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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

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March Starters 2025 Thread 7, where we are now all having advice from Janice, Janice can do one!

945 replies

TheSpoonyNavyReader · 16/08/2025 10:38

Welcome to thread 7.

Thank you for sticking around and making a little community of WL. This group makes me so happy that we are non judgmental and support each other.

OP posts:
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Tormundsbeard · 01/09/2025 21:40

Another one who hasn’t updated for ages, but has been following the threads.
SW 201lbs
CW 161lbs
GW 160lbs
so I have pretty much got there. I went up to 5 for a few months but came back down to 2.5 as the diarrhoea just didn’t stop on 5, and I also thought it would be better as I got near goal to get used to feeling a bit hungry, which I rarely did on 5.

I have gone from a size 18 to a size 12. I bought some size 14 on Vinted, but a lot of them look baggy.

What has helped me a lot is the effect on my blood sugar. One of the reasons I had gained weight is that if I left too long a gap between meals, it would trigger a migraine. Carb loading helps avoid a migraine coming on (for me), so I would end up inhaling loads of carbs on days when I was trying to eat less.

Now I can follow an intermittent fasting schedule, eating less carbs, lots of protein. I feel full, not hungry and get very few migraines.

I have 2 x 2.5 pens in the fridge, I may well keep on them for maintenance, we’ll see.

MJ has been such a positive experience for me.
well done and good luck to all the March starters.

GameOfJones · 01/09/2025 22:04

@Sloelydoesit sorry to hear about your bereavement 💐

northernlight20 · 02/09/2025 08:18

Got my 4st loss rosette on nutracheck this morning!! Beyond happy and grateful to mounjaro, life changing.

March Starters 2025 Thread 7, where we are now all having advice from Janice, Janice can do one!
MJ122025 · 02/09/2025 08:51

@SloelydoesitI'm sorry for your loss xx

@TheBossOfMe you're such an inspiration.

Stomach seems to have calmed.down now but am.going to look into the post MJ symptoms so see whether it could just be that..Combined with Laxido. I havent jabbed for 12 days now and weight has held steady. I have one dose left in a 7.5mg pen and was planning to split that. But I might push through another week..

Have just had a weekend of birthday celebrations and not weighed yet..but off today and planning the gym and a long walk.

Have a great day 😀

TheBossOfMe · 02/09/2025 14:07

@Sloelydoesit Very sorry for your loss, be kind to yourself <3

@northernlight20 Nice rosettes! Well done!

More odd symptoms as I titrate down, some of which were similar when I titrated up at the beginning of the journey. My period has gone on for days, which is annoying. I have PCOS and am 53 so probably perimenopausal, but it's interesting to me that this extended period also happened on the way up. Should probably go for a hormone check anyway. I had enjoyed not having any night sweats at all on a higher dose, but they're back with a vengeance now.

CFCmum · 02/09/2025 14:12

March starter here as well, not updated for a very long time.
just got back from a 10 day all inclusive holiday and put on 5lb but 4 days back and lost 4lb of that
sw 14.12
cw 11.1.4
gw 10:7

I’m also going be done soon! Currently taking 6.25 but I’m going to start to titrate down and just manage with what I have in the fridge. August has not been great for me as had two holidays so have only lost what I put on so feel a bit deflated but it’s better than gains! Spent half month on steroids though and have another 30 days on them due to an asthma flare up. They make me so hungry so hopefully the mj may neutralise that abit
well done on all the loses and it’s lovely to here those of you doing great going it alone

northernlight20 · 03/09/2025 07:50

Posting for my accountability. Weigh and jab day. Jabbed 12.5 today. And weighed in at 88.5kg
sw 114.4kg
cw 88.5kg
and I’ve finally settled on goal weight as 70kg

Aboutmeabouttime · 03/09/2025 09:09

Whoosh alert! After 5 weeks of no loss, scale says 3lb lost today! Hooray! Under 11st for first time in about 6 years, so so close to healthy BMI - like 0.2, so that is the next thing to see. Very pleased and best wishes to anyone else in a stall…

Bipaloss · 03/09/2025 09:32

northernlight20 · 03/09/2025 07:50

Posting for my accountability. Weigh and jab day. Jabbed 12.5 today. And weighed in at 88.5kg
sw 114.4kg
cw 88.5kg
and I’ve finally settled on goal weight as 70kg

Well done!

was this first or second dose of 12.5? Did my first 12.5 on Friday and hit me hard ! Headaches and sickness over weekend and nausea every time I eat still , first real dose with SE for me

northernlight20 · 03/09/2025 09:56

Bipaloss · 03/09/2025 09:32

Well done!

was this first or second dose of 12.5? Did my first 12.5 on Friday and hit me hard ! Headaches and sickness over weekend and nausea every time I eat still , first real dose with SE for me

First dose of 12.5, so far so good, don’t feel any different. Hope you feel better soon. Could you do 11 then go back to 12.5 after that?

Bipaloss · 03/09/2025 09:59

northernlight20 · 03/09/2025 09:56

First dose of 12.5, so far so good, don’t feel any different. Hope you feel better soon. Could you do 11 then go back to 12.5 after that?

🤞🏻 it works well for you

no, im sure it will be fine on 2.5 and 5mg I had low level se but only lasted for a week . And 12.5 is really boosting my weightloss so il continue (im still eating is just that morning sickness feeling now after I eat)

Illbefinejustbloodyfine · 03/09/2025 11:21

Hi all, have posted a seperate post but will ask here. I haven't jabbed for 3 weeks. Was on 7.5. Ready to start again but REALLY dont want to go down to 2 5. I niw have 2 pens (7.5 and 10) and they will be my last. No real serious side effects at any point.

What would you do? Might just got for 5. ....

Fairfaxandflavor · 03/09/2025 11:33

I've been splitting the 10 into five and I'll split my7.5 into 2.5 possibly less, but I see you haven't jabbed for a while so, maybe try a small dose first? See how you go, if OK go to five, I'm fine on that, only a few pounds to go, I'm actually under my goal but I'm keeping going so I've got a buffer.

GameOfJones · 03/09/2025 15:41

@Illbefinejustbloodyfine I would be tempted to go for a half dose of your 7.5 pen, so a 3.75mg perhaps and if fine go up to 5 next week.

I have decided this pen will be my last. It's a 5mg pen but I've titrated down to 3.75mg so I can hopefully get an extra week out of it.

Back into the 10s and (just) into a healthy BMI at 24.9 as I weighed 10st 13lbs this morning so 2lbs of my 3lbs holiday gain gone.

I actually reminded myself that at the start of the summer holidays my goal was to be 11st 2lbs by the time DDs went back to school as that would be 0.5lbs loss per week which felt realistic with holidays etc. So I've beaten that as their first day back at school was today.

Yetanotherusername2000 · 03/09/2025 18:10

I’m so worried about inflammation returning from my long covid. And all my menopause symptoms stopped. I really wanted to stay on it as long as I could but now I’m not sure 😔

museumum · 04/09/2025 09:24

I've just hit my 6 month anniversary!

Money spent on MJ = £1089
Weight lost = 12kg
NSVs = blood pressure moved from 'high-normal' to 'normal', joint pain largely gone, muscle cramps 90% improved. returned to slow running (never have been speedy).

No issue here with losing too fast that's for sure... but I had been gaining steadily since the covid/menopause storm hit me simultaneously so to reverse that is amazing.
Ideally I'd like to lose another 10kg but I'd be happy with 6kg and realistically another 3mo is about all I can afford at the new prices.

I am lifting heavy weights and getting stronger so I'm pretty confident I'm not losing muscle. I would really really like to shrink my boobs and waist which both ballooned in perimenopause. I'm currently a 14 in the hips, 16 in the waist and top end of an 18 in the bust, which I hate. It's not like I have a classic apple shape either as I'm quite muscular in the legs and arms. Sigh.

EDIT: I've stayed on 2.5 throughout to now but might go up to 5 next pen (especially if there's not much price difference).

seasidehunter · 04/09/2025 09:55

I am officially 6 months at the end of this week. Currently at 10st 6lb, so 2st 2lb lost. Less than half a stone to go, but would quite happily stay where I am.

I did a golden dose from my 5mg pen this week and probably got a bit more than 5mg... maybe just under 6mg. OMG... it feels like the very first week all over again. I don't want to eat anything, I feel sick, exhausted, and I'm freezing cold! Despite having a new 7.5mg pen in the fridge this has confirmed that I do NOT need to go up above 5mg. I'm happy to micro-dose and make the pen last a bit longer and then start titrating down.

museumum · 04/09/2025 10:01

museumum · 04/09/2025 09:24

I've just hit my 6 month anniversary!

Money spent on MJ = £1089
Weight lost = 12kg
NSVs = blood pressure moved from 'high-normal' to 'normal', joint pain largely gone, muscle cramps 90% improved. returned to slow running (never have been speedy).

No issue here with losing too fast that's for sure... but I had been gaining steadily since the covid/menopause storm hit me simultaneously so to reverse that is amazing.
Ideally I'd like to lose another 10kg but I'd be happy with 6kg and realistically another 3mo is about all I can afford at the new prices.

I am lifting heavy weights and getting stronger so I'm pretty confident I'm not losing muscle. I would really really like to shrink my boobs and waist which both ballooned in perimenopause. I'm currently a 14 in the hips, 16 in the waist and top end of an 18 in the bust, which I hate. It's not like I have a classic apple shape either as I'm quite muscular in the legs and arms. Sigh.

EDIT: I've stayed on 2.5 throughout to now but might go up to 5 next pen (especially if there's not much price difference).

Edited

Doh! I’m not in 2.5. I’ve been on 5 since week 3. So might go up to 7.5. Sorry for the confusion.

Illbefinejustbloodyfine · 04/09/2025 21:09

I decided on 5mg to get started again. Jabbed this evening, ive been putting it off not knowing what to do but didn't want to wait any longer. Hoping I won't have any ill effects.

TheBossOfMe · 05/09/2025 16:32

This isn't the most positive of stories, but I thought I'd share because it's a good lesson. A good friend spent at least a year on Wegovy, and shifted a really good amount of weight, going from a BMI of 32 to 22. She's been off it now for about 6 months, and I've only seen her once in that time, because life is busy. I saw her for dinner last night, and she was really down - she's put more than half of it back on in that 6 months, so is gaining at a significantly faster rate than she lost :(

We talked a lot last night about what's going wrong, and she's really clear (also kicking herself). She's always had a very carb heavy, sugar heavy diet - a real sweet tooth and used to eat really large portions of it. I think a lot of us have talked about needing to make significant lifestyle changes whilst on MJ - using the "space" MJ creates to re-train eating habits.

That's exactly what she didn't do. She relied really heavily on the food suppression to just eat less of what she used to, without any real lifestyle changes. Which is fine - someone said earlier that food isn't a moral choice, and that's true. What she's really struggled with is not over eating now that the food suppression has gone, and her portion sizes are back up to what they used to be, hence the weight gain. She's finding it hard not to crave that "full" feeling - whether it's delivered through WLIs or through large portion sizes. And never really added exercise in, so doesn't have that habit ingrained now.

Things she said wishes she'd done differently. Paid more attention to nutritional value of what she's eating and macros. Used the time to build an exercise routine that is now habitual. And really importantly - she went cold turkey rather than titrating down, which she now thinks was a mistake. She said it only took 4 weeks for any food suppression effect to wear off completely, and once that happened, she couldn't find a way to manage the desire for feeling, as she put it, "as stuffed as the Christmas Turkey". She thinks if she had titrated down, she might have had a better chance of slowly adjusting to not feeling like that.

So she's going to try and restart, either on Wegovy or MJ, not sure if anyone will accept her given it's been 6 months, but she'll give it a go. And focus on actual food composition and exercise in that time. I felt really sorry for her - she's not wealthy and this was a huge investment for her. I hope it goes better for her this time.

GiveMeWordGames · 05/09/2025 16:43

Oof, that's tough @TheBossOfMe , your poor friend. I hope she manages to get back on something to help her again. It is a cautionary tale, though.

Imissgoldengrahams · 05/09/2025 16:53

TheBossOfMe · 05/09/2025 16:32

This isn't the most positive of stories, but I thought I'd share because it's a good lesson. A good friend spent at least a year on Wegovy, and shifted a really good amount of weight, going from a BMI of 32 to 22. She's been off it now for about 6 months, and I've only seen her once in that time, because life is busy. I saw her for dinner last night, and she was really down - she's put more than half of it back on in that 6 months, so is gaining at a significantly faster rate than she lost :(

We talked a lot last night about what's going wrong, and she's really clear (also kicking herself). She's always had a very carb heavy, sugar heavy diet - a real sweet tooth and used to eat really large portions of it. I think a lot of us have talked about needing to make significant lifestyle changes whilst on MJ - using the "space" MJ creates to re-train eating habits.

That's exactly what she didn't do. She relied really heavily on the food suppression to just eat less of what she used to, without any real lifestyle changes. Which is fine - someone said earlier that food isn't a moral choice, and that's true. What she's really struggled with is not over eating now that the food suppression has gone, and her portion sizes are back up to what they used to be, hence the weight gain. She's finding it hard not to crave that "full" feeling - whether it's delivered through WLIs or through large portion sizes. And never really added exercise in, so doesn't have that habit ingrained now.

Things she said wishes she'd done differently. Paid more attention to nutritional value of what she's eating and macros. Used the time to build an exercise routine that is now habitual. And really importantly - she went cold turkey rather than titrating down, which she now thinks was a mistake. She said it only took 4 weeks for any food suppression effect to wear off completely, and once that happened, she couldn't find a way to manage the desire for feeling, as she put it, "as stuffed as the Christmas Turkey". She thinks if she had titrated down, she might have had a better chance of slowly adjusting to not feeling like that.

So she's going to try and restart, either on Wegovy or MJ, not sure if anyone will accept her given it's been 6 months, but she'll give it a go. And focus on actual food composition and exercise in that time. I felt really sorry for her - she's not wealthy and this was a huge investment for her. I hope it goes better for her this time.

What a shame on your friend
But I have never had any suppression and I think those chasing it/relying on it are in for a shock when they come off it.
I have a friend whose on 12.5, had no weight loss until this dose, no suppression but eats 3 course takeaway meals on a weekly basis.
I too think she will be in for a shock when she does stop
At some point we all need to make healthier habits and not rely on mj I guess

Fairfaxandflavor · 05/09/2025 17:26

@TheBossOfMe that's a really cautionary tale, thanks for sharing. I have changed my habits considerably, so that gives me some hope, and I will be titrating down, how sad for your friend, after all that effort, I do think I'll struggle with the exercise and the 'hollow' feeling I get when hungry, hopefully I'll satiate with healthy protein rather than anything else, we'll see in the next few weeks, Christmas is gonna be a bastard though.

popdepop · 05/09/2025 17:49

Hi all
not updated in a while
start weight 21.3.25 16 stone 11
current weight 13 stone 3 and in the overweight category from obese.
It really does feel like a long slog! 2 stone to go to be in a healthy bmi, then id like another stone off from there.
would never have done it without MJ. im going to try to afford to keep going to goal weight

northernlight20 · 05/09/2025 18:43

I’ve just realised it’s exactly 6months today I started mounjaro. As of today, I’ve lost 57.6lbs, I just can’t believe it, I also look very different and everyone has been mentioning it and complimenting. One major thing I’ve noticed is that people are definitely nicer to you when you aren’t as big. It’s been an eye opener and not sure I particularly like it.