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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

May Starters Thread 3 ~ Onwards & Downwards!

1000 replies

SussexLass87 · 29/05/2025 21:05

Roll up, roll up...thread 3 for the loveliest bunch of losers!

"Onwards & Downwards" has become our little motto for the days when it all feels a bit tough and that wine / chocolate / cake looks a bit too bloody tempting.

Lots of love,
Lass x

OP posts:
Thread gallery
31
FlorenceNightshade · 17/06/2025 20:35

@Mounraine yes it should do because you’ve not used up all the clicks taking the full dose. You’ll just need an extra pen needle to free it!

Seahorsesplendour · 17/06/2025 20:48

Wow a really busy day!! Great to read everyone’s updates!

@ElsieJay good to hear from you & try & enjoy yourself ! You’ll have missed the shame part of the thread but I had a Bad weekend and had great advice about not letting it weigh me down (pun intended!!) and not getting stuck in that shame eat cycle this time! You’ve got this!! have fun!

Im moving up to 5mg after a couple of weeks of 3.3 then 3.75 I’ve been really hungry last couple of days! Maybe due to weekend shenanigans but either way have decided to go for it!!

onwards & downwards!!

DidILeaveTheGasOn · 17/06/2025 20:48

@sunshinesandringham I've had (still having actually) significant fatigue on 5mg, as well as acid reflux. It's actually put me off having a glass of wine this evening. I went for a walk instead. Back home for some gaviscon and water!

Seahorsesplendour · 17/06/2025 20:57

Mounraine · 16/06/2025 20:51

@Seahorsesplendour I've seen this kind of advice quite a few times regarding emotional eating

Hope you're feeling better OP doesn't sound like it can be the MJ if others have the same symptoms.

I fought against the MJ this weekend and overate and the scales went up nearly 2lb. I always do this just before I pass the next milestone. It's like I'm self-sabotaging. Grr. Decided fresh start today but a colleague bought me a chocolate bar mid afternoon and DP plated me up a massive portion of spaghetti bolognaise for my tea.

Thanks for this @Mounraine really helpful ❤

Mounraine · 17/06/2025 21:06

You're very welcome @Seahorsesplendour . Interestingly, I know that this journalling/awareness-raising approach is the way forward but I avoid it. I don't think I'm ready to face up to certain feelings :(

Im moving up to 5mg after a couple of weeks of 3.3 then 3.75 That's got me thinking I might do 3.3mg from a 5mg pen first.

Seahorsesplendour · 17/06/2025 21:26

@Mounraine the 3.3 was my golden dose! It did feel like a good step up from 2.5 to be fair but no real difference then when I went up to 3.75 but I’ve not struggled with SE which I know you have so might be worth a go! Good luck whatever you decide!!

Mounraine · 17/06/2025 21:35

Thank you for your thoughts. I was curious why 3.3mg and guessed it was because it was 6 equal doses from a 5mg pen(!). That means going a bit over the 30 days.

Samuraipizzacat · 17/06/2025 21:49

Quick question. I’m better to shift my jab day by a day than risk going up a level the day I’m going to a concert at the O2 right.

Im going up on wegovy from 0.25 to 0.5 and due to jab the same day as a massive show and dinner. Or is the first day usually ok?

hottubsundays · 17/06/2025 21:53

@sunshinesandringham reflux has been a huge thing for me since taking 5mg but I didn’t really compute what it was but since investing in an immense bottle of gaviscon everything is great!

Seahorsesplendour · 17/06/2025 21:56

That would have taken far more thought than I’m capable of right now!! 😅but does make total sense!!

I’ve added a screen shot of a Reddit post I found about the 30 days it made me decide I would be comfortable taking the risk but obviously it’s up to each individual to decide!! just felt like a sensible way of looking at it.

May Starters Thread 3 ~ Onwards & Downwards!
HereIGoOnceMore · 17/06/2025 22:54

I’ve been watching this thread as a cautious newbie (2 weeks & 5 days in) and am grateful to everyone who has shared their experiences as it has given me the courage to take the plunge.

I wanted to comment about the Reddit screenshot above. Whilst it’s true that the risk of introducing pathogens increases each time the rubber seal is punctured (less so if you use an alcohol wipe and wait 30 seconds for it to dry before introducing the needle each time), it is false to say that the medicine will degrade after 30 days.

The 30 days represents the time it has been tested as safe out of the fridge in addition to the manufacturing time. There will be also a buffer for safety which is often a few days beyond the time advised.

DidILeaveTheGasOn · 18/06/2025 06:30

@samuraipizzacat I had similar questions when I went to see Sam Fender. In the end, I jabbed in the morning before we left. I don't think side effects kick in that much on the first day - the only thing that gets me every time I jab is the sleeplessness that night, so it would be quite well suited to a night out!

DidILeaveTheGasOn · 18/06/2025 06:42

Not sure if it's the Mj or antihistamines I'm taking for hayfever, but I'm having some really awful dreams. I just dreamt that I'd done something stupid but harmless and my partner finally reached his limit and asked me to leave.

On Monday night, I dreamt that it had been decided I wasn't allowed near my children anymore. My ex husband and my partner were in agreement!

They've been terribly gut-wrenching dreams. At least after today's, one of our most affectionate cats came and curled up into my side and purred. Thank goodness for cats.

Seahorsesplendour · 18/06/2025 07:12

@HereIGoOnceMore i read the Reddit post as saying exactly what you just said so it’s good that someone else agrees!! Welcome to the thread! 😊

@DidILeaveTheGasOn they do sound like horrid dreams!! hope you’ve managed to shake them off!! Nothing worse than when that dread feeling lingers!!

First 5mg jab done!

can’t believe I’m in week 7 already!!

hope everyone has a good day!!

GoldieLookingBoots · 18/06/2025 07:41

Morning everyone! Hope you’re all staying hydrated in the heat!
I’ve just checked my weight as it’s the end of week 5 for me. I’m another 4lb down this week. Tbh I don’t think I’ve been eating enough so I probably need to go for calorie counting as it’s a long journey and I’ve felt no appetite this week. I jabbed 3.75 last week and I think I’ll do the same tonight. I ordered some electrolytes as I was getting muscle twinges in my calves - a precursor to cramps despite being hydrated. I’m hoping g they’ll help with feeling foggy too! That might just be perimenopause though.

SW: 17 st 7
CW: 16 st 4.5

Mounraine · 18/06/2025 07:47

Thank you for the thoughts about going beyond the 30 days. I think I'm going to try the six doses next month.

@DidILeaveTheGasOn I had a dream about Jimmy Savile last night :( The dreams are a low key side effect for me, but quite draining.

Daily weigher here, and saw a shift downwards this morning, so feeling good. So good that I've moisturised my full body after my shower and decided to wear a white top for work.

MyScaredCat · 18/06/2025 07:54

It’s a 1lb loss this week which I’m taking as a massive win.
7 weeks and I’ve lost 21.5lbs.
ive definitely struggled to feel the mj effect the last 2 weeks so decided to up my dose.
Ive been on 2.5 the whole time.

ive 2 doses left in my pen so today im going to take 90 clicks (3.75) and next week take the remaining 30 clicks plus the ‘golden dose’

then I’m going to order a 5mg pen. Hopefully to stick with 3.75, but I’ll see how I get on

Fatrosrhun · 18/06/2025 09:04

I took the golden dose last night. There was loads left so I decided to take 4mg. Haven’t had any side effects yet. We’ll see how the suppression is. On 2.5 I’d say I had 25% suppression that others seem to have.
There is still quite a lot of MJ left in the pen after the golden dose. My husband (who does my injection) thinks well over 3mg. So I’m wondering about trying a second golden dose next week? The pen has always been kept in the fridge. It would obviously be over a month.

MyScaredCat · 18/06/2025 09:10

Fatrosrhun · 18/06/2025 09:04

I took the golden dose last night. There was loads left so I decided to take 4mg. Haven’t had any side effects yet. We’ll see how the suppression is. On 2.5 I’d say I had 25% suppression that others seem to have.
There is still quite a lot of MJ left in the pen after the golden dose. My husband (who does my injection) thinks well over 3mg. So I’m wondering about trying a second golden dose next week? The pen has always been kept in the fridge. It would obviously be over a month.

Are you sure you didn’t miss one of your 4 doses? I did the golden dose last pen and took 2.5. I wouldn’t have said there was loads left

Fatrosrhun · 18/06/2025 09:24

I don’t think so. Although I didn’t do the injection, my husband did, but I definitely felt the injection and he counted to five. There was never any liquid on me. And he’s used to doing injections on our horses.

MsTamborineMan · 18/06/2025 10:29

How's everyone coping with fatigue? I've been absolutely exhausted this last couple weeks, like falling asleep at work exhausted

Also anyone stayed on 2.5mg? How was your suppression month 2? I've had reasonable suppression these last few weeks, it's slightly faded by week 4 but I'm worried if I increase I'll get worsened fatigue and not sure it's really necessary. I had a lot of nausea and appetite loss initially which has now settled so I'm worried that'll be worse again on 5mg, but I'm also worried if I stay on 2.5mg I'll waste money if the affects start to taper off.

Thinking of maybe upping to 3.75mg by counting clicks?

Moneyordream · 18/06/2025 10:58

Today i fitted into a size 16 dress, I normally buy a size 20. I am feeling so much happier in myself with what im doing. In 6 weeks I have lost a stone and a half

AccidentalPrawnYouFool · 18/06/2025 11:13

Moneyordream · 18/06/2025 10:58

Today i fitted into a size 16 dress, I normally buy a size 20. I am feeling so much happier in myself with what im doing. In 6 weeks I have lost a stone and a half

That is amazing! Well done, what an achievement 👏🏻

Iggy35 · 18/06/2025 11:19

@Fatrosrhun it does sound like you had 3x weeks of your dose of 2.5mg and then you took little extra for your 4th 2.5 & hence you would still have a little left from the golden dose
Normally the pen would have
2.5mg (0.6ml)
2.5mg (0.6ml)
2.5mg (0.6ml)
2.5mg (0.6ml)

  • Golden between 0.6 to 0.9ml (so another 2.5 - 3.75mg) - this can somewhat vary but just a typical example.

I've not heard of anyone getting 6 full doses out of their pen (and I read through 1000s of posts in this forum)

Fatrosrhun · 18/06/2025 11:30

Yes it’s strange. But the pen has been “used” each week, set up, primed and administered. I’ve felt it in my leg and there hasn’t been any spillage. And my husband has lots of experience doing injections. I wonder if I got a lucky pen! You’d think I’d have been able to notice a difference in food noise/lack of suppression if I’d missed a dose. But I haven’t had a huge amount of affect from the 2.5 pen all month. I also haven’t had any change in sensation from the 4 I took last night either.

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