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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2025 Starters Thread 3

1000 replies

TheSpoonyNavyReader · 02/04/2025 12:47

New thread as I am sure we will fill thread 2 up by the end of today!

Welcome back everyone and well done for all the losses. Some have 5-6 stone to lose, some have 2 stone and me I have put 4 stone but looking at the BMI chart I could lose 6 stone and still be in the healthy range.

OP posts:
Thread gallery
23
TheBossOfMe · 09/04/2025 10:54

6 days after my first 5mg jab, and I'm definitely feeling suppression wearing off today, I'm actually hungry for the first time since my last jab, so today is going to need willpower to get through!

The NSVs are keeping me going - I managed a non-stop run this morning without having to stop for a few minutes because I was puffed out or something was hurting - I haven't been able to do that in a while.

And I've lost almost two inches off my waist measurement. That's huge for me, the hardest place for me to shift weight, and where I carry all of my excess weight (such a problem for health).

Plus - and this is another huge one, I think I may have stopped snoring. I wear a sleep tracker because my sleep is poor - my deep sleep has hugely improved, so has my REM, and my wake up periods diminished. But it also shows an enormous improvement in breathing regularity - I might turn on the snore tracker tonight and see what it says (DP isn't here this week, so I can't ask him!)

EchoNova · 09/04/2025 11:08

TheBossOfMe · 09/04/2025 10:54

6 days after my first 5mg jab, and I'm definitely feeling suppression wearing off today, I'm actually hungry for the first time since my last jab, so today is going to need willpower to get through!

The NSVs are keeping me going - I managed a non-stop run this morning without having to stop for a few minutes because I was puffed out or something was hurting - I haven't been able to do that in a while.

And I've lost almost two inches off my waist measurement. That's huge for me, the hardest place for me to shift weight, and where I carry all of my excess weight (such a problem for health).

Plus - and this is another huge one, I think I may have stopped snoring. I wear a sleep tracker because my sleep is poor - my deep sleep has hugely improved, so has my REM, and my wake up periods diminished. But it also shows an enormous improvement in breathing regularity - I might turn on the snore tracker tonight and see what it says (DP isn't here this week, so I can't ask him!)

Snoring has stopped for me too - I used to snore every night and DH would oftern have to move to the spare room. I'm on week 5 now and I haven't snored since Week 1. So it's a win win for both of us!

Fatmumslim01 · 09/04/2025 12:39

Had a cheeky early weigh today and I've lost another 2 pound! And am I to the next stone bracket at 13-13! So that's 8 pound in 3.5 weeks I think?

BVsMum · 09/04/2025 12:41

popdepop · 06/04/2025 06:35

Morning
W3D3 and I'm not really feeling the effects of 2.5mg anymore. I have ordered 5mg pen hoping it kicks back in again. I know the 2.5mg is supposed to be for your first month, but has anyone used the golden dose to inject 2 x 2.5mg on their 4th injection to move up? inject at the same time. That way not wasting the golden dose and less of a faff?

What is the golden dose?

MamaBanana12 · 09/04/2025 12:49

wow I had good suppression on 2.5mg, moved to 5mg on Monday and I havnt eaten in 2 days - nausea is not too bad but every bit of food disgusts me!!
im sat in front of a chicken salad wrap and ive eaten 5 prunes (constipation fun)

weighed in again though and have lost 19lbs since 3rd march but I just need to start eating! But I have no interest.

I do intermittent fasting normally. So don’t start eating til 12pm anyway but I didn’t have anything yesterday and I’m still not fussed now

TheBossOfMe · 09/04/2025 13:00

BVsMum · 09/04/2025 12:41

What is the golden dose?

There’s an extra dose in the pen so 5 doses not 4. You can get it out with a syringe to get an extra week from it. Or do what @popdepop is thinking about doing and double dosing to move up strength a week early (not recommended but a lot of people do that if they aren’t experiencing any significant side effects).

Fatmumslim01 · 09/04/2025 13:30

Fatmumslim01 · 09/04/2025 12:39

Had a cheeky early weigh today and I've lost another 2 pound! And am I to the next stone bracket at 13-13! So that's 8 pound in 3.5 weeks I think?

Just realised it's 2.5 weeks not 3.5 so 8 pound off in 2.5 weeks! 3 pound then 3 then 2

GameOfJones · 09/04/2025 14:38

@Loveab123 that sounds like the right decision to stop if it is making you feel low. You aren't the only one to feel that, I've read a lot about Mounjaro potentially worsening symptoms of depression etc. It is very strange how everyone reacts so differently to it and you just have to make a decision based on your personal circumstances and how you are feeling in yourself.

Bipaloss · 09/04/2025 15:22

MamaBanana12 · 09/04/2025 12:49

wow I had good suppression on 2.5mg, moved to 5mg on Monday and I havnt eaten in 2 days - nausea is not too bad but every bit of food disgusts me!!
im sat in front of a chicken salad wrap and ive eaten 5 prunes (constipation fun)

weighed in again though and have lost 19lbs since 3rd march but I just need to start eating! But I have no interest.

I do intermittent fasting normally. So don’t start eating til 12pm anyway but I didn’t have anything yesterday and I’m still not fussed now

I’m with you , took jab Sunday (not full dose as had some leakage)

Monday ate a babybel all day
Tuesday protein shake , chicken piece and a spoon of coal Shaw (only lunch no dinner)

today protein shake , 1 egg scramble egg 1 slice salmon 4 dates , ate half of it and stuffed

able to drink loads of water

the suppression is unreal but I do feel a bit of hunger today just can’t eat much. no SE but TOM arrived today and the cramps is strongest I had since I was a teen hopefully it last the normal 1-2 days (lasted 3 last month on w1 of 2.5 mg)

seasidehunter · 09/04/2025 15:40

Bipaloss · 09/04/2025 15:22

I’m with you , took jab Sunday (not full dose as had some leakage)

Monday ate a babybel all day
Tuesday protein shake , chicken piece and a spoon of coal Shaw (only lunch no dinner)

today protein shake , 1 egg scramble egg 1 slice salmon 4 dates , ate half of it and stuffed

able to drink loads of water

the suppression is unreal but I do feel a bit of hunger today just can’t eat much. no SE but TOM arrived today and the cramps is strongest I had since I was a teen hopefully it last the normal 1-2 days (lasted 3 last month on w1 of 2.5 mg)

I had incredibly strong cramps with TOM too - much worse than I've had for decades! I felt awful on Saturday/Sunday. Looked it up and apparently it is 'a thing' with MJ.

Screamindreamin · 09/04/2025 15:47

Afternoon, 1 month tomorrow since starting, and after a couple of days of awful pain from constipation, it's subsided a bit today, my own fault not enough water, I really struggle with drinks 😞, well done to everyone, keeping on and sorry @Loveab123 , I think someone posted something about smaller dosing though? Could be the answer. I hit the 1 stone mark today, yippee, I love posting here because no judgement, I think people have an idea that this drug is a miracle and you just lose weight automatically, it's still been a struggle but without the constant food noise much easier to eat sensibly. I'm having the golden dose tomorrow v nervous. Well done everyone and thanks for everyone's posts they've really helped me cos no one else in my life knows I'm doing this, my next doses are due delivery in the next couple of days, I tell my husband it's face cream 😂,it comes in plain packaging and I squirrel it away upstairs, I've ordered a bundle this time though so will have to hide it under the broccoli 🥦 in the fridge knowing he will never go there in a million years lol.

popdepop · 09/04/2025 16:37

Fatmumslim01 · 09/04/2025 13:30

Just realised it's 2.5 weeks not 3.5 so 8 pound off in 2.5 weeks! 3 pound then 3 then 2

I've also got into another stone bracket 15 now.. long may it continue. I would never have done it without MJ. Weigh in Friday. I've lost 11 pounds. Week 4 injection Friday

TryForSpring · 09/04/2025 16:41

MamaBanana12 · 09/04/2025 12:49

wow I had good suppression on 2.5mg, moved to 5mg on Monday and I havnt eaten in 2 days - nausea is not too bad but every bit of food disgusts me!!
im sat in front of a chicken salad wrap and ive eaten 5 prunes (constipation fun)

weighed in again though and have lost 19lbs since 3rd march but I just need to start eating! But I have no interest.

I do intermittent fasting normally. So don’t start eating til 12pm anyway but I didn’t have anything yesterday and I’m still not fussed now

This sounds like a perfect example of why many of the old hands who have been on it ages say as long as you have good suppression, stay on the same dose. You need to be able to eat.

MamaBanana12 · 09/04/2025 17:53

TryForSpring · 09/04/2025 16:41

This sounds like a perfect example of why many of the old hands who have been on it ages say as long as you have good suppression, stay on the same dose. You need to be able to eat.

Yeah totally. Think I’m going to drop to 3.75 next week and go from there as 5 is just crazy!
I’ve forced some food down today. But certainly too much suppression.

Fatmumslim01 · 09/04/2025 18:03

MamaBanana12 · 09/04/2025 17:53

Yeah totally. Think I’m going to drop to 3.75 next week and go from there as 5 is just crazy!
I’ve forced some food down today. But certainly too much suppression.

Oh dear I'm about to order a 5mg! Due to go up to 5mg on good Friday but if I get a golden dose from my 2.5 it will be the week after but I need the pen here incase the golden dose doesn't work.

I feel on 2.5 I'm having one day with suppression then one off

CallMeStella · 09/04/2025 18:27

Hi all

W3D3

So I woke today with slight nausea and as I got out of bed I was sick in my mouth 🤢🙈 I’ve got a shitty headache and a feeling of fullness with the nausea. If this is what you have all been experiencing then I understand why you’re not eating and dropping weight so quickly. My mood is low today and I had another night being unable to sleep, making it 4 nights in the past week or so. It must be MJ as I’m on medication to make me sleep!

I haven’t eaten anything today, I’ve been busy all day and had 2 swift feelings of hunger which quickly went back to nausea and fullness. I’ll make sure I have some sort of dinner later but generally feeling a bit poo today. I much preferred not having SE especially as I have enough health issues making me feel unwell every day, I sympathise with all of you suffering with them 🫶🏼

Oh also, the bowels are a little backlogged 😬 normally muesli keeps me regular but I think I’ll need to eat some dates and dried figs to get it going.

Today I’m really appreciating our group and having a sounding board!🙏🏼

Crikeyalmighty · 09/04/2025 18:33

@CallMeStella yep I had that for 5 days on week 1, just about to do 2nd dose and dreading it as last 2 days with no SE have been like blessed relief!! If it happens every week for 5 days I’m only doing the 1st month as I have great will power anyway - and will try something that’s easier on the stomache like Berberin and persist on 1100 Cals a day

Illbefinejustbloodyfine · 09/04/2025 18:44

Feeling cold again today, haven't had that since wk 1 . Def feel like suppression is waning, not too badly. I'll be surprised to get a loss this week though

SmallSoupcon · 09/04/2025 18:48

Illbefinejustbloodyfine · 09/04/2025 18:44

Feeling cold again today, haven't had that since wk 1 . Def feel like suppression is waning, not too badly. I'll be surprised to get a loss this week though

I got so cold I bought an Oodie! Sale price though as they're not cheap. I definitely recommend, along with thick socks 😁

CallMeStella · 09/04/2025 18:56

Crikeyalmighty · 09/04/2025 18:33

@CallMeStella yep I had that for 5 days on week 1, just about to do 2nd dose and dreading it as last 2 days with no SE have been like blessed relief!! If it happens every week for 5 days I’m only doing the 1st month as I have great will power anyway - and will try something that’s easier on the stomache like Berberin and persist on 1100 Cals a day

If you can manage losing weight without MJ I’d definitely say go for it! I have binge eating disorder and despite therapy and other attempts, I just can’t get it under control with all of my other health issues going on. I need to learn better coping mechanisms and that stuffing thousands of calories down my throat isn’t going to make me feel better.

The first few weeks/months of any new medication is always the hardest so I’m willing to stick it out. I normally feel worse than this on most days due to ME/CFS 🙈🤣

What is the other medication you mentioned?

CallMeStella · 09/04/2025 18:56

SmallSoupcon · 09/04/2025 18:48

I got so cold I bought an Oodie! Sale price though as they're not cheap. I definitely recommend, along with thick socks 😁

I’m sitting here in an oodie, a throw and my bootie slippers and I’m still freezing 🤣

CallMeStella · 09/04/2025 18:58

Oh sorry I forgot to ask, is the ‘suppression’ you all mention the feeling of fullness? Or is it a different thing? Just so I can understand my own side effects and what to expect

PlexGirl34 · 09/04/2025 18:58

Evening all hope everyone is enjoying the nice weather. Today is my first jab of 5mg. Wk 4 weight in tomorrow morning. Only other update from me is my DH knows I’m taking it now the conversation wasn’t as bad as I thought it would be.

@babyhandsrobin hru

AintNobodyHereButUsChickens · 09/04/2025 19:05

CallMeStella · 09/04/2025 18:56

I’m sitting here in an oodie, a throw and my bootie slippers and I’m still freezing 🤣

I’m delaying changing our duvet to the summer one, I’m still wrapping up in the 15tog winter one!

CallMeStella · 09/04/2025 19:07

AintNobodyHereButUsChickens · 09/04/2025 19:05

I’m delaying changing our duvet to the summer one, I’m still wrapping up in the 15tog winter one!

I’m generally a hot person but I have one of those all seasons duvets where two clip together and I use both all year round 🤣 my flat is on the colder side though so maybe that’s why

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