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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Mounjaro DECEMBER Starters Thread 3

819 replies

Slimwannabe · 03/05/2025 10:27

Just starting up a new thread!

OP posts:
MaybeMrs · 24/06/2025 11:35

LC4life · 20/06/2025 22:20

Hello @everyone and apologies for the long silence!

Life completely took over with work, family and a few other ongoing issues, then prepping for a family holiday... I’ve caught up on the posts I’ve missed and I’ve loved reading everyone’s updates, NSVs and the amazing support we all share as part of the December 2024 starters group.

I have had a few NSVs myself recently:

  • I can now get out of the car driver’s seat using just the strength in my legs, no more pushing up with my arms!
  • On holiday, the seatbelt had a bit of room left, and for the first time in a long time, I didn’t feel awkward sitting next to a stranger.
  • I’m giving away clothes that are now too big (especially trousers) and rediscovering old favourites from years ago. I’ve only bought a couple of new jeggings but for now, I’m enjoying the nostalgia. If you see someone walking to work looking like it’s 2003, that’ll be me! 😂
  • My knee pain has almost completely gone, and I’ve also come off prescribed PPIs (omeprazole) after years of being on them daily. I only need one maybe every couple of weeks now, and I honestly think long-term use contributed to a lot of my issues.

@TrinityWaves and @mrsmaybe — hello fellow MJ triplets! I’m also now squeezing into my favourite size 14 jeggings, though I’m mostly wearing 16s. I’m 5’8” (used to be 5’9”, but gravity and weight caught up with me 😅). I always used to be the tall/giant one out of my friends, but lately I’ve felt short compared to so many younger really tall women — anyone else noticed that?

@shrinkingfi when I lost a lot of weight in the early 2000s, I had noticeable hair loss too. My hair’s always been on the finer side, so I’m being extra careful now. I take several supplements that help, including marine collagen, zinc picolinate, vitamin D, B12, biotin, and omega-3s. I also use inositol for PCOS, which may help with hormonal hair loss too. If you’ve got bloods coming up, it’s worth asking your GP to check ferritin (aim for >70 for hair), vitamin D, B12/folate, zinc, and thyroid function (TSH + ideally FT3/FT4).

@WittyLimeBiscuit so sorry to hear about the kidney stones. I’ve had quite a history with them myself, multiple stents, laser surgeries and an episode of sepsis. Luckily nothing serious in recent years (touch wood). I completely get the challenge with oxalates as trying to balance healthy eating with stone prevention isn’t easy. Wishing you a smooth recovery!

I am currently week 29, on 9mg.

After 28 weeks

• Height: 5’8” (173 cm)
• Starting Weight (SW): 260lbs (18st 8lbs / 118kg), BMI 40.3
• Current Weight (CW): 207.4lbs (14st 11.4lbs / 94.1kg), BMI 31.5
• Total Loss in 28 Weeks: -52.6lbs (-23.9kg), of which 55.5% fat loss and 44.5% lean mass loss

• Weeks 1–4: -12.0 lbs (-5.5 kg), of which fat loss: 6 lbs (50%) and lean mass loss: 6 lbs (50%)

• Weeks 5–8: -7.6 lbs (-3.4 kg), of which fat loss: 3.3 lbs (43%) and lean mass loss: 4.3 lbs (57%)

• Weeks 9–12: -8.2 lbs (-3.7 kg), of which fat loss: 5.0 lbs (61%) and lean mass loss: 3.2 lbs (39%)

• Weeks 13–16: -7.4 lbs (-3.4 kg), of which fat loss: 4.7 lbs (60%) and lean mass loss: 3.1 lbs (40%)

• Weeks 17–20: -8.6 lbs (-3.9 kg), of which fat loss: 5.2 lbs (60%) and lean mass loss: 3.4 lbs (40%)

• Weeks 21-24: -5.4 lbs (-2.4 kg), of which fat loss: 3.4 lbs (63%) and lean mass loss: 2 lbs (37%)

• Weeks 25-28: -3.0lbs (-1.36kg), of which fat loss: 1.7lbs (56.7%) and lean mass loss: 1.3 lbs (43.3%) – all-inclusive holiday in that period where I gained 4.6lbs in 9 days despite eating fairly healthy, but much more compared to what i eat at home.

Edited

Well done on your NSV's!! Wooooop!

I'm slow and steady at the moment, although its still coming off. I'm on 15mgs now but its kicking my ass a bit so i'm going to reduce back to 12.5mgs on the next jab.

SW : 18st 9.5lbs
CW : 13st 8lbs
Total loss so far 5st 1.5lbs

frogpigdonkey · 25/06/2025 20:07

It’s so great to see all the losses and NSVs here. Mounjaro has been an absolute game changer for me and so has this group- you’ve helped me through the challenging days and to trust the process through slow days and I’m very grateful. Still got a long way to go but I’m more confident than I have ever felt that I will get there.

i had a lovely NSV yesterday- I went shopping - bought some 16s and a cheeky 14 and even better, saw one of the super pretty bras in M&S and they had one that fit! Clothes have been such a fraught thing for me all my life- couldn’t fit in Miss Selfridge or top shop as a teen even and clothes shopping has always been about places I could buy stuff that fit me not the cool stuff. I’m still at the upper end but just being able to go into a shop and be confident I can find something I can at least try on is a big deal for me. Just to go shopping without wondering if I’ll be able to find anything to fit my fat arse is a big win!

ShrankLastWinter · 25/06/2025 22:11

@frogpigdonkey so much this! The other day I even bought some clothes in fancy shops at an airport. I suddenly realized that of course they would probably have my size and they did

frogpigdonkey · 25/06/2025 22:44

@ShrankLastWinteri have an ostentatious Gucci belt I bought in an airport over 10 years ago because my excitement that I fit into it exceeded all my budget rules. I’ve never fit into it since but I’m tantalisingly close now! It’s such a delight. I try not to be too shallow but being able to wear things without ‘can I fit’ or ‘do I look like a hippo’ being the prime consideration hs been a huge motivation on this journey. Still can’t really see me slim, but feel like Im getting there. So glad you are enjoying this part of the journey too!

LC4life · 26/06/2025 14:27

It was WoW (Weigh-in Wednesday from @TrinityWaves) yesterday and I’m really happy with a 3lb loss this week! 🎉

Especially because I’ve not been counting calories, just following a really healthy, liver-friendly, high-protein meal plan I created for myself with the help of AI 😂. It’s been period week too!

I’m now working towards my triple milestone goals, getting under:

  • 200lbs
  • 90kg, and
  • BMI 30!

They’re all getting really close now, which feels both exciting and a bit surreal.

However I’ve started having some right kidney pain again, mainly overnight and first thing in the morning. I suspect it's because of dehydration as I've been drinking too much coffee and not enough water. Also, possibly overdoing it with baby spinach salads and chia seeds, great for the liver but both high in oxalates, which aren’t great for kidney stones. So I’ve adjusted my food plan this week to cut back on moderate and high-oxalate foods and am reminding myself to actually drink proper water, not just coffees. Hopefully that’ll help.

I’ve also got liver blood tests coming up next week to check on my raised liver enzymes again, so fingers crossed the changes I’ve made recently will show some improvements! 🤞

Last night I only injected 5mg Mounjaro (instead of 9mg) in case it does raise my liver enzymes. Hopefully that will also help, and hopefully I won't be too hungry this coming week.

After 29 weeks
• Height: 5’8” (173 cm)
Starting Weight (SW): 260lbs (18st 8lbs / 118kg), BMI 40.3
Current Weight (CW): 204.4lbs (14st 8.4lbs / 92.7kg), BMI 31
Total Loss in 29 Weeks: -55.6lbs (-25.2kg), of which 56.3% fat loss and 43.7% lean mass l
oss

W29 only: -3lbs (-1.36kg) to 204.4lbs
Dose: 9mg, upper right belly, Not tracking calories, following a liver-friendly, high-protein meal plan, period week

LC4life · 26/06/2025 14:38

TrinityWaves · 22/06/2025 21:48

Rest your arm on their head - that's what I do 😄
We're MJ twinning a lot then as same clothing size and BMI is the same too.
I'm hoping to be a size 12 ish at goal. I better be as I've got a few bits in this size already as motivators 😂

I think I'd love being a size 10-12 at goal, but mainly look slender and muscly with not too much loose skin🤞🏼

LC4life · 26/06/2025 14:40

Lindy0070 · 22/06/2025 20:51

Evening all, it’s been a couple of weeks since I’ve checked in. Latest stats are as follows:

Jab 29 10mg
SW 213lbs
CW 184.8lbs
TW 161lbs

Total lost: 28.2 pounds!!

So I’m over halfway and smashed through the 2 stone barrier at last!!! 23 pounds or thereabouts to go.
I’ve been busy this weekend altering some work clothes. I’m a seamstress anyway so I begrudge buying new if I can help it. Also, when your husband says your arse looks like a sack of spuds in a pair of trousers, that’s the push I needed to sort them out 😂😂. Honestly, I took 2 inches from the crotch area to get rid of the saggy bottom and I still had to take in an inch down the side seams. NSV 🙌🏻🙌🏻.
I've been reading comments from a number of you that have similar health issues to me. I’ve been taking 5mg Ramipril for a few years now for high blood pressure. I’m not due an annual check up for a few months but was wondering if I should book an appointment to have a check. I’ve also not seen any doctor since I’ve started on MJ 👀. I’m hoping that I can reduce the dosage at least 🤔
I’ve mentioned this before but I have very fine hair and I’ve been taking Biotin for a few months now and I’ve also started washing my hair with Routine Wellness anti-thinning shampoo. I’ve definitely noticed I’ve got more “new” baby hair coming through which is more wispy. Thin hair is hereditary on my mother’s side so any help is great!!
Have a great week everyone, you’re all doing amazing 🙌🏻🙌🏻🎉😁

You could get a lot of business from all of us adjusting our favourite clothes! 😂

JunoRoma · 26/06/2025 19:38

Slightly weird NSV today. I was shaving my legs and realised that my calf muscles are visible when flexed! Checked my arms and it's the same with my biceps (my triceps are obscured by my impressive bingo wings).

Goinghome25 · 27/06/2025 08:47

Morning Everyone.

Week 30! How did this happen!? I sts this week but with only 7lbs to go it will be slow now...

Ive been getting the holiday clothes ready and everything is too big! Im 7lbs down since Easter, and as I have now lost 2 cup sizes my bikinis look ridiculous and are falling off me! My underwear suddenly looks huge

Im off to H&M today for some cheap pants...and I may try on shorts!

I also need cup size swimwear which is £££ so will just buy one for now. My Molke bras arr still ok but the underwired ones need to go..

Anyone else struggling to know what to wear? .... i had nailed covering the chub and now its not there it just feels so alien!

shrinkingfi · 27/06/2025 08:55

Good morning all! I’m wondering if there is anyone in our group on HRT? Will try to keep it brief…My GP is very sweet but has no experience of MJ and certainly no lived experience of the joy that is menopause! I’m on a patch for oestrogen and oral progesterone. Had issues with bleeding which the consultatant said was due to insufficient progesterone and told me to double the dose. GP has refused to change my prescription so I’ve been buying a pack privately (£££) a month to supplement! Voy say that because MJ affects the absorption of oral meds, this could be the problem and offered to pause my treatment 😱😱😱😱. Not tempting! I hear there is a combined patch available, but has anyone else experienced this and how did you address it? Thanks - and also thanks for my daily little bit of support on this group, just knowing you’re not alone with the ups and downs helps so much!

MerryChristmasYaFilthyAnimals · 27/06/2025 09:20

Oooh not official weight day! But hit 11st 9lb this morning. So finally at 3 stone.

I ordered my next pen from MedExpress and was thinking about my target weight of 9st 9lb and put that in as my actual weight. FFS. So I look like I've lost 2.5 stone in 6 weeks. I've emailed them as asked them to adjust my recorded weight and sent a pic of my scales with proper weight. Doh!

Goinghome25 · 27/06/2025 13:15

shrinkingfi · 27/06/2025 08:55

Good morning all! I’m wondering if there is anyone in our group on HRT? Will try to keep it brief…My GP is very sweet but has no experience of MJ and certainly no lived experience of the joy that is menopause! I’m on a patch for oestrogen and oral progesterone. Had issues with bleeding which the consultatant said was due to insufficient progesterone and told me to double the dose. GP has refused to change my prescription so I’ve been buying a pack privately (£££) a month to supplement! Voy say that because MJ affects the absorption of oral meds, this could be the problem and offered to pause my treatment 😱😱😱😱. Not tempting! I hear there is a combined patch available, but has anyone else experienced this and how did you address it? Thanks - and also thanks for my daily little bit of support on this group, just knowing you’re not alone with the ups and downs helps so much!

I came off HRT a month after starting Mounjaro. I found straight away MJ levelled my hormones and all peri symptoms had stopped.

Still got Mirena but I stopped taking Oestrogel.

I had a small bleed last month for the first time in 18 months. I requested to see a female GP as I am 57 so its a red flag if youre post meno.i told her about MJ and my weight loss and lack of hot flushes sore boobs, brain fog etc

She asked if I had ever had blood tests done to verify Im menopausal. No I have not.

So she organised some...they came back showing I am not post menopausal!!!

Goinghome25 · 27/06/2025 14:05

MerryChristmasYaFilthyAnimals · 27/06/2025 09:20

Oooh not official weight day! But hit 11st 9lb this morning. So finally at 3 stone.

I ordered my next pen from MedExpress and was thinking about my target weight of 9st 9lb and put that in as my actual weight. FFS. So I look like I've lost 2.5 stone in 6 weeks. I've emailed them as asked them to adjust my recorded weight and sent a pic of my scales with proper weight. Doh!

Well done on reaching your 3 stone milestone!!

ShrankLastWinter · 28/06/2025 08:50

Great to read the updates and everyone sounding so positive! Congratulations on the scale and non-scale victories!

My curve was almost flat for about 3 weeks, then suddenly 0.9kg disappeared last night 🤷‍♀️.

I think it’s because I have a sort of period, - breakthrough bleeding on my progesterone pill. Weight suddenly drops each time this starts.

I didn’t have any bleeding for years, but do sometimes now on MJ. There was the warning to use extra contraception when going up a dose, but I’ve been on 7.5mg for ages, so it’s not just slow gastric uptake as that message suggested. Lots of women seem to report revived periods, so I wonder what the relationship between all these hormones actually is. Especially as MJ seems to help so many women with PCOS.

SW 103.6 kg (BMI 35.?, 172cm or nearly 5’8”)
CW 75.3 (BMI 25.5)
GW 73.6 (BMI 24.8)

I can’t begin to describe how much I’m enjoying being not-fat. It’s just miraculous.

Reckon I’m going to try to get down to my ultimate goal of 30kg off and just under BMI 25, then maintain under 75kg. I’ve bought lot of new (secondhand) clothes in size M or smallish 14 and am very happy in them.

Have a lovely lighter weekend all!

ShrankLastWinter · 28/06/2025 09:28

Also, my scales say that only a bit more than 4kg of the 28.3kg I’ve lost is muscle rather than fat, so I’m pretty pleased with that and a strong advocate of high protein plus exercise!

Goinghome25 · 28/06/2025 10:43

shrinkingfi · 27/06/2025 08:55

Good morning all! I’m wondering if there is anyone in our group on HRT? Will try to keep it brief…My GP is very sweet but has no experience of MJ and certainly no lived experience of the joy that is menopause! I’m on a patch for oestrogen and oral progesterone. Had issues with bleeding which the consultatant said was due to insufficient progesterone and told me to double the dose. GP has refused to change my prescription so I’ve been buying a pack privately (£££) a month to supplement! Voy say that because MJ affects the absorption of oral meds, this could be the problem and offered to pause my treatment 😱😱😱😱. Not tempting! I hear there is a combined patch available, but has anyone else experienced this and how did you address it? Thanks - and also thanks for my daily little bit of support on this group, just knowing you’re not alone with the ups and downs helps so much!

Have you been offered Mirena for the progesterone element of hrt? It doesnt suit everyone but I love mine (and I was really resistant to getting it )

Goinghome25 · 28/06/2025 10:46

ShrankLastWinter · 28/06/2025 08:50

Great to read the updates and everyone sounding so positive! Congratulations on the scale and non-scale victories!

My curve was almost flat for about 3 weeks, then suddenly 0.9kg disappeared last night 🤷‍♀️.

I think it’s because I have a sort of period, - breakthrough bleeding on my progesterone pill. Weight suddenly drops each time this starts.

I didn’t have any bleeding for years, but do sometimes now on MJ. There was the warning to use extra contraception when going up a dose, but I’ve been on 7.5mg for ages, so it’s not just slow gastric uptake as that message suggested. Lots of women seem to report revived periods, so I wonder what the relationship between all these hormones actually is. Especially as MJ seems to help so many women with PCOS.

SW 103.6 kg (BMI 35.?, 172cm or nearly 5’8”)
CW 75.3 (BMI 25.5)
GW 73.6 (BMI 24.8)

I can’t begin to describe how much I’m enjoying being not-fat. It’s just miraculous.

Reckon I’m going to try to get down to my ultimate goal of 30kg off and just under BMI 25, then maintain under 75kg. I’ve bought lot of new (secondhand) clothes in size M or smallish 14 and am very happy in them.

Have a lovely lighter weekend all!

I tried on loads of clothes yesterday.
Before MJ I was a size 16.
Now...

Size 12 fits loosly and in H&M...

Small!

🥳🥳🥳

ShrankLastWinter · 28/06/2025 11:50

@Goinghome25 small!! Crazy!!!

I reckon I’m happy with 14/M. Sometimes it’s loose around my middle but my shoulders are the limiting factor, so I’m ok with that. Some neat fitting dresses are still L/16, although I’m not really even overweight anymore!

Goinghome25 · 28/06/2025 12:58

ShrankLastWinter · 28/06/2025 11:50

@Goinghome25 small!! Crazy!!!

I reckon I’m happy with 14/M. Sometimes it’s loose around my middle but my shoulders are the limiting factor, so I’m ok with that. Some neat fitting dresses are still L/16, although I’m not really even overweight anymore!

You must be taller than me though?

Im 5ft4.

Having S on a label of something I am wearing is blowing my mind!

ShrankLastWinter · 28/06/2025 15:27

Yes, I’m 3.5 inches taller and big with it, size 7.5 feet.

So incredibly nice being able to buy clothes in any shop! I could go on holiday and forget my cossie or beach dress and just… buy one. Mind blown.

CountryVic · 29/06/2025 02:29

I just went up to 5mg. Took it Friday at 5pm, ate tea and wished I haven’t, not really eaten since and it’s now Sunday lunch. I’ve been keeping up with the fluids, had a coffee and some crackers.
Terrible headache last night and a stomach ache, but hoping the worst is over. I was on 2.5 for 4 months then put myself onto 3.75 for 3 months, and now gone up. Lost 17 kilos all up, I plateaued and was ok with that as inflammation down, but hunger pains were coming back. Onwards and up to us all!

Slimwannabe · 29/06/2025 11:25

3lb off this week, which drops me into the next stone bracket and also means that I've lost more than 50lbs so far, which are lovely milestones!

SW: 273lb
CW: 222.5lb

To jump on the period bandwagon, I've had extremely heavy, painful, and long periods since they first started. Since MJ my periods have been relatively normal - no more flooding or changing a tampon every 30 mins, and they only last a week. I am delighted! Sorry for those of you that have seen disruption though!

OP posts:
JunoRoma · 29/06/2025 11:50

@Slimwannabe - 50lb down is great!

JunoRoma · 29/06/2025 11:55

@CountryVic I also moved up very slowly. I'm now tolerating 5mg. I'm taking it on Monday evenings and at the moment suppression is quite strong for the first 3 days, but by the weekend I have some appetite and am able to enjoy my food.

frogpigdonkey · 30/06/2025 13:40

Week 30
SW 15 stone
CW 12 stone
TW 9 stone
total loss 42 pounds!

finally made it! 20% of start weight, a lovely round 3 stone gone! Huzzah and hurrah I’m half way there! @MerryChristmasYaFilthyAnimalsstill twinning 😁😁 might have a burger to celebrate!

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