg pen. I’m wary of taking 5mg because of the side effects. I’ve felt pretty sick most days since I started MJ. I’ve had a lot of headaches too. I think I’ll go with 3.75mg this week.

Do you mind me asking why you decided to go up to 5mg? From what I've read, if you're experiencing side effects, it's recommended to stay on the lower dose for a while. They recommend going up a dose if no side effects. Feeling sick most days is quite intense. There is no need to go up a dose every month.

As for the nausea, that sounds unpleasant. Have you tried peppermint oil capsules or fennel tea?

Texanchilli · 25/09/2025 17:33

I ordered the 5mg pen the day after I took my first dose in a panic when all the prices were going up. I can’t afford to keep going so this will be my last pen.

I’ve not taken anything for the sickness. I tried everything when I had morning sickness and nothing helped. I guess it’s worth a shot now though.

Somethingsnapped · 25/09/2025 19:18

Texanchilli · 25/09/2025 17:33

I ordered the 5mg pen the day after I took my first dose in a panic when all the prices were going up. I can’t afford to keep going so this will be my last pen.

I’ve not taken anything for the sickness. I tried everything when I had morning sickness and nothing helped. I guess it’s worth a shot now though.

Could you count clicks and take half doses each time to stay on 2.5? It would last longer too. Perhaps keep it in the fridge inbetween? I know that would mean it was open longer than it's supposed to, but I do think other people do this? Does anyone know?

MrJollyLivesNextDoor · 25/09/2025 20:28

Somethingsnapped · 25/09/2025 19:18

Could you count clicks and take half doses each time to stay on 2.5? It would last longer too. Perhaps keep it in the fridge inbetween? I know that would mean it was open longer than it's supposed to, but I do think other people do this? Does anyone know?

I would definitely do this. I can’t believe it suddenly goes off after the 30 day expiry

OP posts:
MrsSuu · 25/09/2025 20:47

Has anyone totally hit a brick wall in the second month? I stayed on the 2.5 pen and even though I’m only eating a piece of fruit for breakfast, a small lunch and dinner I haven’t dropped at all. I don’t really have the supression like I had in the first few weeks. I don’t really feeling hungry but I can eat lunch and dinner without feeling full. I’m worried about moving to the 5 pen due to the cost and side effects.

sfraxx · 25/09/2025 21:13

Good evening guys, well first week off MJ and I’ve maintained at 11st5lbs. My scales haven’t even moved up or down by 1 ounce. To be fair, the food noise is horrendous so I’m having to have so much will power but I am not eating any different to when I was on MJ yet not losing. Weigh day isn’t until Monday though so maybe over the weekend but I doubt it, we’re away to the caravan as it’s September break for the school so with food noise and lots of fast food, I hope I can be good lol. I plan to be.

I have no gallstones and bloods okay, but after an endoscopy my stomach is extremely inflamed and they’ve taken samples. I already had acid reflux but when on MJ I did suffer 10x worse, must just have counteracted with it.
now I’ve got the all clear for gallstones. I’m going to pop back into pharmacy next week, my medication has been up from 1 to 4 tablets per day so maybe this could help? Who knows. I can only ask, I won’t do anything that’ll potentially make me unwell. But I’m hoping I get the ok to start again as it’s a great feeling seeing the scales coming down. I’ve went down a whole dress size in 4 weeks on MJ. Xx

NeedSleepNow · 25/09/2025 22:36

MrsSuu · 25/09/2025 20:47

Has anyone totally hit a brick wall in the second month? I stayed on the 2.5 pen and even though I’m only eating a piece of fruit for breakfast, a small lunch and dinner I haven’t dropped at all. I don’t really have the supression like I had in the first few weeks. I don’t really feeling hungry but I can eat lunch and dinner without feeling full. I’m worried about moving to the 5 pen due to the cost and side effects.

This is how I've found the second month on 2.5mg. The for 3 of those weeks I've basically stayed the same weight despite not eating much. I don't feel hugely hungry but can easily eat a lot at mealtimes if I let myself. I have eaten more this week and have lost a pound so I wonder if my calories were too low the last few weeks and perhaps if I eat a bit more I might get back to losing each week.

I start my 5mg pen tomorrow but I'm still undecided whether to go straight to 5 or if I should try 3.75mg first and see how it goes. Like you I'm worried about side effects

MrsSuu · 25/09/2025 22:38

NeedSleepNow · 25/09/2025 22:36

This is how I've found the second month on 2.5mg. The for 3 of those weeks I've basically stayed the same weight despite not eating much. I don't feel hugely hungry but can easily eat a lot at mealtimes if I let myself. I have eaten more this week and have lost a pound so I wonder if my calories were too low the last few weeks and perhaps if I eat a bit more I might get back to losing each week.

I start my 5mg pen tomorrow but I'm still undecided whether to go straight to 5 or if I should try 3.75mg first and see how it goes. Like you I'm worried about side effects

Keep me updated! 3.75 might be a good idea x

LaGioiosanotLeviosa · 26/09/2025 07:53

Just really want to say for anyone worried about going to 5mg. If you’ve not really had any side effects on 2.5 apart from the usual tiredness and constipation that tc I really recommend going straight to 5.
I totally get people going up carefully if it’s been rough for them so this post isn’t for them but in general I think going straight to 5 really keeps you weightloss going as intended.
Ive read so many of the threads on here and the one thing that stood out was people who stuck on 2.5 for the second month (and often those who did two months on 5) stopped losing. There are some people who the lower doses give super strong suppression which is so amazing but I really think they are the ones exception not the rule and it’s made people think they should be the same?
I had no side effects going to 5 (less than when I started 2.5) and I expect will also go to 7.5 after my golden dose on the 5 pen. It’s only then that I may stick another month on 7.5.
Anyway just wanted to lend some encouragement to anyone feeling nervous about going up that’s all!

Pumpernickelbrakes · 26/09/2025 20:01

Am really glad I stopped persisting with 2.5mg which felt like it wasn’t doing anything after the first 4 weeks and went up to 3.75mg for week 7.

Yesterday and today the suppression is good, my energy is back, I feel like things are working again. The only side effect was the headache yesterday and that could have been down to dehydration because I was so busy. I had no side effects on 2.5mg apart from a few days constipation in the first week which went away when I used magnesium citrate.

And today the scales have finally moved below 180lb 🥳

On Monday my plan is to do another 3.75mg using the last of this pen and then I’ll be onto my 5mg pen that I bought in late August.

SkinnyOatFlatWhiteForMePlease · 26/09/2025 21:40

Thats great @Pumpernickelbrakes, glad you feel better.

I moved up to 4mg today, so far so good.

Pumpernickelbrakes · 26/09/2025 22:45

sfraxx · 25/09/2025 21:13

Good evening guys, well first week off MJ and I’ve maintained at 11st5lbs. My scales haven’t even moved up or down by 1 ounce. To be fair, the food noise is horrendous so I’m having to have so much will power but I am not eating any different to when I was on MJ yet not losing. Weigh day isn’t until Monday though so maybe over the weekend but I doubt it, we’re away to the caravan as it’s September break for the school so with food noise and lots of fast food, I hope I can be good lol. I plan to be.

I have no gallstones and bloods okay, but after an endoscopy my stomach is extremely inflamed and they’ve taken samples. I already had acid reflux but when on MJ I did suffer 10x worse, must just have counteracted with it.
now I’ve got the all clear for gallstones. I’m going to pop back into pharmacy next week, my medication has been up from 1 to 4 tablets per day so maybe this could help? Who knows. I can only ask, I won’t do anything that’ll potentially make me unwell. But I’m hoping I get the ok to start again as it’s a great feeling seeing the scales coming down. I’ve went down a whole dress size in 4 weeks on MJ. Xx

Glad you are feeling a bit better, that must have been very stressful

Pumpernickelbrakes · 26/09/2025 23:01

Glad 4mg is going well so far @SkinnyOatFlatWhiteForMePlease

thsnks for the good advice/reassurance @LaGioiosanotLeviosa

@NeedSleepNow had very similar experience and glad to go up, 3.75mg definitely feels like it’s working and a good interim step instead of doubling the dose from 2.5 to’5

@Texanchilli sorry you’ve had issues with nausea. Would continuing to use 2.5mg doses work and extend your pen life? I think if you keep in the fridge always and wipe the pen tip with alcohol it should keep ok?

Wellfuckme · 27/09/2025 01:44

Weigh day for me today - wk 7
SW 18st 8lb
CW 17st 13lb
No loss this week but no gain either. Currently on 5mg pen. I tried upping my protein but just ended up with bad constipation which I didn't have before. I have also been really tired as well.

TheArtfulCrow · 27/09/2025 08:16

W9 D1, going up to 5mg now. Another 2lbs off this week. I am constipated but feel like things are starting to move a bit 🫣.

SW: 14st 10lbs
CW: 13st 4lbs
GW: 10st

GertieLawrence · 27/09/2025 08:35

Hi all, started the first 5mg dose yesterday after two months on the 2.5mg.

I’ve lost 16 pounds so far. Very pleased with that as I wanted the loss to be steady rather than drastic. Long way to go but it’s a good start.