Big price increases?

[CoverMeInMarmalade]

Anyone else seen this chatter about massive price increases announced for MJ (to pharmacies) in the last hour or so?

Very concerning as it looks like it could double the cost of some of the doses. I'll try to find the copy of the letter sent out...

Thank you. I'm going to try and do something similar. I'm still about half a stone from goal weight and was beginning to think I would never get there, even on 12.5mg. Pretty sure I won't now, but if I can make the three pens I have last as long as possible, I hopefully won't regain so quickly at least.

Most people don't qualify for it under the NHS but do qualify under prescribing guidelines. The NHS guidelines are much tighter because they can't afford to supply it to everyone who meets the prescribing guidelines.

I'm just hoping the NHS will be able to widen their criteria sooner rather than later @usedtobeaylis; and it will become more widely available. It will save them huge amounts in the long term not dealing with obesity related illnesses and all the issues and costs that are often lifelong.

Oh my god. I mistook your post and initially liked it because I thought you were being genuine in your appreciation of @LifeOfAShowGirl.

I didn’t realise you were being nasty!

I have 15 weeks of 15mg in the fridge & have ordered a few more pens from various places. Hopefully they will pull through & when I get them I will have to make a plan of what I am doing. Still have 4 stone to lose :( I don't want to go cold turkey so would look to titrate down.

Have sent you a DM

Medexpress have just sent an email confirming that Eli Lily are raising prices from 1st Sept.

So due to panic buying suppliers are already out of stock. This isn’t great for anyone who needs their next pen now is it. Just like toilet rolls during Covid.

She’s been exaggerating and scaremongering from the start of this thread. Coming on here in a bit of a panic it’s the last thing I wanted to read. Frankly she seems to be getting a buzz out of the drama, which I find distasteful. But your disapproval of my ironic post is noted. I’ve given myself a 👎

This really is going to create quite a storm. It's going to be interesting seeing how it finally settles and at which price points.

I can't see how lots of people are going to be able to continue - depending upon what pricing is finally implemented.

I'm only at 3.5 months in with a good 4 stone to go. It may well mean I stay on lower doses for affordability and take much longer. I can accept that just about as long as the price point isn't utterly ludicrous.

Yep have been with them nearly a year and am too close to goal to switch. So I'm screwed!

I’ve actually just researched what has happened and that this hasn’t come out of nowhere.

What is the most cost effective pen to uy and microdose on? Is it the 5mg pen - extracting x10mg of 2.5mg (which includes the bonus dose?).

I am feeling the panic to stockpile, but realistically I don't know where from or what doses or how much. I am half a stone from goal weight and was hoping to taper down soon. I have two and a half 15mg in the fridge.

I don't really want a stockpile though - what I want is the safety net I thought I had when I woke up this morning to reorder when I needed to.

I've been in tears. I feel such a fool for thinking I could be slim for any amount of time, and no doubt all the nay-sayers will be gloating now that we will revert to where we were.

She hasn’t done what you’ve said.

0–2 weeks after the last jab

• Drug levels fall: Tirzepatide’s half-life is ~5 days, so blood levels drop quickly; most of the effect washes out over ~3–4 weeks (4–5 half-lives).
• Hunger starts waking up: As pharmacologic appetite-suppression fades, people notice “food noise” returning—first as more frequent thoughts about food, then larger portions. Clinicians and obesity orgs explicitly note appetite comes back when you stop, especially if cessation is abrupt.

2–8 weeks

• Marked appetite rebound: Satiety gaps lengthen, cravings increase. (On-treatment, tirzepatide reduces energy intake and food reward signaling; remove the drug and those effects reverse.)
• Weight loss stalls → regain begins: Scales often stop trending down and creep upward. Early regain speed varies, but trials show stopping GLP-1s flips the curve toward regain compared with staying on therapy.
• Mood wobble is common: Some people report increased anxiety/low mood as hunger returns and weight control feels harder; overall evidence on GLP-1s and mental health is mixed (some improve, some worsen).

2–3 months

• Visible weight regain for many: In randomized “withdrawal” designs, people switched from active drug to placebo start gaining back a meaningful share of lost weight within a few months, while those who continue keep losing. (Semaglutide STEP-4: −7.9% more loss if continued vs +6.9% regain when stopped over the next year; the divergence starts early.)
• Quality-of-life starts to slip: In tirzepatide SURMOUNT-4, patient-reported outcomes (SF-36, IWQOL) improved with continued drug vs placebo—implying that those who stop see less improvement or deterioration as weight returns.

3–6 months

• Metabolic drift: Blood pressure, glucose, and lipids trend back toward baseline as weight returns (shown clearly after GLP-1 withdrawal).
• Psychological load: For some, the combo of renewed hunger, weight creep, and social stigma increases stress and low mood; others cope fine—studies show mixed mental-health effects overall.

6–12 months

• Substantial regain is typical if off-drug:
• Tirzepatide (SURMOUNT-4): After a ~21% loss during the lead-in, those switched to placebo regained ~14% across the following 52 weeks; those who stayed on drug kept losing.
• Semaglutide (STEP-4): Continued drug → further −7.9% loss; stopped → +6.9% regain from the randomization point.

12–24 months

• Many regain most of it if they don’t replace the medication with something: In the STEP-1 extension (semaglutide), participants regained ~2/3 of the weight they’d lost one year after stopping; cardiometabolic gains largely drifted back. (Tirzepatide data show the same direction of effect.)

This comes from Trump giving pharmaceutical companies 60 days to give Americans the same prices as their lowest priced countries or face federal action. He has allowed them to raise prices in other countries when achieving this.

@Gertieblue its okay. Things will work out and you will be slim, forever hopefully, this is just a wee bump in the road and things it will look differently a few weeks from now.

Starting with this rude and aggressive response, @Weepixie and going on to scaremonger.

The Wegovy patent will expire in 2032 and the Mounjaro in 2036, so hopefully the higher costs won't last a lifetime. I realise that's still a long time though for anyone who has been priced out.

@NeuroSpicyCat - are you on WLI? Or are you just loving (quite deliberately) being the prophet of doom and despondency today?

I don't think she's getting a buzz out of it. I think she's devastated, as am I.

But I do think she's inadvertently upsetting a lot of people who are already panicky and upset, myself included, and should probably dial it back a bit.

People need to stop panicking. There is no way that El Lilly is going to price a large percentage of its customer base out of the market. That would be commercial suicide.

Sorry if you can’t read the news and realise that what is happening is going to have a massive impact.

Most of their business is done in America. The drug is about to more than halve in price in America. They’ll be fine.